Colorado PROFILES, The Colorado Clinical and Translational Sciences Institute (CCTSI)
Keywords
Last Name
Institution
Menu

Contact Us
If you have any questions or feedback please contact us.

Dwight J. Klemm

TitleProfessor
InstitutionUniversity of Colorado Denver - Anschutz Medical Campus
DepartmentSOM-MED
Phone303/724-3686

    Collapse Research 
    Collapse research activities and funding
    I01BX005135     (KLEMM, DWIGHT J)Apr 1, 2021 - Mar 31, 2025
    NIH
    Diminished Sex Hormone Levels Stimulate Production of Inflammatory Bone Marrow-Derived Adipocytes
    Role: Principal Investigator
    R01DK109547     (KLEMM, DWIGHT J)Apr 1, 2016 - Jan 31, 2021
    NIH
    Integrin signaling promotes production of adipocytes from hematopoietic cells
    Role: Principal Investigator
    I21CX001341     (KLEMM, DWIGHT J)Apr 1, 2016 - Mar 31, 2018
    NIH
    Age- and Sex-associated Production of Adipocytes from Bone Marrow Stem Cells
    Role: Principal Investigator
    R56DK078966     (KLEMM, DWIGHT J)Aug 17, 2007 - Jul 31, 2008
    NIH
    A Novel Adipocyte Population Arises From Bone Marrow Progenitor Cells
    Role: Principal Investigator
    R01DK078966     (KLEMM, DWIGHT J)Jul 1, 2007 - May 31, 2018
    NIH
    A Novel Adipocyte Population Arises From Bone Marrow Progenitor Cells
    Role: Principal Investigator
    R01DK053969     (KLEMM, DWIGHT J)Aug 1, 1998 - Jun 30, 2014
    NIH
    CREB Regulates Adipogenesis and Adipocyte Survival
    Role: Principal Investigator
    R29GM047117     (KLEMM, DWIGHT J)Aug 1, 1993 - Jul 31, 1998
    NIH
    REGULATION OF CREB/ATF FUNCTION BY PROTEIN PHOSPHATASES
    Role: Principal Investigator

    Collapse Bibliographic 
    Collapse selected publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
    List All   |   Timeline
    1. Gavin KM, Sullivan TM, Maltzahn JK, Jackman MR, Libby AE, MacLean PS, Kohrt WM, Majka SM, Klemm DJ. Hematopoietic Stem Cell-Derived Adipocytes Modulate Adipose Tissue Cellularity, Leptin Production and Insulin Responsiveness in Female Mice. Front Endocrinol (Lausanne). 2022; 13:844877. PMID: 35721743.
      View in: PubMed
    2. Gavin KM, Sullivan TM, Maltzahn JK, Rahkola JT, Acosta AS, Kohrt WM, Majka SM, Klemm DJ. Hematopoietic stem cells produce intermediate lineage adipocyte progenitors that simultaneously express both myeloid and mesenchymal lineage markers in adipose tissue. Adipocyte. 2021 12; 10(1):394-407. PMID: 34404315.
      View in: PubMed
    3. Strassheim D, Sullivan T, Irwin DC, Gerasimovskaya E, Lahm T, Klemm DJ, Dempsey EC, Stenmark KR, Karoor V. Metabolite G-Protein Coupled Receptors in Cardio-Metabolic Diseases. Cells. 2021 11 29; 10(12). PMID: 34943862.
      View in: PubMed
    4. Summers ME, Richmond BW, Menon S, Sheridan RM, Kropski JA, Majka SA, Taketo MM, Bastarache JA, West JD, De Langhe S, Geraghty P, Klemm DJ, Chu HW, Friedman RS, Tao YK, Foronjy RF, Majka SM. Resident mesenchymal vascular progenitors modulate adaptive angiogenesis and pulmonary remodeling via regulation of canonical Wnt signaling. FASEB J. 2020 08; 34(8):10267-10285. PMID: 32533805.
