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Stephen C Dreskin

TitleProfessor
InstitutionUniversity of Colorado Denver - Anschutz Medical Campus
DepartmentSOM-MED
Phone720/848-7600

    Collapse Research 
    Collapse research activities and funding
    R01GM045578     (DRESKIN, STEPHEN C.)Jul 1, 1991 - Jun 30, 1996
    NIH/NIGMS
    SIGNAL TRANSDUCTION BY THE HIGH AFFINITY IGE RECPTOR
    Role: Principal Investigator

    R01AI052164     (DRESKIN, STEPHEN C.)Jul 1, 2002 - Jun 30, 2012
    NIH/NIAID
    Redefining the major peanut allergens
    Role: Principal Investigator

    R01AI099029     (DRESKIN, STEPHEN C.)Aug 23, 2012 - Jul 31, 2016
    NIH/NIAID
    Mapping the Critical Epitopes of Ara h 2 and Ara h 6
    Role: Principal Investigator

    Collapse Bibliographic 
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    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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    1. Chen X, Dreskin SC. Application of phage peptide display technology for the study of food allergen epitopes. Mol Nutr Food Res. 2017 Jun; 61(6). PMID: 27995755.
      View in: PubMed
    2. Moutsoglou DM, Dreskin SC. Prolonged Treatment of Peanut-Allergic Mice with Bortezomib Significantly Reduces Serum Anti-Peanut IgE but Does Not Affect Allergic Symptoms. Int Arch Allergy Immunol. 2016; 170(4):257-261. PMID: 27705966.
      View in: PubMed
    3. Dreskin SC, Halsey NA, Kelso JM, Wood RA, Hummell DS, Edwards KM, Caubet JC, Engler RJ, Gold MS, Ponvert C, Demoly P, Sanchez-Borges M, Muraro A, Li JT, Rottem M, Rosenwasser LJ. International Consensus (ICON): allergic reactions to vaccines. World Allergy Organ J. 2016; 9(1):32. PMID: 27679682.
      View in: PubMed
    4. Chen X, Negi SS, Liao S, Gao V, Braun W, Dreskin SC. Conformational IgE epitopes of peanut allergens Ara h 2 and Ara h 6. Clin Exp Allergy. 2016 Aug; 46(8):1120-1128. PMID: 27238146; PMCID: PMC4963300 [Available on 08/01/17].
    5. Moutsoglou DM, Dreskin SC. B cells establish, but do not maintain, long-lived murine anti-peanut IgE(a). Clin Exp Allergy. 2016 Apr; 46(4):640-53. PMID: 27021119; PMCID: PMC4815436 [Available on 04/01/17].
    6. Otsu K, Guo R, Dreskin SC. Epitope analysis of Ara h 2 and Ara h 6: characteristic patterns of IgE-binding fingerprints among individuals with similar clinical histories. Clin Exp Allergy. 2015 Feb; 45(2):471-84. PMID: 25213872; PMCID: PMC4470374.
    7. Patel OP, Giorno RC, Dibbern DA, Andrews KY, Durairaj S, Dreskin SC. Gene expression profiles in chronic idiopathic (spontaneous) urticaria. Allergy Rhinol (Providence). 2015 Jan; 6(2):101-10. PMID: 26302730; PMCID: PMC4541630.
    8. Bernard H, Guillon B, Drumare MF, Paty E, Dreskin SC, Wal JM, Adel-Patient K, Hazebrouck S. Allergenicity of peanut component Ara h 2: Contribution of conformational versus linear hydroxyproline-containing epitopes. J Allergy Clin Immunol. 2015 May; 135(5):1267-74.e1-8. PMID: 25483599.
      View in: PubMed
    9. Hafermann MJ, Barber GR, Dreskin SC, Lindberg GK. Fatal case of cephalexin-induced toxic epidermal necrolysis. SAGE Open Med Case Rep. 2014; 2:2050313X14532250. PMID: 27489646; PMCID: PMC4857339.
    10. Mills K, Lay J, Wu W, Robinette C, Kesic MJ, Dreskin SC, Peden DB, Hernandez M. Vitamin E, ?-tocopherol, diminishes ex vivo basophil response to dust mite allergen. Allergy. 2014 Apr; 69(4):541-4. PMID: 24697338; PMCID: PMC3989399.
