 Melatonin
"Melatonin" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A biogenic amine that is found in animals and plants. In mammals, melatonin is produced by the PINEAL GLAND. Its secretion increases in darkness and decreases during exposure to light. Melatonin is implicated in the regulation of SLEEP, mood, and REPRODUCTION. Melatonin is also an effective antioxidant.
| Descriptor ID |
D008550
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| MeSH Number(s) |
D03.633.100.473.914.481 D06.472.506
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| Concept/Terms |
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Below are MeSH descriptors whose meaning is more general than "Melatonin".
Below are MeSH descriptors whose meaning is more specific than "Melatonin".
This graph shows the total number of publications written about "Melatonin" by people in this website by year, and whether "Melatonin" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1991 | 1 | 0 | 1 | | 1994 | 2 | 1 | 3 | | 1997 | 1 | 0 | 1 | | 1999 | 0 | 2 | 2 | | 2000 | 2 | 1 | 3 | | 2001 | 0 | 2 | 2 | | 2002 | 1 | 1 | 2 | | 2003 | 3 | 0 | 3 | | 2004 | 4 | 1 | 5 | | 2005 | 2 | 0 | 2 | | 2006 | 2 | 2 | 4 | | 2007 | 0 | 3 | 3 | | 2008 | 0 | 1 | 1 | | 2009 | 1 | 0 | 1 | | 2010 | 1 | 2 | 3 | | 2011 | 0 | 2 | 2 | | 2012 | 1 | 0 | 1 | | 2013 | 1 | 1 | 2 | | 2014 | 1 | 4 | 5 | | 2015 | 2 | 3 | 5 | | 2016 | 2 | 0 | 2 | | 2017 | 1 | 1 | 2 | | 2018 | 1 | 3 | 4 | | 2019 | 2 | 1 | 3 | | 2020 | 0 | 1 | 1 | | 2021 | 1 | 0 | 1 |
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Below are the most recent publications written about "Melatonin" by people in Profiles.
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Cogswell D, Bisesi P, Markwald RR, Cruickshank-Quinn C, Quinn K, McHill A, Melanson EL, Reisdorph N, Wright KP, Depner CM. Identification of a Preliminary Plasma Metabolome-based Biomarker for Circadian Phase in Humans. J Biol Rhythms. 2021 08; 36(4):369-383.
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Stothard ER, Ritchie HK, Birks BR, Eckel RH, Higgins J, Melanson EL, Wright KP, McHill AW. Early Morning Food Intake as a Risk Factor for Metabolic Dysregulation. Nutrients. 2020 Mar 13; 12(3).
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Lee SE, Koh H, Joo DJ, Nedumaran B, Jeon HJ, Park CS, Harris RA, Kim YD. Induction of SIRT1 by melatonin improves alcohol-mediated oxidative liver injury by disrupting the CRBN-YY1-CYP2E1 signaling pathway. J Pineal Res. 2020 Apr; 68(3):e12638.
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Rahman SA, Wright KP, Lockley SW, Czeisler CA, Gronfier C. Characterizing the temporal Dynamics of Melatonin and Cortisol Changes in Response to Nocturnal Light Exposure. Sci Rep. 2019 12 23; 9(1):19720.
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Simon SL, McWhirter L, Diniz Behn C, Bubar KM, Kaar JL, Pyle L, Rahat H, Garcia-Reyes Y, Carreau AM, Wright KP, Nadeau KJ, Cree-Green M. Morning Circadian Misalignment Is Associated With Insulin Resistance in Girls With Obesity and Polycystic Ovarian Syndrome. J Clin Endocrinol Metab. 2019 08 01; 104(8):3525-3534.
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Pierce M, Linnebur SA, Pearson SM, Fixen DR. Optimal Melatonin Dose in Older Adults: A Clinical Review of the Literature. Sr Care Pharm. 2019 Jul 01; 34(7):419-431.
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Simon SL, Behn CD, Cree-Green M, Kaar JL, Pyle L, Hawkins SMM, Rahat H, Garcia-Reyes Y, Wright KP, Nadeau KJ. Too Late and Not Enough: School Year Sleep Duration, Timing, and Circadian Misalignment Are Associated with Reduced Insulin Sensitivity in Adolescents with Overweight/Obesity. J Pediatr. 2019 02; 205:257-264.e1.
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Depner CM, Melanson EL, McHill AW, Wright KP. Mistimed food intake and sleep alters 24-hour time-of-day patterns of the human plasma proteome. Proc Natl Acad Sci U S A. 2018 06 05; 115(23):E5390-E5399.
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Akacem LD, Wright KP, LeBourgeois MK. Sensitivity of the circadian system to evening bright light in preschool-age children. Physiol Rep. 2018 03; 6(5).
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Lichtblau KR, Romani PW, Greer BD, Fisher WW, Bragdon AK. Remote treatment of sleep-related trichotillomania and trichophagia. J Appl Behav Anal. 2018 04; 51(2):255-262.
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