 Langerhans Cells
"Langerhans Cells" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Recirculating, dendritic, antigen-presenting cells containing characteristic racket-shaped granules (Birbeck granules). They are found principally in the stratum spinosum of the EPIDERMIS and are rich in Class II MAJOR HISTOCOMPATIBILITY COMPLEX molecules. Langerhans cells were the first dendritic cell to be described and have been a model of study for other dendritic cells (DCs), especially other migrating DCs such as dermal DCs and INTERSTITIAL DENDRITIC CELLS.
| Descriptor ID |
D007801
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| MeSH Number(s) |
A11.066.270.500 A11.436.270.545 A15.382.066.270.500 A15.382.812.260.500
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| Concept/Terms |
Langerhans Cells- Langerhans Cells
- Cells, Langerhans
- Epidermal Dendritic Cells
- Dendritic Cells, Epidermal
- Cell, Epidermal Dendritic
- Cells, Epidermal Dendritic
- Dendritic Cell, Epidermal
- Epidermal Dendritic Cell
Skin Dendritic Cells- Skin Dendritic Cells
- Cell, Skin Dendritic
- Cells, Skin Dendritic
- Dendritic Cell, Skin
- Skin Dendritic Cell
- Dendritic Cells, Skin
Dermal Dendritic Cells- Dermal Dendritic Cells
- Cell, Dermal Dendritic
- Cells, Dermal Dendritic
- Dendritic Cell, Dermal
- Dermal Dendritic Cell
- Dendritic Cells, Dermal
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Below are MeSH descriptors whose meaning is more general than "Langerhans Cells".
Below are MeSH descriptors whose meaning is more specific than "Langerhans Cells".
This graph shows the total number of publications written about "Langerhans Cells" by people in this website by year, and whether "Langerhans Cells" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1997 | 2 | 0 | 2 | | 2001 | 1 | 1 | 2 | | 2004 | 1 | 0 | 1 | | 2007 | 1 | 0 | 1 | | 2008 | 0 | 1 | 1 | | 2011 | 0 | 2 | 2 |
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Below are the most recent publications written about "Langerhans Cells" by people in Profiles.
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Fuhlbrigge RC, Chaiban R. The immune system, the skin, and childhood rheumatic disease. Curr Rheumatol Rep. 2011 Apr; 13(2):103-9.
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Hariharan V, Toole T, Klarquist J, Mosenson J, Longley BJ, Le Poole IC. Topical application of bleaching phenols; in-vivo studies and mechanism of action relevant to melanoma treatment. Melanoma Res. 2011 Apr; 21(2):115-26.
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Satter EK, High WA. Langerhans cell histiocytosis: a case report and summary of the current recommendations of the Histiocyte Society. Dermatol Online J. 2008 Mar 15; 14(3):3.
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Walling DM, Ray AJ, Nichols JE, Flaitz CM, Nichols CM. Epstein-Barr virus infection of Langerhans cell precursors as a mechanism of oral epithelial entry, persistence, and reactivation. J Virol. 2007 Jul; 81(13):7249-68.
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Harman AN, Wilkinson J, Bye CR, Bosnjak L, Stern JL, Nicholle M, Lai J, Cunningham AL. HIV induces maturation of monocyte-derived dendritic cells and Langerhans cells. J Immunol. 2006 Nov 15; 177(10):7103-13.
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Walling DM, Flaitz CM, Hosein FG, Montes-Walters M, Nichols CM. Effect of Epstein-Barr virus replication on Langerhans cells in pathogenesis of oral hairy leukoplakia. J Infect Dis. 2004 May 01; 189(9):1656-63.
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Boguniewicz M, Leung DY. Pathophysiologic mechanisms in atopic dermatitis. Semin Cutan Med Surg. 2001 Dec; 20(4):217-25.
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Larregina AT, Morelli AE, Spencer LA, Logar AJ, Watkins SC, Thomson AW, Falo LD. Dermal-resident CD14+ cells differentiate into Langerhans cells. Nat Immunol. 2001 Dec; 2(12):1151-8.
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Borkowski TA, Letterio JJ, Mackall CL, Saitoh A, Wang XJ, Roop DR, Gress RE, Udey MC. A role for TGFbeta1 in langerhans cell biology. Further characterization of the epidermal Langerhans cell defect in TGFbeta1 null mice. J Clin Invest. 1997 Aug 01; 100(3):575-81.
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Borkowski TA, Letterio JJ, Mackall CL, Saitoh A, Farr AG, Wang XJ, Roop DR, Gress RE, Udey MC. Langerhans cells in the TGF beta 1 null mouse. Adv Exp Med Biol. 1997; 417:307-10.
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