 Organophosphonates
"Organophosphonates" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Carbon-containing phosphonic acid compounds. Included under this heading are compounds that have carbon bound to either OXYGEN atom or the PHOSPHOROUS atom of the (P=O)O2 structure.
| Descriptor ID |
D063065
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| MeSH Number(s) |
D02.705.429
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| Concept/Terms |
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Below are MeSH descriptors whose meaning is more general than "Organophosphonates".
Below are MeSH descriptors whose meaning is more specific than "Organophosphonates".
This graph shows the total number of publications written about "Organophosphonates" by people in this website by year, and whether "Organophosphonates" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1996 | 1 | 0 | 1 | | 1997 | 1 | 0 | 1 | | 1998 | 2 | 0 | 2 | | 1999 | 1 | 0 | 1 | | 2001 | 1 | 0 | 1 | | 2004 | 1 | 1 | 2 | | 2005 | 2 | 1 | 3 | | 2006 | 6 | 3 | 9 | | 2007 | 2 | 0 | 2 | | 2008 | 1 | 1 | 2 | | 2009 | 3 | 2 | 5 | | 2010 | 3 | 2 | 5 | | 2011 | 4 | 1 | 5 | | 2012 | 5 | 2 | 7 | | 2013 | 7 | 2 | 9 | | 2014 | 4 | 3 | 7 | | 2015 | 4 | 1 | 5 | | 2017 | 2 | 0 | 2 | | 2020 | 0 | 1 | 1 |
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Below are the most recent publications written about "Organophosphonates" by people in Profiles.
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Kumar P, Caruthers MH. DNA Analogues Modified at the Nonlinking Positions of Phosphorus. Acc Chem Res. 2020 10 20; 53(10):2152-2166.
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Chen Y, Gera L, Zhang S, Li X, Yang Y, Mamouni K, Wu AY, Liu H, Kucuk O, Wu D. Small molecule BKM1972 inhibits human prostate cancer growth and overcomes docetaxel resistance in intraosseous models. Cancer Lett. 2019 04 01; 446:62-72.
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Veleti SK, Petit C, Ronning DR, Sucheck SJ. Zwitterionic pyrrolidene-phosphonates: inhibitors of the glycoside hydrolase-like phosphorylase Streptomyces coelicolor GlgEI-V279S. Org Biomol Chem. 2017 05 10; 15(18):3884-3891.
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Zhao X, Sun K, Lan Z, Song W, Cheng L, Chi W, Chen J, Huo Y, Xu L, Liu X, Deng H, Siegenthaler JA, Chen L. Tenofovir and adefovir down-regulate mitochondrial chaperone TRAP1 and succinate dehydrogenase subunit B to metabolically reprogram glucose metabolism and induce nephrotoxicity. Sci Rep. 2017 04 11; 7:46344.
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Nguyen NV, Burgos A, Prok L. Spiny Papules in an Immunosuppressed Child. Pediatr Dermatol. 2015 Nov-Dec; 32(6):e296-7.
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Monfregola L, Caruthers MH. Solid-Phase Synthesis, Hybridizing Ability, Uptake, and Nuclease Resistant Profiles of Position-Selective Cationic and Hydrophobic Phosphotriester Oligonucleotides. J Org Chem. 2015 Sep 18; 80(18):9147-58.
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Castillo-Mancilla JR, Meditz A, Wilson C, Zheng JH, Palmer BE, Lee EJ, Gardner EM, Seifert S, Kerr B, Bushman LR, MaWhinney S, Anderson PL. Reduced immune activation during tenofovir-emtricitabine therapy in HIV-negative individuals. . 2015 Apr 15; 68(5):495-501.
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Caruso Brown AE, Cohen MN, Tong S, Braverman RS, Rooney JF, Giller R, Levin MJ. Pharmacokinetics and safety of intravenous cidofovir for life-threatening viral infections in pediatric hematopoietic stem cell transplant recipients. Antimicrob Agents Chemother. 2015 Jul; 59(7):3718-25.
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Paul S, Roy S, Monfregola L, Shang S, Shoemaker R, Caruthers MH. Oxidative substitution of boranephosphonate diesters as a route to post-synthetically modified DNA. J Am Chem Soc. 2015 Mar 11; 137(9):3253-64.
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Winston J, Chonchol M, Gallant J, Durr J, Canada RB, Liu H, Martin P, Patel K, Hindman J, Piontkowsky D. Discontinuation of tenofovir disoproxil fumarate for presumed renal adverse events in treatment-naïve HIV-1 patients: meta-analysis of randomized clinical studies. HIV Clin Trials. 2014 Nov-Dec; 15(6):231-45.
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