    11. Leiding JW, Beakes D, Dreskin SC, Grumach A, Hide M, Reshef A, Triggiani M, Kaliner MA. Case Title: 45 year-old male with recurrent angioedema: WAO international case-based discussions. World Allergy Organ J. 2014 Jan 22; 7(1):2. PMID: 24450312; PMCID: PMC3929145.
    12. Stitt JM, Dreskin SC. The potential role of omalizumab in the treatment of chronic urticaria. Immunotherapy. 2014; 6(6):691-7. PMID: 25186602.
      View in: PubMed
    13. Koid AE, Chapman MD, Hamilton RG, van Ree R, Versteeg SA, Dreskin SC, Koppelman SJ, Wünschmann S. Ara h 6 complements Ara h 2 as an important marker for IgE reactivity to peanut. J Agric Food Chem. 2014 Jan 08; 62(1):206-13. PMID: 24328145; PMCID: PMC4055559.
    14. Halsey NA, Griffioen M, Dreskin SC, Dekker CL, Wood R, Sharma D, Jones JF, LaRussa PS, Garner J, Berger M, Proveaux T, Vellozzi C, Broder K, Setse R, Pahud B, Hrncir D, Choi H, Sparks R, Williams SE, Engler RJ, Gidudu J, Baxter R, Klein N, Edwards K, Cano M, Kelso JM. Immediate hypersensitivity reactions following monovalent 2009 pandemic influenza A (H1N1) vaccines: reports to VAERS. Vaccine. 2013 Dec 09; 31(51):6107-12. PMID: 24120547.
      View in: PubMed
    15. Stitt JM, Dreskin SC. Urticaria and autoimmunity: where are we now? Curr Allergy Asthma Rep. 2013 Oct; 13(5):555-62. PMID: 23821106.
      View in: PubMed
    16. Go AC, Barber GR, Dreskin SC. Implementing standardized intravenous antibiotic desensitizations among hospital inpatients. Am J Health Syst Pharm. 2013 Mar 15; 70(6):540-8. PMID: 23456408.
      View in: PubMed
    17. Zhuang Y, Dreskin SC. Redefining the major peanut allergens. Immunol Res. 2013 Mar; 55(1-3):125-34. PMID: 22948807; PMCID: PMC4451826.
    18. Pahud BA, Williams SE, Dekker CL, Halsey N, Larussa P, Baxter RP, Klein NP, Marchant CD, Sparks RC, Jakob K, Aukes L, Swope S, Barnett E, Lewis P, Berger M, Dreskin SC, Donofrio PD, Sejvar JJ, Slade BA, Gidudu J, Vellozzi C, Edwards KM. Clinical assessment of serious adverse events in children receiving 2009 H1N1 vaccination. Pediatr Infect Dis J. 2013 Feb; 32(2):163-8. PMID: 23334340.
      View in: PubMed
    19. Chen X, Wang Q, El-Mezayen R, Zhuang Y, Dreskin SC. Ara h 2 and Ara h 6 have similar allergenic activity and are substantially redundant. Int Arch Allergy Immunol. 2013; 160(3):251-8. PMID: 23075924; PMCID: PMC3652334.
    20. Zhuang Y, Durrani S, Hodges BD, Dreskin SC, Chen X. Expression of recombinant Ara h 6 in Pichia pastoris but not in Escherichia coli preserves allergic effector function and allows assessment of specific mutations. Mol Nutr Food Res. 2012 Jun; 56(6):986-95. PMID: 22707273.
      View in: PubMed
    21. Kulis M, Chen X, Lew J, Wang Q, Patel OP, Zhuang Y, Murray KS, Duncan MW, Porterfield HS, W Burks A, Dreskin SC. The 2S albumin allergens of Arachis hypogaea, Ara h 2 and Ara h 6, are the major elicitors of anaphylaxis and can effectively desensitize peanut-allergic mice. Clin Exp Allergy. 2012 Feb; 42(2):326-36. PMID: 22288514; PMCID: PMC3270336.
    22. Otsu K, Dreskin SC. Peanut allergy: an evolving clinical challenge. Discov Med. 2011 Oct; 12(65):319-28. PMID: 22031669.
      View in: PubMed
    23. Martucci MA, Dreskin SC. Immunologic similarities between selected autoimmune diseases and peanut allergy: possible new therapeutic approaches. Curr Allergy Asthma Rep. 2011 Aug; 11(4):334-9. PMID: 21556881.
