Colorado PROFILES, The Colorado Clinical and Translational Sciences Institute (CCTSI)
Keywords
Last Name
Institution

Monika R Fleshner

TitleProfessor
InstitutionUniversity of Colorado Boulder
DepartmentIntegrative Physiology
Phone303/492-1483

    Collapse Research 
    Collapse research activities and funding
    R01DE021966     (WATKINS, LINDA)Sep 1, 2011 - Aug 31, 2017
    NIH
    Preventing Transition of Acute-to-Chronic Neuropathic Pain: Models, Mechanisms &
    Role: Co-Principal Investigator
    R01AI057797     (FLESHNER, MONIKA R)Jun 1, 2004 - May 31, 2010
    NIH
    Stress, Heat-Shock Proteins, and Innate Immunity
    Role: Principal Investigator
    R01MH068283     (FLESHNER, MONIKA)Jun 1, 2003 - Jan 31, 2016
    NIH
    The Neurobiology of the Stress Resistant Brain
    Role: Principal Investigator
    R01AI048555     (FLESHNER, MONIKA R)Dec 15, 2000 - Nov 30, 2004
    NIH
    EXERCISE, STRESS AND IMMUNITY--PHYSIOLOGICAL MECHANISMS
    Role: Principal Investigator
    R03AI045576     (FLESHNER, MONIKA R)Sep 30, 1999 - Sep 29, 2001
    NIH
    EXERCISE PREVENTS THE IMMUNOSUPPRESSIVE EFFECT OF STRESS
    Role: Principal Investigator
    R03MH060301     (FLESHNER, MONIKA R)Jul 1, 1999 - Jun 30, 2000
    NIH
    STRESS, EXERCISE AND INNATE IMMUNITY
    Role: Principal Investigator

    Collapse Bibliographic 
    Collapse selected publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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    1. Hopkins S, Kelley T, Roller R, Thompson RS, Colagiovanni DB, Chupka K, Fleshner M. Oral CBD-rich hemp extract modulates sterile inflammation in female and male rats. Front Physiol. 2023; 14:1112906. PMID: 37275221.
      View in: PubMed
    2. Buhr TJ, Reed CH, Wee OM, Lee JH, Yuan LL, Fleshner M, Valentine RJ, Clark PJ. The persistence of stress-induced physical inactivity in rats: an investigation of central monoamine neurotransmitters and skeletal muscle oxidative stress. Front Behav Neurosci. 2023; 17:1169151. PMID: 37273279.
      View in: PubMed
    3. Frank MG, Fleshner M, Maier SF. Exploring the immunogenic properties of SARS-CoV-2 structural proteins: PAMP:TLR signaling in the mediation of the neuroinflammatory and neurologic sequelae of COVID-19. Brain Behav Immun. 2023 07; 111:259-269. PMID: 37116592.
      View in: PubMed
    4. Bowers SJ, Summa KC, Thompson RS, Gonz?lez A, Vargas F, Olker C, Jiang P, Lowry CA, Dorrestein PC, Knight R, Wright KP, Fleshner M, Turek FW, Vitaterna MH. A Prebiotic Diet Alters the Fecal Microbiome and Improves Sleep in Response to Sleep Disruption in Rats. Front Neurosci. 2022; 16:889211. PMID: 35685770.
      View in: PubMed
    5. Frank MG, Nguyen KH, Ball JB, Hopkins S, Kelley T, Baratta MV, Fleshner M, Maier SF. SARS-CoV-2 spike S1 subunit induces neuroinflammatory, microglial and behavioral sickness responses: Evidence of PAMP-like properties. Brain Behav Immun. 2022 02; 100:267-277. PMID: 34915155.
      View in: PubMed
    6. Thompson RS, Gaffney M, Hopkins S, Kelley T, Gonzalez A, Bowers SJ, Vitaterna MH, Turek FW, Foxx CL, Lowry CA, Vargas F, Dorrestein PC, Wright KP, Knight R, Fleshner M. Ruminiclostridium 5, Parabacteroides distasonis, and bile acid profile are modulated by prebiotic diet and associate with facilitated sleep/clock realignment after chronic disruption of rhythms. Brain Behav Immun. 2021 10; 97:150-166. PMID: 34242738.
