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Daniel K. Schwartz

TitleProfessor
InstitutionUniversity of Colorado Boulder
DepartmentChemical & Biological Engin
Phone303/735-0240
    Other Positions
    TitleAssoc Chair
    InstitutionUniversity of Colorado Boulder
    DepartmentChemical & Biological Engin


    Collapse Research 
    Collapse research activities and funding
    R21EB015061     (SCHWARTZ, DANIEL)Apr 1, 2012 - Mar 31, 2014
    NIH/NIBIB
    Effects of Vicinal Surface Chemistry on DNA Base-Pairing using Single-Molecule RE
    Role: Principal Investigator
    R21EB015532     (SCHWARTZ, DANIEL)Aug 1, 2012 - Jul 31, 2014
    NIH/NIBIB
    Tools to Connect Protein Conformations, Dynamics, and Associations
    Role: Principal Investigator

    Collapse Bibliographic 
    Collapse selected publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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    1. Kastantin M, Faulón Marruecos D, Grover N, Yu McLoughlin S, Schwartz DK, Kaar JL. Connecting Protein Conformation and Dynamics with Ligand-Receptor Binding Using Three-Color Förster Resonance Energy Transfer Tracking. J Am Chem Soc. 2017 Jul 12. PMID: 28658579.
      View in: PubMed
    2. Cai Y, Shashikanth N, Leckband DE, Schwartz DK. Cadherin Diffusion in Supported Lipid Bilayers Exhibits Calcium-Dependent Dynamic Heterogeneity. Biophys J. 2016 Dec 20; 111(12):2658-2665. PMID: 28002742.
      View in: PubMed
    3. Sorret LL, DeWinter MA, Schwartz DK, Randolph TW. Challenges in Predicting Protein-Protein Interactions from Measurements of Molecular Diffusivity. Biophys J. 2016 Nov 01; 111(9):1831-1842. PMID: 27806265.
      View in: PubMed
    4. Monserud JH, Macri KM, Schwartz DK. Toehold-Mediated Displacement of an Adenosine-Binding Aptamer from a DNA Duplex by its Ligand. Angew Chem Int Ed Engl. 2016 Oct 24; 55(44):13710-13713. PMID: 27689920.
      View in: PubMed
    5. Monserud JH, Schwartz DK. Interfacial Molecular Searching Using Forager Dynamics. Phys Rev Lett. 2016 Mar 04; 116(9):098303. PMID: 26991206.
      View in: PubMed
    6. Faulón Marruecos D, Kastantin M, Schwartz DK, Kaar JL. Dense Poly(ethylene glycol) Brushes Reduce Adsorption and Stabilize the Unfolded Conformation of Fibronectin. Biomacromolecules. 2016 Mar 14; 17(3):1017-25. PMID: 26866385.
      View in: PubMed
    7. Cai Y, Schwartz DK. Influence of Protein Surface Coverage on Anomalously Strong Adsorption Sites. ACS Appl Mater Interfaces. 2016 Jan 13; 8(1):511-20. PMID: 26651508.
      View in: PubMed
    8. Weltz JS, Schwartz DK, Kaar JL. Surface-Mediated Protein Unfolding as a Search Process for Denaturing Sites. ACS Nano. 2016 Jan 26; 10(1):730-8. PMID: 26580418; PMCID: PMC4729621 [Available on 01/26/17].
      View in: PubMed, PubMed Central
    9. Chakraborty S, Noonan PS, Monserud J, Schwartz DK. Structure-Specific Liquid Crystal Anchoring Induced by the Molecular Combing of Short Oligonucleotides. ACS Appl Mater Interfaces. 2015 Dec 09; 7(48):26874-9. PMID: 26562585.
      View in: PubMed
    10. Gerhardt A, Mcumber AC, Nguyen BH, Lewus R, Schwartz DK, Carpenter JF, Randolph TW. Surfactant Effects on Particle Generation in Antibody Formulations in Pre-filled Syringes. J Pharm Sci. 2015 Dec; 104(12):4056-64. PMID: 26413998; PMCID: PMC4804708 [Available on 12/01/16].
