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Irene E Schauer

TitleClinical Professor
InstitutionUniversity of Colorado Denver - Anschutz Medical Campus
DepartmentSOM-MED
Phone303/724-2879

    Collapse Research 
    Collapse research activities and funding
    K23DK091553     (SCHAUER, IRENE E)Aug 1, 2011 - Jul 31, 2015
    NIH
    Effect of Metformin on Vascular and Mitochondrial Function in Type 1 Diabetes
    Role: Principal Investigator
    F32HD006773     (SCHAUER, IRENE E)Apr 25, 1986
    NIH
    CHARACTERIZATION OF C ELEGANS GERM LINE SPECIFIC FACTOR
    Role: Principal Investigator

    Collapse Bibliographic 
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    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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    1. Gottlieb D, Abushamat LA, Nadeau KJ, Regensteiner JG, Reusch JEB, Tommerdahl KL, Rice J, Knaub LA, Monaco CMF, Hawke TJ, Perry CGR, Cree MG, Schauer IE. Muscle mitochondrial function is impaired in adults with type 1 diabetes. J Diabetes Complications. 2024 Aug; 38(8):108798. PMID: 38991492.
      View in: PubMed
    2. Jakicic JM, Kohrt WM, Houmard JA, Miller ME, Radom-Aizik S, Rasmussen BB, Ravussin E, Serra M, Stowe CL, Trappe S, Abouassi H, Adkins JN, Alekel DL, Ashley E, Bamman MM, Bergman BC, Bessesen DH, Broskey NT, Buford TW, Burant CF, Chen H, Christle JW, Clish CB, Coen PM, Collier D, Collins KA, Cooper DM, Cortes T, Cutter GR, Dubis G, Fern?ndez FM, Firnhaber J, Forman DE, Gaul DA, Gay N, Gerszten RE, Goodpaster BH, Gritsenko MA, Haddad F, Huffman KM, Ilkayeva O, Jankowski CM, Jin C, Johannsen NM, Johnson J, Kelly L, Kershaw E, Kraus WE, Laughlin M, Lester B, Lindholm ME, Lowe A, Lu CJ, McGowan J, Melanson EL, Montgomery S, Moore SG, Moreau KL, Muehlbauer M, Musi N, Nair VD, Newgard CB, Newman AB, Nicklas B, Nindl BC, Ormond K, Piehowski PD, Qian WJ, Rankinen T, Rejeski WJ, Robbins J, Rogers RJ, Rooney JL, Rushing S, Sanford JA, Schauer IE, Schwartz RS, Sealfon SC, Slentz C, Sloan R, Smith KS, Snyder M, Spahn J, Sparks LM, Stefanovic-Racic M, Tanner CJ, Thalacker-Mercer A, Tracy R, Trappe TA, Volpi E, Walsh MJ, Wheeler MT, Willis L. Molecular Transducers of Physical Activity Consortium (MoTrPAC): human studies design and protocol. J Appl Physiol (1985). 2024 Sep 01; 137(3):473-493. PMID: 38634503.
      View in: PubMed
    3. Simon SL, Snell-Bergeon JK, Sch?fer M, Barker AJ, Browne LP, Truong U, Tell SS, Vigers T, Baumgartner AD, Lyon E, Polsky S, Schauer IE, Nadeau KJ. Sleep duration and association with cardiometabolic health in adolescents and adults with type 1 diabetes: Results from the BCQR-T1D study. Diabetes Obes Metab. 2024 Jul; 26(7):2662-2672. PMID: 38584515.
      View in: PubMed
    4. Blondin DP, Haman F, Swibas TM, Hogan-Lamarre S, Dumont L, Guertin J, Richard G, Weissenburger Q, Hildreth KL, Schauer I, Panter S, Wyland L, Carpentier AC, Miao Y, Shi J, Juarez-Colunga E, Kohrt WM, Melanson EL. Brown adipose tissue metabolism in women is dependent on ovarian status. Am J Physiol Endocrinol Metab. 2024 May 01; 326(5):E588-E601. PMID: 38477875.
