 Brain Death
"Brain Death" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A state of prolonged irreversible cessation of all brain activity, including lower brain stem function with the complete absence of voluntary movements, responses to stimuli, brain stem reflexes, and spontaneous respirations. Reversible conditions which mimic this clinical state (e.g., sedative overdose, hypothermia, etc.) are excluded prior to making the determination of brain death. (From Adams et al., Principles of Neurology, 6th ed, pp348-9)
| Descriptor ID |
D001926
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| MeSH Number(s) |
C10.228.140.151 C10.597.606.358.800.200.100 C23.550.260.159
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| Concept/Terms |
Brain Death- Brain Death
- Death, Brain
- Brain Dead
- Brain Deads
- Coma Depasse
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Below are MeSH descriptors whose meaning is more general than "Brain Death".
Below are MeSH descriptors whose meaning is more specific than "Brain Death".
This graph shows the total number of publications written about "Brain Death" by people in this website by year, and whether "Brain Death" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1992 | 0 | 1 | 1 | | 1993 | 2 | 1 | 3 | | 1995 | 1 | 0 | 1 | | 1998 | 0 | 2 | 2 | | 2002 | 0 | 1 | 1 | | 2005 | 0 | 1 | 1 | | 2009 | 0 | 1 | 1 | | 2010 | 1 | 0 | 1 | | 2011 | 0 | 1 | 1 | | 2016 | 3 | 1 | 4 | | 2018 | 1 | 0 | 1 | | 2019 | 2 | 0 | 2 |
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Below are the most recent publications written about "Brain Death" by people in Profiles.
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Jager NM, van Zanden JE, Subías M, Leuvenink HGD, Daha MR, Rodríguez de Córdoba S, Poppelaars F, Seelen MA. Blocking Complement Factor B Activation Reduces Renal Injury and Inflammation in a Rat Brain Death Model. Front Immunol. 2019; 10:2528.
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Prin M, Quinsey C, Kadyaudzu C, Hadar E, Charles A. Brain death in low-income countries: a report from Malawi. Trop Doct. 2019 Apr; 49(2):107-112.
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Poppelaars F, Jager NM, Kotimaa J, Leuvenink HGD, Daha MR, van Kooten C, Seelen MA, Damman J. C1-Inhibitor Treatment Decreases Renal Injury in an Established Brain-Dead Rat Model. Transplantation. 2018 01; 102(1):79-87.
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Poppelaars F, Seelen MA. Complement-mediated inflammation and injury in brain dead organ donors. Mol Immunol. 2017 04; 84:77-83.
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Scalea JR, Redfield RR, Arpali E, Leverson GE, Bennett RJ, Anderson ME, Kaufman DB, Fernandez LA, D'Alessandro AM, Foley DP, Mezrich JD. Does DCD Donor Time-to-Death Affect Recipient Outcomes? Implications of Time-to-Death at a High-Volume Center in the United States. Am J Transplant. 2017 01; 17(1):191-200.
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Nandi D, Miyamoto SD, Pietra BA, Shaddy RE, Rossano JW. Donation after circulatory death in pediatric patients: Current utilization in the United States. J Heart Lung Transplant. 2016 09; 35(9):1131-2.
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D'alessandro A, Nemkov T, Moore HB, Moore EE, Wither M, Nydam T, Slaughter A, Silliman CC, Banerjee A, Hansen KC. Metabolomics of trauma-associated death: shared and fluid-specific features of human plasma vs lymph. Blood Transfus. 2016 05; 14(2):185-94.
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Nixon JL, Kfoury AG, Brunisholz K, Horne BD, Myrick C, Miller DV, Budge D, Bader F, Everitt M, Saidi A, Stehlik J, Schmidt TC, Alharethi R. Impact of high-dose inotropic donor support on early myocardial necrosis and outcomes in cardiac transplantation. Clin Transplant. 2012 Mar-Apr; 26(2):322-7.
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Brody A, Kashuk JL, Moore EE, Beauchamp K, Barnett C, Biffl WL, Burlew CC, Johnson JL, Sauaia A. Fatal gunshot wounds to the head: a critical appraisal of organ donation rates. Am J Surg. 2010 Dec; 200(6):728-33; discussion 733.
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Saidi RF, Bradley J, Greer D, Luskin R, O'Connor K, Delmonico F, Kennealey P, Pathan F, Schuetz C, Elias N, Ko DS, Kawai T, Hertl M, Cosimi AB, Markmann JF. Changing pattern of organ donation at a single center: are potential brain dead donors being lost to donation after cardiac death? Am J Transplant. 2010 Nov; 10(11):2536-40.
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