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Kevin B. Messacar

TitleAsst Professor
InstitutionUniversity of Colorado Denver - Anschutz Medical Campus
DepartmentSOM-PEDS

    Collapse Biography 
    Collapse awards and honors
    2017Gary Way Award for Outstanding Teaching by a Faculty Member, University of Colorado School of Medicine, Department of Pediatrics
    2015 - 2016Research Scholars Award, Children's Hospital Colorado Research Institute
    2014Astute Clinican Award, Colorado Department of Public Health and Environment
    2013Fellow Teaching Award, University of Colorado School of Medicine, Department of Pediatrics
    2011Resident Teaching Award, University of Colorado School of Medicine
    2011Outstanding Resident of the Year, University of Colorado Hospital Neonatal Care Unit
    2009Outstanding Intern of the Year, University of Colorado Hospital Neonatal Care Unit

    Collapse Overview 
    Collapse overview
    I am a pediatric infectious disease physician and researcher focused on improving diagnostic tests for infectious diseases and better understanding central nervous system infections, such as meningitis, encephalitis, and acute flaccid myelitis.


    Collapse Research 
    Collapse research activities and funding
    K23AI128069     (MESSACAR, KEVIN BRETT)Dec 12, 2016 - Nov 30, 2021
    NIH/NIAID
    Implementation and Effectiveness of a Rapid Cerebrospinal Fluid Diagnostics Program for Children with Suspected Central Nervous System Infection
    Role: Principal Investigator

