Colorado PROFILES, The Colorado Clinical and Translational Sciences Institute (CCTSI)
Keywords
Last Name
Institution

Contact Us
If you have any questions or feedback please contact us.

Kelly S. Doran

TitleProfessor
InstitutionUniversity of Colorado Denver - Anschutz Medical Campus
DepartmentSOM-Immunology Microbiology
Phone303/724-3539

    Collapse Research 
    Collapse research activities and funding
    R01NS051247     (DORAN, KELLY S)Apr 1, 2005 - Mar 31, 2016
    NIH/NINDS
    Blood-brain barrier in bacterial meningitis
    Role: Principal Investigator

    R56NS051247     (DORAN, KELLY S)Jul 13, 2006 - Jul 31, 2017
    NIH/NINDS
    Blood-Brain Barrier failure during bacterial meningitis
    Role: Principal Investigator

    R03AI123877     (DORAN, KELLY S)Feb 10, 2016 - Jan 31, 2018
    NIH/NIAID
    Development of a Probiotic Therapy for Limiting Group B Streptococcal Vaginal Carriage
    Role: Principal Investigator

    Collapse Bibliographic 
    Collapse selected publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
    List All   |   Timeline
    1. Lazzarin M, Mu R, Fabbrini M, Ghezzo C, Rinaudo CD, Doran KS, Margarit I. Contribution of pilus type 2b to invasive disease caused by a Streptococcus agalactiae ST-17 strain. BMC Microbiol. 2017 Jul 03; 17(1):148. PMID: 28673237.
      View in: PubMed
    2. Lin AE, Autran CA, Szyszka A, Escajadillo T, Huang M, Godula K, Prudden AR, Boons GJ, Lewis AL, Doran KS, Nizet V, Bode L. Human milk oligosaccharides inhibit growth of group B Streptococcus. J Biol Chem. 2017 Jul 07; 292(27):11243-11249. PMID: 28416607.
      View in: PubMed
    3. Lozano-Pope I, Sharma A, Matthias M, Doran KS, Obonyo M. Effect of myeloid differentiation primary response gene 88 on expression profiles of genes during the development and progression of Helicobacter-induced gastric cancer. BMC Cancer. 2017 Feb 15; 17(1):133. PMID: 28201999.
      View in: PubMed
    4. Hancock BM, Doran KS. Importance of strain lineages for Group B streptococcal survival. Virulence. 2016 Dec 29; 1-3. PMID: 28033037.
      View in: PubMed
    5. Patras KA, Doran KS. A Murine Model of Group B Streptococcus Vaginal Colonization. J Vis Exp. 2016 Nov 16; (117). PMID: 27911391.
      View in: PubMed
    6. Mu R, Cutting AS, Del Rosario Y, Villarino N, Stewart L, Weston TA, Patras KA, Doran KS. Identification of CiaR Regulated Genes That Promote Group B Streptococcal Virulence and Interaction with Brain Endothelial Cells. PLoS One. 2016; 11(4):e0153891. PMID: 27100296; PMCID: PMC4839699.
    7. Doran KS, Fulde M, Gratz N, Kim BJ, Nau R, Prasadarao N, Schubert-Unkmeir A, Tuomanen EI, Valentin-Weigand P. Host-pathogen interactions in bacterial meningitis. Acta Neuropathol. 2016 Feb; 131(2):185-209. PMID: 26744349; PMCID: PMC4713723.
