Colorado PROFILES, The Colorado Clinical and Translational Sciences Institute (CCTSI)
Keywords
Last Name
Institution

Leigh Perreault

TitleClinical Associate Professor
InstitutionUniversity of Colorado Denver - Anschutz Medical Campus
DepartmentSOM-MED
Phone303/724-3947

    Collapse Research 
    Collapse research activities and funding
    R18DK127003     (PERREAULT, LEIGH)Sep 17, 2020 - Jul 31, 2025
    NIH
    PATHWEIGH: pragmatic weight management in primary care
    Role: Principal Investigator
    K23DK064811     (PERREAULT, LEIGH)Apr 1, 2004 - Mar 31, 2010
    NIH
    Intramuscular Triglyceride in Impaired Glucose Tolerance
    Role: Principal Investigator

    Collapse Bibliographic 
    Collapse selected publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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    1. Aroda VR, Perreault L. Overweight and Obesity - Capturing the Whole Picture. N Engl J Med. 2025 May 25. PMID: 40421734.
      View in: PubMed
    2. Bryan AD, Skrzynski CJ, Giordano G, Yang J, Stanger M, Bidwell LC, Hutchison KE, Perreault L. Cannabis use is associated with less peripheral inflammation but similar insulin sensitivity as non-use in healthy adults. Am J Med. 2025 May 03. PMID: 40324550.
      View in: PubMed
    3. Broussard JL, Garfield A, Zarini S, Brozinick JT, Perreault L, Newsom SA, Kahn D, Kerege A, Berry KZ, Bui HH, Bergman BC. Combined diet and exercise training decreases serum lipids associated with insulin resistance. Obesity (Silver Spring). 2024 Dec; 32(12):2334-2344. PMID: 39587896.
      View in: PubMed
    4. Jastreboff AM, le Roux CW, Stefanski A, Aronne LJ, Halpern B, Wharton S, Wilding JPH, Perreault L, Zhang S, Battula R, Bunck MC, Ahmad NN, Jouravskaya I. Tirzepatide for Obesity Treatment and Diabetes Prevention. N Engl J Med. 2025 Mar 06; 392(10):958-971. PMID: 39536238.
      View in: PubMed
    5. Zemski Berry KA, Garfield A, Jambal P, Zarini S, Perreault L, Bergman BC. Oxidised phosphatidylcholine induces sarcolemmal ceramide accumulation and insulin resistance in skeletal muscle. Diabetologia. 2024 Dec; 67(12):2819-2832. PMID: 39347985.
      View in: PubMed
    6. McKenna CF, Stierwalt HD, Zemski Berry KA, Ehrlicher SE, Robinson MM, Zarini S, Kahn DE, Snell-Bergeon JK, Perreault L, Bergman BC, Newsom SA. Intramuscular diacylglycerol accumulates with acute hyperinsulinemia in insulin-resistant phenotypes. Am J Physiol Endocrinol Metab. 2024 Aug 01; 327(2):E183-E193. PMID: 38895980.
      View in: PubMed
    7. Perreault L, Kramer ES, Smith PC, Schmidt D, Argyropoulos C. A closer look at weight loss interventions in primary care: a systematic review and meta-analysis. Front Med (Lausanne). 2023; 10:1204849. PMID: 38076252.
      View in: PubMed
    8. Perreault L, Bergman BC. Out of stock: A brief clinical reference for rough equivalency of glucagon-like peptide-1 (GLP-1) ? glucose-dependent insulinotropic polypeptide (GIP) receptor agonists for A1c and weight reduction in people with type 2 diabetes. J Diabetes. 2024 Jun; 16(6):e13505. PMID: 37986549.
      View in: PubMed
    9. Zarini S, Zemski Berry KA, Kahn DE, Garfield A, Perreault L, Kerege A, Bergman BC. Deoxysphingolipids: Atypical Skeletal Muscle Lipids Related to Insulin Resistance in Humans That Decrease Insulin Sensitivity In?Vitro. Diabetes. 2023 07 01; 72(7):884-897. PMID: 37186949.
      View in: PubMed
    10. Ritchie ND, Sauder KA, Perreault L. Glycemic Improvement and Health Equity in the National Diabetes Prevention Program. Diabetes Care. 2023 06 01; 46(6):e128-e129. PMID: 37083982.
      View in: PubMed
    11. Perreault L, Suresh K, Rodriguez C, Dickinson LM, Willems E, Smith PC, Williams J, Gritz RM, Holtrop JS. Baseline Characteristics of PATHWEIGH: A Stepped-Wedge Cluster Randomized Study for Weight Management in Primary Care. Ann Fam Med. 2023 May-Jun; 21(3):249-255. PMID: 37217322.
      View in: PubMed
    12. Zarini S, Zemski Berry KA, Kahn DE, Garfield A, Perreault L, Kerege A, Bergman BC. Deoxysphingolipids - atypical skeletal muscle lipids related to insulin resistance in humans that decrease insulin sensitivity in vitro. Diabetes. 2023 Apr 24. PMID: 37094369.