    Collapse Bibliographic 
    Collapse selected publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
    List All   |   Timeline
    1. Martin JA, Messacar K, Yang ML, Maloney JA, Lindwall J, Carry T, Kenyon P, Sillau SH, Oleszek J, Tyler KL, Dominguez SR, Schreiner TL. Outcomes of Colorado children with acute flaccid myelitis at 1 year. Neurology. 2017 Jun 14. PMID: 28615421.
      View in: PubMed
    2. Messacar K, Campbell K, Pearce K, Pyle L, Hurst AL, Child J, Parker SK. A Handshake From Antimicrobial Stewardship Opens Doors for Infectious Disease Consultations. Clin Infect Dis. 2017 May 15; 64(10):1449-1452. PMID: 28186533.
      View in: PubMed
    3. Messacar K, Robinson CC, Pretty K, Yuan J, Dominguez SR. Surveillance for enterovirus D68 in colorado children reveals continued circulation. J Clin Virol. 2017 Jul; 92:39-41. PMID: 28521212.
      View in: PubMed
    4. Messacar K, Parker SK, Todd JK, Dominguez SR. Implementation of Rapid Molecular Infectious Disease Diagnostics: the Role of Diagnostic and Antimicrobial Stewardship. J Clin Microbiol. 2017 Mar; 55(3):715-723. PMID: 28031432.
      View in: PubMed
    5. Rao S, Messacar K, Torok MR, Rick AM, Holzberg J, Montano A, Bagdure D, Curtis DJ, Oberste MS, Nix WA, de Masellis G, Robinson CC, Dominguez SR. Enterovirus D68 in Critically Ill Children: A Comparison With Pandemic H1N1 Influenza. Pediatr Crit Care Med. 2016 Nov; 17(11):1023-1031. PMID: 27505715.
      View in: PubMed
    6. Messacar K, Hurst AL, Child J, Campbell K, Palmer C, Hamilton S, Dowell E, Robinson CC, Parker SK, Dominguez SR. Clinical Impact and Provider Acceptability of Real-Time Antimicrobial Stewardship Decision Support for Rapid Diagnostics in Children With Positive Blood Culture Results. J Pediatric Infect Dis Soc. 2016 Aug 19. PMID: 27543412.
      View in: PubMed
    7. Phan TG, Messacar K, Dominguez SR, da Costa AC, Deng X, Delwart E. A new densovirus in cerebrospinal fluid from a case of anti-NMDA-receptor encephalitis. Arch Virol. 2016 Nov; 161(11):3231-5. PMID: 27522586.
      View in: PubMed
    8. Messacar K, Schreiner TL, Van Haren K, Yang M, Glaser CA, Tyler KL, Dominguez SR. Acute flaccid myelitis: A clinical review of US cases 2012-2015. Ann Neurol. 2016 Sep; 80(3):326-38. PMID: 27422805.
      View in: PubMed
    9. Aliabadi N, Messacar K, Pastula DM, Robinson CC, Leshem E, Sejvar JJ, Nix WA, Oberste MS, Feikin DR, Dominguez SR. Enterovirus D68 Infection in Children with Acute Flaccid Myelitis, Colorado, USA, 2014. Emerg Infect Dis. 2016 Aug; 22(8):1387-94. PMID: 27434186; PMCID: PMC4982171.
    10. White A, Olson D, Messacar K. A state-wide assessment of the association between epidural analgesia, maternal fever and neonatal antibiotics in Colorado, 2007-2012. Arch Dis Child Fetal Neonatal Ed. 2017 Mar; 102(2):F120-F125. PMID: 27343198.
      View in: PubMed
    11. Messacar K, Breazeale G, Robinson CC, Dominguez SR. Potential clinical impact of the film array meningitis encephalitis panel in children with suspected central nervous system infections. Diagn Microbiol Infect Dis. 2016 Sep; 86(1):118-20. PMID: 27342782; PMCID: PMC4993637 [Available on 09/01/17].
    12. Bagdure D, Custer JW, Rao S, Messacar K, Dominguez S, Beam BW, Bhutta A. Hospitalized Children With Encephalitis in the United States: A Pediatric Health Information System Database Study. Pediatr Neurol. 2016 Aug; 61:58-62. PMID: 27353693.
      View in: PubMed
    13. Messacar K, Hawkins SM, Baker J, Pearce K, Tong S, Dominguez SR, Parker S. Resource Burden During the 2014 Enterovirus D68 Respiratory Disease Outbreak at Children's Hospital Colorado: An Unexpected Strain. JAMA Pediatr. 2016 Mar; 170(3):294-7. PMID: 26783716.
      View in: PubMed
    14. Greninger AL, Messacar K, Dunnebacke T, Naccache SN, Federman S, Bouquet J, Mirsky D, Nomura Y, Yagi S, Glaser C, Vollmer M, Press CA, Kleinschmidt-DeMasters BK, Dominguez SR, Chiu CY. Erratum to: Clinical metagenomic identification of Balamuthia mandrillaris encephalitis and assembly of the draft genome: the continuing case for reference genome sequencing. Genome Med. 2016 Jan 11; 8(1):1. PMID: 26750923; PMCID: PMC4707724.
    15. Good RJ, Messacar K, Stence NV, Press CA, Carpenter TC. Abnormal Neuroimaging in a Case of Infant Botulism. Front Pediatr. 2015; 3:108. PMID: 26697417; PMCID: PMC4676149.
