 Judith Tamara Blaine
| Title | Professor |
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| Institution | University of Colorado Denver - Anschutz Medical Campus |
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| Department | SOM-MED |
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| Phone | 303/724-4841 |
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 Research F30MH011349 (BLAINE, JUDITH T)Oct 17, 1996 NIH/NIMH
MOLECULAR IDENTIFICATION OF FUNCTIONAL K+ CHANNELS
Role: Principal Investigator |
| F32DK076441 (BLAINE, JUDITH T)Jul 1, 2006 - Jun 30, 2007 NIH/NIDDK
Trafficking of NaPilla in brush border microvilli
Role: Principal Investigator |
| K08DK080989 (BLAINE, JUDITH T)Sep 1, 2009 - Aug 31, 2014 NIH/NIDDK
Molecular Mechanisms of PTH-Mediated Trafficking in Renal Tubular Cells
Role: Principal Investigator |
| R03DK099544 (BLAINE, JUDITH T)Jul 1, 2013 - Jun 30, 2015 NIH/NIDDK
Molecular Mechanisms of Albumin Trafficking in Podocytes
Role: Principal Investigator |
| R01DK104264 (BLAINE, JUDITH T.)Sep 1, 2015 - Jul 31, 2020 NIH/NIDDK
The Dual Role of the Neonatal Fc Receptor (FcRn) in Podocytes
Role: Principal Investigator |
Bibliographic
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Brown CN, Atwood D, Pokhrel D, Holditch SJ, Altmann C, Skrypnyk NI, Bourne J, Klawitter J, Blaine J, Faubel S, Thorburn A, Edelstein CL. Surgical procedures suppress autophagic flux in the kidney. Cell Death Dis. 2021 03 05; 12(3):248. PMID: 33674554.
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Blaine J. Generating a Podocyte-Specific Neonatal F Receptor (FcRn) Knockout Mouse. Methods Mol Biol. 2021; 2224:123-132. PMID: 33606211.
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Dylewski JF, Tonsawan P, Garcia G, Lewis L, Blaine J. Podocyte-specific knockout of the neonatal Fc receptor (FcRn) results in differential protection depending on the model of glomerulonephritis. PLoS One. 2020; 15(12):e0230401. PMID: 33370294.
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Dylewski JF, Wilson N, Lu S, Jat P, Weiser-Evans M, Panzer SE, Blaine J. Isolation, purification, and conditional immortalization of murine glomerular endothelial cells of microvascular phenotype. MethodsX. 2020; 7:101048. PMID: 32944514.
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Blaine J, Dylewski J. Regulation of the Actin Cytoskeleton in Podocytes. Cells. 2020 07 16; 9(7). PMID: 32708597.
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Wilson NA, Dylewski J, Degner KR, O'Neill MA, Reese SR, Hidalgo LG, Blaine J, Panzer SE. An in vitro model of antibody-mediated injury to glomerular endothelial cells: Upregulation of MHC class II and adhesion molecules. Transpl Immunol. 2020 02; 58:101261. PMID: 31887408.
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Skrypnyk NI, Gist KM, Okamura K, Montford JR, You Z, Yang H, Moldovan R, Bodoni E, Blaine JT, Edelstein CL, Soranno DE, Kirkbride-Romeo LA, Griffin BR, Altmann C, Faubel S. IL-6-mediated hepatocyte production is the primary source of plasma and urine neutrophil gelatinase-associated lipocalin during acute kidney injury. Kidney Int. 2020 05; 97(5):966-979. PMID: 32081304.
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Tonsawan P, Dylewski J, Lewis L, Blaine J. Knockout of the neonatal Fc receptor in cultured podocytes alters IL-6 signaling and the actin cytoskeleton. Am J Physiol Cell Physiol. 2019 11 01; 317(5):C1048-C1060. PMID: 31553647.
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Dylewski J, Dobrinskikh E, Lewis L, Tonsawan P, Miyazaki M, Jat PS, Blaine J. Differential trafficking of albumin and IgG facilitated by the neonatal Fc receptor in podocytes in vitro and in vivo. PLoS One. 2019; 14(2):e0209732. PMID: 30811433.
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Dobrinskikh E, Lewis L, Brian Doctor R, Okamura K, Lee MG, Altmann C, Faubel S, Kopp JB, Blaine J. Shank2 Regulates Renal Albumin Endocytosis. Physiol Rep. 2015 Sep; 3(9). PMID: 26333830.
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Blaine J, Chonchol M, Levi M. Renal control of calcium, phosphate, and magnesium homeostasis. Clin J Am Soc Nephrol. 2015 Jul 07; 10(7):1257-72. PMID: 25287933.
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Hung KW, Blaine J, Faubel S. Dual therapy difficulties in angiotensin blockade for proteinuria: a teachable moment. JAMA Intern Med. 2014 Sep; 174(9):1429-30. PMID: 25089763.
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Carson JM, Okamura K, Wakashin H, McFann K, Dobrinskikh E, Kopp JB, Blaine J. Podocytes degrade endocytosed albumin primarily in lysosomes. PLoS One. 2014; 9(6):e99771. PMID: 24924335.