    8. Klionsky DJ, Abdelmohsen K, Abe A, Abedin MJ, Abeliovich H, Acevedo Arozena A, Adachi H, Adams CM, Adams PD, Adeli K, Adhihetty PJ, Adler SG, Agam G, Agarwal R, Aghi MK, Agnello M, Agostinis P, Aguilar PV, Aguirre-Ghiso J, Airoldi EM, Ait-Si-Ali S, Akematsu T, Akporiaye ET, Al-Rubeai M, Albaiceta GM, Albanese C, Albani D, Albert ML, Aldudo J, Algül H, Alirezaei M, Alloza I, Almasan A, Almonte-Beceril M, Alnemri ES, Alonso C, Altan-Bonnet N, Altieri DC, Alvarez S, Alvarez-Erviti L, Alves S, Amadoro G, Amano A, Amantini C, Ambrosio S, Amelio I, Amer AO, Amessou M, Amon A, An Z, Anania FA, Andersen SU, Andley UP, Andreadi CK, Andrieu-Abadie N, Anel A, Ann DK, Anoopkumar-Dukie S, Antonioli M, Aoki H, Apostolova N, Aquila S, Aquilano K, Araki K, Arama E, Aranda A, Araya J, Arcaro A, Arias E, Arimoto H, Ariosa AR, Armstrong JL, Arnould T, Arsov I, Asanuma K, Askanas V, Asselin E, Atarashi R, Atherton SS, Atkin JD, Attardi LD, Auberger P, Auburger G, Aurelian L, Autelli R, Avagliano L, Avantaggiati ML, Avrahami L, Awale S, Azad N, Bachetti T, Backer JM, Bae DH, Bae JS, Bae ON, Bae SH, Baehrecke EH, Baek SH, Baghdiguian S, Bagniewska-Zadworna A, Bai H, Bai J, Bai XY, Bailly Y, Balaji KN, Balduini W, Ballabio A, Balzan R, Banerjee R, Bánhegyi G, Bao H, Barbeau B, Barrachina MD, Barreiro E, Bartel B, Bartolomé A, Bassham DC, Bassi MT, Bast RC, Basu A, Batista MT, Batoko H, Battino M, Bauckman K, Baumgarner BL, Bayer KU, Beale R, Beaulieu JF, Beck GR, Becker C, Beckham JD, Bédard PA, Bednarski PJ, Begley TJ, Behl C, Behrends C, Behrens GM, Behrns KE, Bejarano E, Belaid A, Belleudi F, Bénard G, Berchem G, Bergamaschi D, Bergami M, Berkhout B, Berliocchi L, Bernard A, Bernard M, Bernassola F, Bertolotti A, Bess AS, Besteiro S, Bettuzzi S, Bhalla S, Bhattacharyya S, Bhutia SK, Biagosch C, Bianchi MW, Biard-Piechaczyk M, Billes V, Bincoletto C, Bingol B, Bird SW, Bitoun M, Bjedov I, Blackstone C, Blanc L, Blanco GA, Blomhoff HK, Boada-Romero E, Böckler S, Boes M, Boesze-Battaglia K, Boise LH, Bolino A, Boman A, Bonaldo P, Bordi M, Bosch J, Botana LM, Botti J, Bou G, Bouché M, Bouchecareilh M, Boucher MJ, Boulton ME, Bouret SG, Boya P, Boyer-Guittaut M, Bozhkov PV, Brady N, Braga VM, Brancolini C, Braus GH, Bravo-San Pedro JM, Brennan LA, Bresnick EH, Brest P, Bridges D, Bringer MA, Brini M, Brito GC, Brodin B, Brookes PS, Brown EJ, Brown K, Broxmeyer HE, Bruhat A, Brum PC, Brumell JH, Brunetti-Pierri N, Bryson-Richardson RJ, Buch S, Buchan AM, Budak H, Bulavin DV, Bultman SJ, Bultynck G, Bumbasirevic V, Burelle Y, Burke RE, Burmeister M, Bütikofer P, Caberlotto L, Cadwell K, Cahova M, Cai D, Cai J, Cai Q, Calatayud S, Camougrand N, Campanella M, Campbell GR, Campbell M, Campello S, Candau R, Caniggia I, Cantoni L, Cao L, Caplan AB, Caraglia M, Cardinali C, Cardoso SM, Carew JS, Carleton LA, Carlin CR, Carloni S, Carlsson SR, Carmona-Gutierrez D, Carneiro LA, Carnevali O, Carra S, Carrier A, Carroll B, Casas C, Casas J, Cassinelli G, Castets P, Castro-Obregon S, Cavallini G, Ceccherini I, Cecconi F, Cederbaum AI, Ceña V, Cenci S, Cerella C, Cervia D, Cetrullo S, Chaachouay H, Chae HJ, Chagin AS, Chai CY, Chakrabarti G, Chamilos G, Chan EY, Chan MT, Chandra