      View in: PubMed
    7. Bowers SJ, Lambert S, He S, Lowry CA, Fleshner M, Wright KP, Turek FW, Vitaterna MH. Immunization with a heat-killed bacterium, Mycobacterium vaccae NCTC 11659, prevents the development of cortical hyperarousal and a PTSD-like sleep phenotype after sleep disruption and acute stress in mice. Sleep. 2021 06 11; 44(6). PMID: 33283862.
      View in: PubMed
    8. Fleshner M. Mentorship Memoriam: Mark Laudenslager, PhD. Brain Behav Immun. 2021 05; 94:18. PMID: 33444730.
      View in: PubMed
    9. Foxx CL, Heinze JD, Gonz?lez A, Vargas F, Baratta MV, Elsayed AI, Stewart JR, Loupy KM, Arnold MR, Flux MC, Sago SA, Siebler PH, Milton LN, Lieb MW, Hassell JE, Smith DG, Lee KAK, Appiah SA, Schaefer EJ, Panitchpakdi M, Sikora NC, Weldon KC, Stamper CE, Schmidt D, Duggan DA, Mengesha YM, Ogbaselassie M, Nguyen KT, Gates CA, Schnabel K, Tran L, Jones JD, Vitaterna MH, Turek FW, Fleshner M, Dorrestein PC, Knight R, Wright KP, Lowry CA. Effects of Immunization With the Soil-Derived Bacterium Mycobacterium vaccae on Stress Coping Behaviors and Cognitive Performance in a "Two Hit" Stressor Model. Front Physiol. 2020; 11:524833. PMID: 33469429.
      View in: PubMed
    10. Fleshner M, Epperson N, Dantzer R. Those we have lost: Dr. Mark L. Laudenslager. Psychoneuroendocrinology. 2021 02; 124:105126. PMID: 34131360.
      View in: PubMed
    11. Thompson RS, Vargas F, Dorrestein PC, Chichlowski M, Berg BM, Fleshner M. Dietary prebiotics alter novel microbial dependent fecal metabolites that improve sleep. Sci Rep. 2020 03 02; 10(1):3848. PMID: 32123201.
      View in: PubMed
    12. Bowers SJ, Vargas F, Gonz?lez A, He S, Jiang P, Dorrestein PC, Knight R, Wright KP, Lowry CA, Fleshner M, Vitaterna MH, Turek FW. Repeated sleep disruption in mice leads to persistent shifts in the fecal microbiome and metabolome. PLoS One. 2020; 15(2):e0229001. PMID: 32078624.
      View in: PubMed
    13. Fleshner M. Bidirectional gut-microbial?mediated-brain signaling: A new player in stress physiology? (Commentary on O'Mahony et al., 2019). Eur J Neurosci. 2020 09; 52(5):3487-3489. PMID: 31593301.
      View in: PubMed
    14. Arnold MR, Greenwood BN, McArthur JA, Clark PJ, Fleshner M, Lowry CA. Effects of repeated voluntary or forced exercise on brainstem serotonergic systems in rats. Behav Brain Res. 2020 01 27; 378:112237. PMID: 31525404.
      View in: PubMed
    15. Sprecher KE, Ritchie HK, Burke TM, Depner CM, Smits AN, Dorrestein PC, Fleshner M, Knight R, Lowry CA, Turek FW, Vitaterna MH, Wright KP. Trait-like vulnerability of higher-order cognition and ability to maintain wakefulness during combined sleep restriction and circadian misalignment. Sleep. 2019 08 01; 42(8). PMID: 31070769.
      View in: PubMed
    16. Greenwood BN, Fleshner M. Voluntary Wheel Running: A Useful Rodent Model for Investigating the Mechanisms of Stress Robustness and Neural Circuits of Exercise Motivation. Curr Opin Behav Sci. 2019 Aug; 28:78-84. PMID: 32766411.
      View in: PubMed
    17. Mika A, Gaffney M, Roller R, Hills A, Bouchet CA, Hulen KA, Thompson RS, Chichlowski M, Berg BM, Fleshner M. Feeding the developing brain: Juvenile rats fed diet rich in prebiotics and bioactive milk fractions exhibit reduced anxiety-related behavior and modified gene expression in emotion circuits. Neurosci Lett. 2018 06 11; 677:103-109. PMID: 29409860.
