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Katerina Kechris

TitleAssociate Professor
InstitutionUniversity of Colorado Denver - Anschutz Medical Campus
DepartmentCSPH-Bio Info General Ops
Phone303/724-4363

    Collapse Bibliographic 
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    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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    1. Bradford E, Jacobson S, Varasteh J, Comellas AP, Woodruff P, O'Neal W, DeMeo DL, Li X, Kim V, Cho M, Castaldi PJ, Hersh C, Silverman EK, Crapo JD, Kechris K, Bowler RP. The value of blood cytokines and chemokines in assessing COPD. Respir Res. 2017 Oct 24; 18(1):180. PMID: 29065892.
      View in: PubMed
    2. Reinhold D, Morrow JD, Jacobson S, Hu J, Ringel B, Seibold MA, Hersh CP, Kechris KJ, Bowler RP. Meta-analysis of peripheral blood gene expression modules for COPD phenotypes. PLoS One. 2017; 12(10):e0185682. PMID: 29016655.
      View in: PubMed
    3. Felix JF, Joubert BR, Baccarelli AA, Sharp GC, Almqvist C, Annesi-Maesano I, Arshad H, Baïz N, Bakermans-Kranenburg MJ, Bakulski KM, Binder EB, Bouchard L, Breton CV, Brunekreef B, Brunst KJ, Burchard EG, Bustamante M, Chatzi L, Cheng Munthe-Kaas M, Corpeleijn E, Czamara D, Dabelea D, Davey Smith G, De Boever P, Duijts L, Dwyer T, Eng C, Eskenazi B, Everson TM, Falahi F, Fallin MD, Farchi S, Fernandez MF, Gao L, Gaunt TR, Ghantous A, Gillman MW, Gonseth S, Grote V, Gruzieva O, Håberg SE, Herceg Z, Hivert MF, Holland N, Holloway JW, Hoyo C, Hu D, Huang RC, Huen K, Järvelin MR, Jima DD, Just AC, Karagas MR, Karlsson R, Karmaus W, Kechris KJ, Kere J, Kogevinas M, Koletzko B, Koppelman GH, Küpers LK, Ladd-Acosta C, Lahti J, Lambrechts N, Langie SAS, Lie RT, Liu AH, Magnus MC, Magnus P, Maguire RL, Marsit CJ, McArdle W, Melén E, Melton P, Murphy SK, Nawrot TS, Nisticò L, Nohr EA, Nordlund B, Nystad W, Oh SS, Oken E, Page CM, Perron P, Pershagen G, Pizzi C, Plusquin M, Raikkonen K, Reese SE, Reischl E, Richiardi L, Ring S, Roy RP, Rzehak P, Schoeters G, Schwartz DA, Sebert S, Snieder H, Sørensen TIA, Starling AP, Sunyer J, Taylor JA, Tiemeier H, Ullemar V, Vafeiadi M, Van Ijzendoorn MH, Vonk JM, Vriens A, Vrijheid M, Wang P, Wiemels JL, Wilcox AJ, Wright RJ, Xu CJ, Xu Z, Yang IV, Yousefi P, Zhang H, Zhang W, Zhao S, Agha G, Relton CL, Jaddoe VWV, London SJ. Cohort Profile: Pregnancy And Childhood Epigenetics (PACE) Consortium. Int J Epidemiol. 2017 Sep 13. PMID: 29025028.
      View in: PubMed
    4. Boyle KE, Patinkin ZW, Shapiro ALB, Bader C, Vanderlinden L, Kechris K, Janssen RC, Ford RJ, Smith BK, Steinberg GR, Davidson EJ, Yang IV, Dabelea D, Friedman JE. Maternal obesity alters fatty acid oxidation, AMPK activity, and associated DNA methylation in mesenchymal stem cells from human infants. Mol Metab. 2017 Nov; 6(11):1503-1516. PMID: 29107296.
      View in: PubMed
    5. Cruickshank-Quinn C, Powell R, Jacobson S, Kechris K, Bowler RP, Petrache I, Reisdorph N. Metabolomic similarities between bronchoalveolar lavage fluid and plasma in humans and mice. Sci Rep. 2017 Jul 11; 7(1):5108. PMID: 28698669.