      View in: PubMed, PubMed Central
    11. Wang D, Hu R, Mabry JN, Miao B, Wu DT, Koynov K, Schwartz DK. Scaling of polymer dynamics at an oil-water interface in regimes dominated by viscous drag and desorption-mediated flights. J Am Chem Soc. 2015 Sep 30; 137(38):12312-20. PMID: 26348667.
      View in: PubMed
    12. Langdon BB, Kastantin M, Schwartz DK. Surface Chemistry Influences Interfacial Fibrinogen Self-Association. Biomacromolecules. 2015 Oct 12; 16(10):3201-8. PMID: 26327275.
      View in: PubMed
    13. Macri KM, Noonan PS, Schwartz DK. Receptor-Mediated Liposome Fusion Kinetics at Aqueous/Liquid Crystal Interfaces. ACS Appl Mater Interfaces. 2015 Sep 16; 7(36):20400-9. PMID: 26317496.
      View in: PubMed
    14. Chakraborty S, Nelson N, Schwartz DK. Anisotropic molecular hopping at the solid-nematic interface. Soft Matter. 2015 Oct 21; 11(39):7712-6. PMID: 26313353.
      View in: PubMed
    15. McUmber AC, Randolph TW, Schwartz DK. Electrostatic Interactions Influence Protein Adsorption (but Not Desorption) at the Silica-Aqueous Interface. J Phys Chem Lett. 2015 Jul 02; 6(13):2583-7. PMID: 26266737.
      View in: PubMed
    16. Mabry JN, Kastantin M, Schwartz DK. Capturing Conformation-Dependent Molecule-Surface Interactions When Surface Chemistry Is Heterogeneous. ACS Nano. 2015 Jul 28; 9(7):7237-47. PMID: 26079177.
      View in: PubMed
    17. Nelson N, Schwartz DK. Unbiased Clustering of Molecular Dynamics for Spatially Resolved Analysis of Chemically Heterogeneous Surfaces. Langmuir. 2015 Jun 09; 31(22):6099-106. PMID: 26001158.
      View in: PubMed
    18. Mabry JN, Schwartz DK. Tuning the Flight Length of Molecules Diffusing on a Hydrophobic Surface. J Phys Chem Lett. 2015 Jun 04; 6(11):2065-9. PMID: 26266503.
      View in: PubMed
    19. McUmber AC, Larson NR, Randolph TW, Schwartz DK. Molecular trajectories provide signatures of protein clustering and crowding at the oil/water interface. Langmuir. 2015 Jun 02; 31(21):5882-90. PMID: 25950404.
      View in: PubMed
    20. Skaug MJ, Wang L, Ding Y, Schwartz DK. Hindered nanoparticle diffusion and void accessibility in a three-dimensional porous medium. ACS Nano. 2015 Feb 24; 9(2):2148-56. PMID: 25647084.
      View in: PubMed
    21. Langdon BB, Mirhossaini RB, Mabry JN, Sriram I, Lajmi A, Zhang Y, Rojas OJ, Schwartz DK. Single-molecule resolution of protein dynamics on polymeric membrane surfaces: the roles of spatial and population heterogeneity. ACS Appl Mater Interfaces. 2015 Feb 18; 7(6):3607-17. PMID: 25611782.
      View in: PubMed
    22. Wang D, He C, Stoykovich MP, Schwartz DK. Nanoscale topography influences polymer surface diffusion. ACS Nano. 2015 Feb 24; 9(2):1656-64. PMID: 25621372.
      View in: PubMed
    23. Wang D, Hu R, Skaug MJ, Schwartz DK. Temporally Anticorrelated Motion of Nanoparticles at a Liquid Interface. J Phys Chem Lett. 2015 Jan 02; 6(1):54-9. PMID: 26263091.
      View in: PubMed
    24. Mabry JN, Skaug MJ, Schwartz DK. Single-molecule insights into retention at a reversed-phase chromatographic interface. Anal Chem. 2014 Oct 07; 86(19):9451-8. PMID: 25188676.
