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Andrew Getahun

TitleAsst Professor-Research
InstitutionUniversity of Colorado Denver - Anschutz Medical Campus
DepartmentSOM-Immunology Microbiology
Phone303/398-1228

    Collapse Bibliographic 
    Collapse selected publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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    1. Getahun A, Wemlinger SM, Rudra P, Santiago ML, van Dyk LF, Cambier JC. Impaired B cell function during viral infections due to PTEN-mediated inhibition of the PI3K pathway. J Exp Med. 2017 Apr 03; 214(4):931-941. PMID: 28341640.
      View in: PubMed
    2. Packard TA, Smith MJ, Conrad FJ, Johnson SA, Getahun A, Lindsay RS, Hinman RM, Friedman RS, Thomas JW, Cambier JC. B Cell Receptor Affinity for Insulin Dictates Autoantigen Acquisition and B Cell Functionality in Autoimmune Diabetes. J Clin Med. 2016 Nov 08; 5(11). PMID: 27834793.
      View in: PubMed
    3. Franks SE, Getahun A, Hogarth PM, Cambier JC. Targeting B cells in treatment of autoimmunity. Curr Opin Immunol. 2016 Dec; 43:39-45. PMID: 27718447.
      View in: PubMed
    4. Getahun A, Beavers NA, Larson SR, Shlomchik MJ, Cambier JC. Continuous inhibitory signaling by both SHP-1 and SHIP-1 pathways is required to maintain unresponsiveness of anergic B cells. J Exp Med. 2016 May 02; 213(5):751-69. PMID: 27114609; PMCID: PMC4854724 [Available on 11/02/16].
    5. Huang Y, Getahun A, Heiser RA, Detanico TO, Aviszus K, Kirchenbaum GA, Casper TL, Huang C, Aydintug MK, Carding SR, Ikuta K, Huang H, Wysocki LJ, Cambier JC, O'Brien RL, Born WK. ?d T Cells Shape Preimmune Peripheral B Cell Populations. J Immunol. 2016 Jan 01; 196(1):217-31. PMID: 26582947; PMCID: PMC4684964 [Available on 01/01/17].
    6. Getahun A, Cambier JC. Of ITIMs, ITAMs, and ITAMis: revisiting immunoglobulin Fc receptor signaling. Immunol Rev. 2015 Nov; 268(1):66-73. PMID: 26497513; PMCID: PMC4621791 [Available on 11/01/16].
    7. Chen Z, Getahun A, Chen X, Dollin Y, Cambier JC, Wang JH. Imbalanced PTEN and PI3K Signaling Impairs Class Switch Recombination. J Immunol. 2015 Dec 01; 195(11):5461-71. PMID: 26500350; PMCID: PMC4655169 [Available on 12/01/16].
    8. Akerlund J, Getahun A, Cambier JC. B cell expression of the SH2-containing inositol 5-phosphatase (SHIP-1) is required to establish anergy to high affinity, proteinacious autoantigens. J Autoimmun. 2015 Aug; 62:45-54. PMID: 26152931; PMCID: PMC4529775.
    9. Huang Y, Heiser RA, Detanico TO, Getahun A, Kirchenbaum GA, Casper TL, Aydintug MK, Carding SR, Ikuta K, Huang H, Cambier JC, Wysocki LJ, O'Brien RL, Born WK. ?d T cells affect IL-4 production and B-cell tolerance. Proc Natl Acad Sci U S A. 2015 Jan 06; 112(1):E39-48. PMID: 25535377; PMCID: PMC4291655.
    10. Luo W, Mayeux J, Gutierrez T, Russell L, Getahun A, Müller J, Tedder T, Parnes J, Rickert R, Nitschke L, Cambier J, Satterthwaite AB, Garrett-Sinha LA. A balance between B cell receptor and inhibitory receptor signaling controls plasma cell differentiation by maintaining optimal Ets1 levels. J Immunol. 2014 Jul 15; 193(2):909-20. PMID: 24929000; PMCID: PMC4082765.
    11. Hardy IR, Anceriz N, Rousseau F, Seefeldt MB, Hatterer E, Irla M, Buatois V, Chatel LE, Getahun A, Fletcher A, Cons L, Pontini G, Hertzberg NA, Magistrelli G, Malinge P, Smith MJ, Reith W, Kosco-Vilbois MH, Ferlin WG, Cambier JC. Anti-CD79 antibody induces B cell anergy that protects against autoimmunity. J Immunol. 2014 Feb 15; 192(4):1641-50. PMID: 24442438; PMCID: PMC3941979.
    12. Bounab Y, Getahun A, Cambier JC, Daëron M. Phosphatase regulation of immunoreceptor signaling in T cells, B cells and mast cells. Curr Opin Immunol. 2013 Jun; 25(3):313-20. PMID: 23684445; PMCID: PMC3732051.