      View in: PubMed
    13. Echouffo-Tcheugui JB, Perreault L, Ji L, Dagogo-Jack S. Diagnosis and Management of Prediabetes: A Review. JAMA. 2023 04 11; 329(14):1206-1216. PMID: 37039787.
      View in: PubMed
    14. Wild J, Kaizer A, Willems E, Kramer ES, Perreault L. Prelude to PATHWEIGH: pragmatic weight management in primary care. Fam Pract. 2023 03 28; 40(2):322-329. PMID: 35997768.
      View in: PubMed
    15. Lutter D, Sachs S, Walter M, Kerege A, Perreault L, Kahn DE, Wolide AD, Kleinert M, Bergman BC, Hofmann SM. Skeletal muscle and intermuscular adipose tissue gene expression profiling identifies new biomarkers with prognostic significance for insulin resistance progression and intervention response. Diabetologia. 2023 05; 66(5):873-883. PMID: 36790478.
      View in: PubMed
    16. Summers Holtrop J, Kramer E, Gritz M, Suresh K, Perreault L, Dickinson LM, Tolle L, Williams J, Smith P. Baseline Characteristics of PATHWEIGH: A Stepped-Wedge Cluster Randomized Study for Weight Management in Primary Care. Ann Fam Med. 2023 Jan 01; 21(Suppl 1). PMID: 38226961.
      View in: PubMed
    17. Suresh K, Willems E, Williams J, Gritz RM, Dickinson LM, Perreault L, Holtrop JS. An Assessment of Weight Loss Management in Health System Primary Care Practices. J Am Board Fam Med. 2023 02 08; 36(1):51-65. PMID: 36460354.
      View in: PubMed
    18. Perreault L, Davies M, Frias JP, Laursen PN, Lingvay I, Machineni S, Varbo A, Wilding JPH, Wallenstein SOR, le Roux CW. Changes in Glucose Metabolism and Glycemic Status With Once-Weekly Subcutaneous Semaglutide 2.4 mg Among Participants With Prediabetes in the STEP Program. Diabetes Care. 2022 10 01; 45(10):2396-2405. PMID: 35724304.
      View in: PubMed
    19. Zarini S, Brozinick JT, Zemski Berry KA, Garfield A, Perreault L, Kerege A, Bui HH, Sanders P, Siddall P, Kuo MS, Bergman BC. Serum dihydroceramides correlate with insulin sensitivity in humans and decrease insulin sensitivity in?vitro. J Lipid Res. 2022 10; 63(10):100270. PMID: 36030929.
      View in: PubMed
    20. Mottl AK, Alicic R, Argyropoulos C, Brosius FC, Mauer M, Molitch M, Nelson RG, Perreault L, Nicholas SB. KDOQI US Commentary on the KDIGO 2020 Clinical Practice Guideline for Diabetes Management in CKD. Am J Kidney Dis. 2022 04; 79(4):457-479. PMID: 35144840.
      View in: PubMed
    21. Suresh K, Holtrop JS, Dickinson LM, Willems E, Smith PC, Gritz RM, Perreault L. PATHWEIGH, pragmatic weight management in adult patients in primary care in Colorado, USA: study protocol for a stepped wedge cluster randomized trial. Trials. 2022 Jan 10; 23(1):26. PMID: 35012628.
      View in: PubMed
    22. Depner CM, Melanson EL, Eckel RH, Higgins JA, Bergman BC, Perreault L, Knauer OA, Birks BR, Wright KP. Effects of ad libitum food intake, insufficient sleep and weekend recovery sleep on energy balance. Sleep. 2021 11 12; 44(11). PMID: 34059916.
      View in: PubMed
    23. Goldberg RB, Tripputi MT, Boyko EJ, Budoff M, Chen ZZ, Clark JM, Dabelea DM, Edelstein SL, Gerszten RE, Horton E, Mather KJ, Perreault L, Temprosa M, Wallia A, Watson K, Irfan Z. Hepatic Fat in Participants With and Without Incident Diabetes in the Diabetes Prevention Program Outcome Study. J Clin Endocrinol Metab. 2021 10 21; 106(11):e4746-e4765. PMID: 33705543.
      View in: PubMed
    24. Ritchie ND, Sauder KA, Kaufmann PG, Perreault L. Patient-Centered Goal-Setting in the National Diabetes Prevention Program: A Pilot Study. Diabetes Care. 2021 11; 44(11):2464-2469. PMID: 34404739.
      View in: PubMed
    25. Perreault L, Skyler JS, Rosenstock J. Novel therapies with precision mechanisms for type 2 diabetes mellitus. Nat Rev Endocrinol. 2021 06; 17(6):364-377. PMID: 33948015.
