Colorado PROFILES, The Colorado Clinical and Translational Sciences Institute (CCTSI)
Keywords
Last Name
Institution

Contact Us
If you have any questions or feedback please contact us.

Steven M Anderson

TitleProfessor
InstitutionUniversity of Colorado Denver - Anschutz Medical Campus
DepartmentSOM-Pathology
Phone303/724-3742

    Collapse Research 
    Collapse research activities and funding
    R29CA045241     (ANDERSON, STEVEN M)Aug 1, 1987 - Jul 31, 1992
    NIH/NCI
    MODULATION OF HEMATOPOIETIC STEM CELL PROLIFERATION
    Role: Principal Investigator

    R01CA045241     (ANDERSON, STEVEN M)Aug 1, 1987 - Jul 31, 2000
    NIH/NCI
    MODULATION OF HEMATOPOIETIC STEM CELL PROLIFERATION
    Role: Principal Investigator

    R01DK048879     (ANDERSON, STEVEN M)Sep 30, 1994 - Aug 31, 1997
    NIH/NIDDK
    ACTIVATION OF JAK2 TYROSINE KINASE IN BREAST CANCER
    Role: Principal Investigator

    R01GM055754     (ANDERSON, STEVEN M)Mar 1, 1998 - Feb 28, 2003
    NIH/NIGMS
    SRC-LIKE KINASES IN INTERLEUKIN-3 RECEPTOR SIGNALING
    Role: Principal Investigator

    R01DK053858     (ANDERSON, STEVEN M)Jun 1, 1998 - May 31, 2003
    NIH/NIDDK
    SIGNAL TRANSDUCTION BY THE PROLACTIN RECEPTOR
    Role: Principal Investigator

    R01CA085736     (ANDERSON, STEVEN M)Mar 10, 2000 - Feb 28, 2005
    NIH/NCI
    INDUCTION OF MAMMARY CANCER BY SIGNALING MOLECULES
    Role: Principal Investigator

    T35HL007961     (FLORES, SONIA CASTRO)Jun 1, 2000 - May 31, 2011
    NIH/NHLBI
    Biomedical Research Internship Program for Undergraduate
    Role: Co-Principal Investigator

    P01HD038129     (ANDERSON, STEVEN M)Aug 23, 2000 - Jul 31, 2016
    NIH/NICHD
    Functional Development of the Mammary Gland
    Role: Principal Investigator

    F33CA093037     (ANDERSON, STEVEN M)Sep 1, 2001
    NIH/NCI
    Identification of Substrates and Genes Regulated by Akt
    Role: Principal Investigator

    R01DK063674     (ANDERSON, STEVEN M)Jul 1, 2003 - Apr 30, 2007
    NIH/NIDDK
    Regulation of Akt and glucose transport by prolactin
    Role: Principal Investigator

    R01DE016354     (ANDERSON, STEVEN M)Jul 7, 2006 - Apr 30, 2011
    NIH/NIDCR
    Salivary Acinar Cell Apoptosis: Regulation of p53 by Akt
    Role: Principal Investigator

    R13CA128408     (ANDERSON, STEVEN M)May 1, 2007 - Apr 30, 2010
    NIH/NCI
    MAMMARY GLAND BIOLOGY GRC
    Role: Principal Investigator

    T36GM095349     (KIM, ALISON M)Mar 1, 2011 - Feb 29, 2016
    NIH/NIGMS
    Endocrine Network for Undergraduate Research and Carrier Development Opportunitie
    Role: Co-Principal Investigator

    R01CA138482     (ANDERSON, STEVEN M)Sep 15, 2011 - Jul 31, 2014
    NIH/NCI
    Is GLUT1 required for tumor growth and the Warburg Effect?
    Role: Principal Investigator

