 Timolol
"Timolol" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A beta-adrenergic antagonist similar in action to PROPRANOLOL. The levo-isomer is the more active. Timolol has been proposed as an antihypertensive, antiarrhythmic, antiangina, and antiglaucoma agent. It is also used in the treatment of MIGRAINE DISORDERS and tremor.
| Descriptor ID |
D013999
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| MeSH Number(s) |
D02.033.100.624.915 D02.033.755.624.915 D02.092.063.624.915 D02.886.675.867.768 D03.383.129.708.867.768 D03.383.533.640.775
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| Concept/Terms |
Timolol- Timolol
- (S)-1-((1,1-Dimethylethyl)amino)-3-((4-(4-morpholinyl)-1,2,5-thiadazol-3-yl)oxy)-2-propanol
- Timolol Hemihydrate
- Hemihydrate, Timolol
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Below are MeSH descriptors whose meaning is more general than "Timolol".
Below are MeSH descriptors whose meaning is more specific than "Timolol".
This graph shows the total number of publications written about "Timolol" by people in this website by year, and whether "Timolol" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 2007 | 1 | 1 | 2 | | 2009 | 1 | 0 | 1 | | 2011 | 2 | 2 | 4 | | 2014 | 1 | 0 | 1 | | 2017 | 1 | 0 | 1 | | 2019 | 0 | 1 | 1 |
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Below are the most recent publications written about "Timolol" by people in Profiles.
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Kahook MY, Serle JB, Mah FS, Kim T, Raizman MB, Heah T, Ramirez-Davis N, Kopczynski CC, Usner DW, Novack GD. Long-term Safety and Ocular Hypotensive Efficacy Evaluation of Netarsudil Ophthalmic Solution: Rho Kinase Elevated IOP Treatment Trial (ROCKET-2). Am J Ophthalmol. 2019 04; 200:130-137.
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Seibold LK, DeWitt PE, Kroehl ME, Kahook MY. The 24-Hour Effects of Brinzolamide/Brimonidine Fixed Combination and Timolol on Intraocular Pressure and Ocular Perfusion Pressure. J Ocul Pharmacol Ther. 2017 04; 33(3):161-169.
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Konstas AG, Voudouragkaki IC, Boboridis KG, Haidich AB, Paschalinou E, Giannopoulos T, Dragoumis ND, Makridis AK, Kahook MY. 24-hour efficacy of travoprost/timolol BAK-free versus latanoprost/timolol fixed combinations in patients insufficiently controlled with latanoprost. Adv Ther. 2014 Jun; 31(6):592-603.
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Kahook MY, Fechtner RD, Katz LJ, Noecker RJ, Ammar DA. A comparison of active ingredients and preservatives between brand name and generic topical glaucoma medications using liquid chromatography-tandem mass spectrometry. Curr Eye Res. 2012 Feb; 37(2):101-8.
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Holden CA, Tyagi P, Thakur A, Kadam R, Jadhav G, Kompella UB, Yang H. Polyamidoamine dendrimer hydrogel for enhanced delivery of antiglaucoma drugs. Nanomedicine. 2012 Jul; 8(5):776-83.
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Ammar DA, Kahook MY. Effects of benzalkonium chloride- or polyquad-preserved fixed combination glaucoma medications on human trabecular meshwork cells. Mol Vis. 2011; 17:1806-13.
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Ammar DA, Noecker RJ, Kahook MY. Effects of benzalkonium chloride- and polyquad-preserved combination glaucoma medications on cultured human ocular surface cells. Adv Ther. 2011 Jun; 28(6):501-10.
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Ammar DA, Kahook MY. The effects of combination glaucoma medications on ocular surface epithelial cells. Adv Ther. 2009 Oct; 26(10):970-5.
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Sontheimer D, Hitchcock K, Saseen J. Clinical inquiries. Are there big differences among beta-blockers in treating essential hypertension? J Fam Pract. 2007 Apr; 56(4):312-4.
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Noecker RJ, Awadallah NS, Kahook MY. Travoprost 0.004%/timolol 0.5% fixed combination. Drugs Today (Barc). 2007 Feb; 43(2):77-83.
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