 Gray Platelet Syndrome
"Gray Platelet Syndrome" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A rare, inherited platelet disorder characterized by a selective deficiency in the number and contents of platelet alpha-granules. It is associated with THROMBOCYTOPENIA, enlarged platelets, and prolonged bleeding time.
| Descriptor ID |
D055652
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| MeSH Number(s) |
C15.378.140.427 C16.320.099.417
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| Concept/Terms |
Gray Platelet Syndrome- Gray Platelet Syndrome
- Gray Platelet Syndromes
- Syndrome, Gray Platelet
- Syndromes, Gray Platelet
- Grey Platelet Syndrome
- Grey Platelet Syndromes
- Platelet Syndromes, Grey
- Syndrome, Grey Platelet
Platelet alpha-Granule Deficiency- Platelet alpha-Granule Deficiency
- Platelet alpha Granule Deficiency
- Platelet alpha-Granule Deficiencies
- alpha-Granule Deficiencies, Platelet
- alpha-Granule Deficiency, Platelet
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Below are MeSH descriptors whose meaning is more general than "Gray Platelet Syndrome".
Below are MeSH descriptors whose meaning is more specific than "Gray Platelet Syndrome".
This graph shows the total number of publications written about "Gray Platelet Syndrome" by people in this website by year, and whether "Gray Platelet Syndrome" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 2011 | 2 | 0 | 2 | | 2015 | 0 | 1 | 1 |
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Below are the most recent publications written about "Gray Platelet Syndrome" by people in Profiles.
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Tomberg K, Khoriaty R, Westrick RJ, Fairfield HE, Reinholdt LG, Brodsky GL, Davizon-Castillo P, Ginsburg D, Di Paola J. Spontaneous 8bp Deletion in Nbeal2 Recapitulates the Gray Platelet Syndrome in Mice. PLoS One. 2016; 11(3):e0150852.
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Settecase F, Nicholson AD, Amans MR, Higashida RT, Halbach VV, Cooke DL, Dowd CF, Hetts SW. Onyx embolization of an intraosseous pseudoaneurysm of the middle meningeal artery in a patient with meningiomatosis, McCune-Albright syndrome, and gray platelet syndrome. J Neurosurg Pediatr. 2016 Mar; 17(3):324-9.
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Kahr WH, Lo RW, Li L, Pluthero FG, Christensen H, Ni R, Vaezzadeh N, Hawkins CE, Weyrich AS, Di Paola J, Landolt-Marticorena C, Gross PL. Abnormal megakaryocyte development and platelet function in Nbeal2(-/-) mice. Blood. 2013 Nov 07; 122(19):3349-58.
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Di Paola J, Johnson J. Thrombocytopenias due to gray platelet syndrome or THC2 mutations. Semin Thromb Hemost. 2011 Sep; 37(6):690-7.
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Kahr WH, Hinckley J, Li L, Schwertz H, Christensen H, Rowley JW, Pluthero FG, Urban D, Fabbro S, Nixon B, Gadzinski R, Storck M, Wang K, Ryu GY, Jobe SM, Schutte BC, Moseley J, Loughran NB, Parkinson J, Weyrich AS, Di Paola J. Mutations in NBEAL2, encoding a BEACH protein, cause gray platelet syndrome. Nat Genet. 2011 Jul 17; 43(8):738-40.
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Fabbro S, Kahr WH, Hinckley J, Wang K, Moseley J, Ryu GY, Nixon B, White JG, Bair T, Schutte B, Di Paola J. Homozygosity mapping with SNP arrays confirms 3p21 as a recessive locus for gray platelet syndrome and narrows the interval significantly. Blood. 2011 Mar 24; 117(12):3430-4.
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