    Collapse Bibliographic 
    Collapse selected publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
    List All   |   Timeline
    1. Wellberg EA, Checkley LA, Giles ED, Johnson SJ, Oljira R, Wahdan-Alaswad R, Foright RM, Dooley G, Edgerton SM, Jindal S, Johnson GC, Richer JK, Kabos P, Thor AD, Schedin P, MacLean PS, Anderson SM. The Androgen Receptor Supports Tumor Progression After the Loss of Ovarian Function in a Preclinical Model of Obesity and Breast Cancer. Horm Cancer. 2017 Dec; 8(5-6):269-285. PMID: 28741260.
      View in: PubMed
    2. Checkley LA, Rudolph MC, Wellberg EA, Giles ED, Wahdan-Alaswad RS, Houck JA, Edgerton SM, Thor AD, Schedin P, Anderson SM, MacLean PS. Metformin Accumulation Correlates with Organic Cation Transporter 2 Protein Expression and Predicts Mammary Tumor Regression In Vivo. Cancer Prev Res (Phila). 2017 Mar; 10(3):198-207. PMID: 28154203.
      View in: PubMed
    3. Wellberg EA, Johnson S, Finlay-Schultz J, Lewis AS, Terrell KL, Sartorius CA, Abel ED, Muller WJ, Anderson SM. The glucose transporter GLUT1 is required for ErbB2-induced mammary tumorigenesis. Breast Cancer Res. 2016 Dec 20; 18(1):131. PMID: 27998284.
      View in: PubMed
    4. Heinz RE, Rudolph MC, Ramanathan P, Spoelstra NS, Butterfield KT, Webb PG, Babbs BL, Gao H, Chen S, Gordon MA, Anderson SM, Neville MC, Gu H, Richer JK. Constitutive expression of microRNA-150 in mammary epithelium suppresses secretory activation and impairs de novo lipogenesis. Development. 2016 Nov 15; 143(22):4236-4248. PMID: 27729410.
      View in: PubMed
    5. Wellberg EA, Rudolph MC, Lewis AS, Padilla-Just N, Jedlicka P, Anderson SM. Modulation of tumor fatty acids, through overexpression or loss of thyroid hormone responsive protein spot 14 is associated with altered growth and metastasis. Breast Cancer Res. 2014 Dec 04; 16(6):481. PMID: 25472762; PMCID: PMC4303195.
    6. Wahdan-Alaswad RS, Cochrane DR, Spoelstra NS, Howe EN, Edgerton SM, Anderson SM, Thor AD, Richer JK. Metformin-induced killing of triple-negative breast cancer cells is mediated by reduction in fatty acid synthase via miRNA-193b. Horm Cancer. 2014 Dec; 5(6):374-89. PMID: 25213330; PMCID: PMC4570735.
    7. Wellberg EA, Anderson SM. FASNating targets of metformin in breast cancer stem-like cells. Horm Cancer. 2014 Dec; 5(6):358-62. PMID: 25172609.
      View in: PubMed
    8. Rudolph MC, Wellberg EA, Lewis AS, Terrell KL, Merz AL, Maluf NK, Serkova NJ, Anderson SM. Thyroid hormone responsive protein Spot14 enhances catalysis of fatty acid synthase in lactating mammary epithelium. J Lipid Res. 2014 Jun; 55(6):1052-65. PMID: 24771867; PMCID: PMC4031937.
    9. Wie SM, Adwan TS, DeGregori J, Anderson SM, Reyland ME. Inhibiting tyrosine phosphorylation of protein kinase Cd (PKCd) protects the salivary gland from radiation damage. J Biol Chem. 2014 Apr 11; 289(15):10900-8. PMID: 24569990; PMCID: PMC4036201.
    10. Schmidt JW, Wehde BL, Sakamoto K, Triplett AA, Anderson SM, Tsichlis PN, Leone G, Wagner KU. Stat5 regulates the phosphatidylinositol 3-kinase/Akt1 pathway during mammary gland development and tumorigenesis. Mol Cell Biol. 2014 Apr; 34(7):1363-77. PMID: 24469394; PMCID: PMC3993568.