      View in: PubMed
    6. Starling AP, Adgate JL, Hamman RF, Kechris K, Calafat AM, Ye X, Dabelea D. Perfluoroalkyl Substances during Pregnancy and Offspring Weight and Adiposity at Birth: Examining Mediation by Maternal Fasting Glucose in the Healthy Start Study. Environ Health Perspect. 2017 06 26; 125(6):067016. PMID: 28669937.
      View in: PubMed
    7. Cicchini L, Blumhagen RZ, Westrich JA, Myers ME, Warren CJ, Siska C, Raben D, Kechris KJ, Pyeon D. High-Risk Human Papillomavirus E7 Alters Host DNA Methylome and Represses HLA-E Expression in Human Keratinocytes. Sci Rep. 2017 Jun 16; 7(1):3633. PMID: 28623356.
      View in: PubMed
    8. Zemans RL, Jacobson S, Keene J, Kechris K, Miller BE, Tal-Singer R, Bowler RP. Multiple biomarkers predict disease severity, progression and mortality in COPD. Respir Res. 2017 Jun 13; 18(1):117. PMID: 28610627.
      View in: PubMed
    9. Miller MA, Danhorn T, Cruickshank-Quinn CI, Leach SM, Jacobson S, Strand MJ, Reisdorph NA, Bowler RP, Petrache I, Kechris K. Gene and metabolite time-course response to cigarette smoking in mouse lung and plasma. PLoS One. 2017; 12(6):e0178281. PMID: 28575117.
      View in: PubMed
    10. Rudra P, Shi WJ, Vestal B, Russell PH, Odell A, Dowell RD, Radcliffe RA, Saba LM, Kechris K. Model based heritability scores for high-throughput sequencing data. BMC Bioinformatics. 2017 Mar 02; 18(1):143. PMID: 28253840.
      View in: PubMed
    11. Keene JD, Jacobson S, Kechris K, Kinney GL, Foreman MG, Doerschuk CM, Make BJ, Curtis JL, Rennard SI, Barr RG, Bleecker ER, Kanner RE, Kleerup EC, Hansel NN, Woodruff PG, Han MK, Paine R, Martinez FJ, Bowler RP, O'Neal WK. Biomarkers Predictive of Exacerbations in the SPIROMICS and COPDGene Cohorts. Am J Respir Crit Care Med. 2017 Feb 15; 195(4):473-481. PMID: 27579823.
      View in: PubMed
    12. Siska C, Kechris K. Differential correlation for sequencing data. BMC Res Notes. 2017 Jan 19; 10(1):54. PMID: 28103954.
      View in: PubMed
    13. Siska C, Bowler R, Kechris K. The discordant method: a novel approach for differential correlation. Bioinformatics. 2017 Jan 01; 33(1):150. PMID: 28034858.
      View in: PubMed
    14. Serban KA, Rezania S, Petrusca DN, Poirier C, Cao D, Justice MJ, Patel M, Tsvetkova I, Kamocki K, Mikosz A, Schweitzer KS, Jacobson S, Cardoso A, Carlesso N, Hubbard WC, Kechris K, Dragnea B, Berdyshev EV, McClintock J, Petrache I. Structural and functional characterization of endothelial microparticles released by cigarette smoke. Sci Rep. 2016 Aug 17; 6:31596. PMID: 27530098; PMCID: PMC4987682.
    15. Sun W, Kechris K, Jacobson S, Drummond MB, Hawkins GA, Yang J, Chen TH, Quibrera PM, Anderson W, Barr RG, Basta PV, Bleecker ER, Beaty T, Casaburi R, Castaldi P, Cho MH, Comellas A, Crapo JD, Criner G, Demeo D, Christenson SA, Couper DJ, Curtis JL, Doerschuk CM, Freeman CM, Gouskova NA, Han MK, Hanania NA, Hansel NN, Hersh CP, Hoffman EA, Kaner RJ, Kanner RE, Kleerup EC, Lutz S, Martinez FJ, Meyers DA, Peters SP, Regan EA, Rennard SI, Scholand MB, Silverman EK, Woodruff PG, O'Neal WK, Bowler RP. Common Genetic Polymorphisms Influence Blood Biomarker Measurements in COPD. PLoS Genet. 2016 Aug; 12(8):e1006011. PMID: 27532455; PMCID: PMC4988780.