      View in: PubMed
    25. Noonan PS, Mohan P, Goodwin AP, Schwartz DK. DNA Hybridization-Mediated Liposome Fusion at the Aqueous Liquid Crystal Interface. Adv Funct Mater. 2014 Jun 04; 24(21):3206-3212. PMID: 25506314.
      View in: PubMed
    26. Gerhardt A, Mcgraw NR, Schwartz DK, Bee JS, Carpenter JF, Randolph TW. Protein aggregation and particle formation in prefilled glass syringes. J Pharm Sci. 2014 Jun; 103(6):1601-12. PMID: 24729310.
      View in: PubMed
    27. Monserud JH, Schwartz DK. Mechanisms of surface-mediated DNA hybridization. ACS Nano. 2014 May 27; 8(5):4488-99. PMID: 24708278; PMCID: PMC4046783.
      View in: PubMed, PubMed Central
    28. Schoenbaum CA, Schwartz DK, Medlin JW. Controlling the surface environment of heterogeneous catalysts using self-assembled monolayers. Acc Chem Res. 2014 Apr 15; 47(4):1438-45. PMID: 24635215.
      View in: PubMed
    29. Skaug MJ, Lacasta AM, Ramirez-Piscina L, Sancho JM, Lindenberg K, Schwartz DK. Single-molecule diffusion in a periodic potential at a solid-liquid interface. Soft Matter. 2014 Feb 07; 10(5):753-9. PMID: 24837682.
      View in: PubMed
    30. Kastantin M, Langdon BB, Schwartz DK. A bottom-up approach to understanding protein layer formation at solid-liquid interfaces. Adv Colloid Interface Sci. 2014 May; 207:240-52. PMID: 24484895; PMCID: PMC4028386.
      View in: PubMed, PubMed Central
    31. Kahsar KR, Schwartz DK, Medlin JW. Control of metal catalyst selectivity through specific noncovalent molecular interactions. J Am Chem Soc. 2014 Jan 08; 136(1):520-6. PMID: 24320969.
      View in: PubMed
    32. Skaug MJ, Coffey BM, Schwartz DK. Colloidal transfer printing. ACS Appl Mater Interfaces. 2013 Dec 26; 5(24):12854-9. PMID: 24274697.
      View in: PubMed
    33. Langdon BB, Kastantin M, Walder R, Schwartz DK. Interfacial protein-protein associations. Biomacromolecules. 2014 Jan 13; 15(1):66-74. PMID: 24274729; PMCID: PMC3895929.
      View in: PubMed, PubMed Central
    34. Skaug MJ, Mabry JN, Schwartz DK. Single-molecule tracking of polymer surface diffusion. J Am Chem Soc. 2014 Jan 29; 136(4):1327-32. PMID: 24266657.
      View in: PubMed
    35. McLoughlin SY, Kastantin M, Schwartz DK, Kaar JL. Single-molecule resolution of protein structure and interfacial dynamics on biomaterial surfaces. Proc Natl Acad Sci U S A. 2013 Nov 26; 110(48):19396-401. PMID: 24235137; PMCID: PMC3845135.
      View in: PubMed, PubMed Central
    36. Skaug MJ, Mabry J, Schwartz DK. Intermittent molecular hopping at the solid-liquid interface. Phys Rev Lett. 2013 Jun 21; 110(25):256101. PMID: 23829747.
      View in: PubMed
    37. Liu L, Qi W, Schwartz DK, Randolph TW, Carpenter JF. The effects of excipients on protein aggregation during agitation: an interfacial shear rheology study. J Pharm Sci. 2013 Aug; 102(8):2460-70. PMID: 23712900; PMCID: PMC4174554.
      View in: PubMed, PubMed Central
    38. Noonan PS, Roberts RH, Schwartz DK. Liquid crystal reorientation induced by aptamer conformational changes. J Am Chem Soc. 2013 Apr 03; 135(13):5183-9. PMID: 23510322.
      View in: PubMed
    39. Pang SH, Schoenbaum CA, Schwartz DK, Medlin JW. Directing reaction pathways by catalyst active-site selection using self-assembled monolayers. Nat Commun. 2013; 4:2448. PMID: 24025780.
