 Retinoic Acid Receptor alpha
"Retinoic Acid Receptor alpha" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A nuclear receptor protein which belongs to a family of transcription regulators of ligand-responsive regulatory proteins which include steroid hormone receptors. In addition to a C-terminal ligand-binding domain, these nuclear receptors contain a highly-conserved N-terminal zinc-finger domain that mediates binding ligand-responsive elements.
| Descriptor ID |
D000072482
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| MeSH Number(s) |
D12.776.826.701.250 D12.776.930.775.250
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| Concept/Terms |
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Below are MeSH descriptors whose meaning is more general than "Retinoic Acid Receptor alpha".
Below are MeSH descriptors whose meaning is more specific than "Retinoic Acid Receptor alpha".
This graph shows the total number of publications written about "Retinoic Acid Receptor alpha" by people in this website by year, and whether "Retinoic Acid Receptor alpha" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 1997 | 0 | 1 | 1 | | 2007 | 0 | 1 | 1 | | 2008 | 0 | 2 | 2 | | 2009 | 0 | 1 | 1 | | 2013 | 0 | 1 | 1 | | 2016 | 1 | 1 | 2 | | 2017 | 1 | 0 | 1 |
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Below are the most recent publications written about "Retinoic Acid Receptor alpha" by people in Profiles.
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Fettig LM, McGinn O, Finlay-Schultz J, LaBarbera DV, Nordeen SK, Sartorius CA. Cross talk between progesterone receptors and retinoic acid receptors in regulation of cytokeratin 5-positive breast cancer cells. Oncogene. 2017 11 02; 36(44):6074-6084.
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Bonney S, Harrison-Uy S, Mishra S, MacPherson AM, Choe Y, Li D, Jaminet SC, Fruttiger M, Pleasure SJ, Siegenthaler JA. Diverse Functions of Retinoic Acid in Brain Vascular Development. J Neurosci. 2016 07 20; 36(29):7786-801.
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Nichol JN, Galbraith MD, Kleinman CL, Espinosa JM, Miller WH. NPM and BRG1 Mediate Transcriptional Resistance to Retinoic Acid in Acute Promyelocytic Leukemia. Cell Rep. 2016 Mar 29; 14(12):2938-49.
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Xu S, Sun AQ, Suchy FJ. A novel RARa/CAR-mediated mechanism for regulation of human organic solute transporter-? gene expression. Am J Physiol Gastrointest Liver Physiol. 2014 Jan; 306(2):G154-62.
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Galvin KC, Dyck L, Marshall NA, Stefanska AM, Walsh KP, Moran B, Higgins SC, Dungan LS, Mills KH. Blocking retinoic acid receptor-a enhances the efficacy of a dendritic cell vaccine against tumours by suppressing the induction of regulatory T cells. Cancer Immunol Immunother. 2013 Jul; 62(7):1273-82.
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Wang A, Alimova IN, Luo P, Jong A, Triche TJ, Wu L. Loss of CAK phosphorylation of RAR{alpha} mediates transcriptional control of retinoid-induced cancer cell differentiation. FASEB J. 2010 Mar; 24(3):833-43.
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Aoto J, Nam CI, Poon MM, Ting P, Chen L. Synaptic signaling by all-trans retinoic acid in homeostatic synaptic plasticity. Neuron. 2008 Oct 23; 60(2):308-20.
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Maghsoodi B, Poon MM, Nam CI, Aoto J, Ting P, Chen L. Retinoic acid regulates RARalpha-mediated control of translation in dendritic RNA granules during homeostatic synaptic plasticity. Proc Natl Acad Sci U S A. 2008 Oct 14; 105(41):16015-20.
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Su EJ, Cheng YH, Chatterton RT, Lin ZH, Yin P, Reierstad S, Innes J, Bulun SE. Regulation of 17-beta hydroxysteroid dehydrogenase type 2 in human placental endothelial cells. Biol Reprod. 2007 Sep; 77(3):517-25.
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Attar PS, Wertz PW, McArthur M, Imakado S, Bickenbach JR, Roop DR. Inhibition of retinoid signaling in transgenic mice alters lipid processing and disrupts epidermal barrier function. Mol Endocrinol. 1997 Jun; 11(6):792-800.
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