      View in: PubMed
    5. Garat CV, Majka SM, Sullivan TM, Crossno JT, Reusch JEB, Klemm DJ. CREB depletion in smooth muscle cells promotes medial thickening, adventitial fibrosis and elicits pulmonary hypertension. Pulm Circ. 2020 Apr-Jun; 10(2):2045894019898374. PMID: 32313640.
      View in: PubMed
    6. Gewin LS, Summers ME, Harral JW, Gaskill CF, Khodo SN, Neelisetty S, Sullivan TM, Hopp K, Reese JJ, Klemm DJ, Kon V, Ess KC, Shi W, Majka SM. Inactivation of Tsc2 in Abcg2 lineage-derived cells drives the appearance of polycystic lesions and fibrosis in the adult kidney. Am J Physiol Renal Physiol. 2019 11 01; 317(5):F1201-F1210. PMID: 31461347.
      View in: PubMed
    7. Gavin KM, Kohrt WM, Klemm DJ, Melanson EL. Modulation of Energy Expenditure by Estrogens and Exercise in Women. Exerc Sport Sci Rev. 2018 10; 46(4):232-239. PMID: 30001272.
      View in: PubMed
    8. Gavin KM, Sullivan TM, Kohrt WM, Majka SM, Klemm DJ. Ovarian Hormones Regulate the Production of Adipocytes From Bone Marrow-Derived Cells. Front Endocrinol (Lausanne). 2018; 9:276. PMID: 29892267.
      View in: PubMed
    9. Gaskill CF, Carrier EJ, Kropski JA, Bloodworth NC, Menon S, Foronjy RF, Taketo MM, Hong CC, Austin ED, West JD, Means AL, Loyd JE, Merryman WD, Hemnes AR, De Langhe S, Blackwell TS, Klemm DJ, Majka SM. Disruption of lineage specification in adult pulmonary mesenchymal progenitor cells promotes microvascular dysfunction. J Clin Invest. 2017 Jun 01; 127(6):2262-2276. PMID: 28463231.
      View in: PubMed
    10. Gavin KM, Majka SM, Kohrt WM, Miller HL, Sullivan TM, Klemm DJ. Hematopoietic-to-mesenchymal transition of adipose tissue macrophages is regulated by integrin ?1 and fabricated fibrin matrices. Adipocyte. 2017 07 03; 6(3):234-249. PMID: 28441086.
      View in: PubMed
    11. Gaskill C, Marriott S, Pratap S, Menon S, Hedges LK, Fessel JP, Kropski JA, Ames D, Wheeler L, Loyd JE, Hemnes AR, Roop DR, Klemm DJ, Austin ED, Majka SM. Shared gene expression patterns in mesenchymal progenitors derived from lung and epidermis in pulmonary arterial hypertension: identifying key pathways in pulmonary vascular disease. Pulm Circ. 2016 Dec; 6(4):483-497. PMID: 28090290.
      View in: PubMed
    12. Ye H, Adane B, Khan N, Sullivan T, Minhajuddin M, Gasparetto M, Stevens B, Pei S, Balys M, Ashton JM, Klemm DJ, Woolthuis CM, Stranahan AW, Park CY, Jordan CT. Leukemic Stem Cells Evade Chemotherapy by Metabolic Adaptation to an Adipose Tissue Niche. Cell Stem Cell. 2016 07 07; 19(1):23-37. PMID: 27374788.
      View in: PubMed
    13. Keller AC, Knaub LA, McClatchey PM, Connon CA, Bouchard R, Miller MW, Geary KE, Walker LA, Klemm DJ, Reusch JE. Differential Mitochondrial Adaptation in Primary Vascular Smooth Muscle Cells from a Diabetic Rat Model. Oxid Med Cell Longev. 2016; 2016:8524267. PMID: 27034743.
