Isoxazoles
"Isoxazoles" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Azoles with an OXYGEN and a NITROGEN next to each other at the 1,2 positions, in contrast to OXAZOLES that have nitrogens at the 1,3 positions.
Descriptor ID |
D007555
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MeSH Number(s) |
D03.383.129.385
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Concept/Terms |
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Below are MeSH descriptors whose meaning is more general than "Isoxazoles".
Below are MeSH descriptors whose meaning is more specific than "Isoxazoles".
This graph shows the total number of publications written about "Isoxazoles" by people in this website by year, and whether "Isoxazoles" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
Year | Major Topic | Minor Topic | Total |
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2001 | 1 | 1 | 2 | 2003 | 1 | 1 | 2 | 2006 | 3 | 1 | 4 | 2008 | 1 | 1 | 2 | 2010 | 1 | 0 | 1 | 2011 | 1 | 1 | 2 | 2012 | 2 | 0 | 2 | 2013 | 1 | 0 | 1 | 2015 | 1 | 3 | 4 | 2017 | 0 | 1 | 1 | 2018 | 1 | 0 | 1 | 2020 | 1 | 0 | 1 | 2021 | 1 | 0 | 1 | 2022 | 0 | 1 | 1 |
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Below are the most recent publications written about "Isoxazoles" by people in Profiles.
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Duncan NS, Campbell MJ, Backos DS, Li C, Rider KC, Stump S, Weaver MJ, Gajewski MP, Beall HD, Reigan P, Natale NR. 10-Alkoxy-anthracenyl-isoxazole analogs have sub-micromolar activity against a Glioblastoma multiforme cell line. Bioorg Med Chem. 2022 Sep 01; 69:116911.
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El Kasmi KC, Ghosh S, Anderson AL, Devereaux MW, Balasubramaniyan N, D'Alessandro A, Orlicky DJ, Suchy FJ, Shearn CT, Sokol RJ. Pharmacologic activation of hepatic farnesoid X receptor prevents parenteral nutrition-associated cholestasis in mice. Hepatology. 2022 02; 75(2):252-265.
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Weaver MJ, Stump S, Campbell MJ, Backos DS, Li C, Reigan P, Adams E, Beall HD, Natale NR. 10-N-heterocylic aryl-isoxazole-amides (AIMs) have robust anti-tumor activity against breast and brain cancer cell lines and useful fluorescence properties. Bioorg Med Chem. 2020 11 15; 28(22):115781.
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Gates C, Backos DS, Reigan P, Kang HJ, Koerner C, Mirzaei J, Natale NR. Isoxazolo[3,4-d]pyridazinones positively modulate the metabotropic glutamate subtypes 2 and 4. Bioorg Med Chem. 2018 09 15; 26(17):4797-4803.
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Steiger SA, Li C, Backos DS, Reigan P, Natale NR. Dimeric isoxazolyl-1,4-dihydropyridines have enhanced binding at the multi-drug resistance transporter. Bioorg Med Chem. 2017 06 15; 25(12):3223-3234.
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Kim G, Barner JC, Rascati K, Richards K. Examining Time to Initiation of Biologic Disease-modifying Antirheumatic Drugs and Medication Adherence and Persistence Among Texas Medicaid Recipients With Rheumatoid Arthritis. Clin Ther. 2016 Mar; 38(3):646-54.
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Laub M, Fraser R, Kurche J, Lara A, Kiser TH, Reynolds PM. Use of a Cholestyramine Washout in a Patient With Septic Shock on Leflunomide Therapy: A Case Report and Review of the Literature. J Intensive Care Med. 2016 Jul; 31(6):412-4.
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González MI, Grabenstatter HL, Cea-Del Rio CA, Cruz Del Angel Y, Carlsen J, Laoprasert RP, White AM, Huntsman MM, Brooks-Kayal A. Seizure-related regulation of GABAA receptors in spontaneously epileptic rats. Neurobiol Dis. 2015 May; 77:246-56.
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Stevens KE, Zheng L, Floyd KL, Stitzel JA. Maximizing the effect of an a7 nicotinic receptor PAM in a mouse model of schizophrenia-like sensory inhibition deficits. Brain Res. 2015 Jun 22; 1611:8-17.
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Root DH, Hoffman AF, Good CH, Zhang S, Gigante E, Lupica CR, Morales M. Norepinephrine activates dopamine D4 receptors in the rat lateral habenula. J Neurosci. 2015 Feb 25; 35(8):3460-9.
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