      View in: PubMed
    24. Chen X, Zhuang Y, Wang Q, Moutsoglou D, Ruiz G, Yen SE, Dreskin SC. Analysis of the effector activity of Ara h 2 and Ara h 6 by selective depletion from a crude peanut extract. J Immunol Methods. 2011 Sep 30; 372(1-2):65-70. PMID: 21777590; PMCID: PMC3170491.
    25. Johann-Liang R, Josephs S, Dreskin SC. Analysis of anaphylaxis cases after vaccination: 10-year review from the National Vaccine Injury Compensation Program. Ann Allergy Asthma Immunol. 2011 May; 106(5):440-3. PMID: 21530879.
      View in: PubMed
    26. Dreskin SC, Ayars A, Jin Y, Atkins D, Leo HL, Song B. Association of genetic variants of CD14 with peanut allergy and elevated IgE levels in peanut allergic individuals. Ann Allergy Asthma Immunol. 2011 Feb; 106(2):170-2. PMID: 21277522.
      View in: PubMed
    27. Dreskin SC, Tripputi MT, Aubrey MT, Mustafa SS, Atkins D, Leo HL, Song B, Schlichting D, Talwar H, Wang Q, Freed BM. Peanut-allergic subjects and their peanut-tolerant siblings have large differences in peanut-specific IgG that are independent of HLA class II. Clin Immunol. 2010 Dec; 137(3):366-73. PMID: 20850383; PMCID: PMC2976616.
    28. Mathias SD, Dreskin SC, Kaplan A, Saini SS, Spector S, Rosén KE. Development of a daily diary for patients with chronic idiopathic urticaria. Ann Allergy Asthma Immunol. 2010 Aug; 105(2):142-8. PMID: 20674825.
      View in: PubMed
    29. Fonacier LS, Dreskin SC, Leung DY. Allergic skin diseases. J Allergy Clin Immunol. 2010 Feb; 125(2 Suppl 2):S138-49. PMID: 19932921.
      View in: PubMed
    30. Porterfield HS, Murray KS, Schlichting DG, Chen X, Hansen KC, Duncan MW, Dreskin SC. Effector activity of peanut allergens: a critical role for Ara h 2, Ara h 6, and their variants. Clin Exp Allergy. 2009 Jul; 39(7):1099-108. PMID: 19438581; PMCID: PMC2752635.
    31. Sheikh J, Saini SS, Kulczycki A, Dreskin SC. A survey of allergists regarding the association of thyroid autoimmunity with chronic urticaria. J Allergy Clin Immunol. 2009 May; 123(5):1173-5. PMID: 19251315.
      View in: PubMed
    32. Wood RA, Berger M, Dreskin SC, Setse R, Engler RJ, Dekker CL, Halsey NA. An algorithm for treatment of patients with hypersensitivity reactions after vaccines. Pediatrics. 2008 Sep; 122(3):e771-7. PMID: 18762513.
      View in: PubMed
    33. Amar SM, Dreskin SC. Urticaria. Prim Care. 2008 Mar; 35(1):141-57, vii-viii. PMID: 18206722.
      View in: PubMed
    34. McDermott RA, Nelson HS, Dreskin SC. Mediator measurements after daily instillation of allergen: Increased IL-5 and decreased IFN-gamma. Allergy Asthma Proc. 2008 Mar-Apr; 29(2):146-51. PMID: 18430311.
      View in: PubMed
    35. Zheng W, Dreskin SC. Thimerosal in influenza vaccine: an immediate hypersensitivity reaction. Ann Allergy Asthma Immunol. 2007 Dec; 99(6):574-5. PMID: 18219843.
      View in: PubMed
    36. El Mezayen R, El Gazzar M, Seeds MC, McCall CE, Dreskin SC, Nicolls MR. Endogenous signals released from necrotic cells augment inflammatory responses to bacterial endotoxin. Immunol Lett. 2007 Jul 31; 111(1):36-44. PMID: 17568691; PMCID: PMC3034364.
    37. McDermott RA, Porterfield HS, El Mezayen R, Burks AW, Pons L, Schlichting DG, Solomon B, Redzic JS, Harbeck RJ, Duncan MW, Hansen KC, Dreskin SC. Contribution of Ara h 2 to peanut-specific, immunoglobulin E-mediated, cell activation. Clin Exp Allergy. 2007 May; 37(5):752-63. PMID: 17456223.
