 Hematopoietic Stem Cells
"Hematopoietic Stem Cells" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Progenitor cells from which all blood cells derived. They are found primarily in the bone marrow and also in small numbers in the peripheral blood.
| Descriptor ID |
D006412
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| MeSH Number(s) |
A11.148.378 A11.872.378 A15.378.316.378
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| Concept/Terms |
Hematopoietic Stem Cells- Hematopoietic Stem Cells
- Progenitor Cells, Hematopoietic
- Hematopoietic Progenitor Cells
- Cell, Hematopoietic Progenitor
- Cells, Hematopoietic Progenitor
- Hematopoietic Progenitor Cell
- Progenitor Cell, Hematopoietic
- Stem Cells, Hematopoietic
- Cell, Hematopoietic Stem
- Cells, Hematopoietic Stem
- Hematopoietic Stem Cell
- Stem Cell, Hematopoietic
Colony-Forming Units, Hematopoietic- Colony-Forming Units, Hematopoietic
- Colony Forming Units, Hematopoietic
- Colony-Forming Unit, Hematopoietic
- Hematopoietic Colony-Forming Unit
- Hematopoietic Colony-Forming Units
- Unit, Hematopoietic Colony-Forming
- Units, Hematopoietic Colony-Forming
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Below are MeSH descriptors whose meaning is more general than "Hematopoietic Stem Cells".
Below are MeSH descriptors whose meaning is more specific than "Hematopoietic Stem Cells".
This graph shows the total number of publications written about "Hematopoietic Stem Cells" by people in this website by year, and whether "Hematopoietic Stem Cells" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1995 | 5 | 1 | 6 | | 1996 | 7 | 1 | 8 | | 1997 | 3 | 2 | 5 | | 1998 | 2 | 1 | 3 | | 1999 | 3 | 3 | 6 | | 2000 | 3 | 0 | 3 | | 2001 | 6 | 2 | 8 | | 2002 | 5 | 4 | 9 | | 2003 | 5 | 2 | 7 | | 2004 | 6 | 3 | 9 | | 2005 | 3 | 4 | 7 | | 2006 | 3 | 3 | 6 | | 2007 | 6 | 2 | 8 | | 2008 | 2 | 1 | 3 | | 2009 | 7 | 2 | 9 | | 2010 | 5 | 1 | 6 | | 2011 | 13 | 9 | 22 | | 2012 | 4 | 1 | 5 | | 2013 | 11 | 4 | 15 | | 2014 | 12 | 3 | 15 | | 2015 | 3 | 4 | 7 | | 2016 | 6 | 5 | 11 | | 2017 | 3 | 4 | 7 | | 2018 | 7 | 3 | 10 | | 2019 | 7 | 1 | 8 | | 2020 | 7 | 6 | 13 | | 2021 | 11 | 4 | 15 | | 2022 | 3 | 4 | 7 | | 2023 | 6 | 2 | 8 | | 2024 | 4 | 5 | 9 | | 2025 | 5 | 3 | 8 |
To return to the timeline, click here.
Below are the most recent publications written about "Hematopoietic Stem Cells" by people in Profiles.
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Kirmani S, Huan T, Van Amburg JC, Joehanes R, Uddin MM, Nguyen NQH, Yu B, Brody JA, Fornage M, Bressler J, Sotoodehnia N, Ong DA, Puddu F, Floyd JS, Ballantyne CM, Psaty BM, Raffield LM, Natarajan P, Conneely KN, Weinstock JS, Carson AP, Lange LA, Ferrier K, Heard-Costa NL, Murabito J, Bick AG, Levy D. Epigenome-wide DNA methylation association study of CHIP provides insight into perturbed gene regulation. Nat Commun. 2025 May 20; 16(1):4678.
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Young KA, Hosseini M, Mistry JJ, Morganti C, Mills TS, Cai X, James BT, Nye GJ, Fournier NR, Voisin V, Chegini A, Schimmer AD, Bader GD, Egan G, Mansour MR, Challen GA, Pietras EM, Fisher-Wellman KH, Ito K, Chan SM, Trowbridge JJ. Elevated mitochondrial membrane potential is a therapeutic vulnerability in Dnmt3a-mutant clonal hematopoiesis. Nat Commun. 2025 Apr 16; 16(1):3306.