    16. Walter ND, de Jong BC, Garcia BJ, Dolganov GM, Worodria W, Byanyima P, Musisi E, Huang L, Chan ED, Van TT, Antonio M, Ayorinde A, Kato-Maeda M, Nahid P, Leung AM, Yen A, Fingerlin TE, Kechris K, Strong M, Voskuil MI, Davis JL, Schoolnik GK. Adaptation of Mycobacterium tuberculosis to Impaired Host Immunity in HIV-Infected Patients. J Infect Dis. 2016 Oct 15; 214(8):1205-11. PMID: 27534685; PMCID: PMC5034964 [Available on 10/15/17].
    17. Harrall KK, Kechris KJ, Tabakoff B, Hoffman PL, Hines LM, Tsukamoto H, Pravenec M, Printz M, Saba LM. Uncovering the liver's role in immunity through RNA co-expression networks. Mamm Genome. 2016 Oct; 27(9-10):469-84. PMID: 27401171; PMCID: PMC5002042.
    18. Lu Q, Jin C, Sun J, Bowler R, Kechris K, Kaminski N, Zhao H. Post-GWAS Prioritization Through Data Integration Provides Novel Insights on Chronic Obstructive Pulmonary Disease. Stat Biosci. 2016; 2016:1-17. PMID: 27812370.
      View in: PubMed
    19. Walter ND, Miller MA, Vasquez J, Weiner M, Chapman A, Engle M, Higgins M, Quinones AM, Rosselli V, Canono E, Yoon C, Cattamanchi A, Davis JL, Phang T, Stearman RS, Datta G, Garcia BJ, Daley CL, Strong M, Kechris K, Fingerlin TE, Reves R, Geraci MW. Blood Transcriptional Biomarkers for Active Tuberculosis among Patients in the United States: a Case-Control Study with Systematic Cross-Classifier Evaluation. J Clin Microbiol. 2016 Feb; 54(2):274-82. PMID: 26582831; PMCID: PMC4733166.
    20. Siska C, Bowler R, Kechris K. The discordant method: a novel approach for differential correlation. Bioinformatics. 2016 Mar 01; 32(5):690-6. PMID: 26520855; PMCID: PMC5006287 [Available on 03/01/17].
    21. Bradford AP, Jones K, Kechris K, Chosich J, Montague M, Warren WC, May MC, Al-Safi Z, Kuokkanen S, Appt SE, Polotsky AJ. Joint MiRNA/mRNA expression profiling reveals changes consistent with development of dysfunctional corpus luteum after weight gain. PLoS One. 2015; 10(8):e0135163. PMID: 26258540; PMCID: PMC4530955.
    22. Goldstein NB, Koster MI, Hoaglin LG, Spoelstra NS, Kechris KJ, Robinson SE, Robinson WA, Roop DR, Norris DA, Birlea SA. Narrow Band Ultraviolet B Treatment for Human Vitiligo Is Associated with Proliferation, Migration, and Differentiation of Melanocyte Precursors. J Invest Dermatol. 2015 Aug; 135(8):2068-2076. PMID: 25822579.
      View in: PubMed
    23. Walter ND, Dolganov GM, Garcia BJ, Worodria W, Andama A, Musisi E, Ayakaka I, Van TT, Voskuil MI, de Jong BC, Davidson RM, Fingerlin TE, Kechris K, Palmer C, Nahid P, Daley CL, Geraci M, Huang L, Cattamanchi A, Strong M, Schoolnik GK, Davis JL. Transcriptional Adaptation of Drug-tolerant Mycobacterium tuberculosis During Treatment of Human Tuberculosis. J Infect Dis. 2015 Sep 15; 212(6):990-8. PMID: 25762787; PMCID: PMC4548467.
    24. Newell BL, Kechris K, McQueen MB, Johnson TE. Genetic analysis of a murine QTL for diet restriction on chromosome 15. Age (Dordr). 2015 Feb; 37(1):9740. PMID: 25651884; PMCID: PMC4317404.
    25. Bowler RP, Jacobson S, Cruickshank C, Hughes GJ, Siska C, Ory DS, Petrache I, Schaffer JE, Reisdorph N, Kechris K. Plasma sphingolipids associated with chronic obstructive pulmonary disease phenotypes. Am J Respir Crit Care Med. 2015 Feb 01; 191(3):275-84. PMID: 25494452; PMCID: PMC4351578.
    26. Carolan BJ, Hughes G, Morrow J, Hersh CP, O'Neal WK, Rennard S, Pillai SG, Belloni P, Cockayne DA, Comellas AP, Han M, Zemans RL, Kechris K, Bowler RP. The association of plasma biomarkers with computed tomography-assessed emphysema phenotypes. Respir Res. 2014 Oct 12; 15:127. PMID: 25306249; PMCID: PMC4198701.
