 Receptor, Serotonin, 5-HT2C
"Receptor, Serotonin, 5-HT2C" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A serotonin receptor subtype found primarily in the CENTRAL NERVOUS SYSTEM and the CHOROID PLEXUS. This receptor subtype is believed to mediate the anorectic action of SEROTONIN, while selective antagonists of the 5-HT2C receptor appear to induce ANXIETY. Several isoforms of this receptor subtype exist, due to adenine deaminase editing of the receptor mRNA.
| Descriptor ID |
D044405
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| MeSH Number(s) |
D12.776.543.750.670.800.200.200 D12.776.543.750.695.800.200.200 D12.776.543.750.720.850.200.200
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| Concept/Terms |
Receptor, Serotonin, 5-HT2C- Receptor, Serotonin, 5-HT2C
- 5-HT2C Receptor
- 5 HT2C Receptor
- Receptor, 5-HT2C
- 5-Hydroxytryptamine Type 2C Receptor
- 5 Hydroxytryptamine Type 2C Receptor
- Receptor, 5-Hydroxytryptamine Type 2C
- Receptor, 5 Hydroxytryptamine Type 2C
- Serotonin 2C Receptor
- Receptor, Serotonin 2C
- 5-HT(2C) Receptor
- 5-Hydroxytryptamine Type 2C Receptors
- 5 Hydroxytryptamine Type 2C Receptors
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Below are MeSH descriptors whose meaning is more general than "Receptor, Serotonin, 5-HT2C".
- Chemicals and Drugs [D]
- Amino Acids, Peptides, and Proteins [D12]
- Proteins [D12.776]
- Membrane Proteins [D12.776.543]
- Receptors, Cell Surface [D12.776.543.750]
- Receptors, Biogenic Amine [D12.776.543.750.670]
- Receptors, Serotonin [D12.776.543.750.670.800]
- Receptors, Serotonin, 5-HT2 [D12.776.543.750.670.800.200]
- Receptor, Serotonin, 5-HT2C [D12.776.543.750.670.800.200.200]
- Receptors, G-Protein-Coupled [D12.776.543.750.695]
- Receptors, Serotonin [D12.776.543.750.695.800]
- Receptors, Serotonin, 5-HT2 [D12.776.543.750.695.800.200]
- Receptor, Serotonin, 5-HT2C [D12.776.543.750.695.800.200.200]
- Receptors, Neurotransmitter [D12.776.543.750.720]
- Receptors, Serotonin [D12.776.543.750.720.850]
- Receptors, Serotonin, 5-HT2 [D12.776.543.750.720.850.200]
- Receptor, Serotonin, 5-HT2C [D12.776.543.750.720.850.200.200]
Below are MeSH descriptors whose meaning is more specific than "Receptor, Serotonin, 5-HT2C".
This graph shows the total number of publications written about "Receptor, Serotonin, 5-HT2C" by people in this website by year, and whether "Receptor, Serotonin, 5-HT2C" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 2008 | 0 | 1 | 1 | | 2009 | 1 | 0 | 1 | | 2010 | 1 | 0 | 1 | | 2011 | 1 | 0 | 1 | | 2012 | 1 | 0 | 1 | | 2013 | 0 | 1 | 1 | | 2015 | 1 | 0 | 1 |
To return to the timeline, click here.
Below are the most recent publications written about "Receptor, Serotonin, 5-HT2C" by people in Profiles.
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Baratta MV, Kodandaramaiah SB, Monahan PE, Yao J, Weber MD, Lin PA, Gisabella B, Petrossian N, Amat J, Kim K, Yang A, Forest CR, Boyden ES, Goosens KA. Stress Enables Reinforcement-Elicited Serotonergic Consolidation of Fear Memory. Biol Psychiatry. 2016 05 15; 79(10):814-822.
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Christianson JP, Greenwood BN. Stress-protective neural circuits: not all roads lead through the prefrontal cortex. Stress. 2014 Jan; 17(1):1-12.
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Greenwood BN, Strong PV, Loughridge AB, Day HE, Clark PJ, Mika A, Hellwinkel JE, Spence KG, Fleshner M. 5-HT2C receptors in the basolateral amygdala and dorsal striatum are a novel target for the anxiolytic and antidepressant effects of exercise. PLoS One. 2012; 7(9):e46118.
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Strong PV, Christianson JP, Loughridge AB, Amat J, Maier SF, Fleshner M, Greenwood BN. 5-hydroxytryptamine 2C receptors in the dorsal striatum mediate stress-induced interference with negatively reinforced instrumental escape behavior. Neuroscience. 2011 Dec 01; 197:132-44.
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Tye H, Mueller SG, Prestle J, Scheuerer S, Schindler M, Nosse B, Prevost N, Brown CJ, Heifetz A, Moeller C, Pedret-Dunn A, Whittaker M. Novel 6,7,8,9-tetrahydro-5H-1,4,7,10a-tetraaza-cyclohepta[f]indene analogues as potent and selective 5-HT(2C) agonists for the treatment of metabolic disorders. Bioorg Med Chem Lett. 2011 Jan 01; 21(1):34-7.
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Yamashita PS, de Bortoli VC, Zangrossi H. 5-HT2C receptor regulation of defensive responses in the rat dorsal periaqueductal gray. Neuropharmacology. 2011 Feb-Mar; 60(2-3):216-22.
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Christianson JP, Ragole T, Amat J, Greenwood BN, Strong PV, Paul ED, Fleshner M, Watkins LR, Maier SF. 5-hydroxytryptamine 2C receptors in the basolateral amygdala are involved in the expression of anxiety after uncontrollable traumatic stress. Biol Psychiatry. 2010 Feb 15; 67(4):339-45.
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Kawahara Y, Grimberg A, Teegarden S, Mombereau C, Liu S, Bale TL, Blendy JA, Nishikura K. Dysregulated editing of serotonin 2C receptor mRNAs results in energy dissipation and loss of fat mass. J Neurosci. 2008 Nov 26; 28(48):12834-44.
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Greenwood BN, Strong PV, Brooks L, Fleshner M. Anxiety-like behaviors produced by acute fluoxetine administration in male Fischer 344 rats are prevented by prior exercise. Psychopharmacology (Berl). 2008 Aug; 199(2):209-22.
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Du Y, Stasko M, Costa AC, Davisson MT, Gardiner KJ. Editing of the serotonin 2C receptor pre-mRNA: Effects of the Morris Water Maze. Gene. 2007 Apr 15; 391(1-2):186-97.
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