      View in: PubMed
    5. Abushamat LA, Schauer IE, Low Wang CC, Mitchell S, Herlache L, Bridenstine M, Durbin R, Snell-Bergeon JK, Regensteiner JG, Reusch JE. Rosiglitazone improves insulin resistance but does not improve exercise capacity in individuals with impaired glucose tolerance: A randomized clinical study. J Investig Med. 2024 03; 72(3):294-304. PMID: 38148342.
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    6. Santoro N, Kuhn K, Pretzel S, Schauer IE, Fought A, D'Alessandro A, Stephenson D, Bradford AP. A high-fat eucaloric diet induces reprometabolic syndrome of obesity in normal weight women. PNAS Nexus. 2024 Jan; 3(1):pgad440. PMID: 38178979.
      View in: PubMed
    7. Abushamat LA, Enge D, Fujiwara T, Sch?fer M, Clark EW, Englund EK, Scalzo RL, Johnston A, Rafferty D, Schauer IE, Whipple MO, Hunter K, Huebschmann AG, Nadeau KJ, Jarvis K, Barker AJ, Regensteiner JG, Reusch JEB. Obesity dominates early effects on cardiac structure and arterial stiffness in people with type 2 diabetes. J Hypertens. 2023 11 01; 41(11):1775-1784. PMID: 37589719.
      View in: PubMed
    8. Sch?fer M, Browne LP, Truong U, Bjornstad P, Tell S, Snell-Bergeon J, Baumgartner A, Hunter KS, Reusch JEB, Barker AJ, Nadeau KJ, Schauer IE. Bromocriptine Improves Central Aortic Stiffness in Adolescents With Type 1 Diabetes: Arterial Health Results From the BCQR-T1D Study. Hypertension. 2023 02; 80(2):482-491. PMID: 36472197.
      View in: PubMed
    9. Whipple MO, Pinto AJ, Abushamat LA, Bergouignan A, Chapman K, Huebschmann AG, Masters KS, Nadeau KJ, Scalzo RL, Schauer IE, Rafferty D, Reusch JEB, Regensteiner JG. Sex Differences in Physical Activity Among Individuals With Type 2 Diabetes Across the Life Span: A Systematic Review and Meta-analysis. Diabetes Care. 2022 09 01; 45(9):2163-2177. PMID: 36044665.
      View in: PubMed
    10. Tell SS, Schafer M, Vigers T, Baumgartner AD, Lyon E, Gross S, Polsky S, Snell-Bergeon JK, Schauer IE, Nadeau KJ. Bromocriptine quick-release as adjunct therapy in youth and adults with type 1 diabetes: A randomized, placebo-controlled crossover study. Diabetes Obes Metab. 2022 11; 24(11):2148-2158. PMID: 35712800.
      View in: PubMed
    11. McDonald R, Kuhn K, Nguyen TB, Tannous A, Schauer I, Santoro N, Bradford AP. A randomized clinical trial demonstrating cell type specific effects of hyperlipidemia and hyperinsulinemia on pituitary function. PLoS One. 2022; 17(5):e0268323. PMID: 35544473.
      View in: PubMed
    12. Kohn SA, Fought AJ, Kuhn K, Jones Slogett K, Bradford AP, Santoro N, Schauer I. Heparin Effects on Serum Gonadotropins. J Endocr Soc. 2022 Jan 01; 6(1):bvab178. PMID: 35024539.
      View in: PubMed
    13. Santoro N, Schauer IE, Kuhn K, Fought AJ, Babcock-Gilbert S, Bradford AP. Gonadotropin response to insulin and lipid infusion reproduces the reprometabolic syndrome of obesity in eumenorrheic lean women: a randomized crossover trial. Fertil Steril. 2021 08; 116(2):566-574. PMID: 33838870.
      View in: PubMed
    14. Tannous A, Bradford AP, Kuhn K, Fought A, Schauer I, Santoro N. A randomised trial examining inflammatory signaling in acutely induced hyperinsulinemia and hyperlipidemia in normal weight women-the reprometabolic syndrome. PLoS One. 2021; 16(3):e0247638. PMID: 33764994.
