 Multiple Sclerosis
"Multiple Sclerosis" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
An autoimmune disorder mainly affecting young adults and characterized by destruction of myelin in the central nervous system. Pathologic findings include multiple sharply demarcated areas of demyelination throughout the white matter of the central nervous system. Clinical manifestations include visual loss, extra-ocular movement disorders, paresthesias, loss of sensation, weakness, dysarthria, spasticity, ataxia, and bladder dysfunction. The usual pattern is one of recurrent attacks followed by partial recovery (see MULTIPLE SCLEROSIS, RELAPSING-REMITTING), but acute fulminating and chronic progressive forms (see MULTIPLE SCLEROSIS, CHRONIC PROGRESSIVE) also occur. (Adams et al., Principles of Neurology, 6th ed, p903)
| Descriptor ID |
D009103
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| MeSH Number(s) |
C10.114.375.500 C10.314.350.500 C20.111.258.250.500
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| Concept/Terms |
Multiple Sclerosis- Multiple Sclerosis
- Sclerosis, Multiple
- Sclerosis, Disseminated
- Disseminated Sclerosis
- MS (Multiple Sclerosis)
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Below are MeSH descriptors whose meaning is more general than "Multiple Sclerosis".
Below are MeSH descriptors whose meaning is more specific than "Multiple Sclerosis".
This graph shows the total number of publications written about "Multiple Sclerosis" by people in this website by year, and whether "Multiple Sclerosis" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1997 | 2 | 0 | 2 | | 1998 | 1 | 0 | 1 | | 2000 | 1 | 0 | 1 | | 2001 | 3 | 0 | 3 | | 2002 | 1 | 1 | 2 | | 2003 | 6 | 0 | 6 | | 2004 | 2 | 1 | 3 | | 2005 | 9 | 0 | 9 | | 2006 | 7 | 1 | 8 | | 2007 | 7 | 1 | 8 | | 2008 | 7 | 1 | 8 | | 2009 | 7 | 0 | 7 | | 2010 | 8 | 0 | 8 | | 2011 | 8 | 2 | 10 | | 2012 | 6 | 2 | 8 | | 2013 | 4 | 3 | 7 | | 2014 | 9 | 1 | 10 | | 2015 | 7 | 0 | 7 | | 2016 | 9 | 4 | 13 | | 2017 | 20 | 3 | 23 | | 2018 | 17 | 0 | 17 | | 2019 | 17 | 2 | 19 | | 2020 | 18 | 2 | 20 | | 2021 | 15 | 2 | 17 | | 2022 | 19 | 1 | 20 | | 2023 | 35 | 0 | 35 | | 2024 | 19 | 2 | 21 | | 2025 | 8 | 1 | 9 |
To return to the timeline, click here.
Below are the most recent publications written about "Multiple Sclerosis" by people in Profiles.
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O'Neill KA, Charvet L, George A, Waltz M, Casper TC, Benson L, Gorman M, Mar S, Ness J, Schreiner T, Waubant E, Weinstock-Guttman B, Wheeler Y, Ortiz R, Krupp LB. Childhood adversity in parents of patients with pediatric multiple sclerosis. Mult Scler Relat Disord. 2025 Jun; 98:106424.
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Gross PS, Dur?n-Laforet V, Ho LT, Melchor GS, Zia S, Manavi Z, Barclay WE, Lee SH, Shults N, Selva S, Alvarez E, Plemel JR, Fu MM, Schafer DP, Huang JK. Senescent-like microglia limit remyelination through the senescence associated secretory phenotype. Nat Commun. 2025 Mar 07; 16(1):2283.
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DiCillo EB, Kountikov E, Zhu M, Lanker S, Harlow DE, Piette ER, Zhang W, Hayward B, Heuler J, Korich J, Bennett JL, Pisetsky D, Tedder T. Patterns of autoantibody expression in multiple sclerosis identified through development of an autoantigen discovery technology. J Clin Invest. 2025 Mar 03; 135(5).
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Motl RW, Backus D, Hebert JR, Ng AV, McCully KK, Neal WN, Schmidt H, McBurney R, Plummer P, Bethoux F, Lowman J, Cutter G. Walking performance is worse in black than white people with multiple sclerosis. Mult Scler Relat Disord. 2025 Mar; 95:106343.
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Chang G, Sebastian P, Virupakshaiah A, Schoeps VA, Cherbuin N, Casper TC, Gorman MP, Benson LA, Chitnis T, Rensel M, Abrams AW, Lotze T, Mar SS, Schreiner TL, Wheeler YS, Rose JW, Graves J, Krupp LB, Waldman AT, Lucas R, Waubant E. Association Between Sun Exposure and Risk of Relapse in Pediatric-Onset Multiple Sclerosis. Neurol Neuroimmunol Neuroinflamm. 2025 Mar; 12(2):e200375.
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Krysko KM, Waltz M, Chitnis T, Weinstock-Guttman B, Aaen GS, Belman A, Benson LA, Gorman MP, Lotze TE, Mar SS, Moodley M, Ness JM, Rensel M, Rodriguez M, Rose JW, Edwards AR, Schreiner TL, Wheeler YS, Barney BJ, Waubant E, Casper TC, Graves JS. Study of the Association Between Menarche and Disease Course in Pediatric Multiple Sclerosis. Neurology. 2025 Feb 25; 104(4):e210213.
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Martell SG, Keye SA, Kim J, Walk A, Erdman JW, Adamson B, Motl RW, Khan NA. Exploring Differences in the Lateralized Readiness Potential in Persons With Multiple Sclerosis Compared to Healthy Controls. Psychophysiology. 2025 Feb; 62(2):e70022.
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Corboy JR, Fox RJ, Cutter G, Engebretson E, Miller A, Morgan C, Gustafson T, Goodman AD, Kannan M, Sriram S, Xia Z, Lynch S, Bowen J, Kister I. DISCOntinuation of disease-modifying therapies in MS: The DISCOMS extension trial. Mult Scler. 2025 Feb; 31(2):159-173.
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Schoeps VA, Bhargava P, Virupakshaiah A, Ladakis DC, Moseley C, Chong J, Aaen G, Graves JS, Benson L, Gorman MP, Rensel M, Abrams A, Mar S, Lotze TE, Chitnis T, Waldman A, Krupp L, Rodriguez M, Tillema JM, Rose J, Schreiner T, Qureshi F, Peterson S, Barcellos LF, Casper TC, Newman J, Borkowski K, Waubant E. Distinct plasma lipids predict axonal injury and multiple sclerosis activity. J Neurol Neurosurg Psychiatry. 2025 Jan 16; 96(2):150-157.
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Hibner BA, Lima NS, Sherman SR, Motl RW, Chirinos JA, Phillips S, Clifford PS, Reder AT, Baynard T, Fernhall B. Cardiovascular hemodynamic response to peak exercise in individuals with multiple sclerosis. Physiol Rep. 2024 Dec; 12(24):e70150.
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