Colorado PROFILES, The Colorado Clinical and Translational Sciences Institute (CCTSI)
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Last Name
Institution

Anthony Wei Peng

TitleAssociate Professor
InstitutionUniversity of Colorado Denver - Anschutz Medical Campus
DepartmentSOM-PHYS General Operations

    Collapse Research 
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    R01AG073997     (RENNIE, KATHERINE JANET)Sep 5, 2021 - May 31, 2026
    NIH
    Aging and Dysfunction in the Peripheral Vestibular System
    Role: Co-Principal Investigator
    R01DC016868     (PENG, ANTHONY WEI)Jun 7, 2018 - Nov 30, 2028
    NIH
    Molecular mechanisms of cochlear hair bundle mechanics
    Role: Principal Investigator
    R00DC013299     (PENG, ANTHONY WEI)Aug 1, 2015 - Jul 31, 2018
    NIH
    Molecular roles in active and passive mechanics in cochlear hair bundles
    Role: Principal Investigator
    K99DC013299     (PENG, ANTHONY WEI)Jul 1, 2013 - Jul 31, 2015
    NIH
    Molecular roles in active and passive mechanics in cochlear hair bundles
    Role: Principal Investigator
    F32DC010975     (PENG, ANTHONY WEI)May 1, 2010 - Apr 30, 2013
    NIH
    Second messenger regulation of hair cell mechanotransduction
    Role: Principal Investigator
    F31DC009168     (PENG, ANTHONY WEI)Sep 1, 2007 - Aug 31, 2008
    NIH
    Inner Ear Hair Bundle Proteomics
    Role: Principal Investigator

