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Judith Tamara Blaine

TitleAssociate Professor
InstitutionUniversity of Colorado Denver - Anschutz Medical Campus
DepartmentSOM-MED
Phone303/724-4841

    Collapse Research 
    Collapse research activities and funding
    F30MH011349     (BLAINE, JUDITH T)Oct 17, 1996
    NIH/NIMH
    MOLECULAR IDENTIFICATION OF FUNCTIONAL K+ CHANNELS
    Role: Principal Investigator
    F32DK076441     (BLAINE, JUDITH T)Jul 1, 2006 - Jun 30, 2007
    NIH/NIDDK
    Trafficking of NaPilla in brush border microvilli
    Role: Principal Investigator
    K08DK080989     (BLAINE, JUDITH T)Sep 1, 2009 - Aug 31, 2014
    NIH/NIDDK
    Molecular Mechanisms of PTH-Mediated Trafficking in Renal Tubular Cells
    Role: Principal Investigator
    R03DK099544     (BLAINE, JUDITH T)Jul 1, 2013 - Jun 30, 2015
    NIH/NIDDK
    Molecular Mechanisms of Albumin Trafficking in Podocytes
    Role: Principal Investigator
    R01DK104264     (BLAINE, JUDITH T)Sep 1, 2015 - Jul 31, 2020
    NIH/NIDDK
    The Dual Role of the Neonatal Fc Receptor (FcRn) in Podocytes
    Role: Principal Investigator