    11. Wahdan-Alaswad R, Fan Z, Edgerton SM, Liu B, Deng XS, Arnadottir SS, Richer JK, Anderson SM, Thor AD. Glucose promotes breast cancer aggression and reduces metformin efficacy. Cell Cycle. 2013 Dec 15; 12(24):3759-69. PMID: 24107633; PMCID: PMC3905068.
    12. Pereira RO, Wende AR, Olsen C, Soto J, Rawlings T, Zhu Y, Anderson SM, Abel ED. Inducible overexpression of GLUT1 prevents mitochondrial dysfunction and attenuates structural remodeling in pressure overload but does not prevent left ventricular dysfunction. J Am Heart Assoc. 2013 Sep 19; 2(5):e000301. PMID: 24052497; PMCID: PMC3835233.
    13. Neville MC, Webb P, Ramanathan P, Mannino MP, Pecorini C, Monks J, Anderson SM, MacLean P. The insulin receptor plays an important role in secretory differentiation in the mammary gland. Am J Physiol Endocrinol Metab. 2013 Nov 01; 305(9):E1103-14. PMID: 23982156; PMCID: PMC3840206.
    14. Giles ED, Wellberg EA, Astling DP, Anderson SM, Thor AD, Jindal S, Tan AC, Schedin PS, Maclean PS. Obesity and overfeeding affecting both tumor and systemic metabolism activates the progesterone receptor to contribute to postmenopausal breast cancer. Cancer Res. 2012 Dec 15; 72(24):6490-501. PMID: 23222299; PMCID: PMC4010325.
    15. Neville MC, Anderson SM, McManaman JL, Badger TM, Bunik M, Contractor N, Crume T, Dabelea D, Donovan SM, Forman N, Frank DN, Friedman JE, German JB, Goldman A, Hadsell D, Hambidge M, Hinde K, Horseman ND, Hovey RC, Janoff E, Krebs NF, Lebrilla CB, Lemay DG, MacLean PS, Meier P, Morrow AL, Neu J, Nommsen-Rivers LA, Raiten DJ, Rijnkels M, Seewaldt V, Shur BD, VanHouten J, Williamson P. Lactation and neonatal nutrition: defining and refining the critical questions. J Mammary Gland Biol Neoplasia. 2012 Jun; 17(2):167-88. PMID: 22752723; PMCID: PMC3428522.
    16. Rudolph MC, Karl Maluf N, Wellberg EA, Johnson CA, Murphy RC, Anderson SM. Mammalian fatty acid synthase activity from crude tissue lysates tracing ¹³C-labeled substrates using gas chromatography-mass spectrometry. Anal Biochem. 2012 Sep 15; 428(2):158-66. PMID: 22728958; PMCID: PMC3415257.
    17. Young CD, Lewis AS, Rudolph MC, Ruehle MD, Jackman MR, Yun UJ, Ilkun O, Pereira R, Abel ED, Anderson SM. Modulation of glucose transporter 1 (GLUT1) expression levels alters mouse mammary tumor cell growth in vitro and in vivo. PLoS One. 2011; 6(8):e23205. PMID: 21826239; PMCID: PMC3149640.
    18. Yuan T, Wang Y, Pao L, Anderson SM, Gu H. Lactation defect in a widely used MMTV-Cre transgenic line of mice. PLoS One. 2011 Apr 29; 6(4):e19233. PMID: 21559430; PMCID: PMC3084790.
    19. Rudolph MC, Russell TD, Webb P, Neville MC, Anderson SM. Prolactin-mediated regulation of lipid biosynthesis genes in vivo in the lactating mammary epithelial cell. Am J Physiol Endocrinol Metab. 2011 Jun; 300(6):E1059-68. PMID: 21467304; PMCID: PMC3118595.
