Colorado PROFILES, The Colorado Clinical and Translational Sciences Institute (CCTSI)
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Last Name
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Nicholas Anthony Alfonso

TitleAssistant Professor
InstitutionUniversity of Colorado Denver - Anschutz Medical Campus
DepartmentSOM-ORTHO General Operations
    Other Positions
    TitleDirector-Faculty
    InstitutionUniversity of Colorado Denver - Anschutz Medical Campus
    DepartmentSOM-ORTHO General Operations


    Collapse Bibliographic 
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    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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    1. O'Toole RV, O'Hara NN, Carlini AR, Schrank GM, Chung S, Gary JL, Obremskey W, Matuszewski PE, Teague D, Natoli RM, Gitajn IL, Weaver MJ, Renninger CH, Levack AE, Degani Y, Collins SC, Weston-Farber E, Howe AL, Thompson RE, Castillo RC, Karunakar MA, Blum L, Harmer L, Hsu JR, Kempton LB, Phelps KD, Seymour RB, Sims SH, Acharya MS, Callahan H, Chavez-Araujo LM, Churchill C, Gambuzza MP, Haim KR, Ishman E, Kendall JS, Mullis ND, Young C, Pilson HT, Carroll EA, Goodman JB, Holden MB, Jones AL, Moon C, Lin CA, Marecek GS, Moffitt GB, Conlan T, George AV, Fisher LA, Mullin DS, Recendez CL, Aneja A, Brameier DT, Heng M, Ly TV, Stenquist DS, Suneja N, Wignakumar T, Borgida JS, Policicchio TJ, Hanson GR, Alese OM, Ricci WM, Behrens SB, Dvorzhinskiy A, Bilodeau RE, Klinger CE, Mullis BH, Jang Y, Lopas LA, McKinley TO, O'Neill DC, Szatkowski JP, Virkus WW, Hill LC, Gaski G, Hymes RA, Ahn J, Goch AM, Holzman M, Malekzadeh AS, Schulman JE, Rivera JC, Krause PC, Bridgman C, Cohen J, Eikani C, Chavez M, Kudulis M, Warner SJ, Achor TS, Choo A, Eastman JG, Kellam PJ, Boutte SJ, Guevara KD, Reid KR, Vallier HA, Tucci AV, Davis JM, Bell AC, Bonyun ME, Healey K, Li V, McKibben NS, Nascone J, Okhuereigbe D, Sciadini MF, Slobogean G, Zingas N, Kovvur M, Lawrence JE, Phipps H, Rudnicki J, Turner KE, Hayda R, Evans AR, Quinnan S, Benitez A, Rehman S, Soderquist MC, Townsend CB, Caroom C, Collins AC, Okwumabua E, Shaikh HS, Spitler CA, Agarwal A, Johnson MD, Haller JM, Marchand LS, Alfonso NA, Gorman MA, Charlton WM, Scott BR, Kraus KM, Meredith SJ, Talwar S, Bergin PF, Jha AJ, McGee S, Nehete PV, Pryor TA, Spears I, Chen AT, Kelley B, Nez NR, Ertl WJ, Hull BR, Blumenthal S, Patterson JT, Flynn C, Ross RC, Agarwal A, Weiss DB, Hadeed MM, Yarboro SR, Daoud T, McVey ED, Whiting PS, Domes C, Goodspeed DC, Kuhn GR, Boyce R, Libos A, Mitchell PM, Moreno-Diaz AF, Ponce RB, Stinner DJ, Tatman LM, Velasco-Castro J, Trochez K, Satpathy J, Zuelzer DA, Potter BK. Intrawound Tobramycin Plus Vancomycin to Prevent Surgical Site Infection in Tibial Fractures: The TOBRA Randomized Clinical Trial. JAMA. 2026 May 12; 335(18):1586-1595. PMID: 41984450.
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    2. Krieg B, Epperson A, Scott T, Awad M, Rosa C, Gu S, Gorman M, Alfonso N. Patient reported cannabis use is associated with greater 24-hour postoperative opioid use but shorter length of stay in isolated tibial shaft fractures. Eur J Orthop Surg Traumatol. 2026 Mar 09; 36(1). PMID: 41801490.
