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Edward L Melanson

TitleProfessor
InstitutionUniversity of Colorado Denver - Anschutz Medical Campus
DepartmentSOM-MED
    Other Positions
    TitleProfessor Adjunct
    InstitutionUniversity of Colorado Boulder
    DepartmentIntegrative Physiology


    Collapse Research 
    Collapse research activities and funding
    F32DK009961     (MELANSON, EDWARD L)Oct 1, 1999
    NIH/NIDDK
    INTERACTION FAT OXIDATION &ENERGY INTAKE WITH ACTIVITY
    Role: Principal Investigator
    K01DK061348     (MELANSON, EDWARD L)Mar 15, 2003 - Nov 30, 2008
    NIH/NIDDK
    Fat Metabolism During Exercise in Obesity
    Role: Principal Investigator
    R01DK077088     (MELANSON, EDWARD L)Sep 1, 2007 - Aug 31, 2012
    NIH/NIDDK
    Energy Expenditure &Activity During &After Exercise-Induced Weight Loss
    Role: Principal Investigator
    R01DK091287     (MELANSON, EDWARD L)Sep 21, 2011 - Aug 31, 2015
    NIH/NIDDK
    Measuring free-living energy expenditure using direct calorimetry
    Role: Principal Investigator
    R01DK112260     (MELANSON, EDWARD L)Sep 16, 2016 - Aug 31, 2019
    NIH/NIDDK
    The impact of estrogen status on the biological function of brown adipose tissue in women measured using quantitative PET/CT
    Role: Principal Investigator
    R21DK113401     (MELANSON, EDWARD L)May 1, 2017 - Apr 30, 2019
    NIH/NIDDK
    Rapid measurements of water isotopes in human breath and saliva for doubly labeled water analysis
    Role: Principal Investigator

    Collapse Bibliographic 
    Collapse selected publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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    1. Depner CM, Melanson EL, McHill AW, Wright KP. Mistimed food intake and sleep alters 24-hour time-of-day patterns of the human plasma proteome. Proc Natl Acad Sci U S A. 2018 Jun 05; 115(23):E5390-E5399. PMID: 29784788.
      View in: PubMed
    2. Melanson EL, Lyden K, Gibbons E, Gavin KM, Wolfe P, Wierman ME, Schwartz RS, Kohrt WM. Influence of Estradiol Status on Physical Activity in Premenopausal Women. Med Sci Sports Exerc. 2018 Mar 05. PMID: 29509642.
      View in: PubMed
    3. Schenkman M, Moore CG, Kohrt WM, Hall DA, Delitto A, Comella CL, Josbeno DA, Christiansen CL, Berman BD, Kluger BM, Melanson EL, Jain S, Robichaud JA, Poon C, Corcos DM. Effect of High-Intensity Treadmill Exercise on Motor Symptoms in Patients With De Novo Parkinson Disease: A Phase 2 Randomized Clinical Trial. JAMA Neurol. 2018 Feb 01; 75(2):219-226. PMID: 29228079.
      View in: PubMed
    4. Melanson EL, Ritchie HK, Dear TB, Catenacci V, Shea K, Connick E, Moehlman TM, Stothard ER, Higgins J, McHill AW, Wright KP. Daytime bright light exposure, metabolism, and individual differences in wake and sleep energy expenditure during circadian entrainment and misalignment. Neurobiol Sleep Circadian Rhythms. 2018 Jan; 4:49-56. PMID: 29876528.
      View in: PubMed
    5. Ostendorf DM, Lyden K, Pan Z, Wyatt HR, Hill JO, Melanson EL, Catenacci VA. Objectively Measured Physical Activity and Sedentary Behavior in Successful Weight Loss Maintainers. Obesity (Silver Spring). 2018 01; 26(1):53-60. PMID: 29090513.
      View in: PubMed
    6. Melanson EL, Swibas T, Kohrt WM, Catenacci VA, Creasy SA, Plasqui G, Wouters L, Speakman JR, Berman ESF. Validation of the doubly labeled water method using off-axis integrated cavity output spectroscopy and isotope ratio mass spectrometry. Am J Physiol Endocrinol Metab. 2018 02 01; 314(2):E124-E130. PMID: 28978547.
      View in: PubMed
    7. Hegde N, Bries M, Swibas T, Melanson E, Sazonov E. Automatic Recognition of Activities of Daily Living utilizing Insole Based and Wrist Worn Wearable Sensors. IEEE J Biomed Health Inform. 2017 Aug 01. PMID: 28783651.