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    15. Scalzo RL, Schauer IE, Rafferty D, Knaub LA, Kvaratskhelia N, Johnson TK, Pott GB, Abushamat LA, Whipple MO, Huebschmann AG, Cree-Green M, Reusch JEB, Regensteiner JG. Single-leg exercise training augments in vivo skeletal muscle oxidative flux and vascular content and function in adults with type 2 diabetes. J Physiol. 2022 02; 600(4):963-978. PMID: 33569797.
      View in: PubMed
    16. Sherk VD, Schauer I, Shah VN. Update on the Acute Effects of Glucose, Insulin, and Incretins on Bone Turnover In Vivo. Curr Osteoporos Rep. 2020 08; 18(4):371-377. PMID: 32504189.
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    17. Abushamat LA, McClatchey PM, Scalzo RL, Schauer I, Huebschmann AG, Nadeau KJ, Liu Z, Regensteiner JG, Reusch JEB. Mechanistic Causes of Reduced Cardiorespiratory Fitness in Type 2 Diabetes. J Endocr Soc. 2020 Jul 01; 4(7):bvaa063. PMID: 32666009.
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    18. Scalzo RL, Rafferty D, Schauer I, Huebschmann AG, Cree-Green M, Reusch JEB, Regensteiner JG. Sitagliptin improves diastolic cardiac function but not cardiorespiratory fitness in adults with type 2 diabetes. J Diabetes Complications. 2019 08; 33(8):561-566. PMID: 31182338.
      View in: PubMed
    19. Cree-Green M, Scalzo RL, Harrall K, Newcomer BR, Schauer IE, Huebschmann AG, McMillin S, Brown MS, Orlicky D, Knaub L, Nadeau KJ, McClatchey PM, Bauer TA, Regensteiner JG, Reusch JEB. Supplemental Oxygen Improves In Vivo Mitochondrial Oxidative Phosphorylation Flux in Sedentary Obese Adults With Type 2 Diabetes. Diabetes. 2018 07; 67(7):1369-1379. PMID: 29643061.
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    20. Millstein RJ, Pyle LL, Bergman BC, Eckel RH, Maahs DM, Rewers MJ, Schauer IE, Snell-Bergeon JK. Sex-specific differences in insulin resistance in type 1 diabetes: The CACTI cohort. J Diabetes Complications. 2018 04; 32(4):418-423. PMID: 29449137.
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    21. Shah VN, Sippl R, Joshee P, Pyle L, Kohrt WM, Schauer IE, Snell-Bergeon JK. Trabecular bone quality is lower in adults with type 1 diabetes and is negatively associated with insulin resistance. Osteoporos Int. 2018 03; 29(3):733-739. PMID: 29290026.
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    22. Alman AC, Smith SR, Eckel RH, Hokanson JE, Burkhardt BR, Sudini PR, Wu Y, Schauer IE, Pereira RI, Snell-Bergeon JK. The ratio of pericardial to subcutaneous adipose tissues is associated with insulin resistance. Obesity (Silver Spring). 2017 07; 25(7):1284-1291. PMID: 28558132.
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    23. Mason McClatchey P, Bauer TA, Regensteiner JG, Schauer IE, Huebschmann AG, Reusch JEB. Dissociation of local and global skeletal muscle oxygen transport metrics in type 2 diabetes. J Diabetes Complications. 2017 Aug; 31(8):1311-1317. PMID: 28571935.
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    24. Chosich J, Bradford AP, Allshouse AA, Reusch JE, Santoro N, Schauer IE. Acute recapitulation of the hyperinsulinemia and hyperlipidemia characteristic of metabolic syndrome suppresses gonadotropins. Obesity (Silver Spring). 2017 03; 25(3):553-560. PMID: 28158916.
