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Robert Acton Jacobs

TitleAssociate Professor
InstitutionUniversity of Colorado Colorado Springs
DepartmentBeth-El Human Physio/Nutrition
Phone719/255-3638

    Collapse Bibliographic 
    Collapse selected publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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    1. Walsh MA, Latham AS, Zhang Q, Jacobs RA, Musci RV, LaRocca TJ, Moreno JA, Santangelo KS, Hamilton KL. Non-transgenic guinea pig strains exhibit divergent age-related changes in hippocampal mitochondrial respiration. Acta Physiol (Oxf). 2024 Aug; 240(8):e14185. PMID: 38860650.
      View in: PubMed
    2. Lukasiewicz CJ, Vandiver KJ, Albert ED, Kirby BS, Jacobs RA. Assessing exogenous carbohydrate intake needed to optimize human endurance performance across sex: insights from modeling runners pursuing a sub-2-h marathon. J Appl Physiol (1985). 2024 Jan 01; 136(1):158-176. PMID: 38059288.
      View in: PubMed
    3. Schytz CT, ?rtenblad N, Lundby AM, Jacobs RA, Nielsen J, Lundby C. Skeletal muscle mitochondria demonstrate similar respiration per cristae surface area independent of training status and sex in healthy humans. J Physiol. 2024 Jan; 602(1):129-151. PMID: 38051639.
      View in: PubMed
    4. Walsh MA, Musci RV, Jacobs RA, Hamilton KL. A practical perspective on how to develop, implement, execute, and reproduce high-resolution respirometry experiments: The physiologist's guide to an Oroboros O2k. FASEB J. 2023 12; 37(12):e23280. PMID: 37899680.
      View in: PubMed
    5. Jacobs RA, Lundby C. Contextualizing the biological relevance of standardized high-resolution respirometry to assess mitochondrial function in permeabilized human skeletal muscle. Acta Physiol (Oxf). 2021 04; 231(4):e13625. PMID: 33570804.
      View in: PubMed
    6. Trotter CE, Tourula E, Pizzey FK, Batterson PM, Jacobs RA, Pearson J. High-intensity interval exercise reduces tolerance to a simulated haemorrhagic challenge in heat-stressed individuals. Exp Physiol. 2021 01; 106(1):212-221. PMID: 32003866.
      View in: PubMed
    7. Batterson PM, Norton MR, Hetz SE, Rohilla S, Lindsay KG, Subudhi AW, Jacobs RA. Improving biologic predictors of cycling endurance performance with near-infrared spectroscopy derived measures of skeletal muscle respiration: E pluribus unum. Physiol Rep. 2020 01; 8(2):e14342. PMID: 31960629.
      View in: PubMed
    8. Williams KA, Bell K, Jacobs RA, Subudhi AW. Supplemental Oxygen Does Not Influence Self-selected Work Rate at Moderate Altitude. Med Sci Sports Exerc. 2019 03; 51(3):575-581. PMID: 30299413.
      View in: PubMed
    9. Trotter CE, Pizzey FK, Batterson PM, Jacobs RA, Pearson J. Small reductions in skin temperature after onset of a simulated hemorrhagic challenge improve tolerance in exercise heat-stressed individuals. Am J Physiol Regul Integr Comp Physiol. 2018 09 01; 315(3):R539-R546. PMID: 30088981.
      View in: PubMed
    10. Chung S, Nelson MD, Hamaoka T, Jacobs RA, Pearson J, Subudhi AW, Jenkins NT, Bartlett MF, Fitzgerald LF, Miehm JD, Kent JA, Lucero AA, Rowlands DS, Stoner L, McCully KK, Call J, Rodriguez-Miguelez P, Harris RA, Porcelli S, Rasica L, Marzorati M, Quaresima V, Ryan TE, Vernillo G, Millet GP, Malatesta D, Millet GY, Zuo L, Chuang CC. Commentaries on Viewpoint: Principles, insights, and potential pitfalls of the noninvasive determination of muscle oxidative capacity by near-infrared spectroscopy. J Appl Physiol (1985). 2018 01 01; 124(1):249-255. PMID: 29364790.
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    11. Christensen PM, Jacobs RA, Bonne T, Fl?ck D, Bangsbo J, Lundby C. A short period of high-intensity interval training improves skeletal muscle mitochondrial function and pulmonary oxygen uptake kinetics. J Appl Physiol (1985). 2016 Jun 01; 120(11):1319-27. PMID: 26846547.
      View in: PubMed
    12. Sch?nenberger D, Harlander S, Rajski M, Jacobs RA, Lundby AK, Adlesic M, Hejhal T, Wild PJ, Lundby C, Frew IJ. Formation of Renal Cysts and Tumors in Vhl/Trp53-Deficient Mice Requires HIF1a and HIF2a. Cancer Res. 2016 04 01; 76(7):2025-36. PMID: 26759234.
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    13. Lundby C, Jacobs RA. Adaptations of skeletal muscle mitochondria to exercise training. Exp Physiol. 2016 Jan; 101(1):17-22. PMID: 26440213.
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    14. Jacobs RA, Lundby AK, Fenk S, Gehrig S, Siebenmann C, Fl?ck D, Kirk N, Hilty MP, Lundby C. Twenty-eight days of exposure to 3454 m increases mitochondrial volume density in human skeletal muscle. J Physiol. 2016 Mar 01; 594(5):1151-66. PMID: 26339730.
      View in: PubMed
    15. Montero D, Cathomen A, Jacobs RA, Fl?ck D, de Leur J, Keiser S, Bonne T, Kirk N, Lundby AK, Lundby C. Haematological rather than skeletal muscle adaptations contribute to the increase in peak oxygen uptake induced by moderate endurance training. J Physiol. 2015 Oct 15; 593(20):4677-88. PMID: 26282186.
