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Kelly G Knupp

TitleAssociate Professor
InstitutionUniversity of Colorado Denver - Anschutz Medical Campus
DepartmentSOM-PEDS

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    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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    1. Van Nuland A, Ivanenko A, Meskis MA, Villas N, Knupp KG, Berg AT. Sleep in Dravet syndrome: A parent-driven survey. Seizure. 2021 Feb; 85:102-110. PMID: 33453590.
      View in: PubMed
    2. Berg AT, Gaebler-Spira D, Wilkening G, Zelko F, Knupp K, Dixon-Salazar T, Villas N, Meskis MA, Harwell V, Thompson T, Sims S, Nesbitt G. Nonseizure consequences of Dravet syndrome, KCNQ2-DEE, KCNB1-DEE, Lennox-Gastaut syndrome, ESES: A functional framework. Epilepsy Behav. 2020 10; 111:107287. PMID: 32759067.
      View in: PubMed
    3. Wang GS, Bourne DWA, Klawitter J, Sempio C, Chapman K, Knupp K, Wempe MF, Borgelt L, Christians U, Leonard J, Heard K, Bajaj L. Disposition of Oral Cannabidiol-Rich Cannabis Extracts in Children with Epilepsy. Clin Pharmacokinet. 2020 08; 59(8):1005-1012. PMID: 32048179.
      View in: PubMed
    4. Wirrell EC, Grinspan ZM, Knupp KG, Jiang Y, Hammeed B, Mytinger JR, Patel AD, Nabbout R, Specchio N, Cross JH, Shellhaas RA. Care Delivery for Children With Epilepsy During the COVID-19 Pandemic: An International Survey of Clinicians. J Child Neurol. 2020 11; 35(13):924-933. PMID: 32666891.
      View in: PubMed
    5. Grinspan ZM, Mytinger JR, Baumer FM, Ciliberto MA, Cohen BH, Dlugos DJ, Harini C, Hussain SA, Joshi SM, Keator CG, Knupp KG, McGoldrick PE, Nickels KC, Park JT, Pasupuleti A, Patel AD, Shahid AM, Shellhaas RA, Shrey DW, Singh RK, Wolf SM, Yozawitz EG, Yuskaitis CJ, Waugh JL, Pearl PL. Management of Infantile Spasms During the COVID-19 Pandemic. J Child Neurol. 2020 10; 35(12):828-834. PMID: 32576057.
      View in: PubMed
    6. Grinspan ZM, Mytinger JR, Baumer FM, Ciliberto MA, Cohen BH, Dlugos DJ, Harini C, Hussain SA, Joshi SM, Keator CG, Knupp KG, McGoldrick PE, Nickels KC, Park JT, Pasupuleti A, Patel AD, Pomeroy SL, Shahid AM, Shellhaas RA, Shrey DW, Singh RK, Wolf SM, Yozawitz EG, Yuskaitis CJ, Waugh JL, Pearl PL. Crisis Standard of Care: Management of Infantile Spasms during COVID-19. Ann Neurol. 2020 08; 88(2):215-217. PMID: 32445204.
      View in: PubMed
    7. Messer R, Knupp KG. Infantile Spasms: Opportunities to Improve Care. Semin Neurol. 2020 04; 40(2):236-245. PMID: 32143232.
      View in: PubMed
    8. Nabbout R, Mistry A, Zuberi S, Villeneuve N, Gil-Nagel A, Sanchez-Carpintero R, Stephani U, Laux L, Wirrell E, Knupp K, Chiron C, Farfel G, Galer BS, Morrison G, Lock M, Agarwal A, Auvin S. Fenfluramine for Treatment-Resistant Seizures in Patients With Dravet Syndrome Receiving Stiripentol-Inclusive Regimens: A Randomized Clinical Trial. JAMA Neurol. 2020 03 01; 77(3):300-308. PMID: 31790543.