      View in: PubMed
    18. Fleshner M, Crane CR. Exosomes, DAMPs and miRNA: Features of Stress Physiology and Immune Homeostasis. Trends Immunol. 2017 10; 38(10):768-776. PMID: 28838855.
      View in: PubMed
    19. Lloyd BA, Hake HS, Ishiwata T, Farmer CE, Loetz EC, Fleshner M, Bland ST, Greenwood BN. Exercise increases mTOR signaling in brain regions involved in cognition and emotional behavior. Behav Brain Res. 2017 04 14; 323:56-67. PMID: 28130174.
      View in: PubMed
    20. Thompson RS, Roller R, Mika A, Greenwood BN, Knight R, Chichlowski M, Berg BM, Fleshner M. Dietary Prebiotics and Bioactive Milk Fractions Improve NREM Sleep, Enhance REM Sleep Rebound and Attenuate the Stress-Induced Decrease in Diurnal Temperature and Gut Microbial Alpha Diversity. Front Behav Neurosci. 2016; 10:240. PMID: 28119579.
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    21. Speaker KJ, Paton MM, Cox SS, Fleshner M. A Single Bout of Fasting (24?h) Reduces Basal Cytokine Expression and Minimally Impacts the Sterile Inflammatory Response in the White Adipose Tissue of Normal Weight F344 Rats. Mediators Inflamm. 2016; 2016:1698071. PMID: 28077915.
      View in: PubMed
    22. Mika A, Day HE, Martinez A, Rumian NL, Greenwood BN, Chichlowski M, Berg BM, Fleshner M. Early life diets with prebiotics and bioactive milk fractions attenuate the impact of stress on learned helplessness behaviours and alter gene expression within neural circuits important for stress resistance. Eur J Neurosci. 2017 02; 45(3):342-357. PMID: 27763700.
      View in: PubMed
    23. Mika A, Rumian N, Loughridge AB, Fleshner M. Exercise and Prebiotics Produce Stress Resistance: Converging Impacts on Stress-Protective and Butyrate-Producing Gut Bacteria. Int Rev Neurobiol. 2016; 131:165-191. PMID: 27793217.
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    24. Grace PM, Fabisiak TJ, Green-Fulgham SM, Anderson ND, Strand KA, Kwilasz AJ, Galer EL, Walker FR, Greenwood BN, Maier SF, Fleshner M, Watkins LR. Prior voluntary wheel running attenuates neuropathic pain. Pain. 2016 09; 157(9):2012-23. PMID: 27355182.
      View in: PubMed
    25. Fleshner M, Frank M, Maier SF. Danger Signals and Inflammasomes: Stress-Evoked Sterile Inflammation in Mood Disorders. Neuropsychopharmacology. 2017 01; 42(1):36-45. PMID: 27412959.
      View in: PubMed
    26. Reber SO, Siebler PH, Donner NC, Morton JT, Smith DG, Kopelman JM, Lowe KR, Wheeler KJ, Fox JH, Hassell JE, Greenwood BN, Jansch C, Lechner A, Schmidt D, Uschold-Schmidt N, F?chsl AM, Langgartner D, Walker FR, Hale MW, Lopez Perez G, Van Treuren W, Gonz?lez A, Halweg-Edwards AL, Fleshner M, Raison CL, Rook GA, Peddada SD, Knight R, Lowry CA. Immunization with a heat-killed preparation of the environmental bacterium Mycobacterium vaccae promotes stress resilience in mice. Proc Natl Acad Sci U S A. 2016 May 31; 113(22):E3130-9. PMID: 27185913.
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    27. Fleshner M, Olivier KN, Shaw PA, Adjemian J, Strollo S, Claypool RJ, Folio L, Zelazny A, Holland SM, Prevots DR. Mortality among patients with pulmonary non-tuberculous mycobacteria disease. Int J Tuberc Lung Dis. 2016 May; 20(5):582-7. PMID: 27084809.
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    28. Thompson RS, Roller R, Greenwood BN, Fleshner M. Wheel running improves REM sleep and attenuates stress-induced flattening of diurnal rhythms in F344 rats. Stress. 2016 05; 19(3):312-24. PMID: 27124542.
      View in: PubMed
    29. Seetharaman S, Fleshner M, Park CR, Diamond DM. Influence of daily social stimulation on behavioral and physiological outcomes in an animal model of PTSD. Brain Behav. 2016 05; 6(5):e00458. PMID: 27110436.
