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Christine Uta Heike Vohwinkel

TitleAssociate Professor
InstitutionUniversity of Colorado Denver - Anschutz Medical Campus
DepartmentSOM-PEDS
Phone303/724-8283

    Collapse Research 
    Collapse research activities and funding
    K08HL130586     (VOHWINKEL, CHRISTINE U)Jan 1, 2018 - Mar 15, 2022
    NIH
    Alveolar epithelial carbohydrate metabolism in acute lung injury
    Role: Principal Investigator

    Collapse Bibliographic 
    Collapse selected publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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    1. Vohwinkel CU, Tuder RM. Bronchopulmonary Dysplasia: Endothelial Cells in the Driver's Seat. Am J Respir Cell Mol Biol. 2021 Apr 15. PMID: 33856963.
      View in: PubMed
    2. Vohwinkel CU, Coit EJ, Burns N, Elajaili H, Hernandez-Saavedra D, Yuan X, Eckle T, Nozik E, Tuder RM, Eltzschig HK. Targeting alveolar-specific succinate dehydrogenase A attenuates pulmonary inflammation during acute lung injury. FASEB J. 2021 Apr; 35(4):e21468. PMID: 33687752.
      View in: PubMed
    3. Fredericks RM, Wang GS, Vohwinkel CU, Graham JK. An Unusual Case of Severe Anion Gap Metabolic Acidosis in a 3-year-old Girl. Pediatr Rev. 2021 Jan; 42(Suppl 1):S46-S51. PMID: 33386361.
      View in: PubMed
    4. Good RJ, Hernandez-Lagunas L, Allawzi A, Maltzahn JK, Vohwinkel CU, Upadhyay AK, Kompella UB, Birukov KG, Carpenter TC, Sucharov CC, Nozik-Grayck E. MicroRNA dysregulation in lung injury: the role of the miR-26a/EphA2 axis in regulation of endothelial permeability. . 2018 10 01; 315(4):L584-L594. PMID: 30024304.
      View in: PubMed
    5. Hoegl S, Burns N, Angulo M, Francis D, Osborne CM, Mills TW, Blackburn MR, Eltzschig HK, Vohwinkel CU. Capturing the multifactorial nature of ARDS - "Two-hit" approach to model murine acute lung injury. Physiol Rep. 2018 03; 6(6):e13648. PMID: 29595879.
      View in: PubMed
    6. Vohwinkel CU, Buchäckert Y, Al-Tamari HM, Mazzocchi LC, Eltzschig HK, Mayer K, Morty RE, Herold S, Seeger W, Pullamsetti SS, Vadász I. Restoration of Megalin-Mediated Clearance of Alveolar Protein as a Novel Therapeutic Approach for Acute Lung Injury. Am J Respir Cell Mol Biol. 2017 11; 57(5):589-602. PMID: 28678521.
      View in: PubMed
    7. Mazzocchi LC, Vohwinkel CU, Mayer K, Herold S, Morty RE, Seeger W, Vadász I. TGF-ß inhibits alveolar protein transport by promoting shedding, regulated intramembrane proteolysis, and transcriptional downregulation of megalin. . 2017 Nov 01; 313(5):L807-L824. PMID: 28705909.
      View in: PubMed
    8. Hoffman O, Burns N, Vadász I, Eltzschig HK, Edwards MG, Vohwinkel CU. Correction: Detrimental ELAVL-1/HuR-dependent GSK3ß mRNA stabilization impairs resolution in acute respiratory distress syndrome. PLoS One. 2017; 12(4):e0176134. PMID: 28407018.
      View in: PubMed
    9. Hoffman O, Burns N, Vadász I, Eltzschig HK, Edwards MG, Vohwinkel CU. Detrimental ELAVL-1/HuR-dependent GSK3ß mRNA stabilization impairs resolution in acute respiratory distress syndrome. PLoS One. 2017; 12(2):e0172116. PMID: 28196122.
