Colorado PROFILES, The Colorado Clinical and Translational Sciences Institute (CCTSI)
Keywords
Last Name
Institution
Menu

Contact Us
If you have any questions or feedback please contact us.

Laurent Camille Gapin

TitleProfessor
InstitutionUniversity of Colorado Denver - Anschutz Medical Campus
DepartmentSOM-Immunology Microbiology
Phone303/724-8667

    Collapse Research 
    Collapse research activities and funding
    R01AI057485     (GAPIN, LAURENT)Mar 1, 2004 - Feb 28, 2010
    NIH/NIAID
    Homeostasis of Valpha14i Natural Killer T Cells
    Role: Principal Investigator
    R21AI076463     (GAPIN, LAURENT)Jul 1, 2008 - Jun 30, 2011
    NIH/NIAID
    Visualization of Va14i NKT cells in vivo
    Role: Principal Investigator
    R56AI078246     (GAPIN, LAURENT)May 22, 2009 - Apr 30, 2011
    NIH/NIAID
    Structural Requirements of glycolipid/CD1d Recognition by NKT Cells
    Role: Principal Investigator
    R21AI090450     (GAPIN, LAURENT)Jun 1, 2010 - May 31, 2013
    NIH/NIAID
    CD1d2-Selected iNKT Cells
    Role: Principal Investigator
    R01AI092108     (GAPIN, LAURENT)Aug 4, 2011 - Jul 31, 2015
    NIH/NIAID
    iNKT Cell Recognition of Endogenous Lipid Antigens
    Role: Principal Investigator
    R21AI121761     (GAPIN, LAURENT)Jan 1, 2016 - Dec 31, 2017
    NIH/NIAID
    Inherent reactivity of T cell antigen receptors for MHC molecules
    Role: Principal Investigator
    R21AI124076     (GAPIN, LAURENT)Aug 1, 2016 - Jul 31, 2018
    NIH/NIAID
    Regulation of Natural Killer T cell lineage diversification by the Src-like Adaptor protein 2
    Role: Principal Investigator

    Collapse Bibliographic 
    Collapse selected publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
    List All   |   Timeline
    1. Krovi SH, Gapin L. iNKT cells need UTX-tra demethylation. Nat Immunol. 2017 Jan 19; 18(2):148-150. PMID: 28102220.
      View in: PubMed
    2. Gras S, Van Rhijn I, Shahine A, Cheng TY, Bhati M, Tan LL, Halim H, Tuttle KD, Gapin L, Le Nours J, Moody DB, Rossjohn J. T cell receptor recognition of CD1b presenting a mycobacterial glycolipid. Nat Commun. 2016 Oct 27; 7:13257. PMID: 27807341.
      View in: PubMed
    3. Silberman D, Krovi SH, Tuttle KD, Crooks J, Reisdorph R, White J, Gross J, Matsuda JL, Gapin L, Marrack P, Kappler JW. Class II major histocompatibility complex mutant mice to study the germ-line bias of T-cell antigen receptors. Proc Natl Acad Sci U S A. 2016 Sep 20; 113(38):E5608-17. PMID: 27588903.
      View in: PubMed
    4. Krovi SH, Gapin L. Structure and function of the non-classical major histocompatibility complex molecule MR1. Immunogenetics. 2016 Aug; 68(8):549-59. PMID: 27448212.
      View in: PubMed
    5. Zhang J, Bedel R, Krovi SH, Tuttle KD, Zhang B, Gross J, Gapin L, Matsuda JL. Mutation of the Traj18 gene segment using TALENs to generate Natural Killer T cell deficient mice. Sci Rep. 2016 Jun 03; 6:27375. PMID: 27256918; PMCID: PMC4891675.
      View in: PubMed, PubMed Central
    6. Krovi SH, Gapin L. Revealing the TCR bias for MHC molecules. Proc Natl Acad Sci U S A. 2016 Mar 15; 113(11):2809-11. PMID: 26933216; PMCID: PMC4801276.
      View in: PubMed, PubMed Central
    7. Gapin L. Development of invariant natural killer T cells. Curr Opin Immunol. 2016 Apr; 39:68-74. PMID: 26802287; PMCID: PMC4801673 [Available on 04/01/17].
