 Muscimol
"Muscimol" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A neurotoxic isoxazole isolated from species of AMANITA. It is obtained by decarboxylation of IBOTENIC ACID. Muscimol is a potent agonist of GABA-A RECEPTORS and is used mainly as an experimental tool in animal and tissue studies.
| Descriptor ID |
D009118
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| MeSH Number(s) |
D03.383.129.462.470 D23.946.587.587
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| Concept/Terms |
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Below are MeSH descriptors whose meaning is more general than "Muscimol".
Below are MeSH descriptors whose meaning is more specific than "Muscimol".
This graph shows the total number of publications written about "Muscimol" by people in this website by year, and whether "Muscimol" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 2002 | 0 | 1 | 1 | | 2005 | 0 | 1 | 1 | | 2007 | 0 | 1 | 1 | | 2008 | 0 | 2 | 2 | | 2009 | 0 | 2 | 2 | | 2010 | 0 | 1 | 1 | | 2011 | 0 | 3 | 3 | | 2016 | 0 | 1 | 1 | | 2022 | 0 | 1 | 1 | | 2023 | 0 | 1 | 1 |
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Below are the most recent publications written about "Muscimol" by people in Profiles.
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Wellman LL, Adkins AM, Yang L, Tang X, Sanford LD. Controllable Stress Increases Rapid Eye Movement Sleep in Rats: Regulation by the Central Nucleus of the Amygdala. J Integr Neurosci. 2023 Jul 20; 22(4):100.
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Wellman LL, Lonart G, Adkins AM, Sanford LD. Regulation of dark period sleep by the Amygdala: A microinjection and optogenetics study. Brain Res. 2022 04 15; 1781:147816.
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Foilb AR, Flyer-Adams JG, Maier SF, Christianson JP. Posterior insular cortex is necessary for conditioned inhibition of fear. Neurobiol Learn Mem. 2016 10; 134 Pt B:317-27.
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Nyhuis TJ, Masini CV, Taufer KL, Day HE, Campeau S. Reversible inactivation of rostral nucleus raphe pallidus attenuates acute autonomic responses but not their habituation to repeated audiogenic stress in rats. Stress. 2016; 19(2):248-59.
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Naik AK, Latham JR, Obradovic A, Jevtovic-Todorovic V. Dorsal root ganglion application of muscimol prevents hyperalgesia and stimulates myelin protein expression after sciatic nerve injury in rats. Anesth Analg. 2012 Mar; 114(3):674-82.
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Rozeske RR, Der-Avakian A, Watkins LR, Maier SF. Activation of the medial prefrontal cortex by escapable stress is necessary for protection against subsequent inescapable stress-induced potentiation of morphine conditioned place preference. Eur J Neurosci. 2012 Jan; 35(1):160-5.
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Christianson JP, Jennings JH, Ragole T, Flyer JG, Benison AM, Barth DS, Watkins LR, Maier SF. Safety signals mitigate the consequences of uncontrollable stress via a circuit involving the sensory insular cortex and bed nucleus of the stria terminalis. Biol Psychiatry. 2011 Sep 01; 70(5):458-64.
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Benison AM, Chumachenko S, Harrison JA, Maier SF, Falci SP, Watkins LR, Barth DS. Caudal granular insular cortex is sufficient and necessary for the long-term maintenance of allodynic behavior in the rat attributable to mononeuropathy. J Neurosci. 2011 Apr 27; 31(17):6317-28.
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Weinberg MS, Johnson DC, Bhatt AP, Spencer RL. Medial prefrontal cortex activity can disrupt the expression of stress response habituation. Neuroscience. 2010 Jul 14; 168(3):744-56.
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Christianson JP, Thompson BM, Watkins LR, Maier SF. Medial prefrontal cortical activation modulates the impact of controllable and uncontrollable stressor exposure on a social exploration test of anxiety in the rat. Stress. 2009 Sep; 12(5):445-50.
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