D, Chandra P, Chang CP, Chang RC, Chang TY, Chatham JC, Chatterjee S, Chauhan S, Che Y, Cheetham ME, Cheluvappa R, Chen CJ, Chen G, Chen GC, Chen G, Chen H, Chen JW, Chen JK, Chen M, Chen M, Chen P, Chen Q, Chen Q, Chen SD, Chen S, Chen SS, Chen W, Chen WJ, Chen WQ, Chen W, Chen X, Chen YH, Chen YG, Chen Y, Chen Y, Chen Y, Chen YJ, Chen YQ, Chen Y, Chen Z, Chen Z, Cheng A, Cheng CH, Cheng H, Cheong H, Cherry S, Chesney J, Cheung CH, Chevet E, Chi HC, Chi SG, Chiacchiera F, Chiang HL, Chiarelli R, Chiariello M, Chieppa M, Chin LS, Chiong M, Chiu GN, Cho DH, Cho SG, Cho WC, Cho YY, Cho YS, Choi AM, Choi EJ, Choi EK, Choi J, Choi ME, Choi SI, Chou TF, Chouaib S, Choubey D, Choubey V, Chow KC, Chowdhury K, Chu CT, Chuang TH, Chun T, Chung H, Chung T, Chung YL, Chwae YJ, Cianfanelli V, et al. Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition). Autophagy. 2016; 12(1):1-222. PMID: 26799652; PMCID: PMC4835977 [Available on 01/21/17].
    9. Sin J, Andres AM, Taylor DJ, Weston T, Hiraumi Y, Stotland A, Kim BJ, Huang C, Doran KS, Gottlieb RA. Mitophagy is required for mitochondrial biogenesis and myogenic differentiation of C2C12 myoblasts. Autophagy. 2016; 12(2):369-80. PMID: 26566717; PMCID: PMC4836019.
    10. Torres PJ, Fletcher EM, Gibbons SM, Bouvet M, Doran KS, Kelley ST. Characterization of the salivary microbiome in patients with pancreatic cancer. PeerJ. 2015; 3:e1373. PMID: 26587342; PMCID: PMC4647550.
    11. Capp R, West DR, Doran K, Sauaia A, Wiler J, Coolman T, Ginde AA. Characteristics of Medicaid-Covered Emergency Department Visits Made by Nonelderly Adults: A National Study. J Emerg Med. 2015 Dec; 49(6):984-9. PMID: 26482830; PMCID: PMC4656066 [Available on 12/01/16].
    12. Patras KA, Wescombe PA, Rösler B, Hale JD, Tagg JR, Doran KS. Streptococcus salivarius K12 Limits Group B Streptococcus Vaginal Colonization. Infect Immun. 2015 Sep; 83(9):3438-44. PMID: 26077762; PMCID: PMC4534663.
    13. Stoner TD, Weston TA, Trejo J, Doran KS. Group B streptococcal infection and activation of human astrocytes. PLoS One. 2015; 10(6):e0128431. PMID: 26030618; PMCID: PMC4452173.
    14. Kim BJ, Hancock BM, Bermudez A, Del Cid N, Reyes E, van Sorge NM, Lauth X, Smurthwaite CA, Hilton BJ, Stotland A, Banerjee A, Buchanan J, Wolkowicz R, Traver D, Doran KS. Bacterial induction of Snail1 contributes to blood-brain barrier disruption. J Clin Invest. 2015 Jun; 125(6):2473-83. PMID: 25961453; PMCID: PMC4497739.
    15. Patras KA, Rösler B, Thoman ML, Doran KS. Characterization of host immunity during persistent vaginal colonization by Group B Streptococcus. Mucosal Immunol. 2015 Nov; 8(6):1339-48. PMID: 25850655; PMCID: PMC4598252.
    16. Kim BJ, Hancock BM, Del Cid N, Bermudez A, Traver D, Doran KS. Streptococcus agalactiae infection in zebrafish larvae. Microb Pathog. 2015 Feb; 79:57-60. PMID: 25617657; PMCID: PMC4340774.
    17. Gendrin C, Lembo A, Whidbey C, Burnside K, Berry J, Ngo L, Banerjee A, Xue L, Arrington J, Doran KS, Tao WA, Rajagopal L. The sensor histidine kinase RgfC affects group B streptococcal virulence factor expression independent of its response regulator RgfA. Infect Immun. 2015 Mar; 83(3):1078-88. PMID: 25561709; PMCID: PMC4333453.
