 Polyunsaturated Alkamides
"Polyunsaturated Alkamides" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Amides composed of unsaturated aliphatic FATTY ACIDS linked with AMINES by an amide bond. They are most prominent in ASTERACEAE; PIPERACEAE; and RUTACEAE; and also found in ARISTOLOCHIACEAE; BRASSICACEAE; CONVOLVULACEAE; EUPHORBIACEAE; MENISPERMACEAE; POACEAE; and SOLANACEAE. They are recognized by their pungent taste and for causing numbing and salivation.
| Descriptor ID |
D053284
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| MeSH Number(s) |
D02.065.160 D02.455.326.271.060 D02.455.326.397.675
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| Concept/Terms |
Polyunsaturated Alkamides- Polyunsaturated Alkamides
- Alkamides, Polyunsaturated
- Alkylamides, Polyunsaturated
- Polyunsaturated Alkylamides
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Below are MeSH descriptors whose meaning is more general than "Polyunsaturated Alkamides".
Below are MeSH descriptors whose meaning is more specific than "Polyunsaturated Alkamides".
This graph shows the total number of publications written about "Polyunsaturated Alkamides" by people in this website by year, and whether "Polyunsaturated Alkamides" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2008 | 1 | 0 | 1 | | 2013 | 0 | 1 | 1 | | 2014 | 1 | 1 | 2 | | 2016 | 0 | 1 | 1 | | 2019 | 0 | 1 | 1 | | 2022 | 0 | 1 | 1 | | 2025 | 1 | 0 | 1 |
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Below are the most recent publications written about "Polyunsaturated Alkamides" by people in Profiles.
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Basu A, Pommerolle L, Arif M, Meliton AY, Udofia I, Wu D, Mutlu GM, Gochuico BR, Summer R, Adegunsoye A, Burnham EL, Cinar R. Elevated blood anandamide levels in acute COVID-19 pneumonia with respiratory failure. Am J Med Sci. 2025 Sep; 370(3):271-277.
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Ye M, Monroe SK, Gay SM, Armstrong ML, Youngstrom DE, Urbina FL, Gupton SL, Reisdorph N, Diering GH. Coordinated Regulation of CB1 Cannabinoid Receptors and Anandamide Metabolism Stabilizes Network Activity during Homeostatic Downscaling. eNeuro. 2022 Nov-Dec; 9(6).
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Kumar A, Mishra AK, Singh V, Yadav S, Saxena A, Garg SK, Swain DK. Molecular and functional insights into Transient Receptor Potential Vanilloid 1 (TRPV1) in bull spermatozoa. Theriogenology. 2019 Apr 01; 128:207-217.
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Walker VJ, Griffin AP, Hammar DK, Hollenberg PF. Metabolism of Anandamide by Human Cytochrome P450 2J2 in the Reconstituted System and Human Intestinal Microsomes. J Pharmacol Exp Ther. 2016 06; 357(3):537-44.
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Demers CH, Drabant Conley E, Bogdan R, Hariri AR. Interactions Between Anandamide and Corticotropin-Releasing Factor Signaling Modulate Human Amygdala Function and Risk for Anxiety Disorders: An Imaging Genetics Strategy for Modeling Molecular Interactions. Biol Psychiatry. 2016 09 01; 80(5):356-62.
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Fonseca BM, Battista N, Correia-da-Silva G, Rapino C, Maccarrone M, Teixeira NA. Activity of anandamide (AEA) metabolic enzymes in rat placental bed. Reprod Toxicol. 2014 Nov; 49:74-7.
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Pandey MK, DeGrado TR, Qian K, Jacobson MS, Hagen CE, Duclos RI, Gatley SJ. Synthesis and preliminary evaluation of N-(16-18F-fluorohexadecanoyl)ethanolamine (18F-FHEA) as a PET probe of N-acylethanolamine metabolism in mouse brain. ACS Chem Neurosci. 2014 Sep 17; 5(9):793-802.
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Kwilasz AJ, Abdullah RA, Poklis JL, Lichtman AH, Negus SS. Effects of the fatty acid amide hydrolase inhibitor URB597 on pain-stimulated and pain-depressed behavior in rats. Behav Pharmacol. 2014 Apr; 25(2):119-29.
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Oleson EB, Cachope R, Fitoussi A, Tsutsui K, Wu S, Gallegos JA, Cheer JF. Cannabinoid receptor activation shifts temporally engendered patterns of dopamine release. Neuropsychopharmacology. 2014 May; 39(6):1441-52.
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Snider NT, Sikora MJ, Sridar C, Feuerstein TJ, Rae JM, Hollenberg PF. The endocannabinoid anandamide is a substrate for the human polymorphic cytochrome P450 2D6. J Pharmacol Exp Ther. 2008 Nov; 327(2):538-45.
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