 Thromboxane A2
"Thromboxane A2" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
An unstable intermediate between the prostaglandin endoperoxides and thromboxane B2. The compound has a bicyclic oxaneoxetane structure. It is a potent inducer of platelet aggregation and causes vasoconstriction. It is the principal component of rabbit aorta contracting substance (RCS).
| Descriptor ID |
D013928
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| MeSH Number(s) |
D10.251.355.255.100.825.800 D10.251.355.310.166.971.800
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| Concept/Terms |
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Below are MeSH descriptors whose meaning is more general than "Thromboxane A2".
Below are MeSH descriptors whose meaning is more specific than "Thromboxane A2".
This graph shows the total number of publications written about "Thromboxane A2" by people in this website by year, and whether "Thromboxane A2" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1996 | 0 | 1 | 1 | | 2002 | 1 | 0 | 1 | | 2009 | 0 | 1 | 1 | | 2016 | 1 | 0 | 1 |
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Below are the most recent publications written about "Thromboxane A2" by people in Profiles.
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Naik MU, Patel P, Derstine R, Turaga R, Chen X, Golla K, Neeves KB, Ichijo H, Naik UP. Ask1 regulates murine platelet granule secretion, thromboxane A2 generation, and thrombus formation. Blood. 2017 03 02; 129(9):1197-1209.
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Capra V, Rovati GE, Mangano P, Buccellati C, Murphy RC, Sala A. Transcellular biosynthesis of eicosanoid lipid mediators. Biochim Biophys Acta. 2015 Apr; 1851(4):377-82.
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Chari R, Getz T, Nagy B, Bhavaraju K, Mao Y, Bynagari YS, Murugappan S, Nakayama K, Kunapuli SP. Protein kinase C[delta] differentially regulates platelet functional responses. Arterioscler Thromb Vasc Biol. 2009 May; 29(5):699-705.
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Shizukuda Y, Buttrick PM. Protein kinase C-zeta modulates thromboxane A(2)-mediated apoptosis in adult ventricular myocytes via Akt. Am J Physiol Heart Circ Physiol. 2002 Jan; 282(1):H320-7.
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Sheridan BC, McIntyre RC, Meldrum DR, Cleveland JC, Agrafojo J, Banerjee A, Harken AH, Fullerton DA. Microtubules regulate pulmonary vascular smooth muscle contraction. J Surg Res. 1996 May; 62(2):284-7.
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Huang YC, Nozik ES, Piantadosi CA. Superoxide dismutase potentiates platelet-activating factor-induced injury in perfused lung. Am J Physiol. 1994 Mar; 266(3 Pt 1):L246-54.
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Maclouf J, Murphy RC, Henson PM. Transcellular biosynthesis of sulfidopeptide leukotrienes during receptor-mediated stimulation of human neutrophil/platelet mixtures. Blood. 1990 Nov 01; 76(9):1838-44.
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Helbig H, Kittredge KL, Gurley RC, Thurau SR, Palestine AG, Nussenblatt RB. Endotoxin-induced production of inflammatory mediators by cultured ciliary epithelial cells. Curr Eye Res. 1990 May; 9(5):501-5.
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Mueller HS, Rao PS, Greenberg MA, Buttrick PM, Sussman II, Levite HA, Grose RM, Perez-Davila V, Strain JE, Spaet TH. Platelet hyperactivity in acute myocardial infarction in man--effects of prostacyclin. Herz. 1986 Apr; 11(2):116-26.
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Altiere RJ, Kiritsy-Roy JA, Catravas JD. Acetylcholine-induced contractions in isolated rabbit pulmonary arteries: role of thromboxane A2. J Pharmacol Exp Ther. 1986 Feb; 236(2):535-41.
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