 Prolactinoma
"Prolactinoma" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A pituitary adenoma which secretes PROLACTIN, leading to HYPERPROLACTINEMIA. Clinical manifestations include AMENORRHEA; GALACTORRHEA; IMPOTENCE; HEADACHE; visual disturbances; and CEREBROSPINAL FLUID RHINORRHEA.
| Descriptor ID |
D015175
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| MeSH Number(s) |
C04.557.470.035.625 C04.588.322.609.792 C10.228.140.617.738.675.800 C19.344.609.792 C19.700.734.792
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| Concept/Terms |
Prolactinoma- Prolactinoma
- Prolactinomas
- Lactotroph Adenoma
- Adenoma, Lactotroph
- Adenomas, Lactotroph
- Lactotroph Adenomas
- Prolactinoma, Familial
- PRL-Secreting Pituitary Adenoma
- PRL Secreting Pituitary Adenoma
- PRL-Secreting Pituitary Adenomas
- Pituitary Adenoma, PRL-Secreting
- Pituitary Adenomas, PRL-Secreting
- Prolactin-Producing Pituitary Adenoma
- Pituitary Adenoma, Prolactin-Producing
- Pituitary Adenomas, Prolactin-Producing
- Prolactin Producing Pituitary Adenoma
- Prolactin-Producing Pituitary Adenomas
- Prolactin-Secreting Pituitary Adenoma
- Prolactin Secreting Pituitary Adenoma
- Adenoma, Prolactin-Secreting, Pituitary
- Pituitary Adenoma, Prolactin-Secreting
- Pituitary Adenoma, Prolactin Secreting
- Pituitary Adenomas, Prolactin-Secreting
- Prolactin-Secreting Pituitary Adenomas
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Below are MeSH descriptors whose meaning is more general than "Prolactinoma".
Below are MeSH descriptors whose meaning is more specific than "Prolactinoma".
This graph shows the total number of publications written about "Prolactinoma" by people in this website by year, and whether "Prolactinoma" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1995 | 0 | 1 | 1 | | 2000 | 0 | 1 | 1 | | 2008 | 1 | 0 | 1 | | 2011 | 1 | 0 | 1 | | 2014 | 0 | 1 | 1 | | 2018 | 1 | 0 | 1 | | 2019 | 1 | 0 | 1 |
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Below are the most recent publications written about "Prolactinoma" by people in Profiles.
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Nevzati E, Chatain GP, Carr SB, Lillehei KO, Kerr JM. Surgical management considerations in cystic prolactinomas-a single center case series. Endocrine. 2020 01; 67(1):58-66.
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Roof AK, Jirawatnotai S, Trudeau T, Kuzyk C, Wierman ME, Kiyokawa H, Gutierrez-Hartmann A. The Balance of PI3K and ERK Signaling Is Dysregulated in Prolactinoma and Modulated by Dopamine. Endocrinology. 2018 06 01; 159(6):2421-2434.
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Booth AK, Gutierrez-Hartmann A. Signaling pathways regulating pituitary lactotrope homeostasis and tumorigenesis. Adv Exp Med Biol. 2015; 846:37-59.
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Booth A, Trudeau T, Gomez C, Lucia MS, Gutierrez-Hartmann A. Persistent ERK/MAPK activation promotes lactotrope differentiation and diminishes tumorigenic phenotype. Mol Endocrinol. 2014 Dec; 28(12):1999-2011.
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Tong Y, Zhou J, Mizutani J, Fukuoka H, Ren SG, Gutierrez-Hartmann A, Koeffler HP, Melmed S. CEBPD suppresses prolactin expression and prolactinoma cell proliferation. Mol Endocrinol. 2011 Nov; 25(11):1880-91.
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Madsen H, Borges TM, Knox AJ, Michaelis KA, Xu M, Lillehei KO, Wierman ME, Kleinschmidt-DeMasters BK. Giant pituitary adenomas: pathologic-radiographic correlations and lack of role for p53 and MIB-1 labeling. Am J Surg Pathol. 2011 Aug; 35(8):1204-13.
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Smith ER, Loeffler J, Misra M, Pomerantz SR, Stemmer-Rachamimov A, Post MD. Case records of the Massachusetts General Hospital. Case 37-2008. A 17-year-old boy with a pituitary tumor and skull abnormalities. N Engl J Med. 2008 Nov 27; 359(22):2367-77.
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Clayton RN, Pfeifer M, Atkinson AB, Belchetz P, Wass JA, Kyrodimou E, Vanderpump M, Simpson D, Bicknell J, Farrell WE. Different patterns of allelic loss (loss of heterozygosity) in recurrent human pituitary tumors provide evidence for multiclonal origins. Clin Cancer Res. 2000 Oct; 6(10):3973-82.
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Kleinschmidt-DeMasters BK, Conway DR, Franklin WA, Lillehei KO, Kruse CA. Neural cell adhesion molecule expression in human pituitary adenomas. J Neurooncol. 1995; 25(3):205-13.
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Azad N, Nayyar R, Tentler J, Cernius M, Emanuele NV, Kirsteins L, Lawrence AM. Anatomical and functional effects of estrogen-induced prolactinomas on the rat hypothalamus. J Exp Pathol. 1989; 4(4):237-49.
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