      View in: PubMed
    14. Gavin KM, Gutman JA, Kohrt WM, Wei Q, Shea KL, Miller HL, Sullivan TM, Erickson PF, Helm KM, Acosta AS, Childs CR, Musselwhite E, Varella-Garcia M, Kelly K, Majka SM, Klemm DJ. De novo generation of adipocytes from circulating progenitor cells in mouse and human adipose tissue. FASEB J. 2016 Mar; 30(3):1096-108. PMID: 26581599.
      View in: PubMed
    15. Keller AC, Knaub LA, Miller MW, Birdsey N, Klemm DJ, Reusch JE. Saxagliptin restores vascular mitochondrial exercise response in the Goto-Kakizaki rat. J Cardiovasc Pharmacol. 2015 Feb; 65(2):137-47. PMID: 25264749.
      View in: PubMed
    16. Irwin DC, Garat CV, Crossno JT, MacLean PS, Sullivan TM, Erickson PF, Jackman MR, Harral JW, Reusch JE, Klemm DJ. Obesity-related pulmonary arterial hypertension in rats correlates with increased circulating inflammatory cytokines and lipids and with oxidant damage in the arterial wall but not with hypoxia. Pulm Circ. 2014 Dec; 4(4):638-53. PMID: 25610600.
      View in: PubMed
    17. Marriott S, Baskir RS, Gaskill C, Menon S, Carrier EJ, Williams J, Talati M, Helm K, Alford CE, Kropski JA, Loyd J, Wheeler L, Johnson J, Austin E, Nozik-Grayck E, Meyrick B, West JD, Klemm DJ, Majka SM. ABCG2pos lung mesenchymal stem cells are a novel pericyte subpopulation that contributes to fibrotic remodeling. Am J Physiol Cell Physiol. 2014 Oct 15; 307(8):C684-98. PMID: 25122876.
      View in: PubMed
    18. West JD, Austin ED, Gaskill C, Marriott S, Baskir R, Bilousova G, Jean JC, Hemnes AR, Menon S, Bloodworth NC, Fessel JP, Kropski JA, Irwin D, Ware LB, Wheeler L, Hong CC, Meyrick B, Loyd JE, Bowman AB, Ess KC, Klemm DJ, Young PP, Merryman WD, Kotton D, Majka SM. Identification of a common Wnt-associated genetic signature across multiple cell types in pulmonary arterial hypertension. Am J Physiol Cell Physiol. 2014 Sep 01; 307(5):C415-30. PMID: 24871858.
      View in: PubMed
    19. Geary K, Knaub LA, Schauer IE, Keller AC, Watson PA, Miller MW, Garat CV, Nadeau KJ, Cree-Green M, Pugazhenthi S, Regensteiner JG, Klemm DJ, Reusch JE. Targeting mitochondria to restore failed adaptation to exercise in diabetes. Biochem Soc Trans. 2014 Apr; 42(2):231-8. PMID: 24646223.
      View in: PubMed
    20. Majka SM, Miller HL, Helm KM, Acosta AS, Childs CR, Kong R, Klemm DJ. Analysis and isolation of adipocytes by flow cytometry. Methods Enzymol. 2014; 537:281-96. PMID: 24480352.
      View in: PubMed
    21. Garat CV, Crossno JT, Sullivan TM, Reusch JE, Klemm DJ. Inhibition of phosphatidylinositol 3-kinase/Akt signaling attenuates hypoxia-induced pulmonary artery remodeling and suppresses CREB depletion in arterial smooth muscle cells. J Cardiovasc Pharmacol. 2013 Dec; 62(6):539-48. PMID: 24084215.
      View in: PubMed
    22. McCurdy CE, Klemm DJ. Adipose tissue insulin sensitivity and macrophage recruitment: Does PI3K pick the pathway? Adipocyte. 2013 Jul 01; 2(3):135-42. PMID: 23991359.