      View in: PubMed
    8. Hegde N, Bries M, Melanson E, Sazonov E. One size fits all electronics for insole-based activity monitoring. Conf Proc IEEE Eng Med Biol Soc. 2017 07; 2017:3564-3567. PMID: 29060668.
      View in: PubMed
    9. Peterman JE, Wright KP, Melanson EL, Kram R, Byrnes WC. Motor-Driven (Passive) Cycling: A Potential Physical Inactivity Countermeasure? Med Sci Sports Exerc. 2016 09; 48(9):1821-8. PMID: 27054677; PMCID: PMC4987275 [Available on 09/01/17].
      View in: PubMed, PubMed Central
    10. Catenacci VA, Pan Z, Ostendorf D, Brannon S, Gozansky WS, Mattson MP, Martin B, MacLean PS, Melanson EL, Troy Donahoo W. A randomized pilot study comparing zero-calorie alternate-day fasting to daily caloric restriction in adults with obesity. Obesity (Silver Spring). 2016 09; 24(9):1874-83. PMID: 27569118.
      View in: PubMed
    11. Hegde N, Melanson E, Sazonov E. Development of a real time activity monitoring Android application utilizing SmartStep. Conf Proc IEEE Eng Med Biol Soc. 2016 08; 2016:1886-1889. PMID: 28268695.
      View in: PubMed
    12. Legget KT, Wylie KP, Cornier MA, Melanson EL, Paschall CJ, Tregellas JR. Exercise-related changes in between-network connectivity in overweight/obese adults. Physiol Behav. 2016 May 01; 158:60-7. PMID: 26921099; PMCID: PMC4803578 [Available on 05/01/17].
      View in: PubMed, PubMed Central
    13. Eckel RH, Depner CM, Perreault L, Markwald RR, Smith MR, McHill AW, Higgins J, Melanson EL, Wright KP. Morning Circadian Misalignment during Short Sleep Duration Impacts Insulin Sensitivity. Curr Biol. 2015 Nov 16; 25(22):3004-10. PMID: 26549253.
      View in: PubMed
    14. Shea KL, Gavin KM, Melanson EL, Gibbons E, Stavros A, Wolfe P, Kittelson JM, Vondracek SF, Schwartz RS, Wierman ME, Kohrt WM. Body composition and bone mineral density after ovarian hormone suppression with or without estradiol treatment. Menopause. 2015 Oct; 22(10):1045-52. PMID: 25783468; PMCID: PMC4760356 [Available on 10/01/16].
      View in: PubMed, PubMed Central
    15. Paxton RJ, Melanson EL, Stevens-Lapsley JE, Christiansen CL. Physical activity after total knee arthroplasty: A critical review. World J Orthop. 2015 Sep 18; 6(8):614-22. PMID: 26396937; PMCID: PMC4573505.
      View in: PubMed, PubMed Central
    16. Melanson EL, Gavin KM, Shea KL, Wolfe P, Wierman ME, Schwartz RS, Kohrt WM. Regulation of energy expenditure by estradiol in premenopausal women. J Appl Physiol (1985). 2015 Nov 01; 119(9):975-81. PMID: 26338457; PMCID: PMC4628992 [Available on 11/01/16].
      View in: PubMed, PubMed Central
    17. Sazonov E, Hegde N, Browning RC, Melanson EL, Sazonova NA. Posture and activity recognition and energy expenditure estimation in a wearable platform. IEEE J Biomed Health Inform. 2015 Jul; 19(4):1339-46. PMID: 26011870; PMCID: PMC4545967.
      View in: PubMed, PubMed Central
    18. McHill AW, Melanson EL, Higgins J, Connick E, Moehlman TM, Stothard ER, Wright KP. Impact of circadian misalignment on energy metabolism during simulated nightshift work. Proc Natl Acad Sci U S A. 2014 Dec 02; 111(48):17302-7. PMID: 25404342; PMCID: PMC4260578.
      View in: PubMed, PubMed Central
    19. Fontana JM, Higgins JA, Schuckers SC, Bellisle F, Pan Z, Melanson EL, Neuman MR, Sazonov E. Energy intake estimation from counts of chews and swallows. Appetite. 2015 Feb; 85:14-21. PMID: 25447016; PMCID: PMC4281480.
      View in: PubMed, PubMed Central
    20. Lyden K, Swibas T, Catenacci V, Guo R, Szuminsky N, Melanson EL. Estimating energy expenditure using heat flux measured at a single body site. Med Sci Sports Exerc. 2014 Nov; 46(11):2159-67. PMID: 24811326; PMCID: PMC4199907.