      View in: PubMed
    16. Robach P, Bonne T, Fl?ck D, B?rgi S, Toigo M, Jacobs RA, Lundby C. Hypoxic training: effect on mitochondrial function and aerobic performance in hypoxia. Med Sci Sports Exerc. 2014 Oct; 46(10):1936-45. PMID: 24674976.
      View in: PubMed
    17. Bonne TC, Doucende G, Fl?ck D, Jacobs RA, Nordsborg NB, Robach P, Walther G, Lundby C. Phlebotomy eliminates the maximal cardiac output response to six weeks of exercise training. Am J Physiol Regul Integr Comp Physiol. 2014 May 15; 306(10):R752-60. PMID: 24622974.
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    18. Jacobs RA. Con: Live high-train low does not improve sea-level performance beyond that achieved with the equivalent living and training at sea level. High Alt Med Biol. 2013 Dec; 14(4):328-30. PMID: 24377336.
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    19. Jacobs RA. Rebuttal to the pro statement. High Alt Med Biol. 2013 Dec; 14(4):333. PMID: 24377338.
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    20. Jacobs RA, Fl?ck D, Bonne TC, B?rgi S, Christensen PM, Toigo M, Lundby C. Improvements in exercise performance with high-intensity interval training coincide with an increase in skeletal muscle mitochondrial content and function. J Appl Physiol (1985). 2013 Sep; 115(6):785-93. PMID: 23788574.
      View in: PubMed
    21. Jacobs RA, Meinild AK, Nordsborg NB, Lundby C. Lactate oxidation in human skeletal muscle mitochondria. Am J Physiol Endocrinol Metab. 2013 Apr 01; 304(7):E686-94. PMID: 23384769.
      View in: PubMed
    22. Jacobs RA, D?az V, Soldini L, Haider T, Thomassen M, Nordsborg NB, Gassmann M, Lundby C. Fast-twitch glycolytic skeletal muscle is predisposed to age-induced impairments in mitochondrial function. J Gerontol A Biol Sci Med Sci. 2013 Sep; 68(9):1010-22. PMID: 23371970.
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    23. Jacobs RA, Lundby C. Mitochondria express enhanced quality as well as quantity in association with aerobic fitness across recreationally active individuals up to elite athletes. J Appl Physiol (1985). 2013 Feb; 114(3):344-50. PMID: 23221957.
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    24. Jacobs RA, D?az V, Meinild AK, Gassmann M, Lundby C. The C57Bl/6 mouse serves as a suitable model of human skeletal muscle mitochondrial function. Exp Physiol. 2013 Apr; 98(4):908-21. PMID: 23180810.
      View in: PubMed
    25. Jacobs RA, Siebenmann C, Hug M, Toigo M, Meinild AK, Lundby C. Twenty-eight days at 3454-m altitude diminishes respiratory capacity but enhances efficiency in human skeletal muscle mitochondria. FASEB J. 2012 Dec; 26(12):5192-200. PMID: 22968913.
      View in: PubMed
    26. Siebenmann C, S?rensen H, Jacobs RA, Haider T, Rasmussen P, Lundby C. Hypocapnia during hypoxic exercise and its impact on cerebral oxygenation, ventilation and maximal whole body O2 uptake. Respir Physiol Neurobiol. 2013 Jan 15; 185(2):461-7. PMID: 22922610.
      View in: PubMed
    27. Jacobs RA, Lundby C, Robach P, Gassmann M. Red blood cell volume and the capacity for exercise at moderate to high altitude. Sports Med. 2012 Aug 01; 42(8):643-63. PMID: 22741918.
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    28. Robach P, Siebenmann C, Jacobs RA, Rasmussen P, Nordsborg N, Pesta D, Gnaiger E, D?az V, Christ A, Fiedler J, Crivelli N, Secher NH, Pichon A, Maggiorini M, Lundby C. The role of haemoglobin mass on VO(2)max following normobaric 'live high-train low' in endurance-trained athletes. Br J Sports Med. 2012 Sep; 46(11):822-7. PMID: 22790809.
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    29. Schuler B, Vogel J, Grenacher B, Jacobs RA, Arras M, Gassmann M. Acute and chronic elevation of erythropoietin in the brain improves exercise performance in mice without inducing erythropoiesis. FASEB J. 2012 Sep; 26(9):3884-90. PMID: 22683849.
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    30. Jacobs RA, Boushel R, Wright-Paradis C, Calbet JA, Robach P, Gnaiger E, Lundby C. Mitochondrial function in human skeletal muscle following high-altitude exposure. Exp Physiol. 2013 Jan; 98(1):245-55. PMID: 22636256.
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    31. Rasmussen P, Nordsborg N, Taudorf S, S?rensen H, Berg RM, Jacobs RA, Bailey DM, Olsen NV, Secher NH, M?ller K, Lundby C. Brain and skin do not contribute to the systemic rise in erythropoietin during acute hypoxia in humans. FASEB J. 2012 May; 26(5):1831-4. PMID: 22321729.
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    32. Siebenmann C, Robach P, Jacobs RA, Rasmussen P, Nordsborg N, Diaz V, Christ A, Olsen NV, Maggiorini M, Lundby C. "Live high-train low" using normobaric hypoxia: a double-blinded, placebo-controlled study. J Appl Physiol (1985). 2012 Jan; 112(1):106-17. PMID: 22033534.
      View in: PubMed
    33. Jacobs RA, Donovan EL, Robinson MM. Parallels of snipe hunting and ROS research: the challenges of studying ROS and redox signalling in response to exercise. J Physiol. 2009 Mar 01; 587(Pt 5):927-8. PMID: 19124537.
      View in: PubMed
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