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Kristen E. Boyle

TitleAsst Professor
InstitutionUniversity of Colorado Denver - Anschutz Medical Campus
DepartmentSOM-PEDS
Phone303/724-5969

    Collapse Research 
    Collapse research activities and funding
    F32DK089743     (BOYLE, KRISTEN ELIZABETH)Jan 1, 2011 - Dec 31, 2012
    NIH/NIDDK
    Cellular Mechanisms for Insulin Resistance in Human Gestational Diabetes Mellitus
    Role: Principal Investigator

    K01DK106347     (BOYLE, KRISTEN ELIZABETH)Jul 15, 2015 - Apr 30, 2018
    NIH/NIDDK
    Human Mesenchymal Stem Cells and the Epigenetic Programming of Obesity
    Role: Principal Investigator

    Collapse Bibliographic 
    Collapse selected publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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    1. Cavalli G, Justice JN, Boyle KE, D'Alessandro A, Eisenmesser EZ, Herrera JJ, Hansen KC, Nemkov T, Stienstra R, Garlanda C, Mantovani A, Seals DR, Dagna L, Joosten LA, Ballak DB, Dinarello CA. Interleukin 37 reverses the metabolic cost of inflammation, increases oxidative respiration, and improves exercise tolerance. Proc Natl Acad Sci U S A. 2017 Feb 28; 114(9):2313-2318. PMID: 28193888.
      View in: PubMed
    2. Boyle KE, Friedman JE, Janssen RC, Underkofler C, Houmard JA, Rasouli N. Metabolic Inflexibility with Obesity and the Effects of Fenofibrate on Skeletal Muscle Fatty Acid Oxidation. Horm Metab Res. 2017 Jan; 49(1):50-57. PMID: 28103623.
      View in: PubMed
    3. Boyle KE, Friedman JE, Janssen RC, Underkofler C, Houmard JA, Rasouli N. Metabolic Inflexibility with Obesity and the Effects of Fenofibrate on Skeletal Muscle Fatty Acid Oxidation. Horm Metab Res. 2016 Aug 02. PMID: 27485593.
      View in: PubMed
    4. Shapiro AL, Boyle KE, Dabelea D, Patinkin ZW, De la Houssaye B, Ringham BM, Glueck DH, Barbour LA, Norris JM, Friedman JE. Nicotinamide Promotes Adipogenesis in Umbilical Cord-Derived Mesenchymal Stem Cells and Is Associated with Neonatal Adiposity: The Healthy Start BabyBUMP Project. PLoS One. 2016; 11(7):e0159575. PMID: 27414406; PMCID: PMC4944979.
    5. Boyle KE, Patinkin ZW, Shapiro AL, Baker PR, Dabelea D, Friedman JE. Mesenchymal Stem Cells From Infants Born to Obese Mothers Exhibit Greater Potential for Adipogenesis: The Healthy Start BabyBUMP Project. Diabetes. 2016 Mar; 65(3):647-59. PMID: 26631736; PMCID: PMC4764150 [Available on 03/01/17].
    6. Schlaepfer IR, Glodé LM, Hitz CA, Pac CT, Boyle KE, Maroni P, Deep G, Agarwal R, Lucia SM, Cramer SD, Serkova NJ, Eckel RH. Inhibition of Lipid Oxidation Increases Glucose Metabolism and Enhances 2-Deoxy-2-[(18)F]Fluoro-D-Glucose Uptake in Prostate Cancer Mouse Xenografts. Mol Imaging Biol. 2015 Aug; 17(4):529-38. PMID: 25561013; PMCID: PMC4493937.
    7. Boyle KE, Hwang H, Janssen RC, DeVente JM, Barbour LA, Hernandez TL, Mandarino LJ, Lappas M, Friedman JE. Gestational diabetes is characterized by reduced mitochondrial protein expression and altered calcium signaling proteins in skeletal muscle. PLoS One. 2014; 9(9):e106872. PMID: 25216282; PMCID: PMC4162568.
    8. Boyle KE, Newsom SA, Janssen RC, Lappas M, Friedman JE. Skeletal muscle MnSOD, mitochondrial complex II, and SIRT3 enzyme activities are decreased in maternal obesity during human pregnancy and gestational diabetes mellitus. J Clin Endocrinol Metab. 2013 Oct; 98(10):E1601-9. PMID: 23956348; PMCID: PMC3790616.
    9. Newsom SA, Boyle KE, Friedman JE. Sirtuin 3: A major control point for obesity-related metabolic diseases? Drug Discov Today Dis Mech. 2013 Jun 01; 10(1-2):e35-e40. PMID: 23997790.
      View in: PubMed
    10. Boyle KE, Zheng D, Anderson EJ, Neufer PD, Houmard JA. Mitochondrial lipid oxidation is impaired in cultured myotubes from obese humans. Int J Obes (Lond). 2012 Aug; 36(8):1025-31. PMID: 22024640; PMCID: PMC3848508.
    11. Boyle KE, Canham JP, Consitt LA, Zheng D, Koves TR, Gavin TP, Holbert D, Neufer PD, Ilkayeva O, Muoio DM, Houmard JA. A high-fat diet elicits differential responses in genes coordinating oxidative metabolism in skeletal muscle of lean and obese individuals. J Clin Endocrinol Metab. 2011 Mar; 96(3):775-81. PMID: 21190973; PMCID: PMC3047224.
    12. Howe HR, Heidal K, Choi MD, Kraus RM, Boyle K, Hickner RC. Increased adipose tissue lipolysis after a 2-week high-fat diet in sedentary overweight/obese men. Metabolism. 2011 Jul; 60(7):976-81. PMID: 21040937; PMCID: PMC3868457.
    13. Anderson EJ, Lustig ME, Boyle KE, Woodlief TL, Kane DA, Lin CT, Price JW, Kang L, Rabinovitch PS, Szeto HH, Houmard JA, Cortright RN, Wasserman DH, Neufer PD. Mitochondrial H2O2 emission and cellular redox state link excess fat intake to insulin resistance in both rodents and humans. J Clin Invest. 2009 Mar; 119(3):573-81. PMID: 19188683.
      View in: PubMed
    14. Hittel DS, Berggren JR, Shearer J, Boyle K, Houmard JA. Increased secretion and expression of myostatin in skeletal muscle from extremely obese women. Diabetes. 2009 Jan; 58(1):30-8. PMID: 18835929; PMCID: PMC2606890.
    15. Berggren JR, Boyle KE, Chapman WH, Houmard JA. Skeletal muscle lipid oxidation and obesity: influence of weight loss and exercise. Am J Physiol Endocrinol Metab. 2008 Apr; 294(4):E726-32. PMID: 18252891.
      View in: PubMed
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