| 
																	
																		 
																		 Wet Macular Degeneration
 
																		 
																		
																	 
																		 
																		
																	 
																			
																					
	"Wet Macular Degeneration" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, 
	MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure, 
	which enables searching at various levels of specificity.
 
	
	
		
			
			
				A form of RETINAL DEGENERATION in which abnormal CHOROIDAL NEOVASCULARIZATION occurs under the RETINA and MACULA LUTEA, causing bleeding and leaking of fluid. This leads to bulging and or lifting of the macula and the distortion or destruction of central vision.
    
			 
				
				
					
						| Descriptor ID | D057135 |  
						| MeSH Number(s) | C11.768.585.439.622 |  
						| Concept/Terms | Wet Macular DegenerationWet Macular DegenerationDegeneration, Wet MacularDegenerations, Wet MacularMacular Degeneration, WetMacular Degenerations, WetWet Macular Degenerations
 |  
				Below are MeSH descriptors whose meaning is more general than "Wet Macular Degeneration". 
				Below are MeSH descriptors whose meaning is more specific than "Wet Macular Degeneration". 
	
	
		
			
			
					
				This graph shows the total number of publications written about "Wet Macular Degeneration" by people in this website by year, and whether "Wet Macular Degeneration" was a major or minor topic of these publications.  
					  To see the data from this visualization as text, click here. 
		            | Year | Major Topic | Minor Topic | Total | 
|---|
 | 2010 | 1 | 0 | 1 |  | 2012 | 1 | 0 | 1 |  | 2013 | 1 | 0 | 1 |  | 2016 | 1 | 0 | 1 |  | 2019 | 2 | 0 | 2 |  | 2020 | 1 | 0 | 1 |  | 2021 | 0 | 1 | 1 |  | 2023 | 3 | 0 | 3 |  | 2024 | 0 | 2 | 2 |  | 2025 | 2 | 0 | 2 | 
 
                    To return to the timeline, click here. 
				Below are the most recent publications written about "Wet Macular Degeneration" by people in Profiles. 		
					
								
								Lynch AM, Grove NC, Wagner BD, Palestine AG, Holers VM, Frazer-Abel AA, Gnanaraj R, Lisker-Cervantes A, Patnaik JL, de Carlo Forest TE, Auer EA, McReynolds AJ, Mathias MT, Manoharan N, Rodriquez De Cordoba S, Mandava N. Dynamic Risk of Systemic Complement Activation With Time to Progression to Advanced Age-Related Macular Degeneration. JAMA Ophthalmol. 2025 Aug 01; 143(8):634-642.
								Gnanaraj R, Lisker-Cervantes A, Patnaik J, Rajeswaren V, Mehta N, Gange W, Lynch AM, Palestine A, Mathias M, Manoharan N, Mandava N, Forest TEC. Multimodal imaging biomarkers for progression from intermediate to advanced age-related macular degeneration (AMD): a 10-year prospective longitudinal cohort study from the University of Colorado AMD registry. BMJ Open Ophthalmol. 2025 Apr 05; 10(1).
								Borchert GA, Kiire CA, Stone NM, Akil H, Gkika T, Fischer MD, Xue K, Cehajic-Kapetanovic J, MacLaren RE, Charbel Issa P, Downes SM, De Silva SR. Real-world six-month outcomes in patients switched to faricimab following partial response to anti-VEGF therapy for neovascular age-related macular degeneration and diabetic macular oedema. Eye (Lond). 2024 Dec; 38(18):3569-3577.
								Lisker-Cervantes A, Gill Z, Gnanaraj R, Rajeswaren V, Mehta N, Gange B, Patnaik JL, Lynch AM, Palestine AG, Mathias M, Manoharan N, Mandava N, de Carlo Forest TE. Differences in imaging biomarkers between patients with intermediate and advanced non-neovascular age-related macular degeneration (AMD) in the University of Colorado AMD registry. Eur J Ophthalmol. 2025 Jan; 35(1):276-282.
								Babapoor-Farrokhran S, Qin Y, Flores-Bellver M, Niu Y, Bhutto IA, Aparicio-Domingo S, Guo C, Rodrigues M, Domashevich T, Deshpande M, Megarity H, Chopde R, Eberhart CG, Canto-Soler V, Montaner S, Sodhi A. Pathologic vs. protective roles of hypoxia-inducible factor 1 in RPE and photoreceptors in wet vs. dry age-related macular degeneration. Proc Natl Acad Sci U S A. 2023 Dec 12; 120(50):e2302845120.
								Smith SE, Lynch AM, Auer EA, Bol KA, Christopher KL, Mandava N, Patnaik JL. Visual Functioning and Mortality of Age-Related Macular Degeneration Patients in a Colorado Cohort. Ophthalmol Retina. 2023 11; 7(11):982-989.
								Droho S, Rajesh A, Cuda CM, Perlman H, Lavine JA. CD11c+ macrophages are proangiogenic and necessary for experimental choroidal neovascularization. JCI Insight. 2023 04 10; 8(7).
								Droho S, Perlman H, Lavine JA. Dendritic cells play no significant role in the laser-induced choroidal neovascularization model. Sci Rep. 2021 08 26; 11(1):17254.
								Patnaik JL, Lynch AM, Pecen PE, Jasso M, Hanson K, Mathias MT, Palestine AG, Mandava N. The impact of advanced age-related macular degeneration on the National Eye Institute's Visual Function Questionnaire-25. Acta Ophthalmol. 2021 Nov; 99(7):750-755.
								Lynch AM, Mandava N, Patnaik JL, Frazer-Abel AA, Wagner BD, Palestine AG, Mathias MT, Siringo FS, Cathcart JN, Holers VM. Systemic activation of the complement system in patients with advanced age-related macular degeneration. Eur J Ophthalmol. 2020 Sep; 30(5):1061-1068. | 
																	
																		
																			
																					People  People who have written about this concept._ 
    
        Similar Concepts   
        People who have written about this concept.
     _ 
    
        Top Journals   
        Top journals in which articles about this concept have been published.
     |