      View in: PubMed, PubMed Central
    8. Krovi SH, Gapin L. It is time to beelieve the CD1a hype! Eur J Immunol. 2016 Jan; 46(1):56-9. PMID: 26617406; PMCID: PMC4758348 [Available on 01/01/17].
      View in: PubMed, PubMed Central
    9. Pennock ND, Gapin L, Kedl RM. IL-27 is required for shaping the magnitude, affinity distribution, and memory of T cells responding to subunit immunization. Proc Natl Acad Sci U S A. 2014 Nov 18; 111(46):16472-7. PMID: 25267651; PMCID: PMC4246334.
      View in: PubMed, PubMed Central
    10. Gapin L. Check MAIT. J Immunol. 2014 May 15; 192(10):4475-80. PMID: 24795465; PMCID: PMC4025967.
      View in: PubMed, PubMed Central
    11. Bedel R, Berry R, Mallevaey T, Matsuda JL, Zhang J, Godfrey DI, Rossjohn J, Kappler JW, Marrack P, Gapin L. Effective functional maturation of invariant natural killer T cells is constrained by negative selection and T-cell antigen receptor affinity. Proc Natl Acad Sci U S A. 2014 Jan 07; 111(1):E119-28. PMID: 24344267; PMCID: PMC3890789.
      View in: PubMed, PubMed Central
    12. Gapin L, Godfrey DI, Rossjohn J. Natural Killer T cell obsession with self-antigens. Curr Opin Immunol. 2013 Apr; 25(2):168-73. PMID: 23384972; PMCID: PMC3646945.
      View in: PubMed, PubMed Central
    13. Sosinowski T, White JT, Cross EW, Haluszczak C, Marrack P, Gapin L, Kedl RM. CD8a+ dendritic cell trans presentation of IL-15 to naive CD8+ T cells produces antigen-inexperienced T cells in the periphery with memory phenotype and function. J Immunol. 2013 Mar 01; 190(5):1936-47. PMID: 23355737; PMCID: PMC3578102.
      View in: PubMed, PubMed Central
    14. Young MH, U'Ren L, Huang S, Mallevaey T, Scott-Browne J, Crawford F, Lantz O, Hansen TH, Kappler J, Marrack P, Gapin L. MAIT cell recognition of MR1 on bacterially infected and uninfected cells. PLoS One. 2013; 8(1):e53789. PMID: 23342002; PMCID: PMC3544856.
      View in: PubMed, PubMed Central
    15. Young MH, Gapin L. Mucosal associated invariant T cells: don't forget your vitamins. Cell Res. 2013 Apr; 23(4):460-2. PMID: 23208418; PMCID: PMC3616427.
      View in: PubMed, PubMed Central
    16. Rossjohn J, Pellicci DG, Patel O, Gapin L, Godfrey DI. Recognition of CD1d-restricted antigens by natural killer T cells. Nat Rev Immunol. 2012 Dec; 12(12):845-57. PMID: 23154222; PMCID: PMC3740582.
      View in: PubMed, PubMed Central
    17. Yin L, Scott-Browne J, Kappler JW, Gapin L, Marrack P. T cells and their eons-old obsession with MHC. Immunol Rev. 2012 Nov; 250(1):49-60. PMID: 23046122; PMCID: PMC3963424.
      View in: PubMed, PubMed Central
    18. Bjordahl RL, Gapin L, Marrack P, Refaeli Y. iNKT cells suppress the CD8+ T cell response to a murine Burkitt's-like B cell lymphoma. PLoS One. 2012; 7(8):e42635. PMID: 22880059; PMCID: PMC3413636.
      View in: PubMed, PubMed Central
    19. Patel O, Pellicci DG, Gras S, Sandoval-Romero ML, Uldrich AP, Mallevaey T, Clarke AJ, Le Nours J, Theodossis A, Cardell SL, Gapin L, Godfrey DI, Rossjohn J. Recognition of CD1d-sulfatide mediated by a type II natural killer T cell antigen receptor. Nat Immunol. 2012 Sep; 13(9):857-63. PMID: 22820603.
      View in: PubMed
    20. Bedel R, Matsuda JL, Brigl M, White J, Kappler J, Marrack P, Gapin L. Lower TCR repertoire diversity in Traj18-deficient mice. Nat Immunol. 2012 Jul 19; 13(8):705-6. PMID: 22814339; PMCID: PMC3748587.
