 Connection
Lori Sussel to Cell Differentiation
This is a "connection" page, showing publications Lori Sussel has written about Cell Differentiation.
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Connection Strength |
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3.732 |
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Romer AI, Singer RA, Sui L, Egli D, Sussel L. Murine Perinatal ß-Cell Proliferation and the Differentiation of Human Stem Cell-Derived Insulin-Expressing Cells Require NEUROD1. Diabetes. 2019 12; 68(12):2259-2271.
Score: 0.346
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Churchill AJ, Gutiérrez GD, Singer RA, Lorberbaum DS, Fischer KA, Sussel L. Genetic evidence that Nkx2.2 acts primarily downstream of Neurog3 in pancreatic endocrine lineage development. Elife. 2017 01 10; 6.
Score: 0.287
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Gross S, Balderes D, Liu J, Asfaha S, Gu G, Wang TC, Sussel L. Nkx2.2 is expressed in a subset of enteroendocrine cells with expanded lineage potential. Am J Physiol Gastrointest Liver Physiol. 2015 Dec 15; 309(12):G975-87.
Score: 0.264
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Romer AI, Sussel L. Pancreatic islet cell development and regeneration. Curr Opin Endocrinol Diabetes Obes. 2015 Aug; 22(4):255-64.
Score: 0.260
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Mastracci TL, Anderson KR, Papizan JB, Sussel L. Regulation of Neurod1 contributes to the lineage potential of Neurogenin3+ endocrine precursor cells in the pancreas. PLoS Genet. 2013; 9(2):e1003278.
Score: 0.219
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Mastracci TL, Sussel L. The endocrine pancreas: insights into development, differentiation, and diabetes. Wiley Interdiscip Rev Dev Biol. 2012 Sep-Oct; 1(5):609-28.
Score: 0.206
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Anderson KR, Singer RA, Balderes DA, Hernandez-Lagunas L, Johnson CW, Artinger KB, Sussel L. The L6 domain tetraspanin Tm4sf4 regulates endocrine pancreas differentiation and directed cell migration. Development. 2011 Aug; 138(15):3213-24.
Score: 0.197
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Doyle MJ, Sussel L. Nkx2.2 regulates beta-cell function in the mature islet. Diabetes. 2007 Aug; 56(8):1999-2007.
Score: 0.146
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Brooks EP, Casey MR, Wells KL, Liu TY, Van Orman M, Sussel L. NKX2.2 and KLF4 cooperate to regulate a-cell identity. Genes Dev. 2025 02 03; 39(3-4):242-260.
Score: 0.126
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Brooks EP, Sussel L. Not the second fiddle: a cell development, identity, and function in health and diabetes. J Endocrinol. 2023 08 01; 258(2).
Score: 0.113
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Abarinov V, Levine JA, Churchill AJ, Hopwood B, Deiter CS, Guney MA, Wells KL, Schrunk JM, Guo Y, Hammelman J, Gifford DK, Magnuson MA, Wichterle H, Sussel L. Major ß cell-specific functions of NKX2.2 are mediated via the NK2-specific domain. Genes Dev. 2023 06 01; 37(11-12):490-504.
Score: 0.112
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Russ HA, Shilleh AH, Sussel L. From the dish to humans: A stem cell recipe for success. Cell Metab. 2022 02 01; 34(2):193-196.
Score: 0.102
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Theis A, Singer RA, Garofalo D, Paul A, Narayana A, Sussel L. Groucho co-repressor proteins regulate ß cell development and proliferation by repressing Foxa1 in the developing mouse pancreas. Development. 2021 03 24; 148(6).
Score: 0.096
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Docherty FM, Sussel L. Islet Regeneration: Endogenous and Exogenous Approaches. Int J Mol Sci. 2021 Mar 24; 22(7).
Score: 0.096
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Pajvani UB, Sussel L. An Ultradian Notch in Beta-Cell Development. N Engl J Med. 2020 07 02; 383(1):80-82.