      View in: PubMed
    26. Davies M, F?rch L, Jeppesen OK, Pakseresht A, Pedersen SD, Perreault L, Rosenstock J, Shimomura I, Viljoen A, Wadden TA, Lingvay I. Semaglutide 2?4 mg once a week in adults with overweight or obesity, and type 2 diabetes (STEP 2): a randomised, double-blind, double-dummy, placebo-controlled, phase 3 trial. Lancet. 2021 03 13; 397(10278):971-984. PMID: 33667417.
      View in: PubMed
    27. Broussard JL, Perreault L, Macias E, Newsom SA, Harrison K, Bui HH, Milligan P, Roth KD, Nemkov T, D'Alessandro A, Brozinick JT, Bergman BC. Sex Differences in Insulin Sensitivity are Related to Muscle Tissue Acylcarnitine But Not Subcellular Lipid Distribution. Obesity (Silver Spring). 2021 03; 29(3):550-561. PMID: 33624435.
      View in: PubMed
    28. Aroda VR, Christophi CA, Edelstein SL, Perreault L, Kim C, Golden SH, Horton E, Mather KJ. Circulating sex hormone binding globulin levels are modified with intensive lifestyle intervention, but their changes did not independently predict diabetes risk in the Diabetes Prevention Program. BMJ Open Diabetes Res Care. 2020 12; 8(2). PMID: 33328161.
      View in: PubMed
    29. Kahn D, Perreault L, Macias E, Zarini S, Newsom SA, Strauss A, Kerege A, Harrison K, Snell-Bergeon J, Bergman BC. Subcellular localisation and composition of intramuscular triacylglycerol influence insulin sensitivity in humans. Diabetologia. 2021 01; 64(1):168-180. PMID: 33128577.
      View in: PubMed
    30. Tuttle KR, Brosius FC, Cavender MA, Fioretto P, Fowler KJ, Heerspink HJL, Manley T, McGuire DK, Molitch ME, Mottl AK, Perreault L, Rosas SE, Rossing P, Sola L, Vallon V, Wanner C, Perkovic V. SGLT2 Inhibition for CKD and Cardiovascular Disease in Type 2 Diabetes: Report of a Scientific Workshop Sponsored by the National Kidney Foundation. Diabetes. 2021 01; 70(1):1-16. PMID: 33106255.
      View in: PubMed
    31. Tuttle KR, Brosius FC, Cavender MA, Fioretto P, Fowler KJ, Heerspink HJL, Manley T, McGuire DK, Molitch ME, Mottl AK, Perreault L, Rosas SE, Rossing P, Sola L, Vallon V, Wanner C, Perkovic V. SGLT2 Inhibition for CKD and Cardiovascular Disease in Type 2 Diabetes: Report of a Scientific Workshop Sponsored by the National Kidney Foundation. Am J Kidney Dis. 2021 01; 77(1):94-109. PMID: 33121838.
      View in: PubMed
    32. Bruhn L, Vistisen D, Vain? CTR, Perreault L, F?rch K. Physiological factors contributing to HbA1c in the normal and pre-diabetic range: a cross-sectional analysis. Endocrine. 2020 05; 68(2):306-311. PMID: 32112239.
      View in: PubMed
    33. Garber AJ, Handelsman Y, Grunberger G, Einhorn D, Abrahamson MJ, Barzilay JI, Blonde L, Bush MA, DeFronzo RA, Garber JR, Garvey WT, Hirsch IB, Jellinger PS, McGill JB, Mechanick JI, Perreault L, Rosenblit PD, Samson S, Umpierrez GE. CONSENSUS STATEMENT BY THE AMERICAN ASSOCIATION OF CLINICAL ENDOCRINOLOGISTS AND AMERICAN COLLEGE OF ENDOCRINOLOGY ON THE COMPREHENSIVE TYPE 2 DIABETES MANAGEMENT ALGORITHM - 2020 EXECUTIVE SUMMARY. Endocr Pract. 2020 01; 26(1):107-139. PMID: 32022600.
      View in: PubMed
    34. Harman NL, Wilding JPH, Curry D, Harris J, Logue J, Pemberton RJ, Perreault L, Thompson G, Tunis S, Williamson PR. Selecting Core Outcomes for Randomised Effectiveness trials In Type 2 diabetes (SCORE-IT): a patient and healthcare professional consensus on a core outcome set for type 2 diabetes. BMJ Open Diabetes Res Care. 2019; 7(1):e000700. PMID: 31908789.
      View in: PubMed
    35. Coppell K, Freer T, Abel S, Whitehead L, Tipene-Leach D, Gray AR, Merriman T, Sullivan T, Krebs J, Perreault L. What predicts regression from pre-diabetes to normal glucose regulation following a primary care nurse-delivered dietary intervention? A study protocol for a prospective cohort study. BMJ Open. 2019 12 09; 9(12):e033358. PMID: 31822546.