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    3. Alfonso NA. Care Controversies: Isolated Anterior Fixation Is Best for Tile B, APC-2 Pelvic Ring Injuries. J Orthop Trauma. 2026 Mar 01; 40(3):137-138. PMID: 41118262.
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    4. Hop JC, Richman EH, Marchetti DC, Royster BW, Gorman MA, Alfonso NA. Surgical fixation of clavicle fractures in the elderly: utilization and compensation over two decades. Eur J Orthop Surg Traumatol. 2026 Jan 22; 36(1):85. PMID: 41569458.
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    5. Stoner AK, Pezzanite LM, Dow SW, Alfonso NA, McGilvray KC. An In Vitro Assessment of a Biopolymer-Based Medical Foam for Enhanced Antifibrinolytic and Infection Prophylaxis for Acute Wound Management. ACS Appl Bio Mater. 2025 Dec 15; 8(12):10878-10889. PMID: 41252298.
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    6. ElNemer W, Kishan A, Fox HM, Nelson S, Merkely GB, Alfonso NA, Paschos NK, Best MJ, Srikumaran U. Shortened length of stay and its impact on total shoulder arthroplasty expenses. Shoulder Elbow. 2026 Apr; 18(2):318-325. PMID: 40417406.
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    7. Sajid MI, Grayson W, John MP, Taylor S, Lauck BJ, Zaidi Z, Savage A, Griffin N, Awad M, Chen AT, Hwang J, Alfonso N, Mir HR. Efficacy of Topical Antibiotic Powder Application in the Emergency Department on Reducing Deep Fracture-Related Infection in Type III Open Lower Extremity Fractures: A Multicenter Study. J Am Acad Orthop Surg. 2025 Dec 15; 33(24):e1489-e1496. PMID: 40179368.
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    8. Epperson AB, Awad ME, Gorman M, Loker K, Alfonso NA, Stoneback JW. Clinical practice guidelines for antimicrobial-loaded cements and beads in orthopedic trauma and arthroplasty. Eur J Orthop Surg Traumatol. 2024 Nov 25; 35(1):25. PMID: 39585403.
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    9. Richman EH, Brinkman JC, Paul BR, Griffin N, Alfonso N. Trends in Medicare Utilization and Reimbursement for Intertrochanteric Femur Fractures: A 21-Year Review. Eur J Orthop Surg Traumatol. 2024 Nov 21; 35(1):13. PMID: 39567377.
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    10. Awad ME, Griffin NA, Epperson AB, Alfonso NA, Ou-Yang D. Extended Postoperative Antibiotic Prophylaxis Is Associated with No Clinical Value and Higher Projected Cost Following Adult Spinal Surgery: A Stratified Meta-Analysis and Probability-Based Cost Projections. JBJS Rev. 2024 Sep 01; 12(9). PMID: 39226392.
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    11. Krieg B, Dayton M, Alfonso N. Re-revision Extensor Mechanism Reconstruction Because of Nonunion and Tendon Failure After Total Knee Arthroplasty. Orthopedics. 2024 Sep-Oct; 47(5):e273-e276. PMID: 39163604.
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    12. Sinkler MA, Benedick A, Kavanagh M, Alfonso N, Vallier HA. Complications and Outcomes After Fixation of Lisfranc Injuries at an Urban Level 1 Trauma Center. J Orthop Trauma. 2024 05 01; 38(5):e169-e174. PMID: 38294227.
