 Pulmonary Alveolar Proteinosis
"Pulmonary Alveolar Proteinosis" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A PULMONARY ALVEOLI-filling disease, characterized by dense phospholipoproteinaceous deposits in the alveoli, cough, and DYSPNEA. This disease is often related to, congenital or acquired, impaired processing of PULMONARY SURFACTANTS by alveolar macrophages, a process dependent on GRANULOCYTE-MACROPHAGE COLONY-STIMULATING FACTOR.
| Descriptor ID |
D011649
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| MeSH Number(s) |
C08.381.719
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| Concept/Terms |
Pulmonary Alveolar Proteinosis- Pulmonary Alveolar Proteinosis
- Alveolar Proteinosis, Pulmonary
- Proteinosis, Pulmonary Alveolar
- Pulmonary Alveolar Proteinoses
- Alveolar Proteinoses, Pulmonary
- Proteinoses, Pulmonary Alveolar
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Below are MeSH descriptors whose meaning is more general than "Pulmonary Alveolar Proteinosis".
Below are MeSH descriptors whose meaning is more specific than "Pulmonary Alveolar Proteinosis".
This graph shows the total number of publications written about "Pulmonary Alveolar Proteinosis" by people in this website by year, and whether "Pulmonary Alveolar Proteinosis" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 2007 | 1 | 0 | 1 | | 2008 | 1 | 0 | 1 | | 2013 | 1 | 1 | 2 | | 2017 | 2 | 0 | 2 | | 2018 | 1 | 0 | 1 | | 2019 | 1 | 0 | 1 | | 2021 | 1 | 0 | 1 | | 2022 | 1 | 0 | 1 | | 2023 | 1 | 0 | 1 | | 2024 | 1 | 0 | 1 |
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Below are the most recent publications written about "Pulmonary Alveolar Proteinosis" by people in Profiles.
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Lee E, Williams KJ, McCarthy C, Bridges JP, Redente EF, de Aguiar Vallim TQ, Barrington RA, Wang T, Tarling EJ. Alveolar macrophage lipid burden correlates with clinical improvement in patients with pulmonary alveolar proteinosis. J Lipid Res. 2024 02; 65(2):100496.
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Neehus AL, Carey B, Landekic M, Panikulam P, Deutsch G, Ogishi M, Arango-Franco CA, Philippot Q, Modaresi M, Mohammadzadeh I, Corcini Berndt M, Rinchai D, Le Voyer T, Rosain J, Momenilandi M, Martin-Fernandez M, Khan T, Bohlen J, Han JE, Deslys A, Bernard M, Gajardo-Carrasco T, Soud?e C, Le Floc'h C, Migaud M, Seeleuthner Y, Jang MS, Nikolouli E, Seyedpour S, Begueret H, Emile JF, Le Guen P, Tavazzi G, Colombo CNJ, Marzani FC, Angelini M, Trespidi F, Ghirardello S, Alipour N, Molitor A, Carapito R, Mazloomrezaei M, Rokni-Zadeh H, Changi-Ashtiani M, Brouzes C, Vargas P, Borghesi A, Lachmann N, Bahram S, Crestani B, Fayon M, Galode F, Pahari S, Schlesinger LS, Marr N, Bogunovic D, Boisson-Dupuis S, B?ziat V, Abel L, Borie R, Young LR, Deterding R, Shahrooei M, Rezaei N, Parvaneh N, Craven D, Gros P, Malo D, Sepulveda FE, Nogee LM, Aladjidi N, Trapnell BC, Casanova JL, Bustamante J. Human inherited CCR2 deficiency underlies progressive polycystic lung disease. Cell. 2024 01 18; 187(2):390-408.e23.
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Cohen RA, Rose CS, Go LHT, Zell-Baran LM, Almberg KS, Sarver EA, Lowers HA, Iwaniuk C, Clingerman SM, Richardson DL, Abraham JL, Cool CD, Franko AD, Hubbs AF, Murray J, Orandle MS, Sanyal S, Vorajee NI, Petsonk EL, Zulfikar R, Green FHY. Pathology and Mineralogy Demonstrate Respirable Crystalline Silica Is a Major Cause of Severe Pneumoconiosis in U.S. Coal Miners. Ann Am Thorac Soc. 2022 09; 19(9):1469-1478.
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Ataya A, Knight V, Carey BC, Lee E, Tarling EJ, Wang T. The Role of GM-CSF Autoantibodies in Infection and Autoimmune Pulmonary Alveolar Proteinosis: A Concise Review. Front Immunol. 2021; 12:752856.
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Anderson K, Carey B, Martin A, Roark C, Chalk C, Nowell-Bostic M, Freed B, Aubrey M, Trapnell B, Fontenot A. Pulmonary alveolar proteinosis: An autoimmune disease lacking an HLA association. PLoS One. 2019; 14(3):e0213179.
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McCarthy C, Lee E, Bridges JP, Sallese A, Suzuki T, Woods JC, Bartholmai BJ, Wang T, Chalk C, Carey BC, Arumugam P, Shima K, Tarling EJ, Trapnell BC. Statin as a novel pharmacotherapy of pulmonary alveolar proteinosis. Nat Commun. 2018 08 07; 9(1):3127.
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Trapnell BC, Bridges J. Does Granulocyte-Macrophage Colony-Stimulating Factor Coordinate a Hepatopulmonary Axis of Lipid Metabolism? Am J Respir Cell Mol Biol. 2017 10; 57(4):383-385.
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Sallese A, Suzuki T, McCarthy C, Bridges J, Filuta A, Arumugam P, Shima K, Ma Y, Wessendarp M, Black D, Chalk C, Carey B, Trapnell BC. Targeting cholesterol homeostasis in lung diseases. Sci Rep. 2017 08 31; 7(1):10211.
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Arikan-Ayyildiz Z, Caglayan-Sozmen S, Isik S, Deterding R, Dishop MK, Couderc R, Epaud R, Louha M, Uzuner N. Survival of an infant with homozygous surfactant protein C (SFTPC) mutation. Pediatr Pulmonol. 2014 Mar; 49(3):E112-5.
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Stafford M, Cappa A, Weyant M, Lara A, Ellis J, Weitzel NS, Puskas F. Treatment of acute silicoproteinosis by whole-lung lavage. Semin Cardiothorac Vasc Anesth. 2013 Jun; 17(2):152-9.
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