      View in: PubMed, PubMed Central
    21. Garcia KC, Gapin L, Adams JJ, Birnbaum ME, Scott-Browne JP, Kappler JW, Marrack P. A closer look at TCR germline recognition. Immunity. 2012 Jun 29; 36(6):887-8. PMID: 22705103; PMCID: PMC4237060.
      View in: PubMed, PubMed Central
    22. Baker RL, Mallevaey T, Gapin L, Haskins K. T cells interact with T cells via CD40-CD154 to promote autoimmunity in type 1 diabetes. Eur J Immunol. 2012 Mar; 42(3):672-80. PMID: 22488364; PMCID: PMC3697870.
      View in: PubMed, PubMed Central
    23. Nakayama M, Castoe T, Sosinowski T, He X, Johnson K, Haskins K, Vignali DA, Gapin L, Pollock D, Eisenbarth GS. Germline TRAV5D-4 T-cell receptor sequence targets a primary insulin peptide of NOD mice. Diabetes. 2012 Apr; 61(4):857-65. PMID: 22315318; PMCID: PMC3314349.
      View in: PubMed, PubMed Central
    24. Patel O, Pellicci DG, Uldrich AP, Sullivan LC, Bhati M, McKnight M, Richardson SK, Howell AR, Mallevaey T, Zhang J, Bedel R, Besra GS, Brooks AG, Kjer-Nielsen L, McCluskey J, Porcelli SA, Gapin L, Rossjohn J, Godfrey DI. Vß2 natural killer T cell antigen receptor-mediated recognition of CD1d-glycolipid antigen. Proc Natl Acad Sci U S A. 2011 Nov 22; 108(47):19007-12. PMID: 22065767; PMCID: PMC3223435.
      View in: PubMed, PubMed Central
    25. Scott-Browne JP, Crawford F, Young MH, Kappler JW, Marrack P, Gapin L. Evolutionarily conserved features contribute to aß T cell receptor specificity. Immunity. 2011 Oct 28; 35(4):526-35. PMID: 21962492; PMCID: PMC3245739.
      View in: PubMed, PubMed Central
    26. Pellicci DG, Clarke AJ, Patel O, Mallevaey T, Beddoe T, Le Nours J, Uldrich AP, McCluskey J, Besra GS, Porcelli SA, Gapin L, Godfrey DI, Rossjohn J. Recognition of ß-linked self glycolipids mediated by natural killer T cell antigen receptors. Nat Immunol. 2011 Jul 31; 12(9):827-33. PMID: 21804559.
      View in: PubMed
    27. Mallevaey T, Clarke AJ, Scott-Browne JP, Young MH, Roisman LC, Pellicci DG, Patel O, Vivian JP, Matsuda JL, McCluskey J, Godfrey DI, Marrack P, Rossjohn J, Gapin L. A molecular basis for NKT cell recognition of CD1d-self-antigen. Immunity. 2011 Mar 25; 34(3):315-26. PMID: 21376640; PMCID: PMC3070541.
      View in: PubMed, PubMed Central
    28. Wun KS, Cameron G, Patel O, Pang SS, Pellicci DG, Sullivan LC, Keshipeddy S, Young MH, Uldrich AP, Thakur MS, Richardson SK, Howell AR, Illarionov PA, Brooks AG, Besra GS, McCluskey J, Gapin L, Porcelli SA, Godfrey DI, Rossjohn J. A molecular basis for the exquisite CD1d-restricted antigen specificity and functional responses of natural killer T cells. Immunity. 2011 Mar 25; 34(3):327-39. PMID: 21376639; PMCID: PMC3064745.
      View in: PubMed, PubMed Central
    29. Young MH, Gapin L. Group 1 CD1-restricted T cells take center stage. Eur J Immunol. 2011 Mar; 41(3):592-4. PMID: 21341260.
      View in: PubMed
    30. Matsuda H, Takeda K, Koya T, Okamoto M, Shiraishi Y, Miyahara N, Dakhama A, Matsuda JL, Gapin L, Gelfand EW. Plasticity of invariant NKT cell regulation of allergic airway disease is dependent on IFN-gamma production. J Immunol. 2010 Jul 01; 185(1):253-62. PMID: 20525882.
      View in: PubMed
    31. Gapin L. iNKT cell autoreactivity: what is 'self' and how is it recognized? Nat Rev Immunol. 2010 Apr; 10(4):272-7. PMID: 20224567; PMCID: PMC3070484.