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Nesbitt NM, Araldi GL, Pennacchia L, Marchenko N, Assar Z, Muzzarelli KM, Thekke Veedu RR, Medel-Lacruz B, Lee E, Eisenmesser EZ, Kreitler DF, Bahou WF. Small molecule BLVRB redox inhibitor promotes megakaryocytopoiesis and stress thrombopoiesis in vivo. Nat Commun. 2025 Apr 11; 16(1):3480.
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Darmusey L, Bagley AJ, Nguyen TT, Carlson HL, Blaylock H, Shrestha SB, Pang A, Tauchmann S, Taylor SC, Foley AC, Ni?o KE, Pietras EM, Braun TP, Maxson JE. Dual ASXL1 and CSF3R mutations drive myeloid-biased stem cell expansion and enhance neutrophil differentiation. Blood Adv. 2025 Apr 08; 9(7):1593-1607.
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Feist WN, Luna SE, Ben-Efraim K, Filsinger Interrante MV, Amorin A, Johnston NM, Bruun TUJ, Utz A, Ghanim HY, Lesch BJ, McLaughlin TM, Dudek AM, Porteus MH. Multilayered HIV-1 resistance in HSPCs through CCR5 Knockout and B cell secretion of HIV-inhibiting antibodies. Nat Commun. 2025 Apr 01; 16(1):3103.
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Itkin T, Houghton S, Schreiner R, Lin Y, Badwe CR, Voisin V, Murison A, Seyedhassantehrani N, Kaufmann KB, Garcia-Prat L, Booth GT, Geng F, Liu Y, Gomez-Salinero JM, Shieh JH, Redmond D, Xiang JZ, Josefowicz SZ, Trapnell C, Pietras EM, Spencer JA, Levine R, Xiao W, Zangi L, Hadland B, Dick JE, Xie SZ, Rafii S. Transcriptional activation of regenerative hematopoiesis via microenvironmental sensing. Nat Immunol. 2025 Mar; 26(3):378-390.
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Toghani D, Gupte S, Zeng S, Mahammadov E, Crosse EI, Seyedhassantehrani N, Burns C, Gravano D, Radtke S, Kiem HP, Rodriguez S, Carlesso N, Pradeep A, Georgiades A, Lucas F, Wilson NK, Kinston SJ, G?ttgens B, Zong L, Beerman I, Park B, Janssens DH, Jones D, Toghani A, Nerlov C, Pietras EM, Mesnieres M, Maes C, Kumanogoh A, Worzfeld T, Cheong JG, Josefowicz SZ, Kharchenko P, Scadden DT, Scialdone A, Spencer JA, Silberstein L. Niche-derived Semaphorin 4A safeguards functional identity of myeloid-biased hematopoietic stem cells. Nat Aging. 2025 Apr; 5(4):558-575.
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Kent A, Yee Mon KJ, Hutchins Z, Putzel G, Zhigarev D, Grier A, Jia B, Kortlever RM, Barbet G, Evan GI, Blander JM. A stromal inflammasome Ras safeguard against Myc-driven lymphomagenesis. Nat Immunol. 2025 Jan; 26(1):53-67.
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Voit RA, Liao X, Caulier A, Antoszewski M, Cohen B, Armant M, Lu HY, Fleming TJ, Kamal E, Wahlster L, Roche AM, Everett JK, Petrichenko A, Huang MM, Clarke W, Myers KC, Forester C, Perez-Atayde A, Bushman FD, Pellin D, Shimamura A, Williams DA, Sankaran VG. Regulated GATA1 expression as a universal gene therapy for Diamond-Blackfan anemia. Cell Stem Cell. 2025 Jan 02; 32(1):38-52.e6.
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Mills TS, Kain B, Burchill MA, Danis E, Lucas ED, Culp-Hill R, Cowan CM, Schleicher WE, Patel SB, Tran BT, Cao R, Goodspeed A, Ferrara S, Bevers S, Jir?n Tamburini BA, Roede JR, D'Alessandro A, King KY, Pietras EM. A distinct metabolic and epigenetic state drives trained immunity in HSC-derived macrophages from autoimmune mice. Cell Stem Cell. 2024 Nov 07; 31(11):1630-1649.e8.
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