      View in: PubMed
    23. Chow K, Fessel JP, Schmidt EP, Gaskill C, Alvarez D, Graham B, Harrison DG, Wagner DH, Nozik-Grayck E, West JD, Klemm DJ, Majka SM. Dysfunctional resident lung mesenchymal stem cells contribute to pulmonary microvascular remodeling. Pulm Circ. 2013 Jan; 3(1):31-49. PMID: 23662173.
      View in: PubMed
    24. Majka SM, Miller HL, Sullivan T, Erickson PF, Kong R, Weiser-Evans M, Nemenoff R, Moldovan R, Morandi SA, Davis JA, Klemm DJ. Adipose lineage specification of bone marrow-derived myeloid cells. Adipocyte. 2012 Oct 01; 1(4):215-229. PMID: 23700536.
      View in: PubMed
    25. McCurdy CE, Schenk S, Holliday MJ, Philp A, Houck JA, Patsouris D, MacLean PS, Majka SM, Klemm DJ, Friedman JE. Attenuated Pik3r1 expression prevents insulin resistance and adipose tissue macrophage accumulation in diet-induced obese mice. Diabetes. 2012 Oct; 61(10):2495-505. PMID: 22698915.
      View in: PubMed
    26. Klemm DJ, Majka SM, Crossno JT, Psilas JC, Reusch JE, Garat CV. Reduction of reactive oxygen species prevents hypoxia-induced CREB depletion in pulmonary artery smooth muscle cells. J Cardiovasc Pharmacol. 2011 Aug; 58(2):181-91. PMID: 21562428.
      View in: PubMed
    27. Majka SM, Barak Y, Klemm DJ. Concise review: adipocyte origins: weighing the possibilities. Stem Cells. 2011 Jul; 29(7):1034-40. PMID: 21544899.
      View in: PubMed
    28. Jun D, Garat C, West J, Thorn N, Chow K, Cleaver T, Sullivan T, Torchia EC, Childs C, Shade T, Tadjali M, Lara A, Nozik-Grayck E, Malkoski S, Sorrentino B, Meyrick B, Klemm D, Rojas M, Wagner DH, Majka SM. The pathology of bleomycin-induced fibrosis is associated with loss of resident lung mesenchymal stem cells that regulate effector T-cell proliferation. Stem Cells. 2011 Apr; 29(4):725-35. PMID: 21312316.
      View in: PubMed
    29. Bilousova G, Jun du H, King KB, De Langhe S, Chick WS, Torchia EC, Chow KS, Klemm DJ, Roop DR, Majka SM. Osteoblasts derived from induced pluripotent stem cells form calcified structures in scaffolds both in vitro and in vivo. Stem Cells. 2011 Feb; 29(2):206-16. PMID: 21732479.
      View in: PubMed
    30. Majka SM, Fox KE, Psilas JC, Helm KM, Childs CR, Acosta AS, Janssen RC, Friedman JE, Woessner BT, Shade TR, Varella-Garcia M, Klemm DJ. De novo generation of white adipocytes from the myeloid lineage via mesenchymal intermediates is age, adipose depot, and gender specific. Proc Natl Acad Sci U S A. 2010 Aug 17; 107(33):14781-6. PMID: 20679227.
      View in: PubMed
    31. Van Rheen Z, Fattman C, Domarski S, Majka S, Klemm D, Stenmark KR, Nozik-Grayck E. Lung extracellular superoxide dismutase overexpression lessens bleomycin-induced pulmonary hypertension and vascular remodeling. Am J Respir Cell Mol Biol. 2011 Apr; 44(4):500-8. PMID: 20539010.
      View in: PubMed
    32. Garat CV, Crossno JT, Sullivan TM, Reusch JE, Klemm DJ. Thiazolidinediones prevent PDGF-BB-induced CREB depletion in pulmonary artery smooth muscle cells by preventing upregulation of casein kinase 2 alpha' catalytic subunit. J Cardiovasc Pharmacol. 2010 May; 55(5):469-80. PMID: 20147842.