      View in: PubMed
    30. Herrera JJ, Fedynska S, Ghasem PR, Wieman T, Clark PJ, Gray N, Loetz E, Campeau S, Fleshner M, Greenwood BN. Neurochemical and behavioural indices of exercise reward are independent of exercise controllability. Eur J Neurosci. 2016 05; 43(9):1190-202. PMID: 26833814.
      View in: PubMed
    31. Mika A, Fleshner M. Early-life exercise may promote lasting brain and metabolic health through gut bacterial metabolites. Immunol Cell Biol. 2016 Feb; 94(2):151-7. PMID: 26647967.
      View in: PubMed
    32. Clark PJ, Amat J, McConnell SO, Ghasem PR, Greenwood BN, Maier SF, Fleshner M. Running Reduces Uncontrollable Stress-Evoked Serotonin and Potentiates Stress-Evoked Dopamine Concentrations in the Rat Dorsal Striatum. PLoS One. 2015; 10(11):e0141898. PMID: 26555633.
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    33. Mika A, Bouchet CA, Bunker P, Hellwinkel JE, Spence KG, Day HE, Campeau S, Fleshner M, Greenwood BN. Voluntary exercise during extinction of auditory fear conditioning reduces the relapse of fear associated with potentiated activity of striatal direct pathway neurons. Neurobiol Learn Mem. 2015 Nov; 125:224-35. PMID: 26454156.
      View in: PubMed
    34. Mika A, Van Treuren W, Gonz?lez A, Herrera JJ, Knight R, Fleshner M. Exercise is More Effective at Altering Gut Microbial Composition and Producing Stable Changes in Lean Mass in Juvenile versus Adult Male F344 Rats. PLoS One. 2015; 10(5):e0125889. PMID: 26016739.
      View in: PubMed
    35. Zoladz PR, Park CR, Fleshner M, Diamond DM. Psychosocial predator-based animal model of PTSD produces physiological and behavioral sequelae and a traumatic memory four months following stress onset. Physiol Behav. 2015 Aug 01; 147:183-92. PMID: 25911267.
      View in: PubMed
    36. Wright KP, Drake AL, Frey DJ, Fleshner M, Desouza CA, Gronfier C, Czeisler CA. Influence of sleep deprivation and circadian misalignment on cortisol, inflammatory markers, and cytokine balance. Brain Behav Immun. 2015 Jul; 47:24-34. PMID: 25640603.
      View in: PubMed
    37. van Praag H, Fleshner M, Schwartz MW, Mattson MP. Exercise, energy intake, glucose homeostasis, and the brain. J Neurosci. 2014 Nov 12; 34(46):15139-49. PMID: 25392482.
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    38. Beninson LA, Fleshner M. Exosomes in fetal bovine serum dampen primary macrophage IL-1? response to lipopolysaccharide (LPS) challenge. Immunol Lett. 2015 Feb; 163(2):187-92. PMID: 25455591.
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    39. Greenwood BN, Thompson RS, Opp MR, Fleshner M. Repeated exposure to conditioned fear stress increases anxiety and delays sleep recovery following exposure to an acute traumatic stressor. Front Psychiatry. 2014; 5:146. PMID: 25368585.
      View in: PubMed
    40. Beninson LA, Brown PN, Loughridge AB, Saludes JP, Maslanik T, Hills AK, Woodworth T, Craig W, Yin H, Fleshner M. Acute stressor exposure modifies plasma exosome-associated heat shock protein 72 (Hsp72) and microRNA (miR-142-5p and miR-203). PLoS One. 2014; 9(9):e108748. PMID: 25259839.
      View in: PubMed
    41. Clark PJ, Ghasem PR, Mika A, Day HE, Herrera JJ, Greenwood BN, Fleshner M. Wheel running alters patterns of uncontrollable stress-induced cfos mRNA expression in rat dorsal striatum direct and indirect pathways: A possible role for plasticity in adenosine receptors. Behav Brain Res. 2014 Oct 01; 272:252-63. PMID: 25017571.
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    42. Thompson RS, Strong PV, Clark PJ, Maslanik TM, Wright KP, Greenwood BN, Fleshner M. Repeated fear-induced diurnal rhythm disruptions predict PTSD-like sensitized physiological acute stress responses in F344 rats. Acta Physiol (Oxf). 2014 Jun; 211(2):447-65. PMID: 24447583.