      View in: PubMed, PubMed Central
    32. McWilliams JA, Sanchez PJ, Haluszczak C, Gapin L, Kedl RM. Multiple innate signaling pathways cooperate with CD40 to induce potent, CD70-dependent cellular immunity. Vaccine. 2010 Feb 10; 28(6):1468-76. PMID: 19995538; PMCID: PMC2822033.
      View in: PubMed, PubMed Central
    33. Florence WC, Xia C, Gordy LE, Chen W, Zhang Y, Scott-Browne J, Kinjo Y, Yu KO, Keshipeddy S, Pellicci DG, Patel O, Kjer-Nielsen L, McCluskey J, Godfrey DI, Rossjohn J, Richardson SK, Porcelli SA, Howell AR, Hayakawa K, Gapin L, Zajonc DM, Wang PG, Joyce S. Adaptability of the semi-invariant natural killer T-cell receptor towards structurally diverse CD1d-restricted ligands. EMBO J. 2009 Dec 02; 28(23):3781. PMID: 19953109; PMCID: PMC2790496.
      View in: PubMed, PubMed Central
    34. Florence WC, Xia C, Gordy LE, Chen W, Zhang Y, Scott-Browne J, Kinjo Y, Yu KO, Keshipeddy S, Pellicci DG, Patel O, Kjer-Nielsen L, McCluskey J, Godfrey DI, Rossjohn J, Richardson SK, Porcelli SA, Howell AR, Hayakawa K, Gapin L, Zajonc DM, Wang PG, Joyce S. Adaptability of the semi-invariant natural killer T-cell receptor towards structurally diverse CD1d-restricted ligands. EMBO J. 2009 Nov 18; 28(22):3579-90. PMID: 19816402; PMCID: PMC2782097.
      View in: PubMed, PubMed Central
    35. Mallevaey T, Scott-Browne JP, Matsuda JL, Young MH, Pellicci DG, Patel O, Thakur M, Kjer-Nielsen L, Richardson SK, Cerundolo V, Howell AR, McCluskey J, Godfrey DI, Rossjohn J, Marrack P, Gapin L. T cell receptor CDR2 beta and CDR3 beta loops collaborate functionally to shape the iNKT cell repertoire. Immunity. 2009 Jul 17; 31(1):60-71. PMID: 19592274; PMCID: PMC2965025.
      View in: PubMed, PubMed Central
    36. Pellicci DG, Patel O, Kjer-Nielsen L, Pang SS, Sullivan LC, Kyparissoudis K, Brooks AG, Reid HH, Gras S, Lucet IS, Koh R, Smyth MJ, Mallevaey T, Matsuda JL, Gapin L, McCluskey J, Godfrey DI, Rossjohn J. Differential recognition of CD1d-alpha-galactosyl ceramide by the V beta 8.2 and V beta 7 semi-invariant NKT T cell receptors. Immunity. 2009 Jul 17; 31(1):47-59. PMID: 19592275; PMCID: PMC2765864.
      View in: PubMed, PubMed Central
    37. Gapin L. Where do MAIT cells fit in the family of unconventional T cells? PLoS Biol. 2009 Mar 31; 7(3):e70. PMID: 19338386; PMCID: PMC2661962.
      View in: PubMed, PubMed Central
    38. Scott-Browne JP, White J, Kappler JW, Gapin L, Marrack P. Germline-encoded amino acids in the alphabeta T-cell receptor control thymic selection. Nature. 2009 Apr 23; 458(7241):1043-6. PMID: 19262510; PMCID: PMC2679808.
      View in: PubMed, PubMed Central
    39. Gapin L. The making of NKT cells. Nat Immunol. 2008 Sep; 9(9):1009-11. PMID: 18711440; PMCID: PMC2929952.
      View in: PubMed, PubMed Central
    40. Matsuda JL, Mallevaey T, Scott-Browne J, Gapin L. CD1d-restricted iNKT cells, the 'Swiss-Army knife' of the immune system. Curr Opin Immunol. 2008 Jun; 20(3):358-68. PMID: 18501573; PMCID: PMC2546701.
      View in: PubMed, PubMed Central
    41. Wun KS, Borg NA, Kjer-Nielsen L, Beddoe T, Koh R, Richardson SK, Thakur M, Howell AR, Scott-Browne JP, Gapin L, Godfrey DI, McCluskey J, Rossjohn J. A minimal binding footprint on CD1d-glycolipid is a basis for selection of the unique human NKT TCR. J Exp Med. 2008 Apr 14; 205(4):939-49. PMID: 18378792; PMCID: PMC2292230.