      View in: PubMed
    36. Harding JL, Benoit SR, Gregg EW, Pavkov ME, Perreault L. Trends in Rates of Infections Requiring Hospitalization Among Adults With Versus Without Diabetes in the U.S., 2000-2015. Diabetes Care. 2020 01; 43(1):106-116. PMID: 31615853.
      View in: PubMed
    37. Chen ZZ, Liu J, Morningstar J, Heckman-Stoddard BM, Lee CG, Dagogo-Jack S, Ferguson JF, Hamman RF, Knowler WC, Mather KJ, Perreault L, Florez JC, Wang TJ, Clish C, Temprosa M, Gerszten RE. Metabolite Profiles of Incident Diabetes and Heterogeneity of Treatment Effect in the Diabetes Prevention Program. Diabetes. 2019 12; 68(12):2337-2349. PMID: 31582408.
      View in: PubMed
    38. Perreault L, Pan Q, Schroeder EB, Kalyani RR, Bray GA, Dagogo-Jack S, White NH, Goldberg RB, Kahn SE, Knowler WC, Mathioudakis N, Dabelea D. Regression From Prediabetes to Normal Glucose Regulation and Prevalence of Microvascular Disease in the Diabetes Prevention Program Outcomes Study (DPPOS). Diabetes Care. 2019 09; 42(9):1809-1815. PMID: 31320445.
      View in: PubMed
    39. Vistisen D, Kivim?ki M, Perreault L, Hulman A, Witte DR, Brunner EJ, Tab?k A, J?rgensen ME, F?rch K. Reversion from prediabetes to normoglycaemia and risk of cardiovascular disease and mortality: the Whitehall II cohort study. Diabetologia. 2019 08; 62(8):1385-1390. PMID: 31123789.
      View in: PubMed
    40. Perreault L, Vincent L, Neumiller JJ, Santos-Cavaiola T. Initiation and Titration of Basal Insulin in Primary Care: Barriers and Practical Solutions. J Am Board Fam Med. 2019 May-Jun; 32(3):431-447. PMID: 31068410.
      View in: PubMed
    41. Herman WH, Pan Q, Edelstein SL, Mather KJ, Perreault L, Barrett-Connor E, Dabelea DM, Horton E, Kahn SE, Knowler WC, Lorenzo C, Pi-Sunyer X, Venditti E, Ye W. Erratum. Impact of lifestyle and metformin interventions on the risk of progression to diabetes and regression to normal glucose regulation in overweight or obese people with impaired glucose regulation. Diabetes Care 2017;40:1668-1677. Diabetes Care. 2019 Apr; 42(4):701. PMID: 30894384.
      View in: PubMed
    42. Depner CM, Melanson EL, Eckel RH, Snell-Bergeon JK, Perreault L, Bergman BC, Higgins JA, Guerin MK, Stothard ER, Morton SJ, Wright KP. Ad libitum Weekend Recovery Sleep Fails to Prevent Metabolic Dysregulation during a Repeating Pattern of Insufficient Sleep and Weekend Recovery Sleep. Curr Biol. 2019 03 18; 29(6):957-967.e4. PMID: 30827911.
      View in: PubMed
    43. Perreault L, Boardman MK, Pak J. The Association Between Type 2 Diabetes and Cardiovascular Disease: The "For Your SweetHeart?" Survey. Adv Ther. 2019 03; 36(3):746-755. PMID: 30758740.
      View in: PubMed
    44. Sachs S, Zarini S, Kahn DE, Harrison KA, Perreault L, Phang T, Newsom SA, Strauss A, Kerege A, Schoen JA, Bessesen DH, Schwarzmayr T, Graf E, Lutter D, Krumsiek J, Hofmann SM, Bergman BC. Intermuscular adipose tissue directly modulates skeletal muscle insulin sensitivity in humans. Am J Physiol Endocrinol Metab. 2019 05 01; 316(5):E866-E879. PMID: 30620635.
      View in: PubMed
    45. Perreault L, Rodbard H, Valentine V, Johnson E. Optimizing Fixed-Ratio Combination Therapy in Type 2 Diabetes. Adv Ther. 2019 02; 36(2):265-277. PMID: 30610613.
      View in: PubMed
    46. Goldberg RB, Bray GA, Marcovina SM, Mather KJ, Orchard TJ, Perreault L, Temprosa M. Non-traditional biomarkers and incident diabetes in the Diabetes Prevention Program: comparative effects of lifestyle and metformin interventions. Diabetologia. 2019 01; 62(1):58-69. PMID: 30334082.
      View in: PubMed
    47. Perreault L. GOALS FOR MEDICAL TREATMENT IN OBESITY AND PREDIABETES: IMPROVING OUTCOMES FOR BOTH. Endocr Pract. 2018 Dec; 24(12):1093-1098. PMID: 30289308.