    20. Rudolph MC, Monks J, Burns V, Phistry M, Marians R, Foote MR, Bauman DE, Anderson SM, Neville MC. Sterol regulatory element binding protein and dietary lipid regulation of fatty acid synthesis in the mammary epithelium. Am J Physiol Endocrinol Metab. 2010 Dec; 299(6):E918-27. PMID: 20739508; PMCID: PMC3006251.
    21. García-Martínez JM, Calcabrini A, González L, Martín-Forero E, Agulló-Ortuño MT, Simon V, Watkin H, Anderson SM, Roche S, Martín-Pérez J. A non-catalytic function of the Src family tyrosine kinases controls prolactin-induced Jak2 signaling. Cell Signal. 2010 Mar; 22(3):415-26. PMID: 19892015.
      View in: PubMed
    22. Nelson AC, Lyons TR, Young CD, Hansen KC, Anderson SM, Holt JT. AKT regulates BRCA1 stability in response to hormone signaling. Mol Cell Endocrinol. 2010 May 05; 319(1-2):129-42. PMID: 20085797; PMCID: PMC4548798.
    23. Rudolph MC, Wellberg EA, Anderson SM. Adipose-depleted mammary epithelial cells and organoids. J Mammary Gland Biol Neoplasia. 2009 Dec; 14(4):381-6. PMID: 19953310; PMCID: PMC4132965.
    24. Young CD, Anderson SM. Rah, rah, ROS: metabolic changes caused by loss of adhesion induce cell death. Breast Cancer Res. 2009; 11(6):307. PMID: 19930622; PMCID: PMC2815538.
    25. Limesand KH, Said S, Anderson SM. Suppression of radiation-induced salivary gland dysfunction by IGF-1. PLoS One. 2009; 4(3):e4663. PMID: 19252741; PMCID: PMC2646143.
    26. Young CD, Nolte EC, Lewis A, Serkova NJ, Anderson SM. Activated Akt1 accelerates MMTV-c-ErbB2 mammary tumourigenesis in mice without activation of ErbB3. Breast Cancer Res. 2008; 10(4):R70. PMID: 18700973; PMCID: PMC2575543.
    27. Young CD, Anderson SM. Sugar and fat - that's where it's at: metabolic changes in tumors. Breast Cancer Res. 2008; 10(1):202. PMID: 18304378; PMCID: PMC2374962.
    28. Watkin H, Richert MM, Lewis A, Terrell K, McManaman JP, Anderson SM. Lactation failure in Src knockout mice is due to impaired secretory activation. BMC Dev Biol. 2008 Jan 23; 8:6. PMID: 18215306; PMCID: PMC2266720.
    29. Rudolph MC, Neville MC, Anderson SM. Lipid synthesis in lactation: diet and the fatty acid switch. J Mammary Gland Biol Neoplasia. 2007 Dec; 12(4):269-81. PMID: 18027074.
      View in: PubMed
    30. Lyons TR, Thorburn J, Ryan PW, Thorburn A, Anderson SM, Kassenbrock CK. Regulation of the Pro-apoptotic scaffolding protein POSH by Akt. J Biol Chem. 2007 Jul 27; 282(30):21987-97. PMID: 17535800.
      View in: PubMed
    31. Anderson SM, Rudolph MC, McManaman JL, Neville MC. Key stages in mammary gland development. Secretory activation in the mammary gland: it's not just about milk protein synthesis! Breast Cancer Res. 2007; 9(1):204. PMID: 17338830; PMCID: PMC1851396.
    32. Rudolph MC, McManaman JL, Phang T, Russell T, Kominsky DJ, Serkova NJ, Stein T, Anderson SM, Neville MC. Metabolic regulation in the lactating mammary gland: a lipid synthesizing machine. Physiol Genomics. 2007 Feb 12; 28(3):323-36. PMID: 17105756.
      View in: PubMed
    33. Palmer CA, Neville MC, Anderson SM, McManaman JL. Analysis of lactation defects in transgenic mice. J Mammary Gland Biol Neoplasia. 2006 Oct; 11(3-4):269-82. PMID: 17136614.