      View in: PubMed
    33. Schauer IE, Knaub LA, Lloyd M, Watson PA, Gliwa C, Lewis KE, Chait A, Klemm DJ, Gunter JM, Bouchard R, McDonald TO, O'Brien KD, Reusch JE. CREB downregulation in vascular disease: a common response to cardiovascular risk. Arterioscler Thromb Vasc Biol. 2010 Apr; 30(4):733-41. PMID: 20150559.
      View in: PubMed
    34. Takeda K, Okamoto M, de Langhe S, Dill E, Armstrong M, Reisdorf N, Irwin D, Koster M, Wilder J, Stenmark KR, West J, Klemm D, Gelfand EW, Nozik-Grayck E, Majka SM. Peroxisome proliferator-activated receptor-g agonist treatment increases septation and angiogenesis and decreases airway hyperresponsiveness in a model of experimental neonatal chronic lung disease. Anat Rec (Hoboken). 2009 Jul; 292(7):1045-61. PMID: 19484746.
      View in: PubMed
    35. Irwin DC, McCord JM, Nozik-Grayck E, Beckly G, Foreman B, Sullivan T, White M, T Crossno J, Bailey D, Flores SC, Majka S, Klemm D, van Patot MC. A potential role for reactive oxygen species and the HIF-1alpha-VEGF pathway in hypoxia-induced pulmonary vascular leak. Free Radic Biol Med. 2009 Jul 01; 47(1):55-61. PMID: 19358884.
      View in: PubMed
    36. Dempsey EC, Wick MJ, Karoor V, Barr EJ, Tallman DW, Wehling CA, Walchak SJ, Laudi S, Le M, Oka M, Majka S, Cool CD, Fagan KA, Klemm DJ, Hersh LB, Gerard NP, Gerard C, Miller YE. Neprilysin null mice develop exaggerated pulmonary vascular remodeling in response to chronic hypoxia. Am J Pathol. 2009 Mar; 174(3):782-96. PMID: 19234135.
      View in: PubMed
    37. Fox KE, Colton LA, Erickson PF, Friedman JE, Cha HC, Keller P, MacDougald OA, Klemm DJ. Regulation of cyclin D1 and Wnt10b gene expression by cAMP-responsive element-binding protein during early adipogenesis involves differential promoter methylation. J Biol Chem. 2008 Dec 12; 283(50):35096-105. PMID: 18957421.
      View in: PubMed
    38. Irwin D, Helm K, Campbell N, Imamura M, Fagan K, Harral J, Carr M, Young KA, Klemm D, Gebb S, Dempsey EC, West J, Majka S. Neonatal lung side population cells demonstrate endothelial potential and are altered in response to hyperoxia-induced lung simplification. Am J Physiol Lung Cell Mol Physiol. 2007 Oct; 293(4):L941-51. PMID: 17693487.
      View in: PubMed
    39. Schroeder-Gloeckler JM, Rahman SM, Janssen RC, Qiao L, Shao J, Roper M, Fischer SJ, Lowe E, Orlicky DJ, McManaman JL, Palmer C, Gitomer WL, Huang W, O'Doherty RM, Becker TC, Klemm DJ, Jensen DR, Pulawa LK, Eckel RH, Friedman JE. CCAAT/enhancer-binding protein beta deletion reduces adiposity, hepatic steatosis, and diabetes in Lepr(db/db) mice. J Biol Chem. 2007 May 25; 282(21):15717-29. PMID: 17387171.
      View in: PubMed
    40. Crossno JT, Garat CV, Reusch JE, Morris KG, Dempsey EC, McMurtry IF, Stenmark KR, Klemm DJ. Rosiglitazone attenuates hypoxia-induced pulmonary arterial remodeling. Am J Physiol Lung Cell Mol Physiol. 2007 Apr; 292(4):L885-97. PMID: 17189321.