      View in: PubMed
    48. Harman NL, Wilding J, Curry D, Harris J, Logue J, Pemberton RJ, Perreault L, Thompson G, Tunis S, Williamson PR. Selecting Core Outcomes for Randomised Effectiveness trials In Type 2 Diabetes (SCORE-IT): study protocol for the development of a core outcome set. Trials. 2018 Aug 07; 19(1):427. PMID: 30086771.
      View in: PubMed
    49. Su W, Chen F, Dall TM, Zvenyach T, Kyle TK, Perreault L. Where can obesity management policy make the largest impact? Evaluating sub-populations through a microsimulation approach. J Med Econ. 2018 Sep; 21(9):936-943. PMID: 29973101.
      View in: PubMed
    50. Herman WH, Pan Q, Edelstein SL, Mather KJ, Perreault L, Barrett-Connor E, Dabelea DM, Horton E, Kahn SE, Knowler WC, Lorenzo C, Pi-Sunyer X, Venditti E, Ye W. Erratum. Impact of Lifestyle and Metformin Interventions on the Risk of Progression to Diabetes and Regression to Normal Glucose Regulation in Overweight or Obese People With Impaired Glucose Regulation. Diabetes Care 2017;40:1668-1677. Diabetes Care. 2018 04; 41(4):913. PMID: 29475844.
      View in: PubMed
    51. Perreault L, Newsom SA, Strauss A, Kerege A, Kahn DE, Harrison KA, Snell-Bergeon JK, Nemkov T, D'Alessandro A, Jackman MR, MacLean PS, Bergman BC. Intracellular localization of diacylglycerols and sphingolipids influences insulin sensitivity and mitochondrial function in human skeletal muscle. JCI Insight. 2018 02 08; 3(3). PMID: 29415895.
      View in: PubMed
    52. Herman WH, Pan Q, Edelstein SL, Mather KJ, Perreault L, Barrett-Connor E, Dabelea DM, Horton E, Kahn SE, Knowler WC, Lorenzo C, Pi-Sunyer X, Venditti E, Ye W. Impact of Lifestyle and Metformin Interventions on the Risk of Progression to Diabetes and Regression to Normal Glucose Regulation in Overweight or Obese People With Impaired Glucose Regulation. Diabetes Care. 2017 12; 40(12):1668-1677. PMID: 29021207.
      View in: PubMed
    53. Bergman BC, Perreault L, Strauss A, Bacon S, Kerege A, Harrison K, Brozinick JT, Hunerdosse DM, Playdon MC, Holmes W, Bui HH, Sanders P, Siddall P, Wei T, Thomas MK, Kuo MS, Eckel RH. Intramuscular triglyceride synthesis: importance in muscle lipid partitioning in humans. Am J Physiol Endocrinol Metab. 2018 02 01; 314(2):E152-E164. PMID: 28978544.
      View in: PubMed
    54. Perreault L, Pan Q, Aroda VR, Barrett-Connor E, Dabelea D, Dagogo-Jack S, Hamman RF, Kahn SE, Mather KJ, Knowler WC. Exploring residual risk for diabetes and microvascular disease in the Diabetes Prevention Program Outcomes Study (DPPOS). Diabet Med. 2017 12; 34(12):1747-1755. PMID: 28833481.
      View in: PubMed
    55. Perreault L, F?rch K, Gregg EW. Can Cardiovascular Epidemiology and Clinical Trials Close the Risk Management Gap Between Diabetes and Prediabetes? Curr Diab Rep. 2017 Sep; 17(9):77. PMID: 28766246.
      View in: PubMed
    56. Aroda VR, Knowler WC, Crandall JP, Perreault L, Edelstein SL, Jeffries SL, Molitch ME, Pi-Sunyer X, Darwin C, Heckman-Stoddard BM, Temprosa M, Kahn SE, Nathan DM. Metformin for diabetes prevention: insights gained from the Diabetes Prevention Program/Diabetes Prevention Program Outcomes Study. Diabetologia. 2017 09; 60(9):1601-1611. PMID: 28770322.
      View in: PubMed
    57. Perreault L. EMPA-REG OUTCOME: The Endocrinologist's Point of View. Am J Med. 2017 Jun; 130(6S):S51-S56. PMID: 28526185.
      View in: PubMed
    58. Perreault L. EMPA-REG OUTCOME: The Endocrinologist's Point of View. Am J Cardiol. 2017 07 01; 120(1S):S48-S52. PMID: 28606344.
      View in: PubMed
    59. Goldberg RB, Temprosa M, Mele L, Orchard T, Mather K, Bray G, Horton E, Kitabchi A, Krakoff J, Marcovina S, Perreault L, White N. Erratum to: "Change in adiponectin explains most of the change in HDL particles induced by lifestyle intervention but not metformin treatment in the diabetes prevention program" [Metabolism (2016) 65; 764-775]. Metabolism. 2017 03; 68:184-186. PMID: 28065437.