    18. Cutting AS, Del Rosario Y, Mu R, Rodriguez A, Till A, Subramani S, Gottlieb RA, Doran KS. The role of autophagy during group B Streptococcus infection of blood-brain barrier endothelium. J Biol Chem. 2014 Dec 26; 289(52):35711-23. PMID: 25371213; PMCID: PMC4276841.
    19. Faralla C, Metruccio MM, De Chiara M, Mu R, Patras KA, Muzzi A, Grandi G, Margarit I, Doran KS, Janulczyk R. Analysis of two-component systems in group B Streptococcus shows that RgfAC and the novel FspSR modulate virulence and bacterial fitness. MBio. 2014 May 20; 5(3):e00870-14. PMID: 24846378; PMCID: PMC4030450.
    20. Robinson SM, Tsueng G, Sin J, Mangale V, Rahawi S, McIntyre LL, Williams W, Kha N, Cruz C, Hancock BM, Nguyen DP, Sayen MR, Hilton BJ, Doran KS, Segall AM, Wolkowicz R, Cornell CT, Whitton JL, Gottlieb RA, Feuer R. Coxsackievirus B exits the host cell in shed microvesicles displaying autophagosomal markers. PLoS Pathog. 2014 Apr; 10(4):e1004045. PMID: 24722773; PMCID: PMC3983045.
    21. Mu R, Kim BJ, Paco C, Del Rosario Y, Courtney HS, Doran KS. Identification of a group B streptococcal fibronectin binding protein, SfbA, that contributes to invasion of brain endothelium and development of meningitis. Infect Immun. 2014 Jun; 82(6):2276-86. PMID: 24643538; PMCID: PMC4019170.
    22. Wang NY, Patras KA, Seo HS, Cavaco CK, Rösler B, Neely MN, Sullam PM, Doran KS. Group B streptococcal serine-rich repeat proteins promote interaction with fibrinogen and vaginal colonization. J Infect Dis. 2014 Sep 15; 210(6):982-91. PMID: 24620021; PMCID: PMC4192050.
    23. Puccini JM, Ruller CM, Robinson SM, Knopp KA, Buchmeier MJ, Doran KS, Feuer R. Distinct neural stem cell tropism, early immune activation, and choroid plexus pathology following coxsackievirus infection in the neonatal central nervous system. Lab Invest. 2014 Feb; 94(2):161-81. PMID: 24378643.
      View in: PubMed
    24. Seo HS, Minasov G, Seepersaud R, Doran KS, Dubrovska I, Shuvalova L, Anderson WF, Iverson TM, Sullam PM. Characterization of fibrinogen binding by glycoproteins Srr1 and Srr2 of Streptococcus agalactiae. J Biol Chem. 2013 Dec 13; 288(50):35982-96. PMID: 24165132; PMCID: PMC3861647.
    25. Banerjee A, Thamphiwatana S, Carmona EM, Rickman B, Doran KS, Obonyo M. Deficiency of the myeloid differentiation primary response molecule MyD88 leads to an early and rapid development of Helicobacter-induced gastric malignancy. Infect Immun. 2014 Jan; 82(1):356-63. PMID: 24166959; PMCID: PMC3911874.
    26. Cavaco CK, Patras KA, Zlamal JE, Thoman ML, Morgan EL, Sanderson SD, Doran KS. A novel C5a-derived immunobiotic peptide reduces Streptococcus agalactiae colonization through targeted bacterial killing. Antimicrob Agents Chemother. 2013 Nov; 57(11):5492-9. PMID: 23979760; PMCID: PMC3811312.
    27. Doran KS, Banerjee A, Disson O, Lecuit M. Concepts and mechanisms: crossing host barriers. Cold Spring Harb Perspect Med. 2013 Jul 01; 3(7). PMID: 23818514; PMCID: PMC3685877.
    28. Barr JJ, Auro R, Furlan M, Whiteson KL, Erb ML, Pogliano J, Stotland A, Wolkowicz R, Cutting AS, Doran KS, Salamon P, Youle M, Rohwer F. Bacteriophage adhering to mucus provide a non-host-derived immunity. Proc Natl Acad Sci U S A. 2013 Jun 25; 110(26):10771-6. PMID: 23690590; PMCID: PMC3696810.
