 Pentylenetetrazole
"Pentylenetetrazole" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A pharmaceutical agent that displays activity as a central nervous system and respiratory stimulant. It is considered a non-competitive GAMMA-AMINOBUTYRIC ACID antagonist. Pentylenetetrazole has been used experimentally to study seizure phenomenon and to identify pharmaceuticals that may control seizure susceptibility.
| Descriptor ID |
D010433
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| MeSH Number(s) |
D03.383.066.600
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| Concept/Terms |
Pentylenetetrazole- Pentylenetetrazole
- Pentylenetetrazol
- Pentetrazole
- Leptazole
- Pentamethylenetetrazole
Corasol- Corasol
- Corazole
- Korazole
- Corazol
- Korazol
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Below are MeSH descriptors whose meaning is more general than "Pentylenetetrazole".
Below are MeSH descriptors whose meaning is more specific than "Pentylenetetrazole".
This graph shows the total number of publications written about "Pentylenetetrazole" by people in this website by year, and whether "Pentylenetetrazole" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 2017 | 0 | 1 | 1 |
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Below are the most recent publications written about "Pentylenetetrazole" by people in Profiles.
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Rudy M, Mayer-Proschel M. Iron Deficiency Affects Seizure Susceptibility in a Time- and Sex-Specific Manner. ASN Neuro. 2017 Nov-Dec; 9(6):1759091417746521.
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Vendramin Pasquetti M, Meier L, Loureiro S, Ganzella M, Junges B, Barbieri Caus L, Umpierrez Amaral A, Koeller DM, Goodman S, Woontner M, Gomes de Souza DO, Wajner M, Calcagnotto ME. Impairment of GABAergic system contributes to epileptogenesis in glutaric acidemia type I. Epilepsia. 2017 10; 58(10):1771-1781.
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Naydenov AV, Horne EA, Cheah CS, Swinney K, Hsu KL, Cao JK, Marrs W, Blankman JL, Tu S, Cherry AE, Fung S, Wen A, Li W, Saporito MS, Selley DE, Cravatt BF, Oakley JC, Stella N. ABHD6 blockade exerts antiepileptic activity in PTZ-induced seizures and in spontaneous seizures in R6/2 mice. Neuron. 2014 Jul 16; 83(2):361-371.
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Ritzmann RF, Tabakoff B. Dissociation of alcohol tolerance and dependence. Nature. 1976 Sep 30; 263(5576):418-20.
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Tabakoff B, Boggan WO. Effects of ethanol on serotonin metabolism in brain. J Neurochem. 1974 May; 22(5):759-64.
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