      View in: PubMed
    9. Lagae L, Sullivan J, Knupp K, Laux L, Polster T, Nikanorova M, Devinsky O, Cross JH, Guerrini R, Talwar D, Miller I, Farfel G, Galer BS, Gammaitoni A, Mistry A, Morrison G, Lock M, Agarwal A, Lai WW, Ceulemans B. Fenfluramine hydrochloride for the treatment of seizures in Dravet syndrome: a randomised, double-blind, placebo-controlled trial. Lancet. 2019 12 21; 394(10216):2243-2254. PMID: 31862249.
      View in: PubMed
    10. McGarry L, Messer R, Cree-Green M, Ray K, Knupp K. Incidence of Hypertension Among Children Treated With Adrenocorticotropic Hormone (ACTH) or Prednisolone for Infantile Spasms. J Child Neurol. 2020 03; 35(3):215-220. PMID: 31769329.
      View in: PubMed
    11. Sorin LM, Knupp KG, Berg AT. New-onset seizure survey of epilepsy centers in the United States. Epilepsy Behav. 2019 12; 101(Pt A):106579. PMID: 31677582.
      View in: PubMed
    12. Knupp KG, Rice JD, Helmkamp LJ, Galinkin J, Sempio C, Jost K, Chapman KE. Prospective evaluation of oral cannabis extracts in children with epilepsy. Seizure. 2019 Nov; 72:23-27. PMID: 31550641.
      View in: PubMed
    13. Auvin S, French J, Dlugos D, Knupp KG, Perucca E, Arzimanoglou A, Whalen E, Shellhaas RA. Novel study design to assess the efficacy and tolerability of antiseizure medications for focal-onset seizures in infants and young children: A consensus document from the regulatory task force and the pediatric commission of the International League against Epilepsy (ILAE), in collaboration with the Pediatric Epilepsy Research Consortium (PERC). Epilepsia Open. 2019 Dec; 4(4):537-543. PMID: 31819909.
      View in: PubMed
    14. Berg AT, Wusthoff C, Shellhaas RA, Loddenkemper T, Grinspan ZM, Saneto RP, Knupp KG, Patel A, Sullivan JE, Kossoff EH, Chu CJ, Massey S, Valencia I, Keator C, Wirrell EC, Coryell J, Millichap JJ, Gaillard WD. Immediate outcomes in early life epilepsy: A contemporary account. Epilepsy Behav. 2019 08; 97:44-50. PMID: 31181428.
      View in: PubMed
    15. Wang GS, Bourne DWA, Klawitter J, Sempio C, Chapman K, Knupp K, Wempe MF, Borgelt L, Christians U, Heard K, Bajaj L. Disposition of oral delta-9 tetrahydrocannabinol (THC) in children receiving cannabis extracts for epilepsy. Clin Toxicol (Phila). 2020 02; 58(2):124-128. PMID: 31111749.
      View in: PubMed
    16. Eschbach K, Knupp KG. Stiripentol for the treatment of seizures in Dravet syndrome. Expert Rev Clin Pharmacol. 2019 May; 12(5):379-388. PMID: 31017478.
      View in: PubMed
    17. Daniels D, Knupp K, Benke T, Wolter-Warmerdam K, Moran M, Hickey F. Infantile Spasms in Children With Down Syndrome: Identification and Treatment Response. Glob Pediatr Health. 2019; 6:2333794X18821939. PMID: 30671494.
      View in: PubMed
    18. Ziobro J, Eschbach K, Sullivan JE, Knupp KG. Current Treatment Strategies and Future Treatment Options for Dravet Syndrome. Curr Treat Options Neurol. 2018 Oct 13; 20(12):52. PMID: 30315507.
      View in: PubMed
    19. Tolete P, Knupp K, Karlovich M, DeCarlo E, Bluvstein J, Conway E, Friedman D, Dugan P, Devinsky O. Lorcaserin therapy for severe epilepsy of childhood onset: A case series. Neurology. 2018 10 30; 91(18):837-839. PMID: 30258026.