    29. Krishnan V, Dwivedi P, Kim BJ, Samal A, Macon K, Ma X, Mishra A, Doran KS, Ton-That H, Narayana SV. Structure of Streptococcus agalactiae tip pilin GBS104: a model for GBS pili assembly and host interactions. Acta Crystallogr D Biol Crystallogr. 2013 Jun; 69(Pt 6):1073-89. PMID: 23695252; PMCID: PMC3663123.
    30. Patras KA, Wang NY, Fletcher EM, Cavaco CK, Jimenez A, Garg M, Fierer J, Sheen TR, Rajagopal L, Doran KS. Group B Streptococcus CovR regulation modulates host immune signalling pathways to promote vaginal colonization. Cell Microbiol. 2013 Jul; 15(7):1154-67. PMID: 23298320; PMCID: PMC3657335.
    31. Seo HS, Mu R, Kim BJ, Doran KS, Sullam PM. Binding of glycoprotein Srr1 of Streptococcus agalactiae to fibrinogen promotes attachment to brain endothelium and the development of meningitis. PLoS Pathog. 2012; 8(10):e1002947. PMID: 23055927; PMCID: PMC3464228.
    32. Alkuwaity K, Taylor A, Heckels JE, Doran KS, Christodoulides M. Group B Streptococcus interactions with human meningeal cells and astrocytes in vitro. PLoS One. 2012; 7(8):e42660. PMID: 22900037; PMCID: PMC3416839.
    33. van Sorge NM, Doran KS. Defense at the border: the blood-brain barrier versus bacterial foreigners. Future Microbiol. 2012 Mar; 7(3):383-94. PMID: 22393891; PMCID: PMC3589978.
    34. Burnside K, Lembo A, Harrell MI, Gurney M, Xue L, BinhTran NT, Connelly JE, Jewell KA, Schmidt BZ, de los Reyes M, Tao WA, Doran KS, Rajagopal L. Serine/threonine phosphatase Stp1 mediates post-transcriptional regulation of hemolysin, autolysis, and virulence of group B Streptococcus. J Biol Chem. 2011 Dec 23; 286(51):44197-210. PMID: 22081606; PMCID: PMC3243546.
    35. Sheen TR, Cavaco CK, Ebrahimi CM, Thoman ML, Sanderson SD, Morgan EL, Doran KS. Control of methicillin resistant Staphylococcus aureus infection utilizing a novel immunostimulatory peptide. Vaccine. 2011 Dec 09; 30(1):9-13. PMID: 22044742; PMCID: PMC3229650.
    36. Sheen TR, Jimenez A, Wang NY, Banerjee A, van Sorge NM, Doran KS. Serine-rich repeat proteins and pili promote Streptococcus agalactiae colonization of the vaginal tract. J Bacteriol. 2011 Dec; 193(24):6834-42. PMID: 21984789; PMCID: PMC3232834.
    37. Banerjee A, Kim BJ, Carmona EM, Cutting AS, Gurney MA, Carlos C, Feuer R, Prasadarao NV, Doran KS. Bacterial Pili exploit integrin machinery to promote immune activation and efficient blood-brain barrier penetration. Nat Commun. 2011 Sep 06; 2:462. PMID: 21897373; PMCID: PMC3195231.
    38. Ebrahimi CM, Sheen TR, Renken CW, Gottlieb RA, Doran KS. Contribution of lethal toxin and edema toxin to the pathogenesis of anthrax meningitis. Infect Immun. 2011 Jul; 79(7):2510-8. PMID: 21518787; PMCID: PMC3191953.
    39. van Sorge NM, Zialcita PA, Browne SH, Quach D, Guiney DG, Doran KS. Penetration and activation of brain endothelium by Salmonella enterica serovar Typhimurium. J Infect Dis. 2011 Feb 01; 203(3):401-5. PMID: 21186258; PMCID: PMC3071103.
    40. Tabor-Godwin JM, Ruller CM, Bagalso N, An N, Pagarigan RR, Harkins S, Gilbert PE, Kiosses WB, Gude NA, Cornell CT, Doran KS, Sussman MA, Whitton JL, Feuer R. A novel population of myeloid cells responding to coxsackievirus infection assists in the dissemination of virus within the neonatal CNS. J Neurosci. 2010 Jun 23; 30(25):8676-91. PMID: 20573913; PMCID: PMC2902258.
