 Multiple Sclerosis
"Multiple Sclerosis" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
An autoimmune disorder mainly affecting young adults and characterized by destruction of myelin in the central nervous system. Pathologic findings include multiple sharply demarcated areas of demyelination throughout the white matter of the central nervous system. Clinical manifestations include visual loss, extra-ocular movement disorders, paresthesias, loss of sensation, weakness, dysarthria, spasticity, ataxia, and bladder dysfunction. The usual pattern is one of recurrent attacks followed by partial recovery (see MULTIPLE SCLEROSIS, RELAPSING-REMITTING), but acute fulminating and chronic progressive forms (see MULTIPLE SCLEROSIS, CHRONIC PROGRESSIVE) also occur. (Adams et al., Principles of Neurology, 6th ed, p903)
| Descriptor ID |
D009103
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| MeSH Number(s) |
C10.114.375.500 C10.314.350.500 C20.111.258.250.500
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| Concept/Terms |
Multiple Sclerosis- Multiple Sclerosis
- Sclerosis, Multiple
- Sclerosis, Disseminated
- Disseminated Sclerosis
- MS (Multiple Sclerosis)
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Below are MeSH descriptors whose meaning is more general than "Multiple Sclerosis".
Below are MeSH descriptors whose meaning is more specific than "Multiple Sclerosis".
This graph shows the total number of publications written about "Multiple Sclerosis" by people in this website by year, and whether "Multiple Sclerosis" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1992 | 1 | 0 | 1 | | 1994 | 1 | 0 | 1 | | 1996 | 1 | 0 | 1 | | 1997 | 6 | 0 | 6 | | 1998 | 2 | 0 | 2 | | 1999 | 2 | 0 | 2 | | 2000 | 1 | 0 | 1 | | 2001 | 4 | 0 | 4 | | 2002 | 2 | 1 | 3 | | 2003 | 8 | 0 | 8 | | 2004 | 3 | 1 | 4 | | 2005 | 15 | 0 | 15 | | 2006 | 11 | 2 | 13 | | 2007 | 14 | 1 | 15 | | 2008 | 13 | 1 | 14 | | 2009 | 15 | 0 | 15 | | 2010 | 14 | 0 | 14 | | 2011 | 15 | 2 | 17 | | 2012 | 15 | 2 | 17 | | 2013 | 8 | 3 | 11 | | 2014 | 12 | 0 | 12 | | 2015 | 8 | 0 | 8 | | 2016 | 14 | 3 | 17 | | 2017 | 17 | 2 | 19 | | 2018 | 21 | 1 | 22 | | 2019 | 13 | 1 | 14 | | 2020 | 10 | 1 | 11 |
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Below are the most recent publications written about "Multiple Sclerosis" by people in Profiles.
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Montgomery TL, Künstner A, Kennedy JJ, Fang Q, Asarian L, Culp-Hill R, D'Alessandro A, Teuscher C, Busch H, Krementsov DN. Interactions between host genetics and gut microbiota determine susceptibility to CNS autoimmunity. Proc Natl Acad Sci U S A. 2020 11 03; 117(44):27516-27527.
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Hidde MC, Howell M, DeBord A, Leach HJ. Acute High-Intensity Interval Exercise in Multiple Sclerosis with Mobility Disability. Med Sci Sports Exerc. 2020 09; 52(9):2055.
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Domen CH, Greher MR, Hosokawa PW, Barnes SL, Hoyt BD, Wodushek TR. Are Established Embedded Performance Validity Test Cut-Offs Generalizable to Patients With Multiple Sclerosis? Arch Clin Neuropsychol. 2020 Jul 24; 35(5):511-516.
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Santoro JD, Waltz M, Aaen G, Belman A, Benson L, Gorman M, Goyal MS, Graves JS, Harris Y, Krupp L, Lotze T, Mar S, Moodley M, Ness J, Rensel M, Rodriguez M, Schreiner T, Tillema JM, Waubant E, Weinstock-Guttman B, Hurtubise BF, Roalstad S, Rose J, Casper TC, Chitnis T. Pediatric Multiple Sclerosis Severity Score in a large US cohort. Neurology. 2020 09 29; 95(13):e1844-e1853.
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Kennedy PGE, Graner MW, Walker D, Pointon T, Fringuello A, Yu X. Recombinant antibodies derived from laser captured single plasma cells of multiple sclerosis brain identified phage peptides which may be used as tools for characterizing intrathecal IgG response. J Neuroimmunol. 2020 10 15; 347:577319.
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Chen JJ, Flanagan EP, Bhatti MT, Jitprapaikulsan J, Dubey D, Lopez Chiriboga ASS, Fryer JP, Weinshenker BG, McKeon A, Tillema JM, Lennon VA, Lucchinetti CF, Kunchok A, McClelland CM, Lee MS, Bennett JL, Pelak VS, Van Stavern G, Adesina OO, Eggenberger ER, Acierno MD, Wingerchuk DM, Lam BL, Moss H, Beres S, Gilbert AL, Shah V, Armstrong G, Heidary G, Cestari DM, Stiebel-Kalish H, Pittock SJ. Steroid-sparing maintenance immunotherapy for MOG-IgG associated disorder. Neurology. 2020 07 14; 95(2):e111-e120.
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Campbell JA, Jelinek GA, Weiland TJ, Nag N, Neate SL, Palmer AJ, Mulhern B, De Livera A, Simpson-Yap S. SF-6D health state utilities for lifestyle, sociodemographic and clinical characteristics of a large international cohort of people with multiple sclerosis. Qual Life Res. 2020 Sep; 29(9):2509-2527.
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Krysko KM, Graves JS, Rensel M, Weinstock-Guttman B, Rutatangwa A, Aaen G, Belman A, Benson L, Chitnis T, Gorman M, Goyal MS, Harris Y, Krupp L, Lotze T, Mar S, Moodley M, Ness J, Rodriguez M, Rose J, Schreiner T, Tillema JM, Waltz M, Casper TC, Waubant E. Real-World Effectiveness of Initial Disease-Modifying Therapies in Pediatric Multiple Sclerosis. Ann Neurol. 2020 07; 88(1):42-55.
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Mañago MM, Kline PW, Alvarez E, Christiansen CL. Trunk and pelvis movement compensation in people with multiple sclerosis: Relationships to muscle function and gait performance outcomes. Gait Posture. 2020 05; 78:48-53.
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Workman CD, Fietsam AC, Rudroff T. Associations of lower limb joint asymmetry with fatigue and disability in people with multiple sclerosis. Clin Biomech (Bristol, Avon). 2020 05; 75:104989.
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