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Dobrinskikh E, Okamura K, Kopp JB, Doctor RB, Blaine J. Human podocytes perform polarized, caveolae-dependent albumin endocytosis. Am J Physiol Renal Physiol. 2014 May 01; 306(9):F941-51. PMID: 24573386.
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Okamura K, Dummer P, Kopp J, Qiu L, Levi M, Faubel S, Blaine J. Endocytosis of albumin by podocytes elicits an inflammatory response and induces apoptotic cell death. PLoS One. 2013; 8(1):e54817. PMID: 23382978.
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Blaine J, Levi M. Chronic kidney disease: Albuminuria or CKD stage as best marker of CVD in diabetes? Nat Rev Nephrol. 2012 May 29; 8(7):376-7. PMID: 22641078.
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Caldas YA, Giral H, Cortázar MA, Sutherland E, Okamura K, Blaine J, Sorribas V, Koepsell H, Levi M. Liver X receptor-activating ligands modulate renal and intestinal sodium-phosphate transporters. Kidney Int. 2011 Sep; 80(5):535-44. PMID: 21677638.
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Lanzano L, Lei T, Okamura K, Giral H, Caldas Y, Masihzadeh O, Gratton E, Levi M, Blaine J. Differential modulation of the molecular dynamics of the type IIa and IIc sodium phosphate cotransporters by parathyroid hormone. . 2011 Oct; 301(4):C850-61. PMID: 21593452.
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Giral H, Lanzano L, Caldas Y, Blaine J, Verlander JW, Lei T, Gratton E, Levi M. Role of PDZK1 protein in apical membrane expression of renal sodium-coupled phosphate transporters. J Biol Chem. 2011 Apr 29; 286(17):15032-42. PMID: 21388960.
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Blaine J, Weinman EJ, Cunningham R. The regulation of renal phosphate transport. Adv Chronic Kidney Dis. 2011 Mar; 18(2):77-84. PMID: 21406291.
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Blaine J, Lanzano L, Giral H, Caldas Y, Levi M, Gratton E, Moldovan R, Lei T. Dynamic imaging of the sodium phosphate cotransporters. Adv Chronic Kidney Dis. 2011 Mar; 18(2):145-50. PMID: 21406299.
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Blaine J, Okamura K, Giral H, Breusegem S, Caldas Y, Millard A, Barry N, Levi M. PTH-induced internalization of apical membrane NaPi2a: role of actin and myosin VI. . 2009 Dec; 297(6):C1339-46. PMID: 19776390.
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Giral H, Caldas Y, Sutherland E, Wilson P, Breusegem S, Barry N, Blaine J, Jiang T, Wang XX, Levi M. Regulation of rat intestinal Na-dependent phosphate transporters by dietary phosphate. Am J Physiol Renal Physiol. 2009 Nov; 297(5):F1466-75. PMID: 19675183.
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Breusegem SY, Takahashi H, Giral-Arnal H, Wang X, Jiang T, Verlander JW, Wilson P, Miyazaki-Anzai S, Sutherland E, Caldas Y, Blaine JT, Segawa H, Miyamoto K, Barry NP, Levi M. Differential regulation of the renal sodium-phosphate cotransporters NaPi-IIa, NaPi-IIc, and PiT-2 in dietary potassium deficiency. Am J Physiol Renal Physiol. 2009 Aug; 297(2):F350-61. PMID: 19493963.
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Levi M, Blaine J, Breusegem S, Takahashi H, Sorribas V, Barry N. Renal phosphate-wasting disorders. Adv Chronic Kidney Dis. 2006 Apr; 13(2):155-65. PMID: 16580617.
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Perry C, Blaine J, Le H, Grichtchenko II. PMA- and ANG II-induced PKC regulation of the renal Na+-HCO3- cotransporter (hkNBCe1). Am J Physiol Renal Physiol. 2006 Feb; 290(2):F417-27. PMID: 16159892.
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Blaine JT, Taylor AD, Ribera AB. Carboxyl tail region of the Kv2.2 subunit mediates novel developmental regulation of channel density. J Neurophysiol. 2004 Dec; 92(6):3446-54. PMID: 15306626.
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Blaine JT, Ribera AB. Kv2 channels form delayed-rectifier potassium channels in situ. J Neurosci. 2001 Mar 01; 21(5):1473-80. PMID: 11222637.
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Blaine JT, Ribera AB. Heteromultimeric potassium channels formed by members of the Kv2 subfamily. J Neurosci. 1998 Dec 01; 18(23):9585-93. PMID: 9822719.
This graph shows the total number of publications by year, by first, middle/unknown, or last author.
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| Year | Publications |
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| 1998 | 1 | | 2001 | 1 | | 2004 | 1 | | 2005 | 1 | | 2006 | 1 | | 2009 | 3 | | 2011 | 5 | | 2012 | 1 | | 2013 | 1 | | 2014 | 4 | | 2015 | 1 | | 2019 | 4 | | 2020 | 3 | | 2021 | 2 |
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