    16. Greninger AL, Messacar K, Dunnebacke T, Naccache SN, Federman S, Bouquet J, Mirsky D, Nomura Y, Yagi S, Glaser C, Vollmer M, Press CA, Kleinschmidt-DeMasters BK, Klenschmidt-DeMasters BK, Dominguez SR, Chiu CY. Clinical metagenomic identification of Balamuthia mandrillaris encephalitis and assembly of the draft genome: the continuing case for reference genome sequencing. Genome Med. 2015 Dec 01; 7:113. PMID: 26620704; PMCID: PMC4665321.
    17. Messacar K, Abzug MJ, Dominguez SR. 2014 outbreak of enterovirus D68 in North America. J Med Virol. 2016 May; 88(5):739-45. PMID: 26489019.
      View in: PubMed
    18. Greninger AL, Naccache SN, Messacar K, Clayton A, Yu G, Somasekar S, Federman S, Stryke D, Anderson C, Yagi S, Messenger S, Wadford D, Xia D, Watt JP, Van Haren K, Dominguez SR, Glaser C, Aldrovandi G, Chiu CY. A novel outbreak enterovirus D68 strain associated with acute flaccid myelitis cases in the USA (2012-14): a retrospective cohort study. Lancet Infect Dis. 2015 Jun; 15(6):671-82. PMID: 25837569.
      View in: PubMed
    19. Messacar K, Breazeale G, Wei Q, Robinson CC, Dominguez SR. Epidemiology and clinical characteristics of infants with human parechovirus or human herpes virus-6 detected in cerebrospinal fluid tested for enterovirus or herpes simplex virus. J Med Virol. 2015 May; 87(5):829-35. PMID: 25650069.
      View in: PubMed
    20. Messacar K, Schreiner TL, Maloney JA, Wallace A, Ludke J, Oberste MS, Nix WA, Robinson CC, Glodé MP, Abzug MJ, Dominguez SR. A cluster of acute flaccid paralysis and cranial nerve dysfunction temporally associated with an outbreak of enterovirus D68 in children in Colorado, USA. Lancet. 2015 Apr 25; 385(9978):1662-71. PMID: 25638662.
      View in: PubMed
    21. Maloney JA, Mirsky DM, Messacar K, Dominguez SR, Schreiner T, Stence NV. MRI findings in children with acute flaccid paralysis and cranial nerve dysfunction occurring during the 2014 enterovirus D68 outbreak. AJNR Am J Neuroradiol. 2015 Feb; 36(2):245-50. PMID: 25414005.
      View in: PubMed
    22. Pastula DM, Aliabadi N, Haynes AK, Messacar K, Schreiner T, Maloney J, Dominguez SR, Davizon ES, Leshem E, Fischer M, Nix WA, Oberste MS, Seward J, Feikin D, Miller L. Acute neurologic illness of unknown etiology in children - Colorado, August-September 2014. MMWR Morb Mortal Wkly Rep. 2014 Oct 10; 63(40):901-2. PMID: 25299607.
      View in: PubMed
    23. Gaensbauer JT, Lindsey NP, Messacar K, Staples JE, Fischer M. Neuroinvasive arboviral disease in the United States: 2003 to 2012. Pediatrics. 2014 Sep; 134(3):e642-50. PMID: 25113294.
      View in: PubMed
    24. LaGreca J, Hotchkiss M, Carry P, Messacar K, Nyquist AC, Erickson M, Garg S. Bacteriology and Risk Factors for Development of Late (Greater Than One Year) Deep Infection Following Spinal Fusion With Instrumentation. Spine Deform. 2014 May; 2(3):186-190. PMID: 27927416.
      View in: PubMed
    25. Messacar K, Dunn J, Dominguez,SR, Khan T, McFarland EJ. Diffuse Nodular Lung Infiltrates in a Three-Year-Old Boy with Recurrent Sinopulmonary Infections and Parotitis. Journal of the Pediatric Infectious Disease Society. 2014.
    26. Messacar K, Dunn J, Khan TZ, Etcheverry A, McFarland EJ, Dominguez SR. Diffuse Nodular Lung Infiltrates in a Well Appearing Three-Year-Old Boy With Recurrent Sinopulmonary Infections and Parotitis. J Pediatric Infect Dis Soc. 2015 Mar; 4(1):74-7. PMID: 26407362.
      View in: PubMed
    27. Messacar K, Cree-Green M, Lovell M, Anderson MS, Dominguez SR. Severe Neuroinvasive West Nile Virus Infection in a Child with Undiagnosed Addison's Disease. IDCases. 2014; 1(3):29-31. PMID: 25133095.
      View in: PubMed
    28. Bacteriology and Risk Factors for Development of Late (Greater Than One Year) Deep Infection Following Spinal Fusion Instrumentation. One Year) Deep Infection Following Spinal Fusion With Instrumentation. Spine Deformity. 2013; 3(2):186-90.
    29. Messacar K, Robinson CC, Bagdure D, Curtis DJ, Glodé MP, Dominguez SR. Rhino/enteroviruses in hospitalized children: a comparison to influenza viruses. J Clin Virol. 2013 Jan; 56(1):41-5. PMID: 23078869; PMCID: PMC3529827.
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