      View in: PubMed
    38. El Gazzar MA, El Mezayen R, Nicolls MR, Dreskin SC. Thymoquinone attenuates proinflammatory responses in lipopolysaccharide-activated mast cells by modulating NF-kappaB nuclear transactivation. Biochim Biophys Acta. 2007 Apr; 1770(4):556-64. PMID: 17292554.
      View in: PubMed
    39. Dreskin SC. Do HLA genes play a role in the genetics of peanut allergy? Ann Allergy Asthma Immunol. 2006 Jun; 96(6):766-8. PMID: 16802762.
      View in: PubMed
    40. El Mezayen R, El Gazzar M, Nicolls MR, Marecki JC, Dreskin SC, Nomiyama H. Effect of thymoquinone on cyclooxygenase expression and prostaglandin production in a mouse model of allergic airway inflammation. Immunol Lett. 2006 Jul 15; 106(1):72-81. PMID: 16762422.
      View in: PubMed
    41. Guyer BJ, Shimamoto SR, Bradhurst AL, Grossbard EB, Dreskin SC, Nelson HS. Mast cell inhibitor R112 is well tolerated and affects prostaglandin D2 but not other mediators, symptoms, or nasal volumes in a nasal challenge model of allergic rhinitis. Allergy Asthma Proc. 2006 May-Jun; 27(3):208-13. PMID: 16913263.
      View in: PubMed
    42. Yasnowsky KM, Dreskin SC, Efaw B, Schoen D, Vedanthan PK, Alam R, Harbeck RJ. Chronic urticaria sera increase basophil CD203c expression. J Allergy Clin Immunol. 2006 Jun; 117(6):1430-4. PMID: 16751009.
      View in: PubMed
    43. El Gazzar M, El Mezayen R, Nicolls MR, Marecki JC, Dreskin SC. Downregulation of leukotriene biosynthesis by thymoquinone attenuates airway inflammation in a mouse model of allergic asthma. Biochim Biophys Acta. 2006 Jul; 1760(7):1088-95. PMID: 16624488.
      View in: PubMed
    44. El Gazzar M, El Mezayen R, Marecki JC, Nicolls MR, Canastar A, Dreskin SC. Anti-inflammatory effect of thymoquinone in a mouse model of allergic lung inflammation. Int Immunopharmacol. 2006 Jul; 6(7):1135-42. PMID: 16714217.
      View in: PubMed
    45. Dreskin SC. Genetics of food allergy. Curr Allergy Asthma Rep. 2006 Feb; 6(1):58-64. PMID: 16476197.
      View in: PubMed
    46. Dreskin SC, Andrews KY. The thyroid and urticaria. Curr Opin Allergy Clin Immunol. 2005 Oct; 5(5):408-12. PMID: 16131915.
      View in: PubMed
    47. Palmer GW, Dibbern DA, Burks AW, Bannon GA, Bock SA, Porterfield HS, McDermott RA, Dreskin SC. Comparative potency of Ara h 1 and Ara h 2 in immunochemical and functional assays of allergenicity. Clin Immunol. 2005 Jun; 115(3):302-12. PMID: 15893698.
      View in: PubMed
    48. Nanda A, O'connor M, Anand M, Dreskin SC, Zhang L, Hines B, Lane D, Wheat W, Routes JM, Sawyer R, Rosenwasser LJ, Nelson HS. Dose dependence and time course of the immunologic response to administration of standardized cat allergen extract. J Allergy Clin Immunol. 2004 Dec; 114(6):1339-44. PMID: 15577832.
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    49. Dibbern DA, Dreskin SC. Urticaria and angioedema: an overview. Immunol Allergy Clin North Am. 2004 May; 24(2):141-62, v. PMID: 15120145.
      View in: PubMed
    50. Anand MK, Nelson HS, Dreskin SC. A possible role for cyclooxygenase 2 inhibitors in the treatment of chronic urticaria. J Allergy Clin Immunol. 2003 May; 111(5):1133-6. PMID: 12743584.