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    25. Duca LM, Maahs DM, Schauer IE, Bergman BC, Nadeau KJ, Bjornstad P, Rewers M, Snell-Bergeon JK. Development and Validation of a Method to Estimate Insulin Sensitivity in Patients With and Without Type 1 Diabetes. J Clin Endocrinol Metab. 2016 Feb; 101(2):686-95. PMID: 26672636.
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    26. Geary K, Knaub LA, Schauer IE, Keller AC, Watson PA, Miller MW, Garat CV, Nadeau KJ, Cree-Green M, Pugazhenthi S, Regensteiner JG, Klemm DJ, Reusch JE. Targeting mitochondria to restore failed adaptation to exercise in diabetes. Biochem Soc Trans. 2014 Apr; 42(2):231-8. PMID: 24646223.
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    27. Bergman BC, Howard D, Schauer IE, Maahs DM, Snell-Bergeon JK, Clement TW, Eckel RH, Perreault L, Rewers M. The importance of palmitoleic acid to adipocyte insulin resistance and whole-body insulin sensitivity in type 1 diabetes. J Clin Endocrinol Metab. 2013 Jan; 98(1):E40-50. PMID: 23150678.
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    28. Bergman BC, Howard D, Schauer IE, Maahs DM, Snell-Bergeon JK, Eckel RH, Perreault L, Rewers M. Features of hepatic and skeletal muscle insulin resistance unique to type 1 diabetes. J Clin Endocrinol Metab. 2012 May; 97(5):1663-72. PMID: 22362823.
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    29. Pereira RI, Snell-Bergeon JK, Erickson C, Schauer IE, Bergman BC, Rewers M, Maahs DM. Adiponectin dysregulation and insulin resistance in type 1 diabetes. J Clin Endocrinol Metab. 2012 Apr; 97(4):E642-7. PMID: 22278421.
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    30. Lobo IE, Loeb DF, Ghushchyan V, Schauer IE, Huebschmann AG. Missed opportunities for providing low-fat dietary advice to people with diabetes. Prev Chronic Dis. 2012; 9:E161. PMID: 23116780.
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    31. Maahs DM, Nadeau K, Snell-Bergeon JK, Schauer I, Bergman B, West NA, Rewers M, Daniels SR, Ogden LG, Hamman RF, Dabelea D. Association of insulin sensitivity to lipids across the lifespan in people with Type 1 diabetes. Diabet Med. 2011 Feb; 28(2):148-55. PMID: 21219421.
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    32. Snell-Bergeon JK, Roman R, Rodbard D, Garg S, Maahs DM, Schauer IE, Bergman BC, Kinney GL, Rewers M. Glycaemic variability is associated with coronary artery calcium in men with Type 1 diabetes: the Coronary Artery Calcification in Type 1 Diabetes study. Diabet Med. 2010 Dec; 27(12):1436-42. PMID: 21059097.
      View in: PubMed
    33. Schauer IE, Snell-Bergeon JK, Bergman BC, Maahs DM, Kretowski A, Eckel RH, Rewers M. Insulin resistance, defective insulin-mediated fatty acid suppression, and coronary artery calcification in subjects with and without type 1 diabetes: The CACTI study. Diabetes. 2011 Jan; 60(1):306-14. PMID: 20978091.
      View in: PubMed
    34. Maahs DM, Hokanson JE, Wang H, Kinney GL, Snell-Bergeon JK, East A, Bergman BC, Schauer IE, Rewers M, Eckel RH. Lipoprotein subfraction cholesterol distribution is proatherogenic in women with type 1 diabetes and insulin resistance. Diabetes. 2010 Jul; 59(7):1771-9. PMID: 20393149.
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    35. Schauer IE, Knaub LA, Lloyd M, Watson PA, Gliwa C, Lewis KE, Chait A, Klemm DJ, Gunter JM, Bouchard R, McDonald TO, O'Brien KD, Reusch JE. CREB downregulation in vascular disease: a common response to cardiovascular risk. Arterioscler Thromb Vasc Biol. 2010 Apr; 30(4):733-41. PMID: 20150559.