      View in: PubMed
    20. Coryell J, Gaillard WD, Shellhaas RA, Grinspan ZM, Wirrell EC, Knupp KG, Wusthoff CJ, Keator C, Sullivan JE, Loddenkemper T, Patel A, Chu CJ, Massey S, Novotny EJ, Saneto RP, Berg AT. Neuroimaging of Early Life Epilepsy. Pediatrics. 2018 09; 142(3). PMID: 30089657.
      View in: PubMed
    21. Knupp KG, Wirrell EC. Correction to: Treatment Strategies for Dravet Syndrome. CNS Drugs. 2018 08; 32(8):783. PMID: 30027402.
      View in: PubMed
    22. Kelley SA, Knupp KG. Infantile Spasms-Have We Made Progress? Curr Neurol Neurosci Rep. 2018 04 19; 18(5):27. PMID: 29671077.
      View in: PubMed
    23. Grinspan ZM, Shellhaas RA, Coryell J, Sullivan JE, Wirrell EC, Mytinger JR, Gaillard WD, Kossoff EH, Valencia I, Knupp KG, Wusthoff C, Keator C, Ryan N, Loddenkemper T, Chu CJ, Novotny EJ, Millichap J, Berg AT. Comparative Effectiveness of Levetiracetam vs Phenobarbital for Infantile Epilepsy. JAMA Pediatr. 2018 04 01; 172(4):352-360. PMID: 29435578.
      View in: PubMed
    24. Knupp KG, Wirrell EC. Treatment Strategies for Dravet Syndrome. CNS Drugs. 2018 04; 32(4):335-350. PMID: 29594870.
      View in: PubMed
    25. Berg AT, Chakravorty S, Koh S, Grinspan ZM, Shellhaas RA, Saneto RP, Wirrell EC, Coryell J, Chu CJ, Mytinger JR, Gaillard WD, Valencia I, Knupp KG, Loddenkemper T, Sullivan JE, Poduri A, Millichap JJ, Keator C, Wusthoff C, Ryan N, Dobyns WB, Hegde M. Why West? Comparisons of clinical, genetic and molecular features of infants with and without spasms. PLoS One. 2018; 13(3):e0193599. PMID: 29518120.
      View in: PubMed
    26. Whittington MD, Knupp KG, Vanderveen G, Kim C, Gammaitoni A, Campbell JD. The direct and indirect costs of Dravet Syndrome. Epilepsy Behav. 2018 03; 80:109-113. PMID: 29414539.
      View in: PubMed
    27. Campbell JD, Whittington MD, Kim CH, VanderVeen GR, Knupp KG, Gammaitoni A. Assessing the impact of caring for a child with Dravet syndrome: Results of a caregiver survey. Epilepsy Behav. 2018 03; 80:152-156. PMID: 29414545.
      View in: PubMed
    28. Demarest ST, Shellhaas RA, Gaillard WD, Keator C, Nickels KC, Hussain SA, Loddenkemper T, Patel AD, Saneto RP, Wirrell E, Sánchez Fernández I, Chu CJ, Grinspan Z, Wusthoff CJ, Joshi S, Mohamed IS, Stafstrom CE, Stack CV, Yozawitz E, Bluvstein JS, Singh RK, Knupp KG. The impact of hypsarrhythmia on infantile spasms treatment response: Observational cohort study from the National Infantile Spasms Consortium. Epilepsia. 2017 12; 58(12):2098-2103. PMID: 29105055.
      View in: PubMed
    29. Klawitter J, Sempio C, Mörlein S, De Bloois E, Klepacki J, Henthorn T, Leehey MA, Hoffenberg EJ, Knupp K, Wang GS, Hopfer C, Kinney G, Bowler R, Foreman N, Galinkin J, Christians U, Klawitter J. An Atmospheric Pressure Chemical Ionization MS/MS Assay Using Online Extraction for the Analysis of 11 Cannabinoids and Metabolites in Human Plasma and Urine. Ther Drug Monit. 2017 10; 39(5):556-564. PMID: 28640062.