      View in: PubMed
    43. Beninson LA, Fleshner M. Exosomes: an emerging factor in stress-induced immunomodulation. Semin Immunol. 2014 Oct; 26(5):394-401. PMID: 24405946.
      View in: PubMed
    44. Fleshner M, Greenwood BN, Yirmiya R. Neuronal-glial mechanisms of exercise-evoked stress robustness. Curr Top Behav Neurosci. 2014; 18:1-12. PMID: 24481547.
      View in: PubMed
    45. Cox SS, Speaker KJ, Beninson LA, Craig WC, Paton MM, Fleshner M. Adrenergic and glucocorticoid modulation of the sterile inflammatory response. Brain Behav Immun. 2014 Feb; 36:183-92. PMID: 24321216.
      View in: PubMed
    46. Speaker KJ, Cox SS, Paton MM, Serebrakian A, Maslanik T, Greenwood BN, Fleshner M. Six weeks of voluntary wheel running modulates inflammatory protein (MCP-1, IL-6, and IL-10) and DAMP (Hsp72) responses to acute stress in white adipose tissue of lean rats. Brain Behav Immun. 2014 Jul; 39:87-98. PMID: 24246250.
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    47. Saludes JP, Morton LA, Coulup SK, Fiorini Z, Cook BM, Beninson L, Chapman ER, Fleshner M, Yin H. Multivalency amplifies the selection and affinity of bradykinin-derived peptides for lipid nanovesicles. Mol Biosyst. 2013 Aug; 9(8):2005-9. PMID: 23715428.
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    48. Loughridge AB, Greenwood BN, Day HE, McQueen MB, Fleshner M. Microarray analyses reveal novel targets of exercise-induced stress resistance in the dorsal raphe nucleus. Front Behav Neurosci. 2013; 7:37. PMID: 23717271.
      View in: PubMed
    49. Thompson RS, Christianson JP, Maslanik TM, Maier SF, Greenwood BN, Fleshner M. Effects of stressor controllability on diurnal physiological rhythms. Physiol Behav. 2013 Mar 15; 112-113:32-9. PMID: 23454291.
      View in: PubMed
    50. Zoladz PR, Fleshner M, Diamond DM. Differential effectiveness of tianeptine, clonidine and amitriptyline in blocking traumatic memory expression, anxiety and hypertension in an animal model of PTSD. Prog Neuropsychopharmacol Biol Psychiatry. 2013 Jul 01; 44:1-16. PMID: 23318688.
      View in: PubMed
    51. Maslanik T, Tannura K, Mahaffey L, Loughridge AB, Beninson L, Benninson L, Ursell L, Greenwood BN, Knight R, Fleshner M. Commensal bacteria and MAMPs are necessary for stress-induced increases in IL-1? and IL-18 but not IL-6, IL-10 or MCP-1. PLoS One. 2012; 7(12):e50636. PMID: 23236381.
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    52. Greenwood BN, Spence KG, Crevling DM, Clark PJ, Craig WC, Fleshner M. Exercise-induced stress resistance is independent of exercise controllability and the medial prefrontal cortex. Eur J Neurosci. 2013 Feb; 37(3):469-78. PMID: 23121339.
      View in: PubMed
    53. Morton LA, Yang H, Saludes JP, Fiorini Z, Beninson L, Chapman ER, Fleshner M, Xue D, Yin H. MARCKS-ED peptide as a curvature and lipid sensor. ACS Chem Biol. 2013 Jan 18; 8(1):218-25. PMID: 23075500.
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    54. Maslanik T, Mahaffey L, Tannura K, Beninson L, Greenwood BN, Fleshner M. The inflammasome and danger associated molecular patterns (DAMPs) are implicated in cytokine and chemokine responses following stressor exposure. Brain Behav Immun. 2013 Feb; 28:54-62. PMID: 23103443.
      View in: PubMed
    55. Greenwood BN, Strong PV, Loughridge AB, Day HE, Clark PJ, Mika A, Hellwinkel JE, Spence KG, Fleshner M. 5-HT2C receptors in the basolateral amygdala and dorsal striatum are a novel target for the anxiolytic and antidepressant effects of exercise. PLoS One. 2012; 7(9):e46118. PMID: 23049953.
