 Craniopharyngioma
"Craniopharyngioma" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A benign pituitary-region neoplasm that originates from Rathke's pouch. The two major histologic and clinical subtypes are adamantinous (or classical) craniopharyngioma and papillary craniopharyngioma. The adamantinous form presents in children and adolescents as an expanding cystic lesion in the pituitary region. The cystic cavity is filled with a black viscous substance and histologically the tumor is composed of adamantinomatous epithelium and areas of calcification and necrosis. Papillary craniopharyngiomas occur in adults, and histologically feature a squamous epithelium with papillations. (From Joynt, Clinical Neurology, 1998, Ch14, p50)
| Descriptor ID |
D003397
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| MeSH Number(s) |
C04.557.465.625.200 C04.557.580.625.200
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| Concept/Terms |
Craniopharyngioma- Craniopharyngioma
- Craniopharyngiomas
- Neoplasm, Rathke's Cleft
- Neoplasm, Rathkes Cleft
- Rathke's Pouch Tumor
- Rathkes Pouch Tumor
- Tumor, Rathke's Pouch
- Rathke Pouch Tumor
- Tumor, Rathke Pouch
- Rathke's Cleft Neoplasm
- Rathkes Cleft Neoplasm
- Neoplasm, Rathke Cleft
- Rathke Cleft Neoplasm
Craniopharyngioma, Papillary- Craniopharyngioma, Papillary
- Craniopharyngiomas, Papillary
- Papillary Craniopharyngioma
- Papillary Craniopharyngiomas
Craniopharyngioma, Child- Craniopharyngioma, Child
- Child Craniopharyngioma
- Child Craniopharyngiomas
- Craniopharyngiomas, Child
Craniopharyngioma, Adamantinous- Craniopharyngioma, Adamantinous
- Adamantinous Craniopharyngioma
- Adamantinous Craniopharyngiomas
- Craniopharyngiomas, Adamantinous
Craniopharyngioma, Adult- Craniopharyngioma, Adult
- Adult Craniopharyngioma
- Adult Craniopharyngiomas
- Craniopharyngiomas, Adult
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Below are MeSH descriptors whose meaning is more general than "Craniopharyngioma".
Below are MeSH descriptors whose meaning is more specific than "Craniopharyngioma".
This graph shows the total number of publications written about "Craniopharyngioma" by people in this website by year, and whether "Craniopharyngioma" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1997 | 1 | 0 | 1 | | 2000 | 1 | 0 | 1 | | 2002 | 1 | 0 | 1 | | 2004 | 0 | 1 | 1 | | 2005 | 1 | 0 | 1 | | 2007 | 1 | 0 | 1 | | 2009 | 1 | 0 | 1 | | 2012 | 1 | 0 | 1 | | 2014 | 1 | 0 | 1 | | 2015 | 1 | 0 | 1 | | 2016 | 1 | 0 | 1 | | 2017 | 2 | 0 | 2 | | 2018 | 2 | 0 | 2 | | 2019 | 2 | 0 | 2 | | 2020 | 4 | 0 | 4 | | 2021 | 1 | 0 | 1 |
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Below are the most recent publications written about "Craniopharyngioma" by people in Profiles.
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Hankinson TC. Editorial: Characteristics and overall survival in pediatric versus adult craniopharyngioma: a population-based study. Childs Nerv Syst. 2021 06; 37(6):1823-1824.
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Prince EW, Whelan R, Mirsky DM, Stence N, Staulcup S, Klimo P, Anderson RCE, Niazi TN, Grant G, Souweidane M, Johnston JM, Jackson EM, Limbrick DD, Smith A, Drapeau A, Chern JJ, Kilburn L, Ginn K, Naftel R, Dudley R, Tyler-Kabara E, Jallo G, Handler MH, Jones K, Donson AM, Foreman NK, Hankinson TC. Robust deep learning classification of adamantinomatous craniopharyngioma from limited preoperative radiographic images. Sci Rep. 2020 10 09; 10(1):16885.