      View in: PubMed
    40. Kastantin M, Schwartz DK. Identifying multiple populations from single-molecule lifetime distributions. Chemphyschem. 2013 Feb 04; 14(2):374-80. PMID: 23255328.
      View in: PubMed
    41. Jamison AC, Zhang S, Zenasni O, Schwartz DK, Lee TR. Fibrillar self-organization of a line-active partially fluorinated thiol within binary self-assembled monolayers. Langmuir. 2012 Dec 11; 28(49):16834-44. PMID: 23140360.
      View in: PubMed
    42. Kastantin M, Schwartz DK. DNA hairpin stabilization on a hydrophobic surface. Small. 2013 Mar 25; 9(6):933-41. PMID: 23184340; PMCID: PMC3741999.
      View in: PubMed, PubMed Central
    43. Monserud JH, Schwartz DK. Effects of molecular size and surface hydrophobicity on oligonucleotide interfacial dynamics. Biomacromolecules. 2012 Dec 10; 13(12):4002-11. PMID: 23127250; PMCID: PMC3518566.
      View in: PubMed, PubMed Central
    44. Sriram I, Singhana B, Lee TR, Schwartz DK. Line tension and line activity in mixed monolayers composed of aliphatic and terphenyl-containing surfactants. Langmuir. 2012 Nov 27; 28(47):16294-9. PMID: 23101697.
      View in: PubMed
    45. Britt KA, Schwartz DK, Wurth C, Mahler HC, Carpenter JF, Randolph TW. Excipient effects on humanized monoclonal antibody interactions with silicone oil emulsions. J Pharm Sci. 2012 Dec; 101(12):4419-32. PMID: 22987313.
      View in: PubMed
    46. Nelson N, Walder R, Schwartz DK. Single molecule dynamics on hydrophobic self-assembled monolayers. Langmuir. 2012 Aug 21; 28(33):12108-13. PMID: 22876990.
      View in: PubMed
    47. Kastantin M, Schwartz DK. Distinguishing positional uncertainty from true mobility in single-molecule trajectories that exhibit multiple diffusive modes. Microsc Microanal. 2012 Aug; 18(4):793-7. PMID: 22849801; PMCID: PMC3410552.
      View in: PubMed, PubMed Central
    48. Kastantin M, Walder R, Schwartz DK. Identifying mechanisms of interfacial dynamics using single-molecule tracking. Langmuir. 2012 Aug 28; 28(34):12443-56. PMID: 22716995; PMCID: PMC3429661.
      View in: PubMed, PubMed Central
    49. Langdon BB, Kastantin M, Schwartz DK. Apparent activation energies associated with protein dynamics on hydrophobic and hydrophilic surfaces. Biophys J. 2012 Jun 06; 102(11):2625-33. PMID: 22713578; PMCID: PMC3368127.
      View in: PubMed, PubMed Central
    50. Walder R, Kastantin M, Schwartz DK. High throughput single molecule tracking for analysis of rare populations and events. Analyst. 2012 Jul 07; 137(13):2987-96. PMID: 22617120.
      View in: PubMed
    51. Walder R, Nelson N, Schwartz DK. Super-resolution surface mapping using the trajectories of molecular probes. Nat Commun. 2011 Nov 01; 2:515. PMID: 22044994.
      View in: PubMed
    52. Noonan PS, Shavit A, Acharya BR, Schwartz DK. Mixed alkylsilane functionalized surfaces for simultaneous wetting and homeotropic anchoring of liquid crystals. ACS Appl Mater Interfaces. 2011 Nov; 3(11):4374-80. PMID: 22003870.
      View in: PubMed
    53. Walder R, Nelson N, Schwartz DK. Single molecule observations of desorption-mediated diffusion at the solid-liquid interface. Phys Rev Lett. 2011 Oct 07; 107(15):156102. PMID: 22107306.
      View in: PubMed
    54. Kastantin M, Schwartz DK. Connecting rare DNA conformations and surface dynamics using single-molecule resonance energy transfer. ACS Nano. 2011 Dec 27; 5(12):9861-9. PMID: 21942411; PMCID: PMC3246573.