    27. Hoffman PL, Saba LM, Flink S, Grahame NJ, Kechris K, Tabakoff B. Genetics of gene expression characterizes response to selective breeding for alcohol preference. Genes Brain Behav. 2014 Nov; 13(8):743-57. PMID: 25160899; PMCID: PMC4241152.
    28. Ru Y, Kechris KJ, Tabakoff B, Hoffman P, Radcliffe RA, Bowler R, Mahaffey S, Rossi S, Calin GA, Bemis L, Theodorescu D. The multiMiR R package and database: integration of microRNA-target interactions along with their disease and drug associations. Nucleic Acids Res. 2014; 42(17):e133. PMID: 25063298; PMCID: PMC4176155.
    29. Reisdorph N, Stearman R, Kechris K, Phang TL, Reisdorph R, Prenni J, Erle DJ, Coldren C, Schey K, Nesvizhskii A, Geraci M. Hands-on workshops as an effective means of learning advanced technologies including genomics, proteomics and bioinformatics. Genomics Proteomics Bioinformatics. 2013 Dec; 11(6):368-77. PMID: 24316330; PMCID: PMC4049090.
    30. Hughes G, Cruickshank-Quinn C, Reisdorph R, Lutz S, Petrache I, Reisdorph N, Bowler R, Kechris K. MSPrep--summarization, normalization and diagnostics for processing of mass spectrometry-based metabolomic data. Bioinformatics. 2014 Jan 01; 30(1):133-4. PMID: 24174567; PMCID: PMC3866554.
    31. Bowler RP, Bahr TM, Hughes G, Lutz S, Kim YI, Coldren CD, Reisdorph N, Kechris KJ. Integrative omics approach identifies interleukin-16 as a biomarker of emphysema. OMICS. 2013 Dec; 17(12):619-26. PMID: 24138069; PMCID: PMC3837437.
    32. Howard JB, Kechris KJ, Rees DC, Glazer AN. Multiple amino acid sequence alignment nitrogenase component 1: insights into phylogenetics and structure-function relationships. PLoS One. 2013; 8(9):e72751. PMID: 24019874; PMCID: PMC3760896.
    33. Carolan BJ, Kim YI, Williams AA, Kechris K, Lutz S, Reisdorph N, Bowler RP. The association of adiponectin with computed tomography phenotypes in chronic obstructive pulmonary disease. Am J Respir Crit Care Med. 2013 Sep 01; 188(5):561-6. PMID: 23777323; PMCID: PMC3827701.
    34. De S, Pedersen BS, Kechris K. The dilemma of choosing the ideal permutation strategy while estimating statistical significance of genome-wide enrichment. Brief Bioinform. 2014 Nov; 15(6):919-28. PMID: 23956260; PMCID: PMC4271068.
    35. Bahr TM, Hughes GJ, Armstrong M, Reisdorph R, Coldren CD, Edwards MG, Schnell C, Kedl R, LaFlamme DJ, Reisdorph N, Kechris KJ, Bowler RP. Peripheral blood mononuclear cell gene expression in chronic obstructive pulmonary disease. Am J Respir Cell Mol Biol. 2013 Aug; 49(2):316-23. PMID: 23590301; PMCID: PMC3824029.
    36. Dvorkin D, Biehs B, Kechris K. A graphical model method for integrating multiple sources of genome-scale data. Stat Appl Genet Mol Biol. 2013 Aug; 12(4):469-87. PMID: 23934610; PMCID: PMC4867227.
    37. Vanderlinden LA, Saba LM, Kechris K, Miles MF, Hoffman PL, Tabakoff B. Whole brain and brain regional coexpression network interactions associated with predisposition to alcohol consumption. PLoS One. 2013; 8(7):e68878. PMID: 23894363; PMCID: PMC3720886.
    38. Baldea I, Costin GE, Shellman Y, Kechris K, Olteanu ED, Filip A, Cosgarea MR, Norris DA, Birlea SA. Biphasic pro-melanogenic and pro-apoptotic effects of all-trans-retinoic acid (ATRA) on human melanocytes: time-course study. J Dermatol Sci. 2013 Nov; 72(2):168-76. PMID: 23867358.
      View in: PubMed
    39. Siewert E, Kechris KJ. Modeling considerations for using expression data from multiple species. Stat Med. 2013 Oct 15; 32(23):4057-70. PMID: 23703923; PMCID: PMC4964853.