      View in: PubMed
    41. Crossno JT, Majka SM, Grazia T, Gill RG, Klemm DJ. Rosiglitazone promotes development of a novel adipocyte population from bone marrow-derived circulating progenitor cells. J Clin Invest. 2006 Dec; 116(12):3220-8. PMID: 17143331.
      View in: PubMed
    42. Fox KE, Fankell DM, Erickson PF, Majka SM, Crossno JT, Klemm DJ. Depletion of cAMP-response element-binding protein/ATF1 inhibits adipogenic conversion of 3T3-L1 cells ectopically expressing CCAAT/enhancer-binding protein (C/EBP) alpha, C/EBP beta, or PPAR gamma 2. J Biol Chem. 2006 Dec 29; 281(52):40341-53. PMID: 17071615.
      View in: PubMed
    43. Garat CV, Fankell D, Erickson PF, Reusch JE, Bauer NN, McMurtry IF, Klemm DJ. Platelet-derived growth factor BB induces nuclear export and proteasomal degradation of CREB via phosphatidylinositol 3-kinase/Akt signaling in pulmonary artery smooth muscle cells. Mol Cell Biol. 2006 Jul; 26(13):4934-48. PMID: 16782881.
      View in: PubMed
    44. Kosmiski LA, Miller HL, Klemm DJ. In combination, nucleoside reverse transcriptase inhibitors have significant effects on 3T3-L1 adipocyte lipid accumulation and survival. Antivir Ther. 2006; 11(2):187-95. PMID: 16640100.
      View in: PubMed
    45. Crossno JT, Morris KG, Klemm DJ. Attenuation of hypoxia-induced pulmonary artery remodeling by a peroxisome proliferator-activated receptor-gamma agonist. Chest. 2005 Dec; 128(6 Suppl):580S. PMID: 16373844.
      View in: PubMed
    46. Gerasimovskaya EV, Tucker DA, Weiser-Evans M, Wenzlau JM, Klemm DJ, Banks M, Stenmark KR. Extracellular ATP-induced proliferation of adventitial fibroblasts requires phosphoinositide 3-kinase, Akt, mammalian target of rapamycin, and p70 S6 kinase signaling pathways. J Biol Chem. 2005 Jan 21; 280(3):1838-48. PMID: 15522879.
      View in: PubMed
    47. Zhang JW, Klemm DJ, Vinson C, Lane MD. Role of CREB in transcriptional regulation of CCAAT/enhancer-binding protein beta gene during adipogenesis. J Biol Chem. 2004 Feb 06; 279(6):4471-8. PMID: 14593102.
      View in: PubMed
    48. Reusch JE, Klemm DJ. Cyclic AMP response element-binding protein in the vessel wall: good or bad? Circulation. 2003 Sep 09; 108(10):1164-6. PMID: 12963681.
      View in: PubMed
    49. Reusch JE, Klemm DJ. Inhibition of cAMP-response element-binding protein activity decreases protein kinase B/Akt expression in 3T3-L1 adipocytes and induces apoptosis. J Biol Chem. 2002 Jan 11; 277(2):1426-32. PMID: 11694510.
      View in: PubMed
    50. Klemm DJ, Watson PA, Frid MG, Dempsey EC, Schaack J, Colton LA, Nesterova A, Stenmark KR, Reusch JE. cAMP response element-binding protein content is a molecular determinant of smooth muscle cell proliferation and migration. J Biol Chem. 2001 Dec 07; 276(49):46132-41. PMID: 11560924.
      View in: PubMed
    51. Watson PA, Nesterova A, Burant CF, Klemm DJ, Reusch JE. Diabetes-related changes in cAMP response element-binding protein content enhance smooth muscle cell proliferation and migration. J Biol Chem. 2001 Dec 07; 276(49):46142-50. PMID: 11560925.