      View in: PubMed
    60. Newsom SA, Brozinick JT, Kiseljak-Vassiliades K, Strauss AN, Bacon SD, Kerege AA, Bui HH, Sanders P, Siddall P, Wei T, Thomas M, Kuo MS, Nemkov T, D'Alessandro A, Hansen KC, Perreault L, Bergman BC. Skeletal muscle phosphatidylcholine and phosphatidylethanolamine are related to insulin sensitivity and respond to acute exercise in humans. J Appl Physiol (1985). 2016 Jun 01; 120(11):1355-63. PMID: 27032901.
      View in: PubMed
    61. Guess N, Perreault L, Kerege A, Strauss A, Bergman BC. Dietary Fatty Acids Differentially Associate with Fasting Versus 2-Hour Glucose Homeostasis: Implications for The Management of Subtypes of Prediabetes. PLoS One. 2016; 11(3):e0150148. PMID: 26999667.
      View in: PubMed
    62. Su W, Chen F, Dall TM, Iacobucci W, Perreault L. Return on Investment for Digital Behavioral Counseling in Patients With Prediabetes and Cardiovascular Disease. Prev Chronic Dis. 2016 Jan 28; 13:E13. PMID: 26820045.
      View in: PubMed
    63. Bergman BC, Brozinick JT, Strauss A, Bacon S, Kerege A, Bui HH, Sanders P, Siddall P, Wei T, Thomas MK, Kuo MS, Perreault L. Muscle sphingolipids during rest and exercise: a C18:0 signature for insulin resistance in humans. Diabetologia. 2016 Apr; 59(4):785-98. PMID: 26739815.
      View in: PubMed
    64. Goldberg RB, Temprosa M, Mele L, Orchard T, Mather K, Bray G, Horton E, Kitabchi A, Krakoff J, Marcovina S, Perreault L, White N. Change in adiponectin explains most of the change in HDL particles induced by lifestyle intervention but not metformin treatment in the Diabetes Prevention Program. Metabolism. 2016 May; 65(5):764-775. PMID: 27085783.
      View in: PubMed
    65. Perreault L, Starling AP, Glueck D, Brozinick JT, Sanders P, Siddall P, Kuo MS, Dabelea D, Bergman BC. Biomarkers of Ectopic Fat Deposition: The Next Frontier in Serum Lipidomics. J Clin Endocrinol Metab. 2016 Jan; 101(1):176-82. PMID: 26574956.
      View in: PubMed
    66. Eckel RH, Depner CM, Perreault L, Markwald RR, Smith MR, McHill AW, Higgins J, Melanson EL, Wright KP. Morning Circadian Misalignment during Short Sleep Duration Impacts Insulin Sensitivity. Curr Biol. 2015 Nov 16; 25(22):3004-10. PMID: 26549253.
      View in: PubMed
    67. Hivert MF, Christophi CA, Franks PW, Jablonski KA, Ehrmann DA, Kahn SE, Horton ES, Pollin TI, Mather KJ, Perreault L, Barrett-Connor E, Knowler WC, Florez JC. Lifestyle and Metformin Ameliorate Insulin Sensitivity Independently of the Genetic Burden of Established Insulin Resistance Variants in Diabetes Prevention Program Participants. Diabetes. 2016 Feb; 65(2):520-6. PMID: 26525880.
      View in: PubMed
    68. Su W, Huang J, Chen F, Iacobucci W, Mocarski M, Dall TM, Perreault L. Modeling the clinical and economic implications of obesity using microsimulation. J Med Econ. 2015; 18(11):886-97. PMID: 26057567.
      View in: PubMed
    69. Bergman BC, Brozinick JT, Strauss A, Bacon S, Kerege A, Bui HH, Sanders P, Siddall P, Kuo MS, Perreault L. Serum sphingolipids: relationships to insulin sensitivity and changes with exercise in humans. Am J Physiol Endocrinol Metab. 2015 Aug 15; 309(4):E398-408. PMID: 26126684.
      View in: PubMed
    70. Kim C, Christophi CA, Goldberg RB, Perreault L, Dabelea D, Marcovina SM, Pi-Sunyer X, Barrett-Connor E. Adiponectin, C-reactive protein, fibrinogen and tissue plasminogen activator antigen levels among glucose-intolerant women with and without histories of gestational diabetes. Diabet Med. 2016 Jan; 33(1):32-8. PMID: 25970741.
      View in: PubMed
    71. Delahanty LM, Pan Q, Jablonski KA, Aroda VR, Watson KE, Bray GA, Kahn SE, Florez JC, Perreault L, Franks PW. Effects of weight loss, weight cycling, and weight loss maintenance on diabetes incidence and change in cardiometabolic traits in the Diabetes Prevention Program. Diabetes Care. 2014 Oct; 37(10):2738-45. PMID: 25024396.