      View in: PubMed, PubMed Central
    42. Chung Y, Nurieva R, Esashi E, Wang YH, Zhou D, Gapin L, Dong C. A critical role of costimulation during intrathymic development of invariant NK T cells. J Immunol. 2008 Feb 15; 180(4):2276-83. PMID: 18250436.
      View in: PubMed
    43. Marrack P, Scott-Browne JP, Dai S, Gapin L, Kappler JW. Evolutionarily conserved amino acids that control TCR-MHC interaction. Annu Rev Immunol. 2008; 26:171-203. PMID: 18304006; PMCID: PMC3164820.
      View in: PubMed, PubMed Central
    44. Scott-Browne JP, Matsuda JL, Mallevaey T, White J, Borg NA, McCluskey J, Rossjohn J, Kappler J, Marrack P, Gapin L. Germline-encoded recognition of diverse glycolipids by natural killer T cells. Nat Immunol. 2007 Oct; 8(10):1105-13. PMID: 17828267.
      View in: PubMed
    45. Jin N, Miyahara N, Roark CL, French JD, Aydintug MK, Matsuda JL, Gapin L, O'Brien RL, Gelfand EW, Born WK. Airway hyperresponsiveness through synergy of gammadelta} T cells and NKT cells. J Immunol. 2007 Sep 01; 179(5):2961-8. PMID: 17709511; PMCID: PMC4480876.
      View in: PubMed, PubMed Central
    46. Hager E, Hawwari A, Matsuda JL, Krangel MS, Gapin L. Multiple constraints at the level of TCRalpha rearrangement impact Valpha14i NKT cell development. J Immunol. 2007 Aug 15; 179(4):2228-34. PMID: 17675483.
      View in: PubMed
    47. Joshi NS, Cui W, Chandele A, Lee HK, Urso DR, Hagman J, Gapin L, Kaech SM. Inflammation directs memory precursor and short-lived effector CD8(+) T cell fates via the graded expression of T-bet transcription factor. Immunity. 2007 Aug; 27(2):281-95. PMID: 17723218; PMCID: PMC2034442.
      View in: PubMed, PubMed Central
    48. Kronenberg M, Gapin L. Natural killer T cells: know thyself. Proc Natl Acad Sci U S A. 2007 Apr 03; 104(14):5713-4. PMID: 17389403; PMCID: PMC1851556.
      View in: PubMed, PubMed Central
    49. Matsuda JL, George TC, Hagman J, Gapin L. Temporal dissection of T-bet functions. J Immunol. 2007 Mar 15; 178(6):3457-65. PMID: 17339440.
      View in: PubMed
    50. Matsuda JL, Gapin L. Does the developmental status of Valpha14i NKT cells play a role in disease? Int Rev Immunol. 2007 Jan-Apr; 26(1-2):5-29. PMID: 17454262.
      View in: PubMed
    51. Matsuda JL, Zhang Q, Ndonye R, Richardson SK, Howell AR, Gapin L. T-bet concomitantly controls migration, survival, and effector functions during the development of Valpha14i NKT cells. Blood. 2006 Apr 01; 107(7):2797-805. PMID: 16357323; PMCID: PMC1895373.
      View in: PubMed, PubMed Central
    52. Intlekofer AM, Takemoto N, Wherry EJ, Longworth SA, Northrup JT, Palanivel VR, Mullen AC, Gasink CR, Kaech SM, Miller JD, Gapin L, Ryan K, Russ AP, Lindsten T, Orange JS, Goldrath AW, Ahmed R, Reiner SL. Effector and memory CD8+ T cell fate coupled by T-bet and eomesodermin. Nat Immunol. 2005 Dec; 6(12):1236-44. PMID: 16273099.
      View in: PubMed
    53. Matsuda JL, Gapin L. Developmental program of mouse Valpha14i NKT cells. Curr Opin Immunol. 2005 Apr; 17(2):122-30. PMID: 15766670.
      View in: PubMed
    54. Faure M, Gapin L, Viret C. Stressing the virtues of the immune system. Microbes Infect. 2004 Aug; 6(10):960-4. PMID: 15332301.