      View in: PubMed
    52. Klemm DJ, Leitner JW, Watson P, Nesterova A, Reusch JE, Goalstone ML, Draznin B. Insulin-induced adipocyte differentiation. Activation of CREB rescues adipogenesis from the arrest caused by inhibition of prenylation. J Biol Chem. 2001 Jul 27; 276(30):28430-5. PMID: 11375992.
      View in: PubMed
    53. Strickland I, Kisich K, Hauk PJ, Vottero A, Chrousos GP, Klemm DJ, Leung DY. High constitutive glucocorticoid receptor beta in human neutrophils enables them to reduce their spontaneous rate of cell death in response to corticosteroids. J Exp Med. 2001 Mar 05; 193(5):585-93. PMID: 11238589.
      View in: PubMed
    54. Routes JM, Colton LA, Ryan S, Klemm DJ. CREB (cAMP response element binding protein) and C/EBPalpha (CCAAT/enhancer binding protein) are required for the superstimulation of phosphoenolpyruvate carboxykinase gene transcription by adenoviral E1a and cAMP. Biochem J. 2000 Dec 01; 352 Pt 2:335-42. PMID: 11085926.
      View in: PubMed
    55. Reusch JE, Colton LA, Klemm DJ. CREB activation induces adipogenesis in 3T3-L1 cells. Mol Cell Biol. 2000 Feb; 20(3):1008-20. PMID: 10629058.
      View in: PubMed
    56. Reusch JE, Klemm DJ. Nutrition and fat cell differentiation. Endocrinology. 1999 Jul; 140(7):2935-7. PMID: 10385383.
      View in: PubMed
    57. Klemm DJ, Roesler WJ, Boras T, Colton LA, Felder K, Reusch JE. Insulin stimulates cAMP-response element binding protein activity in HepG2 and 3T3-L1 cell lines. J Biol Chem. 1998 Jan 09; 273(2):917-23. PMID: 9422750.
      View in: PubMed
    58. Leung DY, Hamid Q, Vottero A, Szefler SJ, Surs W, Minshall E, Chrousos GP, Klemm DJ. Association of glucocorticoid insensitivity with increased expression of glucocorticoid receptor beta. J Exp Med. 1997 Nov 03; 186(9):1567-74. PMID: 9348314.
      View in: PubMed
    59. Savon SP, Hakimi P, Crawford DR, Klemm DJ, Gurney AL, Hanson RW. The promoter regulatory regions of the genes for the cytosolic form of phosphoenolpyruvate carboxykinase (GTP) from the chicken and the rat have different species-specific roles in gluconeogenesis. J Nutr. 1997 Feb; 127(2):276-85. PMID: 9039828.
      View in: PubMed
    60. Klemm DJ, Colton LA, Ryan S, Routes JM. Adenovirus E1A proteins regulate phosphoenolpyruvate carboxykinase gene transcription through multiple mechanisms. J Biol Chem. 1996 Apr 05; 271(14):8082-8. PMID: 8626493.
      View in: PubMed
    61. Routes JM, Li H, Bayley ST, Ryan S, Klemm DJ. Inhibition of IFN-stimulated gene expression and IFN induction of cytolytic resistance to natural killer cell lysis correlate with E1A-p300 binding. J Immunol. 1996 Feb 01; 156(3):1055-61. PMID: 8557979.
      View in: PubMed
    62. Rosenwasser LJ, Klemm DJ, Dresback JK, Inamura H, Mascali JJ, Klinnert M, Borish L. Promoter polymorphisms in the chromosome 5 gene cluster in asthma and atopy. Clin Exp Allergy. 1995 Nov; 25 Suppl 2:74-8; discussion 95-6. PMID: 8590350.
