SGLT2 inhibition modulates metabolic, vascular, and inflammatory molecular markers in the kidney in youth with type 1 diabetes.
Bjornstad P, Choi YJ, Narongkiatikhun P, Karihaloo A, Prasad PV, Li LP, Tommerdahl KL, Sethi M, Ramesh S, Birznieks C, Clarke A, Elia Y, Curtis J, Clarson C, Weissenkampen D, D'Antonio M, Pinzon Cortes JA, Hampson H, Yuan L, van Eeghen SA, Kanter JE, Bornfeldt KE, Vaisar T, Ladd P, Heerspink HJL, de Boer IH, Goodrich JA, Street K, Tuttle KR, Bergmann KR, Smith C, Hodgin JB, Schaub JA, Nair V, Menon R, Naik AS, McCown PJ, AlAkwaa F, Eddy S, Otto E, Kim NH, Nelson RG, Puelles VG, van Raalte DH, Cherney DZI, Pyle L, Mahmud FH, Kretzler M. SGLT2 inhibition modulates metabolic, vascular, and inflammatory molecular markers in the kidney in youth with type 1 diabetes. Sci Transl Med. 2026 Jul 22; 18(859):eaee1005.
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