    40. West NA, Kechris K, Dabelea D. Exposure to Maternal Diabetes in Utero and DNA Methylation Patterns in the Offspring. Immunometabolism. 2013 Mar; 1:1-9. PMID: 23741625.
      View in: PubMed
    41. Pedersen BS, Schwartz DA, Yang IV, Kechris KJ. Comb-p: software for combining, analyzing, grouping and correcting spatially correlated P-values. Bioinformatics. 2012 Nov 15; 28(22):2986-8. PMID: 22954632; PMCID: PMC3496335.
    42. Downing C, Flink S, Florez-McClure ML, Johnson TE, Tabakoff B, Kechris KJ. Gene expression changes in C57BL/6J and DBA/2J mice following prenatal alcohol exposure. Alcohol Clin Exp Res. 2012 Sep; 36(9):1519-29. PMID: 22530671; PMCID: PMC3407322.
    43. Pollock DD, de Koning AP, Kim H, Castoe TA, Churchill ME, Kechris KJ. Bayesian analysis of high-throughput quantitative measurement of protein-DNA interactions. PLoS One. 2011; 6(11):e26105. PMID: 22069446; PMCID: PMC3206046.
    44. Bennett B, Saba LM, Hornbaker CK, Kechris KJ, Hoffman P, Tabakoff B. Genetical genomic analysis of complex phenotypes using the PhenoGen website. Behav Genet. 2011 Jul; 41(4):625-8. PMID: 21184165; PMCID: PMC3121939.
    45. Saba LM, Bennett B, Hoffman PL, Barcomb K, Ishii T, Kechris K, Tabakoff B. A systems genetic analysis of alcohol drinking by mice, rats and men: influence of brain GABAergic transmission. Neuropharmacology. 2011 Jun; 60(7-8):1269-80. PMID: 21185315; PMCID: PMC3079014.
    46. Hoffman PL, Bennett B, Saba LM, Bhave SV, Carosone-Link PJ, Hornbaker CK, Kechris KJ, Williams RW, Tabakoff B. Using the Phenogen website for 'in silico' analysis of morphine-induced analgesia: identifying candidate genes. Addict Biol. 2011 Jul; 16(3):393-404. PMID: 21054686; PMCID: PMC3115429.
    47. Biehs B, Kechris K, Liu S, Kornberg TB. Hedgehog targets in the Drosophila embryo and the mechanisms that generate tissue-specific outputs of Hedgehog signaling. Development. 2010 Nov; 137(22):3887-98. PMID: 20978080; PMCID: PMC3049281.
    48. Kechris KJ, Biehs B, Kornberg TB. Generalizing moving averages for tiling arrays using combined p-value statistics. Stat Appl Genet Mol Biol. 2010; 9:Article29. PMID: 20812907; PMCID: PMC2942027.
    49. Tabakoff B, Saba L, Printz M, Flodman P, Hodgkinson C, Goldman D, Koob G, Richardson HN, Kechris K, Bell RL, Hübner N, Heinig M, Pravenec M, Mangion J, Legault L, Dongier M, Conigrave KM, Whitfield JB, Saunders J, Grant B, Hoffman PL. Genetical genomic determinants of alcohol consumption in rats and humans. BMC Biol. 2009 Oct 27; 7:70. PMID: 19874574; PMCID: PMC2777866.
    50. Siewert EA, Kechris KJ. Prediction of motifs based on a repeated-measures model for integrating cross-species sequence and expression data. Stat Appl Genet Mol Biol. 2009; 8:Article 36. PMID: 19799555.
      View in: PubMed
    51. Glazer AN, Kechris KJ. Conserved amino acid sequence features in the alpha subunits of MoFe, VFe, and FeFe nitrogenases. PLoS One. 2009 Jul 03; 4(7):e6136. PMID: 19578539; PMCID: PMC2700964.
    52. Kechris K, Li H. c-REDUCE: incorporating sequence conservation to detect motifs that correlate with expression. BMC Bioinformatics. 2008 Nov 28; 9:506. PMID: 19040743; PMCID: PMC2626603.
    53. Kechris K, Yang YH, Yeh RF. Prediction of alternatively skipped exons and splicing enhancers from exon junction arrays. BMC Genomics. 2008 Nov 20; 9:551. PMID: 19021909; PMCID: PMC2631580.
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