    Collapse Bibliographic 
    Collapse selected publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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    1. Dylewski J, Dobrinskikh E, Lewis L, Tonsawan P, Miyazaki M, Jat PS, Blaine J. Differential trafficking of albumin and IgG facilitated by the neonatal Fc receptor in podocytes in vitro and in vivo. PLoS One. 2019; 14(2):e0209732. PMID: 30811433.
      View in: PubMed
    2. Dobrinskikh E, Lewis L, Brian Doctor R, Okamura K, Lee MG, Altmann C, Faubel S, Kopp JB, Blaine J. Shank2 Regulates Renal Albumin Endocytosis. Physiol Rep. 2015 Sep; 3(9). PMID: 26333830; PMCID: PMC4600376.
      View in: PubMed, PubMed Central
    3. Blaine J, Chonchol M, Levi M. Renal control of calcium, phosphate, and magnesium homeostasis. Clin J Am Soc Nephrol. 2015 Jul 07; 10(7):1257-72. PMID: 25287933; PMCID: PMC4491294.
      View in: PubMed, PubMed Central
    4. Hung KW, Blaine J, Faubel S. Dual therapy difficulties in angiotensin blockade for proteinuria: a teachable moment. JAMA Intern Med. 2014 Sep; 174(9):1429-30. PMID: 25089763.
      View in: PubMed
    5. Carson JM, Okamura K, Wakashin H, McFann K, Dobrinskikh E, Kopp JB, Blaine J. Podocytes degrade endocytosed albumin primarily in lysosomes. PLoS One. 2014; 9(6):e99771. PMID: 24924335; PMCID: PMC4055698.
      View in: PubMed, PubMed Central
    6. Dobrinskikh E, Okamura K, Kopp JB, Doctor RB, Blaine J. Human podocytes perform polarized, caveolae-dependent albumin endocytosis. Am J Physiol Renal Physiol. 2014 May 01; 306(9):F941-51. PMID: 24573386; PMCID: PMC4010685.
      View in: PubMed, PubMed Central
    7. Okamura K, Dummer P, Kopp J, Qiu L, Levi M, Faubel S, Blaine J. Endocytosis of albumin by podocytes elicits an inflammatory response and induces apoptotic cell death. PLoS One. 2013; 8(1):e54817. PMID: 23382978; PMCID: PMC3557279.
      View in: PubMed, PubMed Central
    8. Blaine J, Levi M. Chronic kidney disease: Albuminuria or CKD stage as best marker of CVD in diabetes? Nat Rev Nephrol. 2012 May 29; 8(7):376-7. PMID: 22641078.
      View in: PubMed
    9. Caldas YA, Giral H, Cortázar MA, Sutherland E, Okamura K, Blaine J, Sorribas V, Koepsell H, Levi M. Liver X receptor-activating ligands modulate renal and intestinal sodium-phosphate transporters. Kidney Int. 2011 Sep; 80(5):535-44. PMID: 21677638; PMCID: PMC3428205.
      View in: PubMed, PubMed Central
    10. Lanzano L, Lei T, Okamura K, Giral H, Caldas Y, Masihzadeh O, Gratton E, Levi M, Blaine J. Differential modulation of the molecular dynamics of the type IIa and IIc sodium phosphate cotransporters by parathyroid hormone. Am J Physiol Cell Physiol. 2011 Oct; 301(4):C850-61. PMID: 21593452; PMCID: PMC3191571.
      View in: PubMed, PubMed Central
    11. Giral H, Lanzano L, Caldas Y, Blaine J, Verlander JW, Lei T, Gratton E, Levi M. Role of PDZK1 protein in apical membrane expression of renal sodium-coupled phosphate transporters. J Biol Chem. 2011 Apr 29; 286(17):15032-42. PMID: 21388960; PMCID: PMC3083164.
      View in: PubMed, PubMed Central
    12. Blaine J, Weinman EJ, Cunningham R. The regulation of renal phosphate transport. Adv Chronic Kidney Dis. 2011 Mar; 18(2):77-84. PMID: 21406291.
      View in: PubMed
    13. Blaine J, Lanzano L, Giral H, Caldas Y, Levi M, Gratton E, Moldovan R, Lei T. Dynamic imaging of the sodium phosphate cotransporters. Adv Chronic Kidney Dis. 2011 Mar; 18(2):145-50. PMID: 21406299; PMCID: PMC3220941.
      View in: PubMed, PubMed Central
    14. Blaine J, Okamura K, Giral H, Breusegem S, Caldas Y, Millard A, Barry N, Levi M. PTH-induced internalization of apical membrane NaPi2a: role of actin and myosin VI. Am J Physiol Cell Physiol. 2009 Dec; 297(6):C1339-46. PMID: 19776390; PMCID: PMC2793059.
      View in: PubMed, PubMed Central
    15. Giral H, Caldas Y, Sutherland E, Wilson P, Breusegem S, Barry N, Blaine J, Jiang T, Wang XX, Levi M. Regulation of rat intestinal Na-dependent phosphate transporters by dietary phosphate. Am J Physiol Renal Physiol. 2009 Nov; 297(5):F1466-75. PMID: 19675183; PMCID: PMC2781338.
      View in: PubMed, PubMed Central
    16. Breusegem SY, Takahashi H, Giral-Arnal H, Wang X, Jiang T, Verlander JW, Wilson P, Miyazaki-Anzai S, Sutherland E, Caldas Y, Blaine JT, Segawa H, Miyamoto K, Barry NP, Levi M. Differential regulation of the renal sodium-phosphate cotransporters NaPi-IIa, NaPi-IIc, and PiT-2 in dietary potassium deficiency. Am J Physiol Renal Physiol. 2009 Aug; 297(2):F350-61. PMID: 19493963; PMCID: PMC2724260.
      View in: PubMed, PubMed Central
    17. Levi M, Blaine J, Breusegem S, Takahashi H, Sorribas V, Barry N. Renal phosphate-wasting disorders. Adv Chronic Kidney Dis. 2006 Apr; 13(2):155-65. PMID: 16580617.
      View in: PubMed
    18. Perry C, Blaine J, Le H, Grichtchenko II. PMA- and ANG II-induced PKC regulation of the renal Na+-HCO3- cotransporter (hkNBCe1). Am J Physiol Renal Physiol. 2006 Feb; 290(2):F417-27. PMID: 16159892.
      View in: PubMed
    19. Blaine JT, Taylor AD, Ribera AB. Carboxyl tail region of the Kv2.2 subunit mediates novel developmental regulation of channel density. J Neurophysiol. 2004 Dec; 92(6):3446-54. PMID: 15306626.
      View in: PubMed
    20. Blaine JT, Ribera AB. Kv2 channels form delayed-rectifier potassium channels in situ. J Neurosci. 2001 Mar 01; 21(5):1473-80. PMID: 11222637.
      View in: PubMed
    21. Blaine JT, Ribera AB. Heteromultimeric potassium channels formed by members of the Kv2 subfamily. J Neurosci. 1998 Dec 01; 18(23):9585-93. PMID: 9822719.
      View in: PubMed
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