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    72. Perreault L, Temprosa M, Mather KJ, Horton E, Kitabchi A, Larkin M, Montez MG, Thayer D, Orchard TJ, Hamman RF, Goldberg RB. Regression from prediabetes to normal glucose regulation is associated with reduction in cardiovascular risk: results from the Diabetes Prevention Program outcomes study. Diabetes Care. 2014 Sep; 37(9):2622-31. PMID: 24969574.
      View in: PubMed
    73. Perreault L, F?rch K, Kerege AA, Bacon SD, Bergman BC. Hepatic glucose sensing is impaired, but can be normalized, in people with impaired fasting glucose. J Clin Endocrinol Metab. 2014 Jul; 99(7):E1154-62. PMID: 24731008.
      View in: PubMed
    74. Perreault L, F?rch K. Approaching pre-diabetes. J Diabetes Complications. 2014 Mar-Apr; 28(2):226-33. PMID: 24342268.
      View in: PubMed
    75. Perreault L, McCurdy C, Kerege AA, Houck J, F?rch K, Bergman BC. Bisphenol A impairs hepatic glucose sensing in C57BL/6 male mice. PLoS One. 2013; 8(7):e69991. PMID: 23922885.
      View in: PubMed
    76. Markwald RR, Melanson EL, Smith MR, Higgins J, Perreault L, Eckel RH, Wright KP. Impact of insufficient sleep on total daily energy expenditure, food intake, and weight gain. Proc Natl Acad Sci U S A. 2013 Apr 02; 110(14):5695-700. PMID: 23479616.
      View in: PubMed
    77. F?rch K, Witte DR, Tab?k AG, Perreault L, Herder C, Brunner EJ, Kivim?ki M, Vistisen D. Trajectories of cardiometabolic risk factors before diagnosis of three subtypes of type 2 diabetes: a post-hoc analysis of the longitudinal Whitehall II cohort study. Lancet Diabetes Endocrinol. 2013 Sep; 1(1):43-51. PMID: 24622266.
      View in: PubMed
    78. Bergman BC, Howard D, Schauer IE, Maahs DM, Snell-Bergeon JK, Clement TW, Eckel RH, Perreault L, Rewers M. The importance of palmitoleic acid to adipocyte insulin resistance and whole-body insulin sensitivity in type 1 diabetes. J Clin Endocrinol Metab. 2013 Jan; 98(1):E40-50. PMID: 23150678.
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    79. Price DW, Ma Y, Rubin RR, Perreault L, Bray GA, Marrero D, Knowler WC, Barrett-Connor E, Lacoursiere DY. Depression as a predictor of weight regain among successful weight losers in the diabetes prevention program. Diabetes Care. 2013 Feb; 36(2):216-21. PMID: 23002085.
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    80. Bergman BC, Perreault L, Hunerdosse D, Kerege A, Playdon M, Samek AM, Eckel RH. Novel and reversible mechanisms of smoking-induced insulin resistance in humans. Diabetes. 2012 Dec; 61(12):3156-66. PMID: 22966072.
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    81. F?rch K, Bergman B, Perreault L. Does insulin resistance drive the association between hyperglycemia and cardiovascular risk? PLoS One. 2012; 7(6):e39260. PMID: 22720085.
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    82. Perreault L, Pan Q, Mather KJ, Watson KE, Hamman RF, Kahn SE. Effect of regression from prediabetes to normal glucose regulation on long-term reduction in diabetes risk: results from the Diabetes Prevention Program Outcomes Study. Lancet. 2012 Jun 16; 379(9833):2243-51. PMID: 22683134.
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    83. Bergman BC, Howard D, Schauer IE, Maahs DM, Snell-Bergeon JK, Eckel RH, Perreault L, Rewers M. Features of hepatic and skeletal muscle insulin resistance unique to type 1 diabetes. J Clin Endocrinol Metab. 2012 May; 97(5):1663-72. PMID: 22362823.
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    84. Bergman BC, Hunerdosse DM, Kerege A, Playdon MC, Perreault L. Localisation and composition of skeletal muscle diacylglycerol predicts insulin resistance in humans. Diabetologia. 2012 Apr; 55(4):1140-50. PMID: 22252470.
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    85. Florez H, Ma Y, Crandall JP, Perreault L, Marcovina SM, Bray GA, Saudek CD, Barrett-Connor E, Knowler WC. Parental longevity and diabetes risk in the Diabetes Prevention Program. J Gerontol A Biol Sci Med Sci. 2011 Nov; 66(11):1211-7. PMID: 21852284.
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    86. Kim C, Edelstein SL, Crandall JP, Dabelea D, Kitabchi AE, Hamman RF, Montez MG, Perreault L, Foulkes MA, Barrett-Connor E. Menopause and risk of diabetes in the Diabetes Prevention Program. Menopause. 2011 Aug; 18(8):857-68. PMID: 21709591.