      View in: PubMed, PubMed Central
    21. Rudroff T, Holmes MR, Melanson EL, Kelsey MM. Sex differences in time to task failure during early pubertal development. Muscle Nerve. 2014 Jun; 49(6):887-94. PMID: 24037802.
      View in: PubMed
    22. Melanson E, Kozy Keadle S, Donnelly JE, Braun B, King NA. Response. Med Sci Sports Exerc. 2014 Feb; 46(2):424. PMID: 24435074; PMCID: PMC3908900.
      View in: PubMed, PubMed Central
    23. Sazonova N, Browning R, Melanson E, Sazonov E. Posture and activity recognition and energy expenditure prediction in a wearable platform. Conf Proc IEEE Eng Med Biol Soc. 2014; 2014:4163-7. PMID: 25570909.
      View in: PubMed
    24. Dannecker KL, Sazonova NA, Melanson EL, Sazonov ES, Browning RC. A comparison of energy expenditure estimation of several physical activity monitors. Med Sci Sports Exerc. 2013 Nov; 45(11):2105-12. PMID: 23669877; PMCID: PMC3800491.
      View in: PubMed, PubMed Central
    25. Sevits KJ, Melanson EL, Swibas T, Binns SE, Klochak AL, Lonac MC, Peltonen GL, Scalzo RL, Schweder MM, Smith AM, Wood LM, Melby CL, Bell C. Total daily energy expenditure is increased following a single bout of sprint interval training. Physiol Rep. 2013 Oct; 1(5):e00131. PMID: 24303194; PMCID: PMC3841058.
      View in: PubMed, PubMed Central
    26. McFadden KL, Cornier MA, Melanson EL, Bechtell JL, Tregellas JR. Effects of exercise on resting-state default mode and salience network activity in overweight/obese adults. Neuroreport. 2013 Oct 23; 24(15):866-71. PMID: 24022176; PMCID: PMC3937986.
      View in: PubMed, PubMed Central
    27. Melanson EL, Keadle SK, Donnelly JE, Braun B, King NA. Resistance to exercise-induced weight loss: compensatory behavioral adaptations. Med Sci Sports Exerc. 2013 Aug; 45(8):1600-9. PMID: 23470300; PMCID: PMC3696411.
      View in: PubMed, PubMed Central
    28. Markwald RR, Melanson EL, Smith MR, Higgins J, Perreault L, Eckel RH, Wright KP. Impact of insufficient sleep on total daily energy expenditure, food intake, and weight gain. Proc Natl Acad Sci U S A. 2013 Apr 02; 110(14):5695-700. PMID: 23479616; PMCID: PMC3619301.
      View in: PubMed, PubMed Central
    29. Rudroff T, Kelsey MM, Melanson EL, McQueen MB, Enoka RM. Associations between neuromuscular function and levels of physical activity differ for boys and girls during puberty. J Pediatr. 2013 Aug; 163(2):349-54. PMID: 23415611.
      View in: PubMed
    30. Ohkawara K, Cornier MA, Kohrt WM, Melanson EL. Effects of increased meal frequency on fat oxidation and perceived hunger. Obesity (Silver Spring). 2013 Feb; 21(2):336-43. PMID: 23404961; PMCID: PMC4391809.
      View in: PubMed, PubMed Central
    31. Minor BD, Heusinger DE, Melanson EL, Hamilton KL, Miller BF. Energy balance changes the anabolic effect of postexercise feeding in older individuals. J Gerontol A Biol Sci Med Sci. 2012 Nov; 67(11):1161-9. PMID: 22459620; PMCID: PMC3668386.
      View in: PubMed, PubMed Central
    32. Bergouignan A, Gozansky WS, Barry DW, Leitner W, MacLean PS, Hill JO, Draznin B, Melanson EL. Increasing dietary fat elicits similar changes in fat oxidation and markers of muscle oxidative capacity in lean and obese humans. PLoS One. 2012; 7(1):e30164. PMID: 22253914; PMCID: PMC3257254.
      View in: PubMed, PubMed Central
    33. Cornier MA, Melanson EL, Salzberg AK, Bechtell JL, Tregellas JR. The effects of exercise on the neuronal response to food cues. Physiol Behav. 2012 Feb 28; 105(4):1028-34. PMID: 22155218; PMCID: PMC3260391.
      View in: PubMed, PubMed Central
    34. Steig AJ, Jackman MR, Giles ED, Higgins JA, Johnson GC, Mahan C, Melanson EL, Wyatt HR, Eckel RH, Hill JO, MacLean PS. Exercise reduces appetite and traffics excess nutrients away from energetically efficient pathways of lipid deposition during the early stages of weight regain. Am J Physiol Regul Integr Comp Physiol. 2011 Sep; 301(3):R656-67. PMID: 21715696; PMCID: PMC3174759.