    41. Banerjee A, Van Sorge NM, Sheen TR, Uchiyama S, Mitchell TJ, Doran KS. Activation of brain endothelium by pneumococcal neuraminidase NanA promotes bacterial internalization. Cell Microbiol. 2010 Nov; 12(11):1576-88. PMID: 20557315; PMCID: PMC2943548.
    42. Lembo A, Gurney MA, Burnside K, Banerjee A, de los Reyes M, Connelly JE, Lin WJ, Jewell KA, Vo A, Renken CW, Doran KS, Rajagopal L. Regulation of CovR expression in Group B Streptococcus impacts blood-brain barrier penetration. Mol Microbiol. 2010 Jul; 77(2):431-43. PMID: 20497331; PMCID: PMC2909351.
    43. Sheen TR, Ebrahimi CM, Hiemstra IH, Barlow SB, Peschel A, Doran KS. Penetration of the blood-brain barrier by Staphylococcus aureus: contribution of membrane-anchored lipoteichoic acid. J Mol Med (Berl). 2010 Jun; 88(6):633-9. PMID: 20419283; PMCID: PMC2893325.
    44. Ebrahimi CM, Kern JW, Sheen TR, Ebrahimi-Fardooee MA, van Sorge NM, Schneewind O, Doran KS. Penetration of the blood-brain barrier by Bacillus anthracis requires the pXO1-encoded BslA protein. J Bacteriol. 2009 Dec; 191(23):7165-73. PMID: 19820089; PMCID: PMC2786561.
    45. Uchiyama S, Carlin AF, Khosravi A, Weiman S, Banerjee A, Quach D, Hightower G, Mitchell TJ, Doran KS, Nizet V. The surface-anchored NanA protein promotes pneumococcal brain endothelial cell invasion. J Exp Med. 2009 Aug 31; 206(9):1845-52. PMID: 19687228; PMCID: PMC2737157.
    46. van Sorge NM, Quach D, Gurney MA, Sullam PM, Nizet V, Doran KS. The group B streptococcal serine-rich repeat 1 glycoprotein mediates penetration of the blood-brain barrier. J Infect Dis. 2009 May 15; 199(10):1479-87. PMID: 19392623; PMCID: PMC2674616.
    47. Quach D, van Sorge NM, Kristian SA, Bryan JD, Shelver DW, Doran KS. The CiaR response regulator in group B Streptococcus promotes intracellular survival and resistance to innate immune defenses. J Bacteriol. 2009 Apr; 191(7):2023-32. PMID: 19114476; PMCID: PMC2655536.
    48. Maisey HC, Doran KS, Nizet V. Recent advances in understanding the molecular basis of group B Streptococcus virulence. Expert Rev Mol Med. 2008 Sep 22; 10:e27. PMID: 18803886; PMCID: PMC2676346.
    49. van Sorge NM, Ebrahimi CM, McGillivray SM, Quach D, Sabet M, Guiney DG, Doran KS. Anthrax toxins inhibit neutrophil signaling pathways in brain endothelium and contribute to the pathogenesis of meningitis. PLoS One. 2008 Aug 13; 3(8):e2964. PMID: 18698416; PMCID: PMC2493037.
    50. Kaplan A, Chung K, Kocak H, Bertolotto C, Uh A, Hobel CJ, Simmons CF, Doran K, Liu GY, Equils O. Group B streptococcus induces trophoblast death. Microb Pathog. 2008 Sep; 45(3):231-5. PMID: 18599257; PMCID: PMC2610016.
    51. Maisey HC, Quach D, Hensler ME, Liu GY, Gallo RL, Nizet V, Doran KS. A group B streptococcal pilus protein promotes phagocyte resistance and systemic virulence. FASEB J. 2008 Jun; 22(6):1715-24. PMID: 18198218; PMCID: PMC2721339.
    52. Hensler ME, Quach D, Hsieh CJ, Doran KS, Nizet V. CAMP factor is not essential for systemic virulence of Group B Streptococcus. Microb Pathog. 2008 Jan; 44(1):84-8. PMID: 17870297; PMCID: PMC2247369.