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    13. Abu-Shawareb H, Acree R, Adams P, Adams J, Addis B, Aden R, Adrian P, Afeyan BB, Aggleton M, Aghaian L, Aguirre A, Aikens D, Akre J, Albert F, Albrecht M, Albright BJ, Albritton J, Alcala J, Alday C, Alessi DA, Alexander N, Alfonso J, Alfonso N, Alger E, Ali SJ, Ali ZA, Allen A, Alley WE, Amala P, Amendt PA, Amick P, Ammula S, Amorin C, Ampleford DJ, Anderson RW, Anklam T, Antipa N, Appelbe B, Aracne-Ruddle C, Araya E, Archuleta TN, Arend M, Arnold P, Arnold T, Arsenlis A, Asay J, Atherton LJ, Atkinson D, Atkinson R, Auerbach JM, Austin B, Auyang L, Awwal AAS, Aybar N, Ayers J, Ayers S, Ayers T, Azevedo S, Bachmann B, Back CA, Bae J, Bailey DS, Bailey J, Baisden T, Baker KL, Baldis H, Barber D, Barberis M, Barker D, Barnes A, Barnes CW, Barrios MA, Barty C, Bass I, Batha SH, Baxamusa SH, Bazan G, Beagle JK, Beale R, Beck BR, Beck JB, Bedzyk M, Beeler RG, Beeler RG, Behrendt W, Belk L, Bell P, Belyaev M, Benage JF, Bennett G, Benedetti LR, Benedict LX, Berger RL, Bernat T, Bernstein LA, Berry B, Bertolini L, Besenbruch G, Betcher J, Bettenhausen R, Betti R, Bezzerides B, Bhandarkar SD, Bickel R, Biener J, Biesiada T, Bigelow K, Bigelow-Granillo J, Bigman V, Bionta RM, Birge NW, Bitter M, Black AC, Bleile R, Bleuel DL, Bliss E, Bliss E, Blue B, Boehly T, Boehm K, Boley CD, Bonanno R, Bond EJ, Bond T, Bonino MJ, Borden M, Bourgade JL, Bousquet J, Bowers J, Bowers M, Boyd R, Boyle D, Bozek A, Bradley DK, Bradley KS, Bradley PA, Bradley L, Brannon L, Brantley PS, Braun D, Braun T, Brienza-Larsen K, Briggs R, Briggs TM, Britten J, Brooks ED, Browning D, Bruhn MW, Brunner TA, Bruns H, Brunton G, Bryant B, Buczek T, Bude J, Buitano L, Burkhart S, Burmark J, Burnham A, Burr R, Busby LE, Butlin B, Cabeltis R, Cable M, Cabot WH, Cagadas B, Caggiano J, Cahayag R, Caldwell SE, Calkins S, Callahan DA, Calleja-Aguirre J, Camara L, Camp D, Campbell EM, Campbell JH, Carey B, Carey R, Carlisle K, Carlson L, Carman L, Carmichael J, Carpenter A, Carr C, Carrera JA, Casavant D, Casey A, Casey DT, Castillo A, Castillo E, Castor JI, Castro C, Caughey W, Cavitt R, Celeste J, Celliers PM, Cerjan C, Chandler G, Chang B, Chang C, Chang J, Chang L, Chapman R, Chapman TD, Chase L, Chen H, Chen H, Chen K, Chen LY, Cheng B, Chittenden J, Choate C, Chou J, Chrien RE, Chrisp M, Christensen K, Christensen M, Christiansen NS, Christopherson AR, Chung M, Church JA, Clark A, Clark DS, Clark K, Clark R, Claus L, Cline B, Cline JA, Cobble JA, Cochrane K, Cohen B, Cohen S, Collette MR, Collins GW, Collins LA, Collins TJB, Conder A, Conrad B, Conyers M, Cook AW, Cook D, Cook R, Cooley JC, Cooper G, Cope T, Copeland SR, Coppari F, Cortez J, Cox J, Crandall DH, Crane J, Craxton RS, Cray M, Crilly A, Crippen JW, Cross D, Cuneo M, Cuotts G, Czajka CE, Czechowicz D, Daly