      View in: PubMed, PubMed Central
    35. Jung CM, Melanson EL, Frydendall EJ, Perreault L, Eckel RH, Wright KP. Energy expenditure during sleep, sleep deprivation and sleep following sleep deprivation in adult humans. J Physiol. 2011 Jan 01; 589(Pt 1):235-44. PMID: 21059762; PMCID: PMC3039272.
      View in: PubMed, PubMed Central
    36. Jordan LY, Melanson EL, Melby CL, Hickey MS, Miller BF. Nitrogen balance in older individuals in energy balance depends on timing of protein intake. J Gerontol A Biol Sci Med Sci. 2010 Oct; 65(10):1068-76. PMID: 20622139; PMCID: PMC3031452.
      View in: PubMed, PubMed Central
    37. Lopez-Meyer P, Makeyev O, Schuckers S, Melanson EL, Neuman MR, Sazonov E. Detection of food intake from swallowing sequences by supervised and unsupervised methods. Ann Biomed Eng. 2010 Aug; 38(8):2766-74. PMID: 20352335; PMCID: PMC2901415.
      View in: PubMed, PubMed Central
    38. Melanson EL, Ingebrigtsen JP, Bergouignan A, Ohkawara K, Kohrt WM, Lighton JR. A new approach for flow-through respirometry measurements in humans. Am J Physiol Regul Integr Comp Physiol. 2010 Jun; 298(6):R1571-9. PMID: 20200135; PMCID: PMC2886696.
      View in: PubMed, PubMed Central
    39. Melanson EL, Gozansky WS, Barry DW, Maclean PS, Grunwald GK, Hill JO. When energy balance is maintained, exercise does not induce negative fat balance in lean sedentary, obese sedentary, or lean endurance-trained individuals. J Appl Physiol (1985). 2009 Dec; 107(6):1847-56. PMID: 19833807; PMCID: PMC3774345.
      View in: PubMed, PubMed Central
    40. Sazonov ES, Makeyev O, Schuckers S, Lopez-Meyer P, Melanson EL, Neuman MR. Automatic detection of swallowing events by acoustical means for applications of monitoring of ingestive behavior. IEEE Trans Biomed Eng. 2010 Mar; 57(3):626-33. PMID: 19789095; PMCID: PMC2886152.
      View in: PubMed, PubMed Central
    41. Melanson EL, Astrup A, Donahoo WT. The relationship between dietary fat and fatty acid intake and body weight, diabetes, and the metabolic syndrome. Ann Nutr Metab. 2009; 55(1-3):229-43. PMID: 19752544.
      View in: PubMed
    42. MacLean PS, Higgins JA, Wyatt HR, Melanson EL, Johnson GC, Jackman MR, Giles ED, Brown IE, Hill JO. Regular exercise attenuates the metabolic drive to regain weight after long-term weight loss. Am J Physiol Regul Integr Comp Physiol. 2009 Sep; 297(3):R793-802. PMID: 19587114; PMCID: PMC2739786.
      View in: PubMed, PubMed Central
    43. Sazonov ES, Schuckers SA, Lopez-Meyer P, Makeyev O, Melanson EL, Neuman MR, Hill JO. Toward objective monitoring of ingestive behavior in free-living population. Obesity (Silver Spring). 2009 Oct; 17(10):1971-5. PMID: 19444225; PMCID: PMC2865137.
      View in: PubMed, PubMed Central
    44. Melanson EL, MacLean PS, Hill JO. Exercise improves fat metabolism in muscle but does not increase 24-h fat oxidation. Exerc Sport Sci Rev. 2009 Apr; 37(2):93-101. PMID: 19305201; PMCID: PMC2885974.
      View in: PubMed, PubMed Central
    45. Volpe SL, Melanson EL, Kline G. Validation of bioelectrical impedance analysis to hydrostatic weighing in male body builders. Acta Diabetol. 2010 Mar; 47(1):55-8. PMID: 19219400.
      View in: PubMed
    46. Melanson EL, Dykstra JC, Szuminsky N. A novel approach for measuring energy expenditure in free-living humans. Conf Proc IEEE Eng Med Biol Soc. 2009; 2009:6873-7. PMID: 19964187.