      View in: PubMed, PubMed Central
    55. Malone SM, Schwartz DK. Macroscopic liquid crystal response to isolated DNA helices. Langmuir. 2011 Oct 04; 27(19):11767-72. PMID: 21894894.
      View in: PubMed
    56. Marshall ST, Schwartz DK, Medlin JW. Adsorption of oxygenates on alkanethiol-functionalized Pd(111) surfaces: mechanistic insights into the role of self-assembled monolayers on catalysis. Langmuir. 2011 Jun 07; 27(11):6731-7. PMID: 21526824.
      View in: PubMed
    57. Kastantin M, Langdon BB, Chang EL, Schwartz DK. Single-molecule resolution of interfacial fibrinogen behavior: effects of oligomer populations and surface chemistry. J Am Chem Soc. 2011 Apr 06; 133(13):4975-83. PMID: 21391676; PMCID: PMC3077424.
      View in: PubMed, PubMed Central
    58. Marshall ST, O'Brien M, Oetter B, Corpuz A, Richards RM, Schwartz DK, Medlin JW. Controlled selectivity for palladium catalysts using self-assembled monolayers. Nat Mater. 2010 Oct; 9(10):853-8. PMID: 20835234.
      View in: PubMed
    59. Walder RB, Honciuc A, Schwartz DK. Phospholipid diffusion at the oil-water interface. J Phys Chem B. 2010 Sep 09; 114(35):11484-8. PMID: 20707362.
      View in: PubMed
    60. Walder R, Schwartz DK. Single molecule observations of multiple protein populations at the oil-water interface. Langmuir. 2010 Aug 17; 26(16):13364-7. PMID: 20695579.
      View in: PubMed
    61. Malone SM, Trabelsi S, Zhang S, Lee TR, Schwartz DK. Self-assembly of linactants: micelles and lyotropic liquid crystals in two dimensions. J Phys Chem B. 2010 Jul 08; 114(26):8616-20. PMID: 20553014.
      View in: PubMed
    62. Walder R, Honciuc A, Schwartz DK. Directed nanoparticle motion on an interfacial free energy gradient. Langmuir. 2010 Feb 02; 26(3):1501-3. PMID: 20000390.
      View in: PubMed
    63. Trabelsi S, Zhang Z, Zhang S, Lee TR, Schwartz DK. Correlating linactant efficiency and self-assembly: structural basis of line activity in molecular monolayers. Langmuir. 2009 Jul 21; 25(14):8056-61. PMID: 19594183.
      View in: PubMed
    64. Honciuc A, Baptiste DJ, Campbell IP, Schwartz DK. Solvent dependence of the activation energy of attachment determined by single molecule observations of surfactant adsorption. Langmuir. 2009 Jul 07; 25(13):7389-92. PMID: 19563226.
      View in: PubMed
    65. Honciuc A, Schwartz DK. Probing hydrophobic interactions using trajectories of amphiphilic molecules at a hydrophobic/water interface. J Am Chem Soc. 2009 Apr 29; 131(16):5973-9. PMID: 19338306.
      View in: PubMed
    66. Honciuc A, Baptiste DJ, Schwartz DK. Hydrophobic interaction microscopy: mapping the solid/ liquid interface using amphiphilic probe molecules. Langmuir. 2009 Apr 21; 25(8):4339-42. PMID: 19253960.
      View in: PubMed
    67. Zhang S, Jamison AC, Schwartz DK, Lee TR. Self-assembled monolayers derived from a double-chained monothiol having chemically dissimilar chains. Langmuir. 2008 Sep 16; 24(18):10204-8. PMID: 18698870.
      View in: PubMed
    68. Malone SM, Schwartz DK. Polar and azimuthal alignment of a nematic liquid crystal by alkylsilane self-assembled monolayers: effects of chain-length and mechanical rubbing. Langmuir. 2008 Sep 02; 24(17):9790-4. PMID: 18686979.