      View in: PubMed
    34. Limesand KH, Schwertfeger KL, Anderson SM. MDM2 is required for suppression of apoptosis by activated Akt1 in salivary acinar cells. Mol Cell Biol. 2006 Dec; 26(23):8840-56. PMID: 16982679; PMCID: PMC1636839.
    35. Buser AC, Gass-Handel EK, Wyszomierski SL, Doppler W, Leonhardt SA, Schaack J, Rosen JM, Watkin H, Anderson SM, Edwards DP. Progesterone receptor repression of prolactin/signal transducer and activator of transcription 5-mediated transcription of the beta-casein gene in mammary epithelial cells. Mol Endocrinol. 2007 Jan; 21(1):106-25. PMID: 16973758.
      View in: PubMed
    36. Humphries MJ, Limesand KH, Schneider JC, Nakayama KI, Anderson SM, Reyland ME. Suppression of apoptosis in the protein kinase Cdelta null mouse in vivo. J Biol Chem. 2006 Apr 07; 281(14):9728-37. PMID: 16452485.
      View in: PubMed
    37. Kassenbrock CK, Anderson SM. Regulation of ubiquitin protein ligase activity in c-Cbl by phosphorylation-induced conformational change and constitutive activation by tyrosine to glutamate point mutations. J Biol Chem. 2004 Jul 02; 279(27):28017-27. PMID: 15117950.
      View in: PubMed
    38. Kelher MR, Ambruso DR, Elzi DJ, Anderson SM, Paterson AJ, Thurman GW, Silliman CC. Formyl-Met-Leu-Phe induces calcium-dependent tyrosine phosphorylation of Rel-1 in neutrophils. Cell Calcium. 2003 Dec; 34(6):445-55. PMID: 14572803.
      View in: PubMed
    39. Schwertfeger KL, McManaman JL, Palmer CA, Neville MC, Anderson SM. Expression of constitutively activated Akt in the mammary gland leads to excess lipid synthesis during pregnancy and lactation. J Lipid Res. 2003 Jun; 44(6):1100-12. PMID: 12700340.
      View in: PubMed
    40. Sun W, Wei X, Kesavan K, Garrington TP, Fan R, Mei J, Anderson SM, Gelfand EW, Johnson GL. MEK kinase 2 and the adaptor protein Lad regulate extracellular signal-regulated kinase 5 activation by epidermal growth factor via Src. Mol Cell Biol. 2003 Apr; 23(7):2298-308. PMID: 12640115; PMCID: PMC150715.
    41. Limesand KH, Barzen KA, Sanders LA, Sclafani RA, Raynolds MV, Reyland ME, Anderson SM, Quissell DO. Characterization of rat parotid and submandibular acinar cell apoptosis in primary culture. In Vitro Cell Dev Biol Anim. 2003 Mar-Apr; 39(3-4):170-7. PMID: 14505429; PMCID: PMC2879403.
    42. Kassenbrock CK, Hunter S, Garl P, Johnson GL, Anderson SM. Inhibition of Src family kinases blocks epidermal growth factor (EGF)-induced activation of Akt, phosphorylation of c-Cbl, and ubiquitination of the EGF receptor. J Biol Chem. 2002 Jul 12; 277(28):24967-75. PMID: 11994282.
      View in: PubMed
    Anderson's Networks
    Click the "See All" links for more information and interactive visualizations!
    Concepts Expand Description
    _
    Co-Authors Expand Description
    _
    Similar People Expand Description
    _
    Same Department Expand Description
    Physical Neighbors Expand Description
    _

    Copyright © 2017 The Regents of the University of Colorado, a body corporate. All rights reserved. (Harvard PROFILES RNS software version: 2.10.0)