      View in: PubMed
    47. Sazonov E, Schuckers S, Lopez-Meyer P, Makeyev O, Sazonova N, Melanson EL, Neuman M. Non-invasive monitoring of chewing and swallowing for objective quantification of ingestive behavior. Physiol Meas. 2008 May; 29(5):525-41. PMID: 18427161; PMCID: PMC2582220.
      View in: PubMed, PubMed Central
    48. Melanson EL, Donahoo WT, Grunwald GK, Schwartz R. Changes in 24-h substrate oxidation in older and younger men in response to exercise. J Appl Physiol (1985). 2007 Nov; 103(5):1576-82. PMID: 17717111.
      View in: PubMed
    49. MacLean PS, Higgins JA, Jackman MR, Johnson GC, Fleming-Elder BK, Wyatt HR, Melanson EL, Hill JO. Peripheral metabolic responses to prolonged weight reduction that promote rapid, efficient regain in obesity-prone rats. Am J Physiol Regul Integr Comp Physiol. 2006 Jun; 290(6):R1577-88. PMID: 16455763.
      View in: PubMed
    50. Melanson EL, Donahoo WT, Dong F, Ida T, Zemel MB. Effect of low- and high-calcium dairy-based diets on macronutrient oxidation in humans. Obes Res. 2005 Dec; 13(12):2102-12. PMID: 16421344.
      View in: PubMed
    51. Krantz MJ, Donahoo WT, Melanson EL, Mehler PS. QT interval dispersion and resting metabolic rate in chronic anorexia nervosa. Int J Eat Disord. 2005 Mar; 37(2):166-70. PMID: 15732074.
      View in: PubMed
    52. Melanson EL, Sharp TA, Seagle HM, Donahoo WT, Grunwald GK, Peters JC, Hamilton JT, Hill JO. Twenty-four-hour metabolic responses to resistance exercise in women. J Strength Cond Res. 2005 Feb; 19(1):61-6. PMID: 15705046.
      View in: PubMed
    53. Donahoo WT, Levine JA, Melanson EL. Variability in energy expenditure and its components. Curr Opin Clin Nutr Metab Care. 2004 Nov; 7(6):599-605. PMID: 15534426.
      View in: PubMed
    54. Melanson EL, Donahoo WT, Krantz MJ, Poirier P, Mehler PS. Resting and ambulatory heart rate variability in chronic anorexia nervosa. Am J Cardiol. 2004 Nov 01; 94(9):1217-20. PMID: 15518630.
      View in: PubMed
    55. MacLean PS, Higgins JA, Johnson GC, Fleming-Elder BK, Donahoo WT, Melanson EL, Hill JO. Enhanced metabolic efficiency contributes to weight regain after weight loss in obesity-prone rats. Am J Physiol Regul Integr Comp Physiol. 2004 Dec; 287(6):R1306-15. PMID: 15331386.
      View in: PubMed
    56. Melanson EL, Knoll JR, Bell ML, Donahoo WT, Hill JO, Nysse LJ, Lanningham-Foster L, Peters JC, Levine JA. Commercially available pedometers: considerations for accurate step counting. Prev Med. 2004 Aug; 39(2):361-8. PMID: 15226047.
      View in: PubMed
    57. Haugen HA, Melanson EL, Tran ZV, Kearney JT, Hill JO. Variability of measured resting metabolic rate. Am J Clin Nutr. 2003 Dec; 78(6):1141-5. PMID: 14668276.
      View in: PubMed
    58. Grunwald GK, Melanson EL, Forster JE, Seagle HM, Sharp TA, Hill JO. Comparison of methods for achieving 24-hour energy balance in a whole-room indirect calorimeter. Obes Res. 2003 Jun; 11(6):752-9. PMID: 12805396.
      View in: PubMed
    59. Melanson EL, Sharp TA, Seagle HM, Donahoo WT, Grunwald GK, Peters JC, Hamilton JT, Hill JO. Resistance and aerobic exercise have similar effects on 24-h nutrient oxidation. Med Sci Sports Exerc. 2002 Nov; 34(11):1793-800. PMID: 12439085.
      View in: PubMed
    60. Melanson EL, Sharp TA, Seagle HM, Horton TJ, Donahoo WT, Grunwald GK, Hamilton JT, Hill JO. Effect of exercise intensity on 24-h energy expenditure and nutrient oxidation. J Appl Physiol (1985). 2002 Mar; 92(3):1045-52. PMID: 11842038.
      View in: PubMed
    61. Melanson EL, Freedson PS. Validity of the Computer Science and Applications, Inc. (CSA) activity monitor. Med Sci Sports Exerc. 1995 Jun; 27(6):934-40. PMID: 7658958.
      View in: PubMed
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