      View in: PubMed
    10. McNamee EN, Vohwinkel C, Eltzschig HK. Hydroxylation-independent HIF-1a stabilization through PKA: A new paradigm for hypoxia signaling. Sci Signal. 2016 05 31; 9(430):fs11. PMID: 27245611.
      View in: PubMed
    11. Hoegl S, Zwissler B, Eltzschig HK, Vohwinkel C. Acute respiratory distress syndrome following cardiovascular surgery: current concepts and novel therapeutic approaches. Curr Opin Anaesthesiol. 2016 Feb; 29(1):94-100. PMID: 26598954.
      View in: PubMed
    12. Cao D, Maddux AB, Mashburn D, Vohwinkel C, Wang GS. Pediatric occult methanol intoxication with hyperammonemia. Am J Emerg Med. 2016 Feb; 34(2):343.e5-6. PMID: 26162618.
      View in: PubMed
    13. Vohwinkel CU, Hoegl S, Eltzschig HK. Hypoxia signaling during acute lung injury. J Appl Physiol (1985). 2015 Nov 15; 119(10):1157-63. PMID: 25977449.
      View in: PubMed
    14. Gates KL, Howell HA, Nair A, Vohwinkel CU, Welch LC, Beitel GJ, Hauser AR, Sznajder JI, Sporn PH. Hypercapnia impairs lung neutrophil function and increases mortality in murine pseudomonas pneumonia. Am J Respir Cell Mol Biol. 2013 Nov; 49(5):821-8. PMID: 23777386.
      View in: PubMed
    15. Grzesik BA, Vohwinkel CU, Morty RE, Mayer K, Herold S, Seeger W, Vadász I. Efficient gene delivery to primary alveolar epithelial cells by nucleofection. . 2013 Dec; 305(11):L786-94. PMID: 24077946.
      View in: PubMed
    16. Vohwinkel CU, Vadász I. Influenza A matrix protein M2 downregulates CFTR: inhibition of chloride transport by a proton channel of the viral envelope. . 2013 Jun 15; 304(12):L813-6. PMID: 23605001.
      View in: PubMed
    17. Buchäckert Y, Rummel S, Vohwinkel CU, Gabrielli NM, Grzesik BA, Mayer K, Herold S, Morty RE, Seeger W, Vadász I. Megalin mediates transepithelial albumin clearance from the alveolar space of intact rabbit lungs. J Physiol. 2012 Oct 15; 590(20):5167-81. PMID: 22826129.
      View in: PubMed
    18. Vohwinkel CU, Lecuona E, Sun H, Sommer N, Vadász I, Chandel NS, Sznajder JI. Elevated CO(2) levels cause mitochondrial dysfunction and impair cell proliferation. J Biol Chem. 2011 Oct 28; 286(43):37067-76. PMID: 21903582.
      View in: PubMed
    19. Lecuona E, Sun H, Vohwinkel C, Ciechanover A, Sznajder JI. Ubiquitination participates in the lysosomal degradation of Na,K-ATPase in steady-state conditions. Am J Respir Cell Mol Biol. 2009 Dec; 41(6):671-9. PMID: 19286978.
      View in: PubMed
    20. Haas D, Garbade SF, Vohwinkel C, Muschol N, Trefz FK, Penzien JM, Zschocke J, Hoffmann GF, Burgard P. Effects of cholesterol and simvastatin treatment in patients with Smith-Lemli-Opitz syndrome (SLOS). J Inherit Metab Dis. 2007 Jun; 30(3):375-87. PMID: 17497248.
      View in: PubMed
    21. Breitinger HG, Lanig H, Vohwinkel C, Grewer C, Breitinger U, Clark T, Becker CM. Molecular dynamics simulation links conformation of a pore-flanking region to hyperekplexia-related dysfunction of the inhibitory glycine receptor. Chem Biol. 2004 Oct; 11(10):1339-50. PMID: 15489161.
      View in: PubMed
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