      View in: PubMed
    55. Townsend MJ, Weinmann AS, Matsuda JL, Salomon R, Farnham PJ, Biron CA, Gapin L, Glimcher LH. T-bet regulates the terminal maturation and homeostasis of NK and Valpha14i NKT cells. Immunity. 2004 Apr; 20(4):477-94. PMID: 15084276.
      View in: PubMed
    56. Stetson DB, Mohrs M, Reinhardt RL, Baron JL, Wang ZE, Gapin L, Kronenberg M, Locksley RM. Constitutive cytokine mRNAs mark natural killer (NK) and NK T cells poised for rapid effector function. J Exp Med. 2003 Oct 06; 198(7):1069-76. PMID: 14530376; PMCID: PMC2194220.
      View in: PubMed, PubMed Central
    57. Matsuda JL, Gapin L, Baron JL, Sidobre S, Stetson DB, Mohrs M, Locksley RM, Kronenberg M. Mouse V alpha 14i natural killer T cells are resistant to cytokine polarization in vivo. Proc Natl Acad Sci U S A. 2003 Jul 08; 100(14):8395-400. PMID: 12829795; PMCID: PMC166240.
      View in: PubMed, PubMed Central
    58. Chun T, Page MJ, Gapin L, Matsuda JL, Xu H, Nguyen H, Kang HS, Stanic AK, Joyce S, Koltun WA, Chorney MJ, Kronenberg M, Wang CR. CD1d-expressing dendritic cells but not thymic epithelial cells can mediate negative selection of NKT cells. J Exp Med. 2003 Apr 07; 197(7):907-18. PMID: 12682110; PMCID: PMC2193895.
      View in: PubMed, PubMed Central
    59. Matsuda JL, Gapin L, Sidobre S, Kieper WC, Tan JT, Ceredig R, Surh CD, Kronenberg M. Homeostasis of V alpha 14i NKT cells. Nat Immunol. 2002 Oct; 3(10):966-74. PMID: 12244311.
      View in: PubMed
    60. Kronenberg M, Gapin L. The unconventional lifestyle of NKT cells. Nat Rev Immunol. 2002 Aug; 2(8):557-68. PMID: 12154375.
      View in: PubMed
    61. Kieper WC, Tan JT, Bondi-Boyd B, Gapin L, Sprent J, Ceredig R, Surh CD. Overexpression of interleukin (IL)-7 leads to IL-15-independent generation of memory phenotype CD8+ T cells. J Exp Med. 2002 Jun 17; 195(12):1533-9. PMID: 12070281; PMCID: PMC2193553.
      View in: PubMed, PubMed Central
    62. Takahashi I, Matsuda J, Gapin L, DeWinter H, Kai Y, Tamagawa H, Kronenberg M, Kiyono H. Colitis-related public T cells are selected in the colonic lamina propria of IL-10-deficient mice. Clin Immunol. 2002 Mar; 102(3):237-48. PMID: 11890710.
      View in: PubMed
    63. Leishman AJ, Gapin L, Capone M, Palmer E, MacDonald HR, Kronenberg M, Cheroutre H. Precursors of functional MHC class I- or class II-restricted CD8alphaalpha(+) T cells are positively selected in the thymus by agonist self-peptides. Immunity. 2002 Mar; 16(3):355-64. PMID: 11911821.
      View in: PubMed
    64. Ebhardt MB, Shive CL, Guardia R, Gapin L, Boehm BO, Forsthuber TG. Immunological adjuvants efficiently induce antigen-specific T cell responses in old mice: implications for vaccine adjuvant development in aged individuals. Cell Immunol. 2002 Jan; 215(1):87-97. PMID: 12142040.
      View in: PubMed
    65. Matsuda JL, Gapin L, Fazilleau N, Warren K, Naidenko OV, Kronenberg M. Natural killer T cells reactive to a single glycolipid exhibit a highly diverse T cell receptor beta repertoire and small clone size. Proc Natl Acad Sci U S A. 2001 Oct 23; 98(22):12636-41. PMID: 11592984; PMCID: PMC60106.
      View in: PubMed, PubMed Central
    66. Gapin L, Matsuda JL, Surh CD, Kronenberg M. NKT cells derive from double-positive thymocytes that are positively selected by CD1d. Nat Immunol. 2001 Oct; 2(10):971-8. PMID: 11550008.