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    51. Dibbern DA, Palmer GW, Williams PB, Bock SA, Dreskin SC. RBL cells expressing human Fc epsilon RI are a sensitive tool for exploring functional IgE-allergen interactions: studies with sera from peanut-sensitive patients. J Immunol Methods. 2003 Mar 01; 274(1-2):37-45. PMID: 12609531.
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    52. Ewbank PA, Murray J, Sanders K, Curran-Everett D, Dreskin S, Nelson HS. A double-blind, placebo-controlled immunotherapy dose-response study with standardized cat extract. J Allergy Clin Immunol. 2003 Jan; 111(1):155-61. PMID: 12532112.
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    53. Dreskin SC, Dale SN, Foster SM, Martin D, Buchmeier A, Nelson HS. Measurement of changes in mRNA for IL-5 in noninvasive scrapings of nasal epithelium taken from patients undergoing nasal allergen challenge. J Immunol Methods. 2002 Oct 15; 268(2):189-95. PMID: 12215387.
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    54. Dibbern DA, Claman HN, Dreskin SC. Dyspnea and pulmonary infiltrates in a 53-year-old woman with common variable immunodeficiency. Ann Allergy Asthma Immunol. 2001 Jul; 87(1):18-21. PMID: 11484734.
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    55. Widmann C, Sather S, Oyer R, Johnson GL, Dreskin SC. In vitro activity of MEKK2 and MEKK3 in detergents is a function of a valine to serine difference in the catalytic domain. Biochim Biophys Acta. 2001 May 05; 1547(1):167-73. PMID: 11343802.
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    56. Dreskin SC, Thomas GW, Dale SN, Heasley LE. Isoforms of Jun kinase are differentially expressed and activated in human monocyte/macrophage (THP-1) cells. J Immunol. 2001 May 01; 166(9):5646-53. PMID: 11313405.
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    57. Hohman RJ, Dreskin SC. Measuring degranulation of mast cells. Curr Protoc Immunol. 2001 May; Chapter 7:Unit 7.26. PMID: 18432837.
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    58. Dreskin SC. A prescription drug packaged in China and sold as an ethnic remedy. JAMA. 2000 May 10; 283(18):2393. PMID: 10815081.
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    59. Dibbern DA, Dreskin SC. Allergic fungal sinusitis. Mayo Clin Proc. 2000 Jan; 75(1):122; author reply 122-3. PMID: 10630767.
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    60. Moore JK, Gold DP, Dreskin SC, Lernmark A, Bellgrau D. A diabetogenic gene prevents T cells from receiving costimulatory signals. Cell Immunol. 1999 May 25; 194(1):90-7. PMID: 10357884.
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    61. Dreskin SC, Abraham SN. Production of TNF-alpha by murine bone marrow derived mast cells activated by the bacterial fimbrial protein, FimH. Clin Immunol. 1999 Mar; 90(3):420-4. PMID: 10075872.
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    62. Mann R, Badesch D, Zamora M, Dreskin SC. Desensitization to trimethoprim-sulfamethoxazole following lung transplantation. Chest. 1997 Apr; 111(4):1147. PMID: 9106615.
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    63. Westcott JY, Wenzel SE, Dreskin SC. Arachidonate-induced eicosanoid synthesis in RBL-2H3 cells: stimulation with antigen or A23187 induces prolonged activation of 5-lipoxygenase. Biochim Biophys Acta. 1996 Sep 06; 1303(1):74-81. PMID: 8816855.
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    64. Wiegand TW, Williams PB, Dreskin SC, Jouvin MH, Kinet JP, Tasset D. High-affinity oligonucleotide ligands to human IgE inhibit binding to Fc epsilon receptor I. J Immunol. 1996 Jul 01; 157(1):221-30. PMID: 8683119.
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    65. Williams PB, Akasawa A, Dreskin S, Selner JC. Respirable tire fragments contain specific IgE-binding and bridging latex antigens. Chest. 1996 Mar; 109(3 Suppl):13S. PMID: 8598133.
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    66. Dreskin SC. ATP-dependent activation of phospholipase C by antigen, NECA, Na3VO4, and GTP-gamma-S in permeabilized RBL cell ghosts: differential augmentation by ATP, phosphoenolpyruvate and phosphocreatine. Mol Cell Biochem. 1995 May 24; 146(2):165-70. PMID: 7565646.
