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Anna Malykhina

TitleAssociate Professor
InstitutionUniversity of Colorado Denver - Anschutz Medical Campus
DepartmentSOM-SRG

    Collapse Research 
    Collapse research activities and funding
    R01DK077699     (MALYKHINA, ANNA P.)Jul 1, 2008 - Apr 30, 2014
    NIH/NIDDK
    Cross-sensitization in the pelvis and neurogenic bladder
    Role: Principal Investigator

    P20DK097819     (MALYKHINA, ANNA P.)Sep 29, 2012 - Jul 31, 2015
    NIH/NIDDK
    Neurogenic bladder dysfunctions in neurological disorders
    Role: Principal Investigator

    R01DK095817     (MALYKHINA, ANNA P.)Sep 8, 2014 - May 31, 2018
    NIH/NIDDK
    Role of Mechanotransduction in detrusor over activity
    Role: Principal Investigator

    Collapse Bibliographic 
    Collapse selected publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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    1. Weissbart SJ, Pechersky D, Malykhina A, Bavaria T, Parrillo L, Arya LA, Bilello M, Wein AJ, Smith AL. The impact of pontine disease on lower urinary tract symptoms in patients with multiple sclerosis. Neurourol Urodyn. 2017 Feb; 36(2):453-456. PMID: 26741487.
      View in: PubMed
    2. Hypolite JA, Malykhina AP. Regulation of urinary bladder function by protein kinase C in physiology and pathophysiology. BMC Urol. 2015 Nov 04; 15:110. PMID: 26538012.
      View in: PubMed
    3. Hypolite JA, Chang S, Wein AJ, Chacko S, Malykhina AP. Protein kinase C modulates frequency of micturition and non-voiding contractions in the urinary bladder via neuronal and myogenic mechanisms. BMC Urol. 2015 Apr 21; 15:34. PMID: 25896919.
      View in: PubMed
    4. Lamarre NS, Braverman AS, Malykhina AP, Barbe MF, Ruggieri MR. Alterations in nerve-evoked bladder contractions in a coronavirus-induced mouse model of multiple sclerosis. PLoS One. 2014; 9(10):e109314. PMID: 25310403.
      View in: PubMed
    5. Lei Q, Pan XQ, Chang S, Malkowicz SB, Guzzo TJ, Malykhina AP. Response of the human detrusor to stretch is regulated by TREK-1, a two-pore-domain (K2P) mechano-gated potassium channel. J Physiol. 2014 Jul 15; 592(14):3013-30. PMID: 24801307.
      View in: PubMed
    6. Malykhina AP, Lei Q, Chang S, Pan XQ, Villamor AN, Smith AL, Seftel AD. Bladder outlet obstruction triggers neural plasticity in sensory pathways and contributes to impaired sensitivity in erectile dysfunction. Am J Physiol Regul Integr Comp Physiol. 2013 May 15; 304(10):R837-45. PMID: 23535456.
      View in: PubMed
    7. Lei Q, Pan XQ, Villamor AN, Asfaw TS, Chang S, Zderic SA, Malykhina AP. Lack of transient receptor potential vanilloid 1 channel modulates the development of neurogenic bladder dysfunction induced by cross-sensitization in afferent pathways. J Neuroinflammation. 2013 Jan 11; 10:3. PMID: 23305398.
      View in: PubMed
    8. Hypolite JA, Lei Q, Chang S, Zderic SA, Butler S, Wein AJ, Malykhina AP, Chacko S. Spontaneous and evoked contractions are regulated by PKC-mediated signaling in detrusor smooth muscle: involvement of BK channels. Am J Physiol Renal Physiol. 2013 Mar 01; 304(5):F451-62. PMID: 23269650.
      View in: PubMed
    9. Malykhina AP, Qin C, Lei Q, Pan XQ, Greenwood-Van Meerveld B, Foreman RD. Differential effects of intravesical resiniferatoxin on excitability of bladder spinal neurons upon colon-bladder cross-sensitization. Brain Res. 2013 Jan 23; 1491:213-24. PMID: 23146715.
      View in: PubMed
    10. Asfaw TS, Hypolite J, Northington GM, Arya LA, Wein AJ, Malykhina AP. Acute colonic inflammation triggers detrusor instability via activation of TRPV1 receptors in a rat model of pelvic organ cross-sensitization. Am J Physiol Regul Integr Comp Physiol. 2011 Jun; 300(6):R1392-400. PMID: 21474425.
      View in: PubMed
    11. Pan XQ, Gonzalez JA, Chang S, Chacko S, Wein AJ, Malykhina AP. Experimental colitis triggers the release of substance P and calcitonin gene-related peptide in the urinary bladder via TRPV1 signaling pathways. Exp Neurol. 2010 Oct; 225(2):262-73. PMID: 20501335.
      View in: PubMed
    12. Noronha R, Akbarali H, Malykhina A, Foreman RD, Greenwood-Van Meerveld B. Changes in urinary bladder smooth muscle function in response to colonic inflammation. Am J Physiol Renal Physiol. 2007 Nov; 293(5):F1461-7. PMID: 17715261.
      View in: PubMed
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