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Yanjun Gao

TitleAssistant Professor
InstitutionUniversity of Colorado Denver - Anschutz Medical Campus
DepartmentSOM-BIOMED Informatics Gen Ops

    Collapse Biography 
    Collapse education and training
    Penn State University, State College, PAPhD08/2021Computer Science
    University of Wisconsin, Madison, WIPostdoc08/2024Clinical Informatics and Health AI

    Collapse Overview 
    Collapse overview
    Dr. Yanjun Gao is an Assistant Professor in the Department of Biomedical Informatics at the University of Colorado Anschutz Medical Campus. She leads the Language, Reasoning, and Knowledge (LARK) Lab, where her research focuses on developing and evaluating foundational natural language processing (NLP) methods, particularly large language models (LLMs), for healthcare applications. With expertise spanning computer science, NLP, and healthcare informatics, Dr. Gao’s work aims to transform complex data, such as electronic health records (EHRs), into actionable insights to improve decision-making and patient outcomes. Her broader vision is to ensure AI systems are safe, trustworthy, and effectively aligned with human needs.

    Collapse Bibliographic 
    Collapse selected publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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    1. Henry K, Smith B, Zhao X, Blotske K, Murray B, Gao Y, Smith SE, Barreto EF, Bauer S, Sohn S, Liu T, Bennett T, Cohen M, Abdulnour RE, Sikora A. Drug or Pokémon? An analysis of the ability of large language models to discern fabricated medications. medRxiv. 2026 Jan 13. PMID: 41646757.
      View in: PubMed
    2. Cheng H, Wu Y, Khatwani S, Kruse M, Dligach D, Miller TA, Afshar M, Gao Y. Scaling Biomedical Knowledge Graph Retrieval for Interpretable Reasoning: Applications to Clinical Diagnosis Prediction. medRxiv. 2026 Jan 13. PMID: 41646767.
      View in: PubMed
    3. Zhao X, Blotske K, Cargile M, Tilley A, Murray B, Gao Y, Henry K, Smith SE, Barreto EF, Bauer S, Sohn S, Liu T, Bennett T, Cohen M, Sikora A. Rx-LLM: a benchmarking suite to evaluate safe large language model performance for medication-related tasks. medRxiv. 2025 Dec 30. PMID: 41404284.
      View in: PubMed
    4. Blotske K, Zhao X, Henry K, Gao Y, Tilley A, Cargile M, Murray B, Smith SE, Barreto EF, Bauer S, Sohn S, Liu T, Bennett T, Cohen M, Sikora A. Drug-drug interaction identification using large language models. medRxiv. 2025 Dec 29. PMID: 41503479.
      View in: PubMed
    5. Kruse M, Afshar M, Khatwani S, Mayampurath A, Chen G, Gao Y. Simple Yet Effective: An Information-Theoretic Approach to Multi-LLM Uncertainty Quantification. Proc Conf Empir Methods Nat Lang Process. 2025 Nov; 2025:30481-30492. PMID: 41399801.
      View in: PubMed
    6. Kruse M, Hu S, Derby N, Wu Y, Stonbraker S, Yao B, Wang D, Goldberg E, Gao Y. Large Language Models with Temporal Reasoning for Longitudinal Clinical Summarization and Prediction. Find ACL EMNLP. 2025 Nov; 2025:20715-20735. PMID: 41399802.
      View in: PubMed
    7. Gao Y, Li R, Croxford E, Caskey J, Patterson BW, Churpek M, Miller T, Dligach D, Afshar M. Leveraging Medical Knowledge Graphs Into Large Language Models for Diagnosis Prediction: Design and Application Study. JMIR AI. 2025 Feb 24; 4:e58670. PMID: 39993309.
      View in: PubMed
    8. Gao Y, Myers S, Chen S, Dligach D, Miller T, Bitterman DS, Chen G, Mayampurath A, Churpek MM, Afshar M. Uncertainty estimation in diagnosis generation from large language models: next-word probability is not pre-test probability. JAMIA Open. 2025 Feb; 8(1):ooae154. PMID: 39802674.
      View in: PubMed
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