      View in: PubMed
    30. Eschbach K, Scarbro S, Juarez-Colunga E, Allen V, Hsu S, Knupp K. Growth and endocrine function in children with Dravet syndrome. Seizure. 2017 Nov; 52:117-122. PMID: 29031192.
      View in: PubMed
    31. Berg AT, Coryell J, Saneto RP, Grinspan ZM, Alexander JJ, Kekis M, Sullivan JE, Wirrell EC, Shellhaas RA, Mytinger JR, Gaillard WD, Kossoff EH, Valencia I, Knupp KG, Wusthoff C, Keator C, Dobyns WB, Ryan N, Loddenkemper T, Chu CJ, Novotny EJ, Koh S. Early-Life Epilepsies and the Emerging Role of Genetic Testing. JAMA Pediatr. 2017 09 01; 171(9):863-871. PMID: 28759667.
      View in: PubMed
    32. Shellhaas RA, Berg AT, Grinspan ZM, Wusthoff CJ, Millichap JJ, Loddenkemper T, Coryell J, Saneto RP, Chu CJ, Joshi SM, Sullivan JE, Knupp KG, Kossoff EH, Keator C, Wirrell EC, Mytinger JR, Valencia I, Massey S, Gaillard WD. Initial Treatment for Nonsyndromic Early-Life Epilepsy: An Unexpected Consensus. Pediatr Neurol. 2017 Oct; 75:73-79. PMID: 28807611.
      View in: PubMed
    33. Wallace A, Allen V, Park K, Knupp K. Infantile Spasms and Injuries of Prematurity: Short-Term Treatment-Based Response and Long-Term Outcomes. J Child Neurol. 2017 Sep; 32(10):861-866. PMID: 28635418.
      View in: PubMed
    34. Knupp KG, Scarbro S, Wilkening G, Juarez-Colunga E, Kempe A, Dempsey A. Parental Perception of Comorbidities in Children With Dravet Syndrome. Pediatr Neurol. 2017 Nov; 76:60-65. PMID: 28982531.
      View in: PubMed
    35. Knupp KG. Hormonal therapy with vigabatrin is superior to hormonal therapy alone in infantile spasms. J Pediatr. 2017 05; 184:235-238. PMID: 28434569.
      View in: PubMed
    36. Jensen MP, Brunklaus A, Dorris L, Zuberi SM, Knupp KG, Galer BS, Gammaitoni AR. The humanistic and economic burden of Dravet syndrome on caregivers and families: Implications for future research. Epilepsy Behav. 2017 05; 70(Pt A):104-109. PMID: 28431364.
      View in: PubMed
    37. Bramswig NC, Lüdecke HJ, Hamdan FF, Altmüller J, Beleggia F, Elcioglu NH, Freyer C, Gerkes EH, Demirkol YK, Knupp KG, Kuechler A, Li Y, Lowenstein DH, Michaud JL, Park K, Stegmann APA, Veenstra-Knol HE, Wieland T, Wollnik B, Engels H, Strom TM, Kleefstra T, Wieczorek D. Heterozygous HNRNPU variants cause early onset epilepsy and severe intellectual disability. Hum Genet. 2017 07; 136(7):821-834. PMID: 28393272.
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    38. Griffin A, Hamling KR, Knupp K, Hong S, Lee LP, Baraban SC. Clemizole and modulators of serotonin signalling suppress seizures in Dravet syndrome. Brain. 2017 03 01; 140(3):669-683. PMID: 28073790.
      View in: PubMed
    39. Wirrell EC, Laux L, Donner E, Jette N, Knupp K, Meskis MA, Miller I, Sullivan J, Welborn M, Berg AT. Optimizing the Diagnosis and Management of Dravet Syndrome: Recommendations From a North American Consensus Panel. Pediatr Neurol. 2017 03; 68:18-34.e3. PMID: 28284397.