    13. Jin L, Getahun A, Knowles HM, Mogan J, Akerlund LJ, Packard TA, Perraud AL, Cambier JC. STING/MPYS mediates host defense against Listeria monocytogenes infection by regulating Ly6C(hi) monocyte migration. J Immunol. 2013 Mar 15; 190(6):2835-43. PMID: 23378430; PMCID: PMC3593745.
    14. Getahun A, Smith MJ, Kogut I, van Dyk LF, Cambier JC. Retention of anergy and inhibition of antibody responses during acute ? herpesvirus 68 infection. J Immunol. 2012 Sep 15; 189(6):2965-74. PMID: 22904300; PMCID: PMC3436999.
    15. Rutemark C, Bergman A, Getahun A, Hallgren J, Henningsson F, Heyman B. Complement receptors 1 and 2 in murine antibody responses to IgM-complexed and uncomplexed sheep erythrocytes. PLoS One. 2012; 7(7):e41968. PMID: 22848677; PMCID: PMC3405055.
    16. O'Neill SK, Getahun A, Gauld SB, Merrell KT, Tamir I, Smith MJ, Dal Porto JM, Li QZ, Cambier JC. Monophosphorylation of CD79a and CD79b ITAM motifs initiates a SHIP-1 phosphatase-mediated inhibitory signaling cascade required for B cell anergy. Immunity. 2011 Nov 23; 35(5):746-56. PMID: 22078222; PMCID: PMC3232011.
    17. Rutemark C, Alicot E, Bergman A, Ma M, Getahun A, Ellmerich S, Carroll MC, Heyman B. Requirement for complement in antibody responses is not explained by the classic pathway activator IgM. Proc Natl Acad Sci U S A. 2011 Oct 25; 108(43):E934-42. PMID: 21987785; PMCID: PMC3203774.
    18. Yarkoni Y, Getahun A, Cambier JC. Molecular underpinning of B-cell anergy. Immunol Rev. 2010 Sep; 237(1):249-63. PMID: 20727040; PMCID: PMC2968701.
    19. Getahun A, O'Neill SK, Cambier JC. Establishing anergy as a bona fide in vivo mechanism of B cell tolerance. J Immunol. 2009 Nov 01; 183(9):5439-41. PMID: 19843930; PMCID: PMC2968702.
    20. Getahun A, Heyman B. Studies on the mechanism by which antigen-specific IgG suppresses primary antibody responses: evidence for epitope masking and decreased localization of antigen in the spleen. Scand J Immunol. 2009 Sep; 70(3):277-87. PMID: 19703017.
      View in: PubMed
    21. Carlsson F, Getahun A, Rutemark C, Heyman B. Impaired antibody responses but normal proliferation of specific CD4+ T cells in mice lacking complement receptors 1 and 2. Scand J Immunol. 2009 Aug; 70(2):77-84. PMID: 19630912.
      View in: PubMed
    22. Hjelm F, Carlsson F, Getahun A, Heyman B. Antibody-mediated regulation of the immune response. Scand J Immunol. 2006 Sep; 64(3):177-84. PMID: 16918684.
      View in: PubMed
    23. Getahun A, Heyman B. How antibodies act as natural adjuvants. Immunol Lett. 2006 Apr 15; 104(1-2):38-45. PMID: 16364455.
      View in: PubMed
    24. Getahun A, Hjelm F, Heyman B. IgE enhances antibody and T cell responses in vivo via CD23+ B cells. J Immunol. 2005 Aug 01; 175(3):1473-82. PMID: 16034084.
      View in: PubMed
    25. Getahun A, Dahlström J, Wernersson S, Heyman B. IgG2a-mediated enhancement of antibody and T cell responses and its relation to inhibitory and activating Fc gamma receptors. J Immunol. 2004 May 01; 172(9):5269-76. PMID: 15100265.
      View in: PubMed
    26. Getahun A, Heyman B. IgG- and IgE-mediated antigen presentation on MHC class II. Immunol Lett. 2004 Mar 29; 92(1-2):33-8. PMID: 15081524.
      View in: PubMed
    27. Karlsson MC, Getahun A, Heyman B. FcgammaRIIB in IgG-mediated suppression of antibody responses: different impact in vivo and in vitro. J Immunol. 2001 Nov 15; 167(10):5558-64. PMID: 11698426.
      View in: PubMed
    28. Heyman B, Dahlström J, Diaz De Ståhl T, Getahun A, Wernersson S, Karlsson MC. No evidence for a role of FcgammaRIIB in suppression of in vivo antibody responses to erythrocytes by passively administered IgG. Scand J Immunol. 2001 Apr; 53(4):331-4; discussion 339-45. PMID: 11285111.
      View in: PubMed
    29. Getahun A, Lundqvist M, Middleton D, Warr G, Pilström L. Influence of the mu-chain C-terminal sequence on polymerization of immunoglobulin M. Immunology. 1999 Jul; 97(3):408-13. PMID: 10447761; PMCID: PMC2326861.
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