      View in: PubMed
    67. Matsuda JL, Naidenko OV, Gapin L, Nakayama T, Taniguchi M, Wang CR, Koezuka Y, Kronenberg M. Tracking the response of natural killer T cells to a glycolipid antigen using CD1d tetramers. J Exp Med. 2000 Sep 04; 192(5):741-54. PMID: 10974039; PMCID: PMC2193268.
      View in: PubMed, PubMed Central
    68. Matsuda JL, Gapin L, Sydora BC, Byrne F, Binder S, Kronenberg M, Aranda R. Systemic activation and antigen-driven oligoclonal expansion of T cells in a mouse model of colitis. J Immunol. 2000 Mar 01; 164(5):2797-806. PMID: 10679123.
      View in: PubMed
    69. Foucras G, Gapin L, Coureau C, Kanellopoulos JM, Guéry JC. Interleukin 4-producing CD4 T cells arise from different precursors depending on the conditions of antigen exposure in vivo. J Exp Med. 2000 Feb 21; 191(4):683-94. PMID: 10684860; PMCID: PMC2195842.
      View in: PubMed, PubMed Central
    70. Gapin L, Cheroutre H, Kronenberg M. Cutting edge: TCR alpha beta+ CD8 alpha alpha+ T cells are found in intestinal intraepithelial lymphocytes of mice that lack classical MHC class I molecules. J Immunol. 1999 Oct 15; 163(8):4100-4. PMID: 10510343.
      View in: PubMed
    71. Gapin L, Fukui Y, Kanellopoulos J, Sano T, Casrouge A, Malier V, Beaudoing E, Gautheret D, Claverie JM, Sasazuki T, Kourilsky P. Quantitative analysis of the T cell repertoire selected by a single peptide-major histocompatibility complex. J Exp Med. 1998 Jun 01; 187(11):1871-83. PMID: 9607927; PMCID: PMC2212317.
      View in: PubMed, PubMed Central
    72. Amigorena S, Lankar D, Briken V, Gapin L, Viguier M, Bonnerot C. Type II and III receptors for immunoglobulin G (IgG) control the presentation of different T cell epitopes from single IgG-complexed antigens. J Exp Med. 1998 Feb 16; 187(4):505-15. PMID: 9463401; PMCID: PMC2212157.
      View in: PubMed, PubMed Central
    73. Gapin L, Bravo de Alba Y, Casrouge A, Cabaniols JP, Kourilsky P, Kanellopoulos J. Antigen presentation by dendritic cells focuses T cell responses against immunodominant peptides: studies in the hen egg-white lysozyme (HEL) model. J Immunol. 1998 Feb 15; 160(4):1555-64. PMID: 9469410.
      View in: PubMed
    74. Kourilsky P, Bousso P, Calbo S, Gapin L. Immunological issues in vaccine trials: T-cell responses. Dev Biol Stand. 1998; 95:117-24. PMID: 9855421.
      View in: PubMed
    75. Gapin L, Cabaniols JP, Cibotti R, Ojcius DM, Kourilsky P, Kanellopoulos JM. Determinant selection for T-cell tolerance in HEL-transgenic mice: dissociation between immunogenicity and tolerogenicity. Cell Immunol. 1997 Apr 10; 177(1):77-85. PMID: 9140098.
      View in: PubMed
    76. Ojcius DM, Gapin L, Kanellopoulos JM, Kourilsky P. Is antigen processing guided by major histocompatibility complex molecules? FASEB J. 1994 Sep; 8(12):974-8. PMID: 8088463.
      View in: PubMed
    77. Ojcius DM, Gapin L, Kourilsky P. Dissociation of the peptide/MHC class I complex: pH dependence and effect of endogenous peptides on the activation energy. Biochem Biophys Res Commun. 1993 Dec 30; 197(3):1216-22. PMID: 8280136.
      View in: PubMed
    Gapin's Networks
    Click the "See All" links for more information and interactive visualizations!
    Concepts Expand Description
    See all (282) concept(s)
    _
    Co-Authors Expand Description
    See all (19) people
    _
    Similar People Expand Description
    See all (60) people
    _
    Same Department Expand Description
    Search Department
    Physical Neighbors Expand Description
    _

    Copyright © 2017 The Regents of the University of Colorado, a body corporate. All rights reserved. (Harvard PROFILES RNS software version: 2.10.0)