      View in: PubMed
    63. Roesler WJ, Graham JG, Kolen R, Klemm DJ, McFie PJ. The cAMP response element binding protein synergizes with other transcription factors to mediate cAMP responsiveness. J Biol Chem. 1995 Apr 07; 270(14):8225-32. PMID: 7713929.
      View in: PubMed
    64. Reusch JE, Hsieh P, Klemm D, Hoeffler J, Draznin B. Insulin inhibits dephosphorylation of adenosine 3',5'-monophosphate response element-binding protein/activating transcription factor-1: effect on nuclear phosphoserine phosphatase-2a. Endocrinology. 1994 Dec; 135(6):2418-22. PMID: 7988426.
      View in: PubMed
    65. Wheat WH, Roesler WJ, Klemm DJ. Simian virus 40 small tumor antigen inhibits dephosphorylation of protein kinase A-phosphorylated CREB and regulates CREB transcriptional stimulation. Mol Cell Biol. 1994 Sep; 14(9):5881-90. PMID: 8065321.
      View in: PubMed
    66. Wadzinski BE, Wheat WH, Jaspers S, Peruski LF, Lickteig RL, Johnson GL, Klemm DJ. Nuclear protein phosphatase 2A dephosphorylates protein kinase A-phosphorylated CREB and regulates CREB transcriptional stimulation. Mol Cell Biol. 1993 May; 13(5):2822-34. PMID: 8386317.
      View in: PubMed
    67. Bhandari B, Roesler WJ, DeLisio KD, Klemm DJ, Ross NS, Miller RE. A functional promoter flanks an intronless glutamine synthetase gene. J Biol Chem. 1991 Apr 25; 266(12):7784-92. PMID: 1673462.
      View in: PubMed
    68. Park EA, Roesler WJ, Liu J, Klemm DJ, Gurney AL, Thatcher JD, Shuman J, Friedman A, Hanson RW. The role of the CCAAT/enhancer-binding protein in the transcriptional regulation of the gene for phosphoenolpyruvate carboxykinase (GTP). Mol Cell Biol. 1990 Dec; 10(12):6264-72. PMID: 2147222.
      View in: PubMed
    69. Klemm DJ, Roesler WJ, Liu JS, Park EA, Hanson RW. In vitro analysis of promoter elements regulating transcription of the phosphoenolpyruvate carboxykinase (GTP) gene. Mol Cell Biol. 1990 Feb; 10(2):480-5. PMID: 2300049.
      View in: PubMed
    70. Klemm DJ, Elias L. Purification and assay of a phosphatidylglycerol-stimulated protein kinase from murine leukemic cells and its perturbation in response to IL-3 and PMA treatment. Exp Hematol. 1988 Nov; 16(10):855-60. PMID: 3262527.
      View in: PubMed
    71. Klemm DJ, Kazim AL, Elias L. Phosphatidylglycerol-modulated protein kinase activity from human spleen. I. Enzyme purification and properties. Arch Biochem Biophys. 1988 Sep; 265(2):496-505. PMID: 3421722.
      View in: PubMed
    72. Klemm DJ, Elias L. A distinctive phospholipid-stimulated protein kinase of normal and malignant murine hemopoietic cells. J Biol Chem. 1987 Jun 05; 262(16):7580-5. PMID: 3584129.
      View in: PubMed
    73. Fr?hlich G, Klemm D, Keller P. [Phytobezoar of the stomach (case report0]. Fortschr Geb Rontgenstr Nuklearmed. 1973 Feb; 118(2):226-7. PMID: 4348536.
      View in: PubMed
    Klemm's Networks
    Click the "See All" links for more information and interactive visualizations!
    Concepts Expand Description
    See all (428) concept(s)
    _
    Co-Authors Expand Description
    See all (48) people
    _
    Similar People Expand Description
    See all (60) people
    _
    Same Department Expand Description
    Search Department

    Copyright © 2024 The Regents of the University of Colorado, a body corporate. All rights reserved. (Harvard PROFILES RNS software version: 2.11.1)