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    56. Foley TE, Brooks LR, Gilligan LJ, Burghardt PR, Koch LG, Britton SL, Fleshner M. Brain activation patterns at exhaustion in rats that differ in inherent exercise capacity. PLoS One. 2012; 7(9):e45415. PMID: 23028992.
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    57. Fleshner M. Stress-evoked sterile inflammation, danger associated molecular patterns (DAMPs), microbial associated molecular patterns (MAMPs) and the inflammasome. Brain Behav Immun. 2013 Jan; 27(1):1-7. PMID: 22964544.
      View in: PubMed
    58. Hutchinson MR, Northcutt AL, Hiranita T, Wang X, Lewis SS, Thomas J, van Steeg K, Kopajtic TA, Loram LC, Sfregola C, Galer E, Miles NE, Bland ST, Amat J, Rozeske RR, Maslanik T, Chapman TR, Strand KA, Fleshner M, Bachtell RK, Somogyi AA, Yin H, Katz JL, Rice KC, Maier SF, Watkins LR. Opioid activation of toll-like receptor 4 contributes to drug reinforcement. J Neurosci. 2012 Aug 15; 32(33):11187-200. PMID: 22895704.
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    59. Saludes JP, Morton LA, Ghosh N, Beninson LA, Chapman ER, Fleshner M, Yin H. Detection of highly curved membrane surfaces using a cyclic peptide derived from synaptotagmin-I. ACS Chem Biol. 2012 Oct 19; 7(10):1629-35. PMID: 22769435.
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    60. Speaker KJ, Fleshner M. Interleukin-1 beta: a potential link between stress and the development of visceral obesity. BMC Physiol. 2012 Jun 27; 12:8. PMID: 22738239.
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    61. Thompson RS, Strong PV, Fleshner M. Physiological consequences of repeated exposures to conditioned fear. Behav Sci (Basel). 2012 Jun; 2(2):57-78. PMID: 25379216.
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    62. Greenwood BN, Loughridge AB, Sadaoui N, Christianson JP, Fleshner M. The protective effects of voluntary exercise against the behavioral consequences of uncontrollable stress persist despite an increase in anxiety following forced cessation of exercise. Behav Brain Res. 2012 Aug 01; 233(2):314-21. PMID: 22610051.
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    63. Zoladz PR, Fleshner M, Diamond DM. Psychosocial animal model of PTSD produces a long-lasting traumatic memory, an increase in general anxiety and PTSD-like glucocorticoid abnormalities. Psychoneuroendocrinology. 2012 Sep; 37(9):1531-45. PMID: 22421563.
      View in: PubMed
    64. Campisi J, Sharkey C, Johnson JD, Asea A, Maslanik T, Bernstein-Hanley I, Fleshner M. Stress-induced facilitation of host response to bacterial challenge in F344 rats is dependent on extracellular heat shock protein 72 and independent of alpha beta T cells. Stress. 2012 Nov; 15(6):637-46. PMID: 22217161.
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    65. Strong PV, Christianson JP, Loughridge AB, Amat J, Maier SF, Fleshner M, Greenwood BN. 5-hydroxytryptamine 2C receptors in the dorsal striatum mediate stress-induced interference with negatively reinforced instrumental escape behavior. Neuroscience. 2011 Dec 01; 197:132-44. PMID: 21958863.
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    66. Hains LE, Loram LC, Taylor FR, Strand KA, Wieseler JL, Barrientos RM, Young JJ, Frank MG, Sobesky J, Martin TJ, Eisenach JC, Maier SF, Johnson JD, Fleshner M, Watkins LR. Prior laparotomy or corticosterone potentiates lipopolysaccharide-induced fever and sickness behaviors. J Neuroimmunol. 2011 Oct 28; 239(1-2):53-60. PMID: 21907418.
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    67. Maslanik T, Bernstein-Hanley I, Helwig B, Fleshner M. The impact of acute-stressor exposure on splenic innate immunity: a gene expression analysis. Brain Behav Immun. 2012 Jan; 26(1):142-9. PMID: 21893187.
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    68. Fleshner M, Maier SF, Lyons DM, Raskind MA. The neurobiology of the stress-resistant brain. Stress. 2011 Sep; 14(5):498-502. PMID: 21790482.
