 Connection
Lori Sussel to Insulin
This is a "connection" page, showing publications Lori Sussel has written about Insulin.
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Connection Strength |
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1.252 |
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Bluestone JA, Herold KC, Sussel L. Type 1 Diabetes: Advances in Understanding and Treatment 100 Years after the Discovery of Insulin. Cold Spring Harb Perspect Med. 2026 05 01; 16(5).
Score: 0.440
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Sarbaugh D, Oliveira TG, Guney MA, Casey MR, Hoelscher VM, Hill CJ, Michel CR, Wells KL, Benninger RKP, Sussel L. CHD4 and NKX2.2 Cooperate to Regulate ß-Cell Function by Repressing Non-ß-Cell Gene Programs. Diabetes. 2026 07 01; 75(7):1189-1200.
Score: 0.111
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Haemmerle MW, Scota AV, Khosravifar M, Varney MJ, Sen S, Good AL, Yang X, Wells KL, Sussel L, Rozo AV, Doliba NM, Ghanem LR, Stoffers DA. RNA-binding protein PCBP2 regulates pancreatic ß cell function and adaptation to glucose. J Clin Invest. 2024 Jun 17; 134(12).
Score: 0.097
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Prado CL, Pugh-Bernard AE, Elghazi L, Sosa-Pineda B, Sussel L. Ghrelin cells replace insulin-producing beta cells in two mouse models of pancreas development. Proc Natl Acad Sci U S A. 2004 Mar 02; 101(9):2924-9.
Score: 0.095
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Moss ND, Wells KL, Theis A, Kim YK, Spigelman AF, Liu X, MacDonald PE, Sussel L. Modulation of insulin secretion by RBFOX2-mediated alternative splicing. Nat Commun. 2023 11 25; 14(1):7732.
Score: 0.093
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Lorberbaum DS, Kishore S, Rosselot C, Sarbaugh D, Brooks EP, Aragon E, Xuan S, Simon O, Ghosh D, Mendelsohn C, Gadue P, Sussel L. Retinoic acid signaling within pancreatic endocrine progenitors regulates mouse and human ß cell specification. Development. 2020 06 22; 147(12).
Score: 0.073
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Singer RA, Sussel L. Islet Long Noncoding RNAs: A Playbook for Discovery and Characterization. Diabetes. 2018 08; 67(8):1461-1470.
Score: 0.064
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Xuan S, Borok MJ, Decker KJ, Battle MA, Duncan SA, Hale MA, Macdonald RJ, Sussel L. Pancreas-specific deletion of mouse Gata4 and Gata6 causes pancreatic agenesis. J Clin Invest. 2012 Oct; 122(10):3516-28.
Score: 0.043
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Mastracci TL, Sussel L. The endocrine pancreas: insights into development, differentiation, and diabetes. Wiley Interdiscip Rev Dev Biol. 2012 Sep-Oct; 1(5):609-28.
Score: 0.041
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Papizan JB, Singer RA, Tschen SI, Dhawan S, Friel JM, Hipkens SB, Magnuson MA, Bhushan A, Sussel L. Nkx2.2 repressor complex regulates islet ß-cell specification and prevents ß-to-a-cell reprogramming. Genes Dev. 2011 Nov 01; 25(21):2291-305.
Score: 0.040
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Gu C, Stein GH, Pan N, Goebbels S, Hörnberg H, Nave KA, Herrera P, White P, Kaestner KH, Sussel L, Lee JE. Pancreatic beta cells require NeuroD to achieve and maintain functional maturity. Cell Metab. 2010 Apr 07; 11(4):298-310.
Score: 0.036
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Doyle MJ, Sussel L. Nkx2.2 regulates beta-cell function in the mature islet. Diabetes. 2007 Aug; 56(8):1999-2007.
Score: 0.029
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Oguh AU, Haemmerle MW, Sen S, Rozo AV, Shrestha S, Cartailler JP, Fazelinia H, Ding H, Preza S, Yang J, Yang X, Sussel L, Alvarez-Dominguez JR, Doliba N, Spruce LA, Arrojo E Drigo R, Stoffers DA. E3 ligase substrate adaptor SPOP fine-tunes the UPR of pancreatic ß cells. Genes Dev. 2025 02 03; 39(3-4):261-279.
Score: 0.025
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Cissell MA, Zhao L, Sussel L, Henderson E, Stein R. Transcription factor occupancy of the insulin gene in vivo. Evidence for direct regulation by Nkx2.2. J Biol Chem. 2003 Jan 10; 278(2):751-6.
Score: 0.022
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Sussel L, Kalamaras J, Hartigan-O'Connor DJ, Meneses JJ, Pedersen RA, Rubenstein JL, German MS. Mice lacking the homeodomain transcription factor Nkx2.2 have diabetes due to arrested differentiation of pancreatic beta cells. Development. 1998 Jun; 125(12):2213-21.
Score: 0.016
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Cui Y, Hu D, Markillie LM, Chrisler WB, Gaffrey MJ, Ansong C, Sussel L, Orr G. Fluctuation localization imaging-based fluorescence in situ hybridization (fliFISH) for accurate detection and counting of RNA copies in single cells. Nucleic Acids Res. 2018 01 25; 46(2):e7.
Score: 0.016
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Talchai C, Xuan S, Lin HV, Sussel L, Accili D. Pancreatic ß cell dedifferentiation as a mechanism of diabetic ß cell failure. Cell. 2012 Sep 14; 150(6):1223-34.
Score: 0.011
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Connection Strength
The connection strength for concepts is the sum of the scores for each matching publication.
Publication scores are based on many factors, including how long ago they were written and whether the person is a first or senior author.
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