Bromouracil
"Bromouracil" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
5-Bromo-2,4(1H,3H)-pyrimidinedione. Brominated derivative of uracil that acts as an antimetabolite, substituting for thymine in DNA. It is used mainly as an experimental mutagen, but its deoxyriboside (BROMODEOXYURIDINE) is used to treat neoplasms.
| Descriptor ID |
D001976
|
| MeSH Number(s) |
D03.383.742.698.875.237
|
| Concept/Terms |
Bromouracil- Bromouracil
- Bromuracil
- 5-Bromouracil
- 5 Bromouracil
|
Below are MeSH descriptors whose meaning is more general than "Bromouracil".
Below are MeSH descriptors whose meaning is more specific than "Bromouracil".
This graph shows the total number of publications written about "Bromouracil" by people in this website by year, and whether "Bromouracil" was a major or minor topic of these publications.
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Below are the most recent publications written about "Bromouracil" by people in Profiles.
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Cai H, Li Z, Conti PS. The improved syntheses of 5-substituted 2'-[18F]fluoro-2'-deoxy-arabinofuranosyluracil derivatives ([18F]FAU, [18F]FEAU, [18F]FFAU, [18F]FCAU, [18F]FBAU and [18F]FIAU) using a multistep one-pot strategy. Nucl Med Biol. 2011 Jul; 38(5):659-66.
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Alauddin MM, Shahinian A, Park R, Tohme M, Fissekis JD, Conti PS. Synthesis of 2'-deoxy-2'-[18F]fluoro-5-bromo-1-beta-D-arabinofuranosyluracil ([18F]-FBAU) and 2'-deoxy-2'-[18F]fluoro-5-chloro-1-beta-D-arabinofuranosyl-uracil ([18F]-FCAU), and their biological evaluation as markers for gene expression. Nucl Med Biol. 2004 May; 31(4):399-405.
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Goeddel DV, Yansura DG, Winston C, Caruthers MH. Studies on gene control regions. VII. Effect of 5-bromuracil-substituted lac operators on the lac operator-lac repressor interaction. J Mol Biol. 1978 Aug 25; 123(4):661-87.