      View in: PubMed
    69. Greenwood BN, Fleshner M. Exercise, stress resistance, and central serotonergic systems. Exerc Sport Sci Rev. 2011 Jul; 39(3):140-9. PMID: 21508844.
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    70. Zoladz PR, Park CR, Halonen JD, Salim S, Alzoubi KH, Srivareerat M, Fleshner M, Alkadhi KA, Diamond DM. Differential expression of molecular markers of synaptic plasticity in the hippocampus, prefrontal cortex, and amygdala in response to spatial learning, predator exposure, and stress-induced amnesia. Hippocampus. 2012 Mar; 22(3):577-89. PMID: 21538655.
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    71. Rozeske RR, Greenwood BN, Fleshner M, Watkins LR, Maier SF. Voluntary wheel running produces resistance to inescapable stress-induced potentiation of morphine conditioned place preference. Behav Brain Res. 2011 Jun 01; 219(2):378-81. PMID: 21262267.
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    72. Walsh NP, Gleeson M, Shephard RJ, Gleeson M, Woods JA, Bishop NC, Fleshner M, Green C, Pedersen BK, Hoffman-Goetz L, Rogers CJ, Northoff H, Abbasi A, Simon P. Position statement. Part one: Immune function and exercise. Exerc Immunol Rev. 2011; 17:6-63. PMID: 21446352.
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    73. Fleshner M. The gut microbiota: a new player in the innate immune stress response? Brain Behav Immun. 2011 Mar; 25(3):395-6. PMID: 21168480.
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    74. Greenwood BN, Foley TE, Le TV, Strong PV, Loughridge AB, Day HE, Fleshner M. Long-term voluntary wheel running is rewarding and produces plasticity in the mesolimbic reward pathway. Behav Brain Res. 2011 Mar 01; 217(2):354-62. PMID: 21070820.
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    75. Campeau S, Nyhuis TJ, Sasse SK, Kryskow EM, Herlihy L, Masini CV, Babb JA, Greenwood BN, Fleshner M, Day HE. Hypothalamic pituitary adrenal axis responses to low-intensity stressors are reduced after voluntary wheel running in rats. J Neuroendocrinol. 2010 Aug; 22(8):872-88. PMID: 20406350.
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    76. Greenwood BN, Strong PV, Fleshner M. Lesions of the basolateral amygdala reverse the long-lasting interference with shuttle box escape produced by uncontrollable stress. Behav Brain Res. 2010 Jul 29; 211(1):71-6. PMID: 20226213.
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    77. Campeau S, Nyhuis TJ, Kryskow EM, Masini CV, Babb JA, Sasse SK, Greenwood BN, Fleshner M, Day HE. Stress rapidly increases alpha 1d adrenergic receptor mRNA in the rat dentate gyrus. Brain Res. 2010 Apr 06; 1323:109-18. PMID: 20138850.
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    78. Christianson JP, Ragole T, Amat J, Greenwood BN, Strong PV, Paul ED, Fleshner M, Watkins LR, Maier SF. 5-hydroxytryptamine 2C receptors in the basolateral amygdala are involved in the expression of anxiety after uncontrollable traumatic stress. Biol Psychiatry. 2010 Feb 15; 67(4):339-45. PMID: 19914601.
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    79. Greenwood BN, Strong PV, Foley TE, Fleshner M. A behavioral analysis of the impact of voluntary physical activity on hippocampus-dependent contextual conditioning. Hippocampus. 2009 Oct; 19(10):988-1001. PMID: 19115374.
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    80. Zoladz PR, Park CR, Mu?oz C, Fleshner M, Diamond DM. Tianeptine: an antidepressant with memory-protective properties. Curr Neuropharmacol. 2008 Dec; 6(4):311-21. PMID: 19587852.
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    81. Strong PV, Greenwood BN, Fleshner M. The effects of the selective 5-HT(2C) receptor antagonist SB 242084 on learned helplessness in male Fischer 344 rats. Psychopharmacology (Berl). 2009 May; 203(4):665-75. PMID: 19037632.
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    82. Sasse SK, Greenwood BN, Masini CV, Nyhuis TJ, Fleshner M, Day HE, Campeau S. Chronic voluntary wheel running facilitates corticosterone response habituation to repeated audiogenic stress exposure in male rats. Stress. 2008 Nov; 11(6):425-37. PMID: 19065456.