    53. Kwinn LA, Khosravi A, Aziz RK, Timmer AM, Doran KS, Kotb M, Nizet V. Genetic characterization and virulence role of the RALP3/LSA locus upstream of the streptolysin s operon in invasive M1T1 Group A Streptococcus. J Bacteriol. 2007 Feb; 189(4):1322-9. PMID: 17114267; PMCID: PMC1797346.
    54. Maisey HC, Hensler M, Nizet V, Doran KS. Group B streptococcal pilus proteins contribute to adherence to and invasion of brain microvascular endothelial cells. J Bacteriol. 2007 Feb; 189(4):1464-7. PMID: 17041051; PMCID: PMC1797338.
    55. Doran KS, Engelson EJ, Khosravi A, Maisey HC, Fedtke I, Equils O, Michelsen KS, Arditi M, Peschel A, Nizet V. Blood-brain barrier invasion by group B Streptococcus depends upon proper cell-surface anchoring of lipoteichoic acid. J Clin Invest. 2005 Sep; 115(9):2499-507. PMID: 16138192; PMCID: PMC1193870.
    56. Doran KS, Nizet V. Molecular pathogenesis of neonatal group B streptococcal infection: no longer in its infancy. Mol Microbiol. 2004 Oct; 54(1):23-31. PMID: 15458402.
      View in: PubMed
    57. Liu GY, Doran KS, Lawrence T, Turkson N, Puliti M, Tissi L, Nizet V. Sword and shield: linked group B streptococcal beta-hemolysin/cytolysin and carotenoid pigment function to subvert host phagocyte defense. Proc Natl Acad Sci U S A. 2004 Oct 05; 101(40):14491-6. PMID: 15381763; PMCID: PMC521972.
    58. Doran KS, Liu GY, Nizet V. Group B streptococcal beta-hemolysin/cytolysin activates neutrophil signaling pathways in brain endothelium and contributes to development of meningitis. J Clin Invest. 2003 Sep; 112(5):736-44. PMID: 12952922; PMCID: PMC182187.
    59. Doran KS, Benoit VM, Gertz RE, Beall B, Nizet V. Late-onset group B streptococcal infection in identical twins: insight to disease pathogenesis. J Perinatol. 2002 Jun; 22(4):326-30. PMID: 12032798.
      View in: PubMed
    60. Doran KS, Chang JC, Benoit VM, Eckmann L, Nizet V. Group B streptococcal beta-hemolysin/cytolysin promotes invasion of human lung epithelial cells and the release of interleukin-8. J Infect Dis. 2002 Jan 15; 185(2):196-203. PMID: 11807693.
      View in: PubMed
    61. Doran KS, Helinski DR, Konieczny I. Host-dependent requirement for specific DnaA boxes for plasmid RK2 replication. Mol Microbiol. 1999 Aug; 33(3):490-8. PMID: 10417640.
      View in: PubMed
    62. Doran KS, Helinski DR, Konieczny I. A critical DnaA box directs the cooperative binding of the Escherichia coli DnaA protein to the plasmid RK2 replication origin. J Biol Chem. 1999 Jun 18; 274(25):17918-23. PMID: 10364238.
      View in: PubMed
    63. Doran KS, Konieczny I, Helinski DR. Replication origin of the broad host range plasmid RK2. Positioning of various motifs is critical for initiation of replication. J Biol Chem. 1998 Apr 03; 273(14):8447-53. PMID: 9525957.
      View in: PubMed
    64. Konieczny I, Doran KS, Helinski DR, Blasina A. Role of TrfA and DnaA proteins in origin opening during initiation of DNA replication of the broad host range plasmid RK2. J Biol Chem. 1997 Aug 08; 272(32):20173-8. PMID: 9242693.
      View in: PubMed
    Doran's Networks
    Click the "See All" links for more information and interactive visualizations!
    Concepts Expand Description
    _
    Co-Authors Expand Description
    _
    Similar People Expand Description
    _
    Same Department Expand Description
    Physical Neighbors Expand Description
    _

    Copyright © 2017 The Regents of the University of Colorado, a body corporate. All rights reserved. (Harvard PROFILES RNS software version: 2.10.0)