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    87. Hivert MF, Jablonski KA, Perreault L, Saxena R, McAteer JB, Franks PW, Hamman RF, Kahn SE, Haffner S, Meigs JB, Altshuler D, Knowler WC, Florez JC. Updated genetic score based on 34 confirmed type 2 diabetes Loci is associated with diabetes incidence and regression to normoglycemia in the diabetes prevention program. Diabetes. 2011 Apr; 60(4):1340-8. PMID: 21378175.
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    88. Perreault L, Bergman BC, Hunerdosse DM, Howard DJ, Eckel RH. Fenofibrate administration does not affect muscle triglyceride concentration or insulin sensitivity in humans. Metabolism. 2011 Aug; 60(8):1107-14. PMID: 21306746.
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    89. Jung CM, Melanson EL, Frydendall EJ, Perreault L, Eckel RH, Wright KP. Energy expenditure during sleep, sleep deprivation and sleep following sleep deprivation in adult humans. J Physiol. 2011 Jan 01; 589(Pt 1):235-44. PMID: 21059762.
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    90. Perreault L, Man CD, Hunerdosse DM, Cobelli C, Bergman BC. Incretin action maintains insulin secretion, but not hepatic insulin action, in people with impaired fasting glucose. Diabetes Res Clin Pract. 2010 Oct; 90(1):87-94. PMID: 20708814.
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    91. Perreault L, Bergman BC, Hunerdosse DM, Eckel RH. Altered intramuscular lipid metabolism relates to diminished insulin action in men, but not women, in progression to diabetes. Obesity (Silver Spring). 2010 Nov; 18(11):2093-100. PMID: 20379150.
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    92. Bergman BC, Perreault L, Hunerdosse DM, Koehler MC, Samek AM, Eckel RH. Increased intramuscular lipid synthesis and low saturation relate to insulin sensitivity in endurance-trained athletes. J Appl Physiol (1985). 2010 May; 108(5):1134-41. PMID: 20299618.
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    93. Perreault L, Bergman BC, Hunerdosse DM, Playdon MC, Eckel RH. Inflexibility in intramuscular triglyceride fractional synthesis distinguishes prediabetes from obesity in humans. Obesity (Silver Spring). 2010 Aug; 18(8):1524-31. PMID: 20035285.
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    94. Crandall JP, Polsky S, Howard AA, Perreault L, Bray GA, Barrett-Connor E, Brown-Friday J, Whittington T, Foo S, Ma Y, Edelstein SL. Alcohol consumption and diabetes risk in the Diabetes Prevention Program. Am J Clin Nutr. 2009 Sep; 90(3):595-601. PMID: 19640960.
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    95. Perreault L, Kahn SE, Christophi CA, Knowler WC, Hamman RF. Regression from pre-diabetes to normal glucose regulation in the diabetes prevention program. Diabetes Care. 2009 Sep; 32(9):1583-8. PMID: 19587364.
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    96. Bergman BC, Perreault L, Hunerdosse DM, Koehler MC, Samek AM, Eckel RH. Intramuscular lipid metabolism in the insulin resistance of smoking. Diabetes. 2009 Oct; 58(10):2220-7. PMID: 19581421.
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    97. Perreault L, Bergman BC, Playdon MC, Dalla Man C, Cobelli C, Eckel RH. Impaired fasting glucose with or without impaired glucose tolerance: progressive or parallel states of prediabetes? Am J Physiol Endocrinol Metab. 2008 Aug; 295(2):E428-35. PMID: 18523123.
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    98. Perreault L, Ma Y, Dagogo-Jack S, Horton E, Marrero D, Crandall J, Barrett-Connor E. Sex differences in diabetes risk and the effect of intensive lifestyle modification in the Diabetes Prevention Program. Diabetes Care. 2008 Jul; 31(7):1416-21. PMID: 18356403.
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    99. Perreault L, Lavely JM, Bergman BC, Horton TJ. Gender differences in insulin action after a single bout of exercise. J Appl Physiol (1985). 2004 Sep; 97(3):1013-21. PMID: 15145925.
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    100. Perreault L, Lavely JM, Kittelson JM, Horton TJ. Gender differences in lipoprotein lipase activity after acute exercise. Obes Res. 2004 Feb; 12(2):241-9. PMID: 14981216.
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    101. Dean TM, Perreault L, Mazzeo RS, Horton TJ. No effect of menstrual cycle phase on lactate threshold. J Appl Physiol (1985). 2003 Dec; 95(6):2537-43. PMID: 14600163.
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    102. Warriner CB, Knox D, Belo S, Cole C, Finegan BA, Perreault L. Prophylactic oral dolasetron mesylate reduces nausea and vomiting after abdominal hysterectomy. The Canadian Dolasetron Study Group. Can J Anaesth. 1997 Nov; 44(11):1167-73. PMID: 9398956.
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    103. Fuchs VR, Perreault L. Expenditures for reproduction-related health care. JAMA. 1986 Jan 03; 255(1):76-81. PMID: 3079616.
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