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    83. Zoladz PR, Conrad CD, Fleshner M, Diamond DM. Acute episodes of predator exposure in conjunction with chronic social instability as an animal model of post-traumatic stress disorder. Stress. 2008 Jul; 11(4):259-81. PMID: 18574787.
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    84. Johnson JD, Cortez V, Kennedy SL, Foley TE, Hanson H, Fleshner M. Role of central beta-adrenergic receptors in regulating proinflammatory cytokine responses to a peripheral bacterial challenge. Brain Behav Immun. 2008 Oct; 22(7):1078-1086. PMID: 18468841.
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    85. Greenwood BN, Strong PV, Brooks L, Fleshner M. Anxiety-like behaviors produced by acute fluoxetine administration in male Fischer 344 rats are prevented by prior exercise. Psychopharmacology (Berl). 2008 Aug; 199(2):209-22. PMID: 18454279.
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    86. Park CR, Zoladz PR, Conrad CD, Fleshner M, Diamond DM. Acute predator stress impairs the consolidation and retrieval of hippocampus-dependent memory in male and female rats. Learn Mem. 2008 Apr; 15(4):271-80. PMID: 18391188.
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    156. Milligan ED, McGorry MM, Fleshner M, Gaykema RP, Goehler LE, Watkins LR, Maier SF. Subdiaphragmatic vagotomy does not prevent fever following intracerebroventricular prostaglandin E2: further evidence for the importance of vagal afferents in immune-to-brain communication. Brain Res. 1997 Aug 22; 766(1-2):240-3. PMID: 9359608.
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    174. Diamond DM, Fleshner M, Rose GM. Psychological stress repeatedly blocks hippocampal primed burst potentiation in behaving rats. Behav Brain Res. 1994 May 30; 62(1):1-9. PMID: 7917027.
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    175. Lockwood LL, Silbert LH, Fleshner M, Laudenslager ML, Watkins LR, Maier SF. Morphine-induced decreases in in vivo antibody responses. Brain Behav Immun. 1994 Mar; 8(1):24-36. PMID: 8003769.
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    177. Thomas-Dobersen DA, Butler-Simon N, Fleshner M. Evaluation of a weight management intervention program in adolescents with insulin-dependent diabetes mellitus. J Am Diet Assoc. 1993 May; 93(5):535-40. PMID: 8315162.
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    179. Fleshner M, Watkins LR, Lockwood LL, Grahn RE, Gerhardt G, Meaney MJ, Laudenslager ML, Maier SF. Blockade of the hypothalamic-pituitary-adrenal response to stress by intraventricular injection of dexamethasone: a method for studying the stress-induced peripheral effects of glucocorticoids. Psychoneuroendocrinology. 1993; 18(4):251-63. PMID: 8391148.
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    182. Fleshner M, Watkins LR, Redd JM, Kruse CA, Bellgrau D. A 9L gliosarcoma transplantation model for studying adoptive immunotherapy into the brains of conscious rats. Cell Transplant. 1992; 1(4):307-12. PMID: 1344303.
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    184. Watkins LR, Thurston CL, Fleshner M. Phenylephrine-induced antinociception: investigations of potential neural and endocrine bases. Brain Res. 1990 Oct 01; 528(2):273-84. PMID: 2271928.
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    185. Engstrom DA, Bennett MC, Stevens KE, Wilson RL, Diamond DM, Fleshner M, Rose GM. Modulation of hippocampal primed burst potentiation by anesthesia. Brain Res. 1990 Jun 25; 521(1-2):148-52. PMID: 2207654.
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    186. Diamond DM, Bennett MC, Engstrom DA, Fleshner M, Rose GM. Adrenalectomy reduces the threshold for hippocampal primed burst potentiation in the anesthetized rat. Brain Res. 1989 Jul 17; 492(1-2):356-60. PMID: 2752305.
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    187. Fleshner M, Laudenslager ML, Simons L, Maier SF. Reduced serum antibodies associated with social defeat in rats. Physiol Behav. 1989 Jun; 45(6):1183-7. PMID: 2813542.
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    188. Laudenslager ML, Fleshner M, Hofstadter P, Held PE, Simons L, Maier SF. Suppression of specific antibody production by inescapable shock: stability under varying conditions. Brain Behav Immun. 1988 Jun; 2(2):92-101. PMID: 3148338.
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