T, Danforth P, Danly C, Darbee R, Darlington B, Datte P, Dauffy L, Davalos G, Davidovits S, Davis P, Davis J, Dawson S, Day RD, Day TH, Dayton M, Deck C, Decker C, Deeney C, DeFriend KA, Deis G, Delamater ND, Delettrez JA, Demaret R, Demos S, Dempsey SM, Desjardin R, Desjardins T, Desjarlais MP, Dewald EL, DeYoreo J, Diaz S, Dimonte G, Dittrich TR, Divol L, Dixit SN, Dixon J, Do A, Dodd ES, Dolan D, Donovan A, Donovan M, Döppner T, Dorrer C, Dorsano N, Douglas MR, Dow D, Downie J, Downing E, Dozieres M, Draggoo V, Drake D, Drake RP, Drake T, Dreifuerst G, Drury O, DuBois DF, DuBois PF, Dunham G, Durocher M, Dylla-Spears R, Dymoke-Bradshaw AKL, Dzenitis B, Ebbers C, Eckart M, Eddinger S, Eder D, Edgell D, Edwards MJ, Efthimion P, Eggert JH, Ehrlich B, Ehrmann P, Elhadj S, Ellerbee C, Elliott NS, Ellison CL, Elsner F, Emerich M, Engelhorn K, England T, English E, Epperson P, Epstein R, Erbert G, Erickson MA, Erskine DJ, Erlandson A, Espinosa RJ, Estes C, Estabrook KG, Evans S, Fabyan A, Fair J, Fallejo R, Farmer N, Farmer WA, Farrell M, Fatherley VE, Fedorov M, Feigenbaum E, Fehrenbach T, Feit M, Felker B, Ferguson W, Fernandez JC, Fernandez-Panella A, Fess S, Field JE, Filip CV, Fincke JR, et al. Achievement of Target Gain Larger than Unity in an Inertial Fusion Experiment. Phys Rev Lett. 2024 Feb 09; 132(6):065102. PMID: 38394591.
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    14. Richman EH, Richman OT, Lee MS, Qubain L, Heylmun L, Awad ME, Alfonso N. Social Media and Digital Footprints in Orthopaedic Trauma: An Analysis of 1465 Orthopaedic Trauma Association Members. J Orthop Trauma. 2024 01 01; 38(1):e36. PMID: 37559214.
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    15. Awad ME, Chung JY, Griffin N, Stoneback JW, Alfonso NA. Prophylactic Intrawound Antibiotics Significantly Reduce the Risk of Deep Infections in Fracture Fixation: Subgroup Meta-analyses of the Type of Fracture, Antibiotics, and Organism. J Orthop Trauma. 2023 10 01; 37(10):e400-e409. PMID: 37296086.
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    16. Igumenshchev IV, Theobald W, Stoeckl C, Shah RC, Bishel DT, Goncharov VN, Bonino MJ, Campbell EM, Ceurvorst L, Chin DA, Collins TJB, Fess S, Harding DR, Sampat S, Shaffer NR, Shvydky A, Smith EA, Trickey WT, Waxer LJ, Colaïtis A, Liotard R, Adrian PJ, Atzeni S, Barbato F, Savino L, Alfonso N, Haid A, Do M. Proof-of-Principle Experiment on the Dynamic Shell Formation for Inertial Confinement Fusion. Phys Rev Lett. 2023 Jul 07; 131(1):015102. PMID: 37478441.
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    17. Belton M, Kelley N, Baldini T, Steward J, Alfonso N. Diagnosis of traumatic shoulder arthrotomies using saline load test with intra-articular pressure monitoring. Eur J Orthop Surg Traumatol. 2023 Jul; 33(5):2137-2142. PMID: 36269430.