      View in: PubMed
    69. Price AD, Schwartz DK. DNA hybridization-induced reorientation of liquid crystal anchoring at the nematic liquid crystal/aqueous interface. J Am Chem Soc. 2008 Jul 02; 130(26):8188-94. PMID: 18528984.
      View in: PubMed
    70. Honciuc A, Harant AW, Schwartz DK. Single-molecule observations of surfactant diffusion at the solution-solid interface. Langmuir. 2008 Jun 01; 24(13):6562-6. PMID: 18489129.
      View in: PubMed
    71. Trabelsi S, Zhang S, Lee TR, Schwartz DK. Linactants: surfactant analogues in two dimensions. Phys Rev Lett. 2008 Jan 25; 100(3):037802. PMID: 18233038.
      View in: PubMed
    72. Karp E, Pecinovsky CS, McNevin MJ, Gin DL, Schwartz DK. Langmuir monolayers of a photoisomerizable macrocycle surfactant. Langmuir. 2007 Jul 17; 23(15):7923-7. PMID: 17583924.
      View in: PubMed
    73. Forward KM, Moster AL, Schwartz DK, Lacks DJ. Contact angles of submillimeter particles: connecting wettability to nanoscale surface topography. Langmuir. 2007 May 08; 23(10):5255-8. PMID: 17402768.
      View in: PubMed
    74. Price AD, Schwartz DK. Fatty-acid monolayers at the nematic/water interface: phases and liquid-crystal alignment. J Phys Chem B. 2007 Feb 08; 111(5):1007-15. PMID: 17266255.
      View in: PubMed
    75. Cain N, Van Bogaert J, Gin DL, Hammond SR, Schwartz DK. Self-organization of a wedge-shaped surfactant in monolayers and multilayers. Langmuir. 2007 Jan 16; 23(2):482-7. PMID: 17209597.
      View in: PubMed
    76. Price AD, Schwartz DK. Anchoring of a nematic liquid crystal on a wettability gradient. Langmuir. 2006 Nov 07; 22(23):9753-9. PMID: 17073507.
      View in: PubMed
    77. Vessely CR, Carpenter JF, Schwartz DK. Calcium-induced changes to the molecular conformation and aggregate structure of beta-casein at the air-water interface. Biomacromolecules. 2005 Nov-Dec; 6(6):3334-44. PMID: 16283763.
      View in: PubMed
    78. Nelson M, Cain N, Taylor CE, Ocko BM, Gin DL, Hammond SR, Schwartz DK. Periodic arrays of interfacial cylindrical reverse micelles. Langmuir. 2005 Oct 25; 21(22):9799-802. PMID: 16229494.
      View in: PubMed
    79. Bantchev GB, Schwartz DK. Structure of beta-casein layers at the air/solution interface: atomic force microscopy studies of transferred layers. Langmuir. 2004 Dec 21; 20(26):11692-7. PMID: 15595799.
      View in: PubMed
    80. Mellott JM, Schwartz DK. Supercritical self-assembled monolayer growth. J Am Chem Soc. 2004 Aug 04; 126(30):9369-73. PMID: 15281828.
      View in: PubMed
    81. Mellott JM, Hayes WA, Schwartz DK. Kinetics of octadecyltrimethylammonium bromide self-assembled monolayer growth at mica from an aqueous solution. Langmuir. 2004 Mar 16; 20(6):2341-8. PMID: 15835694.
      View in: PubMed
    82. Simmons BA, Taylor CE, Landis FA, John VT, McPherson GL, Schwartz DK, Moore R. Microstructure determination of AOT + phenol organogels utilizing small-angle X-ray scattering and atomic force microscopy. J Am Chem Soc. 2001 Mar 14; 123(10):2414-21. PMID: 11456891.
      View in: PubMed
    83. Schwartz DK. Mechanisms and kinetics of self-assembled monolayer formation. Annu Rev Phys Chem. 2001; 52:107-37. PMID: 11326061.
      View in: PubMed
    84. Ignés-Mullol J, Schwartz DK. Alignment of hexatic langmuir monolayers under shear. Phys Rev Lett. 2000 Aug 14; 85(7):1476-9. PMID: 10970533.
      View in: PubMed
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