      View in: PubMed
    40. Treat L, Chapman KE, Colborn KL, Knupp KG. Duration of use of oral cannabis extract in a cohort of pediatric epilepsy patients. Epilepsia. 2017 01; 58(1):123-127. PMID: 27859038.
      View in: PubMed
    41. Knupp KG, Leister E, Coryell J, Nickels KC, Ryan N, Juarez-Colunga E, Gaillard WD, Mytinger JR, Berg AT, Millichap J, Nordli DR, Joshi S, Shellhaas RA, Loddenkemper T, Dlugos D, Wirrell E, Sullivan J, Hartman AL, Kossoff EH, Grinspan ZM, Hamikawa L. Response to second treatment after initial failed treatment in a multicenter prospective infantile spasms cohort. Epilepsia. 2016 11; 57(11):1834-1842. PMID: 27615012.
      View in: PubMed
    42. Knupp KG, Coryell J, Nickels KC, Ryan N, Leister E, Loddenkemper T, Grinspan Z, Hartman AL, Kossoff EH, Gaillard WD, Mytinger JR, Joshi S, Shellhaas RA, Sullivan J, Dlugos D, Hamikawa L, Berg AT, Millichap J, Nordli DR, Wirrell E. Response to treatment in a prospective national infantile spasms cohort. Ann Neurol. 2016 Mar; 79(3):475-84. PMID: 26704170.
      View in: PubMed
    43. Kumar RM, Koh S, Knupp K, Handler MH, O'Neill BR. Surgery for infants with catastrophic epilepsy: an analysis of complications and efficacy. Childs Nerv Syst. 2015 Sep; 31(9):1479-91. PMID: 26022500.
      View in: PubMed
    44. Press CA, Knupp KG, Chapman KE. Parental reporting of response to oral cannabis extracts for treatment of refractory epilepsy. Epilepsy Behav. 2015 Apr; 45:49-52. PMID: 25845492.
      View in: PubMed
    45. Knupp K, Wirrell E. Progressive myoclonic epilepsies: it takes a village to make a diagnosis. Neurology. 2014 Feb 04; 82(5):378-9. PMID: 24384640.
      View in: PubMed
    46. Knupp K, Koh S, Park K. Pediatric epilepsy: Five new things. Neurol Clin Pract. 2012 Mar; 2(1):40-47. PMID: 29443293.
      View in: PubMed
    47. Barberio M, Reiter PD, Kaufman J, Knupp K, Dobyns EL. Continuous infusion pentobarbital for refractory status epilepticus in children. J Child Neurol. 2012 Jun; 27(6):721-6. PMID: 22156786.
      View in: PubMed
    48. Reiter PD, Huff AD, Knupp KG, Valuck RJ. Intravenous levetiracetam in the management of acute seizures in children. Pediatr Neurol. 2010 Aug; 43(2):117-21. PMID: 20610122.
      View in: PubMed
    49. Rubin DH, Suecoff SA, Knupp KG. Headaches in children. Pediatr Ann. 2006 May; 35(5):345-53. PMID: 16722293.
      View in: PubMed
    50. Johns JM, Joyner PW, McMurray MS, Elliott DL, Hofler VE, Middleton CL, Knupp K, Greenhill KW, Lomas LM, Walker CH. The effects of dopaminergic/serotonergic reuptake inhibition on maternal behavior, maternal aggression, and oxytocin in the rat. Pharmacol Biochem Behav. 2005 Aug; 81(4):769-85. PMID: 15996723.
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    51. Kulikova-Schupak R, Knupp KG, Pascual JM, Chin SS, Kairam R, Patterson MC. Rectal biopsy in the diagnosis of neuronal intranuclear hyaline inclusion disease. J Child Neurol. 2004 Jan; 19(1):59-62. PMID: 15032387.
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