Score: 0.091
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Lorberbaum DS, Kishore S, Rosselot C, Sarbaugh D, Brooks EP, Aragon E, Xuan S, Simon O, Ghosh D, Mendelsohn C, Gadue P, Sussel L. Retinoic acid signaling within pancreatic endocrine progenitors regulates mouse and human ß cell specification. Development. 2020 06 22; 147(12).
Score: 0.091
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Lorberbaum DS, Sussel L. A Notch in Time: Spatiotemporal Analysis of Notch Signaling during Pancreas Development. Dev Cell. 2020 03 23; 52(6):681-682.
Score: 0.090
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Lorberbaum DS, Sussel L. Gotta Have GATA for Human Pancreas Development. Cell Stem Cell. 2017 05 04; 20(5):577-579.
Score: 0.073
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Ediger BN, Lim HW, Juliana C, Groff DN, Williams LT, Dominguez G, Liu JH, Taylor BL, Walp ER, Kameswaran V, Yang J, Liu C, Hunter CS, Kaestner KH, Naji A, Li C, Sander M, Stein R, Sussel L, Won KJ, May CL, Stoffers DA. LIM domain-binding 1 maintains the terminally differentiated state of pancreatic ß cells. J Clin Invest. 2017 01 03; 127(1):215-229.
Score: 0.071
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Arnes L, Sussel L. Epigenetic modifications and long noncoding RNAs influence pancreas development and function. Trends Genet. 2015 Jun; 31(6):290-9.
Score: 0.063
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Clark JK, O'keefe A, Mastracci TL, Sussel L, Matise MP, Kucenas S. Mammalian Nkx2.2+ perineurial glia are essential for motor nerve development. Dev Dyn. 2014 Sep; 243(9):1116-29.
Score: 0.060
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Zhu Q, Zhao X, Zheng K, Li H, Huang H, Zhang Z, Mastracci T, Wegner M, Chen Y, Sussel L, Qiu M. Genetic evidence that Nkx2.2 and Pdgfra are major determinants of the timing of oligodendrocyte differentiation in the developing CNS. Development. 2014 Feb; 141(3):548-55.
Score: 0.059
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Arnes L, Hill JT, Gross S, Magnuson MA, Sussel L. Ghrelin expression in the mouse pancreas defines a unique multipotent progenitor population. PLoS One. 2012; 7(12):e52026.
Score: 0.054
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Xuan S, Borok MJ, Decker KJ, Battle MA, Duncan SA, Hale MA, Macdonald RJ, Sussel L. Pancreas-specific deletion of mouse Gata4 and Gata6 causes pancreatic agenesis. J Clin Invest. 2012 Oct; 122(10):3516-28.
Score: 0.053
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Papizan JB, Singer RA, Tschen SI, Dhawan S, Friel JM, Hipkens SB, Magnuson MA, Bhushan A, Sussel L. Nkx2.2 repressor complex regulates islet ß-cell specification and prevents ß-to-a-cell reprogramming. Genes Dev. 2011 Nov 01; 25(21):2291-305.
Score: 0.050
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Roybon L, Mastracci TL, Ribeiro D, Sussel L, Brundin P, Li JY. GABAergic differentiation induced by Mash1 is compromised by the bHLH proteins Neurogenin2, NeuroD1, and NeuroD2. Cereb Cortex. 2010 May; 20(5):1234-44.
Score: 0.043
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Hill JT, Mastracci TL, Vinton C, Doyle ML, Anderson KR, Loomis ZL, Schrunk JM, Minic AD, Prabakar KR, Pugliese A, Sun Y, Smith RG, Sussel L. Ghrelin is dispensable for embryonic pancreatic islet development and differentiation. Regul Pept. 2009 Oct 09; 157(1-3):51-6.
Score: 0.042
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Chao CS, Loomis ZL, Lee JE, Sussel L. Genetic identification of a novel NeuroD1 function in the early differentiation of islet alpha, PP and epsilon cells. Dev Biol. 2007 Dec 15; 312(2):523-32.