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    18. Abu-Shawareb H, Acree R, Adams P, Adams J, Addis B, Aden R, Adrian P, Afeyan BB, Aggleton M, Aghaian L, Aguirre A, Aikens D, Akre J, Albert F, Albrecht M, Albright BJ, Albritton J, Alcala J, Alday C, Alessi DA, Alexander N, Alfonso J, Alfonso N, Alger E, Ali SJ, Ali ZA, Alley WE, Amala P, Amendt PA, Amick P, Ammula S, Amorin C, Ampleford DJ, Anderson RW, Anklam T, Antipa N, Appelbe B, Aracne-Ruddle C, Araya E, Arend M, Arnold P, Arnold T, Asay J, Atherton LJ, Atkinson D, Atkinson R, Auerbach JM, Austin B, Auyang L, Awwal AS, Ayers J, Ayers S, Ayers T, Azevedo S, Bachmann B, Back CA, Bae J, Bailey DS, Bailey J, Baisden T, Baker KL, Baldis H, Barber D, Barberis M, Barker D, Barnes A, Barnes CW, Barrios MA, Barty C, Bass I, Batha SH, Baxamusa SH, Bazan G, Beagle JK, Beale R, Beck BR, Beck JB, Bedzyk M, Beeler RG, Beeler RG, Behrendt W, Belk L, Bell P, Belyaev M, Benage JF, Bennett G, Benedetti LR, Benedict LX, Berger R, Bernat T, Bernstein LA, Berry B, Bertolini L, Besenbruch G, Betcher J, Bettenhausen R, Betti R, Bezzerides B, Bhandarkar SD, Bickel R, Biener J, Biesiada T, Bigelow K, Bigelow-Granillo J, Bigman V, Bionta RM, Birge NW, Bitter M, Black AC, Bleile R, Bleuel DL, Bliss E, Bliss E, Blue B, Boehly T, Boehm K, Boley CD, Bonanno R, Bond EJ, Bond T, Bonino MJ, Borden M, Bourgade JL, Bousquet J, Bowers J, Bowers M, Boyd R, Bozek A, Bradley DK, Bradley KS, Bradley PA, Bradley L, Brannon L, Brantley PS, Braun D, Braun T, Brienza-Larsen K, Briggs TM, Britten J, Brooks ED, Browning D, Bruhn MW, Brunner TA, Bruns H, Brunton G, Bryant B, Buczek T, Bude J, Buitano L, Burkhart S, Burmark J, Burnham A, Burr R, Busby LE, Butlin B, Cabeltis R, Cable M, Cabot WH, Cagadas B, Caggiano J, Cahayag R, Caldwell SE, Calkins S, Callahan DA, Calleja-Aguirre J, Camara L, Camp D, Campbell EM, Campbell JH, Carey B, Carey R, Carlisle K, Carlson L, Carman L, Carmichael J, Carpenter A, Carr C, Carrera JA, Casavant D, Casey A, Casey DT, Castillo A, Castillo E, Castor JI, Castro C, Caughey W, Cavitt R, Celeste J, Celliers PM, Cerjan C, Chandler G, Chang B, Chang C, Chang J, Chang L, Chapman R, Chapman T, Chase L, Chen H, Chen H, Chen K, Chen LY, Cheng B, Chittenden J, Choate C, Chou J, Chrien RE, Chrisp M, Christensen K, Christensen M, Christopherson AR, Chung M, Church JA, Clark A, Clark DS, Clark K, Clark R, Claus L, Cline B, Cline JA, Cobble JA, Cochrane K, Cohen B, Cohen S, Collette MR, Collins G, Collins LA, Collins TJB, Conder A, Conrad B, Conyers M, Cook AW, Cook D, Cook R, Cooley JC, Cooper G, Cope T, Copeland SR, Coppari F, Cortez J, Cox J, Crandall DH, Crane J, Craxton RS, Cray M, Crilly A, Crippen JW, Cross D, Cuneo M, Cuotts G, Czajka CE, Czechowicz D, Daly T, Danforth P, Darbee R, Darlington B, Datte P, Dauffy L, Davalos G, Davidovits S, Davis P, Davis J, Dawson S, Day RD, Day TH, Dayton M, Deck C, Decker C, Deeney C, DeFriend KA, Deis G, Delamater ND, Delettrez JA, Demaret R, Demos S, Dempsey SM, Desjardin R, Desjardins T, Desjarlais MP, Dewald EL, DeYoreo J, Diaz S, Dimonte G, Dittrich TR, Divol L, Dixit SN, Dixon J, Dodd ES, Dolan D, Donovan A, Donovan M, Döppner T, Dorrer C, Dorsano N, Douglas MR, Dow D, Downie J, Downing E, Dozieres M, Draggoo V, Drake D, Drake RP, Drake T, Dreifuerst G, DuBois DF, DuBois PF, Dunham G, Dylla-Spears R, Dymoke-Bradshaw AKL, Dzenitis B, Ebbers C, Eckart M, Eddinger S, Eder D, Edgell