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Whelan R, Hengartner A, Folzenlogen Z, Prince E, Hankinson TC. Adamantinomatous craniopharyngioma in the molecular age and the potential of targeted therapies: a review. Childs Nerv Syst. 2020 08; 36(8):1635-1642.
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Prince E, Whelan R, Donson A, Staulcup S, Hengartner A, Vijmasi T, Agwu C, Lillehei KO, Foreman NK, Johnston JM, Massimi L, Anderson RCE, Souweidane MM, Naftel RP, Limbrick DD, Grant G, Niazi TN, Dudley R, Kilburn L, Jackson EM, Jallo GI, Ginn K, Smith A, Chern JJ, Lee A, Drapeau A, Krieger MD, Handler MH, Hankinson TC. Transcriptional analyses of adult and pediatric adamantinomatous craniopharyngioma reveals similar expression signatures regarding potential therapeutic targets. Acta Neuropathol Commun. 2020 05 13; 8(1):68.
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Hengartner AC, Prince E, Vijmasi T, Hankinson TC. Adamantinomatous craniopharyngioma: moving toward targeted therapies. Neurosurg Focus. 2020 01 01; 48(1):E7.
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Dahl NA, Pratt D, Camelo-Piragua S, Kumar-Sinha C, Mody RJ, Septer S, Hankinson TC, Chinnaiyan AM, Koschmann C, Hoffman L. Pediatric craniopharyngioma in association with familial adenomatous polyposis. Fam Cancer. 2019 07; 18(3):327-330.
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Norris GA, Garcia J, Hankinson TC, Handler M, Foreman N, Mirsky D, Stence N, Dorris K, Green AL. Diagnostic accuracy of neuroimaging in pediatric optic chiasm/sellar/suprasellar tumors. Pediatr Blood Cancer. 2019 06; 66(6):e27680.
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Coy S, Rashid R, Lin JR, Du Z, Donson AM, Hankinson TC, Foreman NK, Manley PE, Kieran MW, Reardon DA, Sorger PK, Santagata S. Multiplexed immunofluorescence reveals potential PD-1/PD-L1 pathway vulnerabilities in craniopharyngioma. Neuro Oncol. 2018 07 05; 20(8):1101-1112.
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Apps JR, Carreno G, Gonzalez-Meljem JM, Haston S, Guiho R, Cooper JE, Manshaei S, Jani N, Hölsken A, Pettorini B, Beynon RJ, Simpson DM, Fraser HC, Hong Y, Hallang S, Stone TJ, Virasami A, Donson AM, Jones D, Aquilina K, Spoudeas H, Joshi AR, Grundy R, Storer LCD, Korbonits M, Hilton DA, Tossell K, Thavaraj S, Ungless MA, Gil J, Buslei R, Hankinson T, Hargrave D, Goding C, Andoniadou CL, Brogan P, Jacques TS, Williams HJ, Martinez-Barbera JP. Tumour compartment transcriptomics demonstrates the activation of inflammatory and odontogenic programmes in human adamantinomatous craniopharyngioma and identifies the MAPK/ERK pathway as a novel therapeutic target. Acta Neuropathol. 2018 05; 135(5):757-777.
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Donson AM, Apps J, Griesinger AM, Amani V, Witt DA, Anderson RCE, Niazi TN, Grant G, Souweidane M, Johnston JM, Jackson EM, Kleinschmidt-DeMasters BK, Handler MH, Tan AC, Gore L, Virasami A, Gonzalez-Meljem JM, Jacques TS, Martinez-Barbera JP, Foreman NK, Hankinson TC. Molecular Analyses Reveal Inflammatory Mediators in the Solid Component and Cyst Fluid of Human Adamantinomatous Craniopharyngioma. J Neuropathol Exp Neurol. 2017 Sep 01; 76(9):779-788.
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