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Christine Uta Heike Vohwinkel

TitleAsst Professor
InstitutionUniversity of Colorado Denver - Anschutz Medical Campus

    Collapse Research 
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    K08HL130586     (VOHWINKEL, CHRISTINE U)Jan 1, 2018 - Mar 15, 2022
    Alveolar epithelial carbohydrate metabolism in acute lung injury
    Role: Principal Investigator

    Collapse Bibliographic 
    Collapse selected publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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    1. Good RJ, Hernandez-Lagunas L, Allawzi A, Maltzahn JK, Vohwinkel CU, Upadhyay AK, Kompella UB, Birukov KG, Carpenter TC, Sucharov CC, Nozik-Grayck E. MicroRNA dysregulation in lung injury: the role of the miR-26a/EphA2 axis in regulation of endothelial permeability. Am J Physiol Lung Cell Mol Physiol. 2018 Oct 01; 315(4):L584-L594. PMID: 30024304.
      View in: PubMed
    2. Hoegl S, Burns N, Angulo M, Francis D, Osborne CM, Mills TW, Blackburn MR, Eltzschig HK, Vohwinkel CU. Capturing the multifactorial nature of ARDS - "Two-hit" approach to model murine acute lung injury. Physiol Rep. 2018 03; 6(6):e13648. PMID: 29595879.
      View in: PubMed
    3. Vohwinkel CU, Buchäckert Y, Al-Tamari HM, Mazzocchi LC, Eltzschig HK, Mayer K, Morty RE, Herold S, Seeger W, Pullamsetti SS, Vadász I. Restoration of Megalin-Mediated Clearance of Alveolar Protein as a Novel Therapeutic Approach for Acute Lung Injury. Am J Respir Cell Mol Biol. 2017 11; 57(5):589-602. PMID: 28678521.
      View in: PubMed
    4. Mazzocchi LC, Vohwinkel CU, Mayer K, Herold S, Morty RE, Seeger W, Vadász I. TGF-ß inhibits alveolar protein transport by promoting shedding, regulated intramembrane proteolysis, and transcriptional downregulation of megalin. Am J Physiol Lung Cell Mol Physiol. 2017 Nov 01; 313(5):L807-L824. PMID: 28705909.
      View in: PubMed
    5. Hoffman O, Burns N, Vadász I, Eltzschig HK, Edwards MG, Vohwinkel CU. Correction: Detrimental ELAVL-1/HuR-dependent GSK3ß mRNA stabilization impairs resolution in acute respiratory distress syndrome. PLoS One. 2017; 12(4):e0176134. PMID: 28407018.
      View in: PubMed
    6. Hoffman O, Burns N, Vadász I, Eltzschig HK, Edwards MG, Vohwinkel CU. Detrimental ELAVL-1/HuR-dependent GSK3ß mRNA stabilization impairs resolution in acute respiratory distress syndrome. PLoS One. 2017; 12(2):e0172116. PMID: 28196122.
      View in: PubMed
    7. McNamee EN, Vohwinkel C, Eltzschig HK. Hydroxylation-independent HIF-1a stabilization through PKA: A new paradigm for hypoxia signaling. Sci Signal. 2016 05 31; 9(430):fs11. PMID: 27245611.
      View in: PubMed
    8. Hoegl S, Zwissler B, Eltzschig HK, Vohwinkel C. Acute respiratory distress syndrome following cardiovascular surgery: current concepts and novel therapeutic approaches. Curr Opin Anaesthesiol. 2016 Feb; 29(1):94-100. PMID: 26598954; PMCID: PMC4689613.
    9. Cao D, Maddux AB, Mashburn D, Vohwinkel C, Wang GS. Pediatric occult methanol intoxication with hyperammonemia. Am J Emerg Med. 2016 Feb; 34(2):343.e5-6. PMID: 26162618.
      View in: PubMed
    10. Vohwinkel CU, Hoegl S, Eltzschig HK. Hypoxia signaling during acute lung injury. J Appl Physiol (1985). 2015 Nov 15; 119(10):1157-63. PMID: 25977449; PMCID: PMC4816417 [Available on 11/15/16].
    11. Gates KL, Howell HA, Nair A, Vohwinkel CU, Welch LC, Beitel GJ, Hauser AR, Sznajder JI, Sporn PH. Hypercapnia impairs lung neutrophil function and increases mortality in murine pseudomonas pneumonia. Am J Respir Cell Mol Biol. 2013 Nov; 49(5):821-8. PMID: 23777386; PMCID: PMC3931098.
    12. Grzesik BA, Vohwinkel CU, Morty RE, Mayer K, Herold S, Seeger W, Vadász I. Efficient gene delivery to primary alveolar epithelial cells by nucleofection. Am J Physiol Lung Cell Mol Physiol. 2013 Dec; 305(11):L786-94. PMID: 24077946.
      View in: PubMed
    13. Vohwinkel CU, Vadász I. Influenza A matrix protein M2 downregulates CFTR: inhibition of chloride transport by a proton channel of the viral envelope. Am J Physiol Lung Cell Mol Physiol. 2013 Jun 15; 304(12):L813-6. PMID: 23605001.
      View in: PubMed
    14. Buchäckert Y, Rummel S, Vohwinkel CU, Gabrielli NM, Grzesik BA, Mayer K, Herold S, Morty RE, Seeger W, Vadász I. Megalin mediates transepithelial albumin clearance from the alveolar space of intact rabbit lungs. J Physiol. 2012 Oct 15; 590(20):5167-81. PMID: 22826129; PMCID: PMC3497570.
    15. Vohwinkel CU, Lecuona E, Sun H, Sommer N, Vadász I, Chandel NS, Sznajder JI. Elevated CO(2) levels cause mitochondrial dysfunction and impair cell proliferation. J Biol Chem. 2011 Oct 28; 286(43):37067-76. PMID: 21903582; PMCID: PMC3199454.
    16. Lecuona E, Sun H, Vohwinkel C, Ciechanover A, Sznajder JI. Ubiquitination participates in the lysosomal degradation of Na,K-ATPase in steady-state conditions. Am J Respir Cell Mol Biol. 2009 Dec; 41(6):671-9. PMID: 19286978; PMCID: PMC2784405.
    17. Haas D, Garbade SF, Vohwinkel C, Muschol N, Trefz FK, Penzien JM, Zschocke J, Hoffmann GF, Burgard P. Effects of cholesterol and simvastatin treatment in patients with Smith-Lemli-Opitz syndrome (SLOS). J Inherit Metab Dis. 2007 Jun; 30(3):375-87. PMID: 17497248.
      View in: PubMed
    18. Breitinger HG, Lanig H, Vohwinkel C, Grewer C, Breitinger U, Clark T, Becker CM. Molecular dynamics simulation links conformation of a pore-flanking region to hyperekplexia-related dysfunction of the inhibitory glycine receptor. Chem Biol. 2004 Oct; 11(10):1339-50. PMID: 15489161.
      View in: PubMed
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