D, Edwards MJ, Efthimion P, Eggert JH, Ehrlich B, Ehrmann P, Elhadj S, Ellerbee C, Elliott NS, Ellison CL, Elsner F, Emerich M, Engelhorn K, England T, English E, Epperson P, Epstein R, Erbert G, Erickson MA, Erskine DJ, Erlandson A, Espinosa RJ, Estes C, Estabrook KG, Evans S, Fabyan A, Fair J, Fallejo R, Farmer N, Farmer WA, Farrell M, Fatherley VE, Fedorov M, Feigenbaum E, Feit M, Ferguson W, Fernandez JC, Fernandez-Panella A, Fess S, Field JE, Filip CV, Fincke JR, Finn T, Finnegan SM, Finucane RG, Fischer M, Fisher A, Fisher J, Fishler B, Fittinghoff D, Fitzsimmons P, Flegel M, Flippo KA, Florio J, Folta J, et al. Lawson Criterion for Ignition Exceeded in an Inertial Fusion Experiment. Phys Rev Lett. 2022 Aug 12; 129(7):075001. PMID: 36018710.
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    19. Flanagan CD, Joseph NM, Copp J, Romeo N, Alfonso N, Hirschfeld A. Weight-bearing status may influence rates of radiographic healing following reamed, intramedullary fixation of diaphyseal femur fractures. OTA Int. 2021 Dec; 4(4):e154. PMID: 34765904.
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    20. Moore AS, Meezan NB, Milovich J, Johnson S, Heredia R, Baumann TF, Biener M, Bhandarkar SD, Chen H, Divol L, Izumi N, Nikroo A, Baker K, Jones O, Landen OL, Hsing WW, Moody JD, Thomas CA, Lahmann B, Williams J, Alfonso N, Schoff ME. Foam-lined hohlraum, inertial confinement fusion experiments on the National Ignition Facility. Phys Rev E. 2020 Nov; 102(5-1):051201. PMID: 33327093.
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    21. Joseph NM, Alfonso N, Hirschfeld AG. Compartment syndrome following use of tissue plasminogen activator for frostbite in the setting of concomitant diaphyseal tibia fracture. OTA Int. 2020 Jun; 3(2):e079. PMID: 33937702.
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    22. Alfonso NA, Ryan W, Baldini T, Reiter M, Joyce C, Mauffrey C. Fixation of Transverse Acetabular Fractures With Precontoured Plates Alone Causes Fracture Malreduction: A Biomechanical Assessment. J Orthop Trauma. 2020 Feb; 34(2):89-94. PMID: 31567698.
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    23. Ryan W, Alfonso NA, Baldini T, Kumparatana P, Reiter M, Joyce C, Wei C, Zhang Y, Mauffrey C. Precontoured Quadrilateral Surface Acetabular Plate Fixation Demonstrates Increased Stability When Compared With Pelvic Reconstruction Plates: A Biomechanical Study. J Orthop Trauma. 2019 Sep; 33(9):e325-e330. PMID: 31436712.
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    24. Alfonso NA, Baldini T, Stahel PF. A New Fastener With Improved Bone-To-Implant Interface Shows Superior Torque Stripping Resistance Compared With the Standard Buttress Screw. J Orthop Trauma. 2019 Apr; 33(4):e137-e142. PMID: 30893221.
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    25. Stahel PF, Alfonso NA, Henderson C, Baldini T. Introducing the "Bone-Screw-Fastener" for improved screw fixation in orthopedic surgery: a revolutionary paradigm shift? Patient Saf Surg. 2017; 11:6. PMID: 28321265.
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    26. Diawara MM, Litt JS, Unis D, Alfonso N, Martinez L, Crock JG, Smith DB, Carsella J. Arsenic, cadmium, lead, and mercury in surface soils, Pueblo, Colorado: implications for population health risk. Environ Geochem Health. 2006 Aug; 28(4):297-315. PMID: 16752202.
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