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    36. Schauer IE, Reusch JE. Nonesterified fatty acid exposure activates protective and mitogenic pathways in vascular smooth muscle cells by alternate signaling pathways. Metabolism. 2009 Mar; 58(3):319-27. PMID: 19217446.
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    37. Mamay CL, Schauer IE, Rice PL, McDoniels-Silvers A, Dwyer-Nield LD, You M, Sclafani RA, Malkinson AM. Cyclin D1 as a proliferative marker regulating retinoblastoma phosphorylation in mouse lung epithelial cells. Cancer Lett. 2001 Jul 26; 168(2):165-72. PMID: 11403921.
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    38. Shellman YG, Schauer IE, Oshiro G, Dohrmann P, Sclafani RA. Oligomers of the Cdc7/Dbf4 protein kinase exist in the yeast cell. Mol Gen Genet. 1998 Sep; 259(4):429-36. PMID: 9790600.
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    39. Groshong SD, Owen GI, Grimison B, Schauer IE, Todd MC, Langan TA, Sclafani RA, Lange CA, Horwitz KB. Biphasic regulation of breast cancer cell growth by progesterone: role of the cyclin-dependent kinase inhibitors, p21 and p27(Kip1). Mol Endocrinol. 1997 Oct; 11(11):1593-607. PMID: 9328342.
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    40. Sclafani RA, Schauer IE. Cell cycle control and cancer: lessons from lung cancer. J Investig Dermatol Symp Proc. 1996 Apr; 1(2):123-7. PMID: 9627705.
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    41. Schauer IE, Siriwardana S, Langan TA, Sclafani RA. Cyclin D1 overexpression vs. retinoblastoma inactivation: implications for growth control evasion in non-small cell and small cell lung cancer. Proc Natl Acad Sci U S A. 1994 Aug 02; 91(16):7827-31. PMID: 8052667.
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    42. Schauer IE, Wood WB. Early C. elegans embryos are transcriptionally active. Development. 1990 Dec; 110(4):1303-17. PMID: 2100265.
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    43. Schauer UJ, Schauer I. [Lipoprotein metabolism and beta receptor blockers]. Z Gesamte Inn Med. 1987 Apr 15; 42(8):201-5. PMID: 2888241.
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    44. Schauer UJ, Schauer I, Hummel S, Thielmann K. Inhibition of lecithin: cholesterol acyl transfer by propranolol treatment in man. Biomed Biochim Acta. 1985; 44(5):685-93. PMID: 4062915.
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    45. Schauer UJ, Schauer I, R?hling K, Thielmann K. Stimulation of lecithin:cholesterol acyl transfer by intravenous injection of heparin. Biomed Biochim Acta. 1984; 43(10):1165-72. PMID: 6525190.
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    46. Holtz H, Heinrich J, D?ck KD, R?hling K, Heller R, Schauer I. [Effectiveness of different intervention measures in children and adolescents with hypertension and lipid metabolism disorders]. Z Gesamte Inn Med. 1983 Dec 01; 38(23):644-9. PMID: 6670341.
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    47. Thielmann K, R?hling K, Schauer I, Leonhardt I, Herzberg V. Use of the microanalytical system KAPA for serial determinations of triglycerides, total cholesterol and HDL cholesterol in capillary plasma. Clin Chim Acta. 1981 Sep; 115(3):297-309. PMID: 7296876.
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    48. Schauer I, Schauer U, R?hling K, Thielmann K. The effect of propranolol treatment on total cholesterol, HDL cholesterol, triglycerides. Postheparin lipolytic activity and lecithin:cholesterol acyltransferase in hypertensive individuals. Artery. 1980; 8(2):146-50. PMID: 7458680.
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    49. Heinrich J, Knappe J, Gr?fner L, Holtz H, R?hling K, Schauer I, D?ck KD, Strube G. [The correlation of blood pressure, cholesterol and triglyceride concentration with the administration of hormonal contraceptives in women from 2 Erfurt large-scale plants]. Z Gesamte Inn Med. 1979 Sep 15; 34(18):540-4. PMID: 516840.
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