 Fatty Acid Desaturases
"Fatty Acid Desaturases" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A family of enzymes that catalyze the stereoselective, regioselective, or chemoselective syn-dehydrogenation reactions. They function by a mechanism that is linked directly to reduction of molecular OXYGEN.
| Descriptor ID |
D044943
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| MeSH Number(s) |
D08.811.682.690.708.392
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| Concept/Terms |
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Below are MeSH descriptors whose meaning is more general than "Fatty Acid Desaturases".
Below are MeSH descriptors whose meaning is more specific than "Fatty Acid Desaturases".
This graph shows the total number of publications written about "Fatty Acid Desaturases" by people in this website by year, and whether "Fatty Acid Desaturases" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 2000 | 0 | 1 | 1 | | 2004 | 0 | 1 | 1 | | 2005 | 0 | 1 | 1 | | 2006 | 1 | 0 | 1 | | 2010 | 1 | 0 | 1 | | 2011 | 1 | 1 | 2 | | 2012 | 1 | 0 | 1 | | 2013 | 1 | 1 | 2 | | 2014 | 3 | 0 | 3 | | 2015 | 0 | 1 | 1 | | 2017 | 1 | 1 | 2 | | 2018 | 1 | 0 | 1 | | 2019 | 2 | 0 | 2 | | 2020 | 4 | 0 | 4 | | 2021 | 3 | 0 | 3 |
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Below are the most recent publications written about "Fatty Acid Desaturases" by people in Profiles.
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Yang C, Hallmark B, Chai JC, O'Connor TD, Reynolds LM, Wood AC, Seeds M, Chen YI, Steffen LM, Tsai MY, Kaplan RC, Daviglus ML, Mandarino LJ, Fretts AM, Lemaitre RN, Coletta DK, Blomquist SA, Johnstone LM, Tontsch C, Qi Q, Ruczinski I, Rich SS, Mathias RA, Chilton FH, Manichaikul A. Impact of Amerind ancestry and FADS genetic variation on omega-3 deficiency and cardiometabolic traits in Hispanic populations. Commun Biol. 2021 07 28; 4(1):918.
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Thomas T, Cendali F, Fu X, Gamboni F, Morrison EJ, Beirne J, Nemkov T, Antonelou MH, Kriebardis A, Welsby I, Hay A, Dziewulska KH, Busch MP, Kleinman S, Buehler PW, Spitalnik SL, Zimring JC, D'Alessandro A. Fatty acid desaturase activity in mature red blood cells and implications for blood storage quality. Transfusion. 2021 06; 61(6):1867-1883.
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Zec MM, Krga I, Stojkovic L, ?ivkovic M, Pokimica B, Stankovic A, Glibetic M. Is There a FADS2-Modulated Link between Long-Chain Polyunsaturated Fatty Acids in Plasma Phospholipids and Polyphenol Intake in Adult Subjects Who Are Overweight? Nutrients. 2021 Jan 21; 13(2).
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Reynolds LM, Dutta R, Seeds MC, Lake KN, Hallmark B, Mathias RA, Howard TD, Chilton FH. FADS genetic and metabolomic analyses identify the ?5 desaturase (FADS1) step as a critical control point in the formation of biologically important lipids. Sci Rep. 2020 09 28; 10(1):15873.
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Zec MM, Stojkovic L, Zekovic M, Pokimica B, Zivkovic M, Stankovic A, Glibetic M. FADS2 polymorphisms are associated with plasma arachidonic acid and estimated desaturase-5 activity in a cross-sectional study. Nutr Res. 2020 11; 83:49-62.
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Sergeant S, Hallmark B, Mathias RA, Mustin TL, Ivester P, Bohannon ML, Ruczinski I, Johnstone L, Seeds MC, Chilton FH. Prospective clinical trial examining the impact of genetic variation in FADS1 on the metabolism of linoleic acid- and ?-linolenic acid-containing botanical oils. Am J Clin Nutr. 2020 05 01; 111(5):1068-1078.
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Boyle KE, Magill-Collins MJ, Newsom SA, Janssen RC, Friedman JE. Maternal Fat-1 Transgene Protects Offspring from Excess Weight Gain, Oxidative Stress, and Reduced Fatty Acid Oxidation in Response to High-Fat Diet. Nutrients. 2020 Mar 14; 12(3).
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Knez M, Pantovic A, Zekovic M, Pavlovic Z, Glibetic M, Zec M. Is There a Link between Zinc Intake and Status with Plasma Fatty Acid Profile and Desaturase Activities in Dyslipidemic Subjects? Nutrients. 2019 Dec 28; 12(1).
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Harris DN, Ruczinski I, Yanek LR, Becker LC, Becker DM, Guio H, Cui T, Chilton FH, Mathias RA, O'Connor TD. Evolution of Hominin Polyunsaturated Fatty Acid Metabolism: From Africa to the New World. Genome Biol Evol. 2019 05 01; 11(5):1417-1430.
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Reynolds LM, Howard TD, Ruczinski I, Kanchan K, Seeds MC, Mathias RA, Chilton FH. Tissue-specific impact of FADS cluster variants on FADS1 and FADS2 gene expression. PLoS One. 2018; 13(3):e0194610.
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