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    67. Dreskin SC. A method to trap IgG antibodies within functional membrane vesicles. J Immunol Methods. 1995 Feb 13; 179(1):87-93. PMID: 7868928.
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    68. Dreskin SC, Kuhn DE, Huang Y. Phosphoenolpyruvate and creatine phosphate augment ATP and magnesium-dependent, Fc epsilon RI-mediated activation of phospholipase C in RBL cell ghosts. J Immunol. 1993 Sep 15; 151(6):3199-205. PMID: 7690796.
      View in: PubMed
    69. Dogar JH, Nemeth GG, Durdik JM, Dreskin SC. Fc epsilon RI-mediated expression of mRNA for c-fos in rat basophilic leukemia cells does not require ongoing aggregation of the receptor. Cell Signal. 1993 Sep; 5(5):605-13. PMID: 8312136.
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    70. Kuhn DE, Dreskin SC. Fc epsilon RI-mediated hydrolysis of phosphoinositides in permeable membrane vesicles. J Immunol Methods. 1993 Jan 04; 157(1-2):81-9. PMID: 8380828.
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    71. Dreskin SC, Metzger H. Fc epsilon RI-mediated hydrolysis of phosphoinositides in ghosts derived from rat basophilic leukemia cells. J Immunol. 1991 May 01; 146(9):3102-9. PMID: 1849942.
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    72. Kirshenbaum AS, Dreskin SC, Metcalfe DD. A staphylococcal protein A rosetting assay for the demonstration of high affinity IgE receptors on rIL-3-dependent human basophil-like cells grown in mixed cell cultures. J Immunol Methods. 1989 Sep 29; 123(1):55-62. PMID: 2529316.
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    73. Dreskin SC, Pribluda VS, Metzger H. IgE receptor-mediated hydrolysis of phosphoinositides by cytoplasts from rat basophilic leukemia cells. J Immunol. 1989 Jun 15; 142(12):4407-15. PMID: 2542411.
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    74. Kirshenbaum AS, Goff JP, Dreskin SC, Irani AM, Schwartz LB, Metcalfe DD. IL-3-dependent growth of basophil-like cells and mastlike cells from human bone marrow. J Immunol. 1989 Apr 01; 142(7):2424-9. PMID: 2647850.
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    75. Dreskin SC, Metzger H. The high-affinity receptor for immunoglobulin E. Prospects for the therapy of immediate hypersensitivity reactions. JAMA. 1988 Sep 02; 260(9):1265-8. PMID: 2841507.
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    76. Dreskin SC, Gallin JI. Evolution of the hyperimmunoglobulin E and recurrent infection (HIE, JOB's) syndrome in a young girl. J Allergy Clin Immunol. 1987 Nov; 80(5):746-51. PMID: 3680819.
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    77. Dreskin SC, Goldsmith PK, Strober W, Zech LA, Gallin JI. Metabolism of immunoglobulin E in patients with markedly elevated serum immunoglobulin E levels. J Clin Invest. 1987 Jun; 79(6):1764-72. PMID: 3584468; PMCID: PMC424519.
    78. Dreskin SC, Kaliner MA, Gallin JI. Elevated urinary histamine in the hyperimmunoglobulin E and recurrent infection (Job's) syndrome: association with eczematoid dermatitis and not with infection. J Allergy Clin Immunol. 1987 Mar; 79(3):515-22. PMID: 3819231.
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    79. Dreskin SC, Goldsmith PK, Gallin JI. Immunoglobulins in the hyperimmunoglobulin E and recurrent infection (Job's) syndrome. Deficiency of anti-Staphylococcus aureus immunoglobulin A. J Clin Invest. 1985 Jan; 75(1):26-34. PMID: 3871199; PMCID: PMC423391.
    80. Dreskin SC, Iberti TJ, Watson-Williams EJ. Pseudoleukemia due to infection. A case report. J Med. 1983; 14(2):147-55. PMID: 6577121.
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    81. Dreskin SC, Kostyo JL. Acute effects of growth hormone on the function of ribosomes of rat skeletal muscle. Horm Metab Res. 1980 Feb; 12(2):60-6. PMID: 7372266.
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    82. Dreskin SC, Mayall BH. Deoxyribonucleic acid cytophotometry of stained human leukocytes. 3. Thermal denaturation of chromatin. J Histochem Cytochem. 1974 Feb; 22(2):120-6. PMID: 4132621.
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