 GTP-Binding Protein beta Subunits
"GTP-Binding Protein beta Subunits" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Heterotrimeric GTP-binding protein subunits that tightly associate with GTP-BINDING PROTEIN GAMMA SUBUNITS. A dimer of beta and gamma subunits is formed when the GTP-BINDING PROTEIN ALPHA SUBUNIT dissociates from the GTP-binding protein heterotrimeric complex. The beta-gamma dimer can play an important role in signal transduction by interacting with a variety of second messengers.
| Descriptor ID |
D044387
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| MeSH Number(s) |
D12.644.360.360.520 D12.776.157.325.332.520 D12.776.476.375.520 D12.776.543.325.450
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| Concept/Terms |
GTP-Binding Protein beta Subunits- GTP-Binding Protein beta Subunits
- GTP Binding Protein beta Subunits
- G-Protein beta Subunit
- G Protein beta Subunit
- Subunit, G-Protein beta
- beta Subunit, G-Protein
- GTP-Binding Protein beta Subunit
- GTP Binding Protein beta Subunit
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Below are MeSH descriptors whose meaning is more general than "GTP-Binding Protein beta Subunits".
Below are MeSH descriptors whose meaning is more specific than "GTP-Binding Protein beta Subunits".
This graph shows the total number of publications written about "GTP-Binding Protein beta Subunits" by people in this website by year, and whether "GTP-Binding Protein beta Subunits" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
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| 2004 | 0 | 2 | 2 | | 2007 | 0 | 1 | 1 | | 2010 | 0 | 2 | 2 | | 2011 | 1 | 0 | 1 | | 2012 | 1 | 0 | 1 | | 2013 | 0 | 1 | 1 | | 2016 | 1 | 0 | 1 | | 2017 | 1 | 0 | 1 | | 2018 | 1 | 0 | 1 |
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Below are the most recent publications written about "GTP-Binding Protein beta Subunits" by people in Profiles.
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Schultz-Rogers L, Masuho I, Pinto E Vairo F, Schmitz CT, Schwab TL, Clark KJ, Gunderson L, Pichurin PN, Wierenga K, Martemyanov KA, Klee EW. Haploinsufficiency as a disease mechanism in GNB1-associated neurodevelopmental disorder. Mol Genet Genomic Med. 2020 11; 8(11):e1477.
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Gulati S, Jin H, Masuho I, Orban T, Cai Y, Pardon E, Martemyanov KA, Kiser PD, Stewart PL, Ford CP, Steyaert J, Palczewski K. Targeting G protein-coupled receptor signaling at the G protein level with a selective nanobody inhibitor. Nat Commun. 2018 05 18; 9(1):1996.
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Paudyal P, Xie Q, Vaddi PK, Henry MD, Chen S. Inhibiting G protein ?? signaling blocks prostate cancer progression and enhances the efficacy of paclitaxel. Oncotarget. 2017 May 30; 8(22):36067-36081.
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Kamal FA, Travers JG, Schafer AE, Ma Q, Devarajan P, Blaxall BC. G Protein-Coupled Receptor-G-Protein ??-Subunit Signaling Mediates Renal Dysfunction and Fibrosis in Heart Failure. J Am Soc Nephrol. 2017 Jan; 28(1):197-208.
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Li F, Ponissery-Saidu S, Yee KK, Wang H, Chen ML, Iguchi N, Zhang G, Jiang P, Reisert J, Huang L. Heterotrimeric G protein subunit G?13 is critical to olfaction. J Neurosci. 2013 May 01; 33(18):7975-84.
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Loo L, Shepherd AJ, Mickle AD, Lorca RA, Shutov LP, Usachev YM, Mohapatra DP. The C-type natriuretic peptide induces thermal hyperalgesia through a noncanonical G??-dependent modulation of TRPV1 channel. J Neurosci. 2012 Aug 29; 32(35):11942-55.
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Gospe SM, Baker SA, Kessler C, Brucato MF, Winter JR, Burns ME, Arshavsky VY. Membrane attachment is key to protecting transducin GTPase-activating complex from intracellular proteolysis in photoreceptors. J Neurosci. 2011 Oct 12; 31(41):14660-8.
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Saba LM, Bennett B, Hoffman PL, Barcomb K, Ishii T, Kechris K, Tabakoff B. A systems genetic analysis of alcohol drinking by mice, rats and men: influence of brain GABAergic transmission. Neuropharmacology. 2011 Jun; 60(7-8):1269-80.
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Khan SY, McLaughlin NJ, Kelher MR, Eckels P, Gamboni-Robertson F, Banerjee A, Silliman CC. Lysophosphatidylcholines activate G2A inducing G(ai)?1-/G(aq/)11- Ca?(+) flux, G(??)-Hck activation and clathrin/?-arrestin-1/GRK6 recruitment in PMNs. Biochem J. 2010 Nov 15; 432(1):35-45.
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Thapliyal A, Bannister RA, Hanks C, Adams BA. The monomeric G proteins AGS1 and Rhes selectively influence Galphai-dependent signaling to modulate N-type (CaV2.2) calcium channels. Am J Physiol Cell Physiol. 2008 Nov; 295(5):C1417-26.
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