Score: 0.038
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Desai S, Loomis Z, Pugh-Bernard A, Schrunk J, Doyle MJ, Minic A, McCoy E, Sussel L. Nkx2.2 regulates cell fate choice in the enteroendocrine cell lineages of the intestine. Dev Biol. 2008 Jan 01; 313(1):58-66.
Score: 0.038
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Doyle MJ, Loomis ZL, Sussel L. Nkx2.2-repressor activity is sufficient to specify alpha-cells and a small number of beta-cells in the pancreatic islet. Development. 2007 Feb; 134(3):515-23.
Score: 0.036
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Decker K, Goldman DC, Grasch CL, Sussel L. Gata6 is an important regulator of mouse pancreas development. Dev Biol. 2006 Oct 15; 298(2):415-29.
Score: 0.035
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Prakash N, Brodski C, Naserke T, Puelles E, Gogoi R, Hall A, Panhuysen M, Echevarria D, Sussel L, Weisenhorn DM, Martinez S, Arenas E, Simeone A, Wurst W. A Wnt1-regulated genetic network controls the identity and fate of midbrain-dopaminergic progenitors in vivo. Development. 2006 Jan; 133(1):89-98.
Score: 0.033
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Bandral M, Sussel L, Lorberbaum DS. Retinoid signaling in pancreas development, islet function, and disease. Curr Top Dev Biol. 2025; 161:297-318.
Score: 0.031
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Doyle MJ, Sussel L. Engineering islets: lessons from stem cells and embryonic development. Endocrinol Metab Clin North Am. 2004 Mar; 33(1):149-62, x.
Score: 0.029
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Wang J, Elghazi L, Parker SE, Kizilocak H, Asano M, Sussel L, Sosa-Pineda B. The concerted activities of Pax4 and Nkx2.2 are essential to initiate pancreatic beta-cell differentiation. Dev Biol. 2004 Feb 01; 266(1):178-89.
Score: 0.029
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Sussel L, Kalamaras J, Hartigan-O'Connor DJ, Meneses JJ, Pedersen RA, Rubenstein JL, German MS. Mice lacking the homeodomain transcription factor Nkx2.2 have diabetes due to arrested differentiation of pancreatic beta cells. Development. 1998 Jun; 125(12):2213-21.
Score: 0.020
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Lek M, Dias JM, Marklund U, Uhde CW, Kurdija S, Lei Q, Sussel L, Rubenstein JL, Matise MP, Arnold HH, Jessell TM, Ericson J. A homeodomain feedback circuit underlies step-function interpretation of a Shh morphogen gradient during ventral neural patterning. Development. 2010 Dec; 137(23):4051-60.
Score: 0.012
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Jedlicka P, Sui X, Sussel L, Gutierrez-Hartmann A. Ets transcription factors control epithelial maturation and transit and crypt-villus morphogenesis in the mammalian intestine. Am J Pathol. 2009 Apr; 174(4):1280-90.
Score: 0.010
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Qi Y, Cai J, Wu Y, Wu R, Lee J, Fu H, Rao M, Sussel L, Rubenstein J, Qiu M. Control of oligodendrocyte differentiation by the Nkx2.2 homeodomain transcription factor. Development. 2001 Jul; 128(14):2723-33.
Score: 0.006
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Sander M, Sussel L, Conners J, Scheel D, Kalamaras J, Dela Cruz F, Schwitzgebel V, Hayes-Jordan A, German M. Homeobox gene Nkx6.1 lies downstream of Nkx2.2 in the major pathway of beta-cell formation in the pancreas. Development. 2000 Dec; 127(24):5533-40.
Score: 0.006
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Connection Strength
The connection strength for concepts is the sum of the scores for each matching publication.
Publication scores are based on many factors, including how long ago they were written and whether the person is a first or senior author.
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