Phosphatidylinositol Diacylglycerol-Lyase
"Phosphatidylinositol Diacylglycerol-Lyase" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A phosphorus-oxygen lyase found primarily in BACTERIA. The enzyme catalyzes the cleavage of a phosphoester linkage in 1-phosphatidyl-1D-myo-inositol to form 1D-myo-inositol 1,2-cyclic phosphate and diacylglycerol. The enzyme was formerly classified as a phosphoric diester hydrolase (EC 3.1.4.10) and is often referred to as a TYPE C PHOSPHOLIPASES. However it is now known that a cyclic phosphate is the final product of this enzyme and that water does not enter into the reaction.
| Descriptor ID |
D043265
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| MeSH Number(s) |
D08.811.277.352.640.700.700.500 D08.811.520.650.800
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| Concept/Terms |
Phosphatidylinositol Diacylglycerol-Lyase- Phosphatidylinositol Diacylglycerol-Lyase
- Diacylglycerol-Lyase, Phosphatidylinositol
- Phosphatidylinositol Diacylglycerol Lyase
- Monophosphatidylinositol Phosphodiesterase
- Phosphodiesterase, Monophosphatidylinositol
- 1-Phosphatidylinositol Phosphodiesterase
- 1 Phosphatidylinositol Phosphodiesterase
- Phosphodiesterase, 1-Phosphatidylinositol
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Below are MeSH descriptors whose meaning is more general than "Phosphatidylinositol Diacylglycerol-Lyase".
Below are MeSH descriptors whose meaning is more specific than "Phosphatidylinositol Diacylglycerol-Lyase".
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Below are the most recent publications written about "Phosphatidylinositol Diacylglycerol-Lyase" by people in Profiles.
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Raben DM, Jarpe MB, Leach KL. Nuclear lipid metabolism in NEST: Nuclear Envelope Signal Transduction. J Membr Biol. 1994 Oct; 142(1):1-7.
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Dreskin SC, Metzger H. Fc epsilon RI-mediated hydrolysis of phosphoinositides in ghosts derived from rat basophilic leukemia cells. J Immunol. 1991 May 01; 146(9):3102-9.
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Chien MM, Cambier JC. Divalent cation regulation of phosphoinositide metabolism. Naturally occurring B lymphoblasts contain a Mg2(+)-regulated phosphatidylinositol-specific phospholipase C. J Biol Chem. 1990 Jun 05; 265(16):9201-7.
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Campbell KS, Cambier JC. B lymphocyte antigen receptors (mIg) are non-covalently associated with a disulfide linked, inducibly phosphorylated glycoprotein complex. EMBO J. 1990 Feb; 9(2):441-8.
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Orlicky DJ, Silio M, Williams C, Gordon J, Gerschenson LE. Regulation of inositol phosphate levels by prostaglandins in cultured endometrial cells. J Cell Physiol. 1986 Jul; 128(1):105-12.