    Collapse Bibliographic 
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    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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    1. Li S, Park J, Phan TM, Caprara GA, Sittipongpittaya N, Sheynkman GM, Peng AW, Egelman EH, Bird JE, Shin JB. Tonotopic specialization of MYO7A isoforms in auditory hair cells. Nat Commun. 2026 Jun 03. PMID: 42236700.
      View in: PubMed
    2. Sun C, Zhao J, Li N, Yao X, Wang Y, Kim CH, Bok J, Peng AW, Xu Z. Alternative splicing of the Rbm24 gene is essential for cochlear hair cell stereocilia integrity and hearing function in mice. Proc Natl Acad Sci U S A. 2026 Apr 21; 123(16):e2531564123. PMID: 41973913.
      View in: PubMed
    3. Li S, Jun S, Kim YR, Gogineni A, Lee F, Kim CH, Kim UK, Peng AW, Shin JB. A regulatory axis for tonotopic MYO7A expression in cochlear hair cells. Proc Natl Acad Sci U S A. 2026 Apr 14; 123(15):e2519742123. PMID: 41945437.
      View in: PubMed
    4. Alexandris AS, Yi J, Liu C, Belamarich J, Alam Z, Vats A, Peng A, Welsbie DS, Zack DJ, Koliatsos VE. Recovery of Retinal Terminal Fields after Traumatic Brain Injury: Evidence of Collateral Sprouting and Sexual Dimorphism. J Neurosci. 2026 02 04; 46(5). PMID: 41397889.
      View in: PubMed
    5. Dondzillo A, Bauer T, King K, Peng A, Rennie KJ. Quantifying calretinin-labeled afferent terminals in vestibular sensory epithelia of young and older gerbils. Neurobiol Aging. 2026 05; 161:73-82. PMID: 41653640.
      View in: PubMed
    6. Alexandris AS, Yi J, Liu C, Belamarich J, Alam Z, Vats A, Peng A, Welsbie DS, Zack DJ, Koliatsos VE. Recovery of retinal terminal fields after traumatic brain injury: evidence of collateral sprouting and sexual dimorphism. bioRxiv. 2025 Oct 03. PMID: 40575582.
      View in: PubMed
    7. Li S, Jun S, Kim Y, Gogineni A, Lee F, Kim CH, Kim UK, Peng AW, Shin JB. A Tonotopic Regulatory Axis Governing Isoform-Specific MYO7A Expression in Cochlear Hair Cells. bioRxiv. 2025 Apr 05. PMID: 40236169.
      View in: PubMed
    8. Mecca AA, Caprara GA, Peng AW. cAMP and voltage modulate rat auditory mechanotransduction by decreasing the stiffness of gating springs. Proc Natl Acad Sci U S A. 2022 07 26; 119(30):e2107567119. PMID: 35858439.
      View in: PubMed
    9. Caprara GA, Peng AW. Mechanotransduction in mammalian sensory hair cells. Mol Cell Neurosci. 2022 05; 120:103706. PMID: 35218890.
      View in: PubMed
    10. Xu Z, Peng AW, Xiong W. Editorial: Hair Bundles-Development, Maintenance, and Function. Front Cell Dev Biol. 2021; 9:800410. PMID: 34869395.
      View in: PubMed
    11. Peng AW, Scharr AL, Caprara GA, Nettles D, Steele CR, Ricci AJ. Fluid Jet Stimulation of Auditory Hair Bundles Reveal Spatial Non-uniformities and Two Viscoelastic-Like Mechanisms. Front Cell Dev Biol. 2021; 9:725101. PMID: 34513845.
      View in: PubMed
    12. Caprara GA, Mecca AA, Peng AW. Decades-old model of slow adaptation in sensory hair cells is not supported in mammals. Sci Adv. 2020 08; 6(33):eabb4922. PMID: 32851178.
      View in: PubMed
    13. Li S, Mecca A, Kim J, Caprara GA, Wagner EL, Du TT, Petrov L, Xu W, Cui R, Rebustini IT, Kachar B, Peng AW, Shin JB. Myosin-VIIa is expressed in multiple isoforms and essential for tensioning the hair cell mechanotransduction complex. Nat Commun. 2020 04 29; 11(1):2066. PMID: 32350269.
      View in: PubMed
    14. Caprara GA, Mecca AA, Wang Y, Ricci AJ, Peng AW. Hair Bundle Stimulation Mode Modifies Manifestations of Mechanotransduction Adaptation. J Neurosci. 2019 11 13; 39(46):9098-9106. PMID: 31578232.
      View in: PubMed
    15. Tilley DC, Angueyra JM, Eum KS, Kim H, Chao LH, Peng AW, Sack JT. The tarantula toxin GxTx detains K+ channel gating charges in their resting conformation. J Gen Physiol. 2019 03 04; 151(3):292-315. PMID: 30397012.
      View in: PubMed
    16. Effertz T, Becker L, Peng AW, Ricci AJ. Phosphoinositol-4,5-Bisphosphate Regulates Auditory Hair-Cell Mechanotransduction-Channel Pore Properties and Fast Adaptation. J Neurosci. 2017 11 29; 37(48):11632-11646. PMID: 29066559.
      View in: PubMed
    17. Kazmierczak M, Kazmierczak P, Peng AW, Harris SL, Shah P, Puel JL, Lenoir M, Franco SJ, Schwander M. Pejvakin, a Candidate Stereociliary Rootlet Protein, Regulates Hair Cell Function in a Cell-Autonomous Manner. J Neurosci. 2017 03 29; 37(13):3447-3464. PMID: 28209736.
      View in: PubMed
    18. Peng AW, Gnanasambandam R, Sachs F, Ricci AJ. Adaptation Independent Modulation of Auditory Hair Cell Mechanotransduction Channel Open Probability Implicates a Role for the Lipid Bilayer. J Neurosci. 2016 Mar 09; 36(10):2945-56. PMID: 26961949.
      View in: PubMed
    19. Peng AW, Ricci AJ. Glass Probe Stimulation of Hair Cell Stereocilia. Methods Mol Biol. 2016; 1427:487-500. PMID: 27259944.
      View in: PubMed
    20. Nam JH, Peng AW, Ricci AJ. Underestimated sensitivity of mammalian cochlear hair cells due to splay between stereociliary columns. Biophys J. 2015 Jun 02; 108(11):2633-47. PMID: 26039165.
      View in: PubMed
    21. Peng AW, Effertz T, Ricci AJ. Adaptation of mammalian auditory hair cell mechanotransduction is independent of calcium entry. Neuron. 2013 Nov 20; 80(4):960-72. PMID: 24267652.
      View in: PubMed
    22. Doll JC, Peng AW, Ricci AJ, Pruitt BL. Faster than the speed of hearing: nanomechanical force probes enable the electromechanical observation of cochlear hair cells. Nano Lett. 2012 Dec 12; 12(12):6107-11. PMID: 23181721.
      View in: PubMed
    23. Castellano-Muñoz M, Peng AW, Salles FT, Ricci AJ. Swept field laser confocal microscopy for enhanced spatial and temporal resolution in live-cell imaging. Microsc Microanal. 2012 Aug; 18(4):753-60. PMID: 22831554.
      View in: PubMed
    24. Peng AW, Salles FT, Pan B, Ricci AJ. Integrating the biophysical and molecular mechanisms of auditory hair cell mechanotransduction. Nat Commun. 2011 Nov 01; 2:523. PMID: 22045002.
      View in: PubMed
    25. Oshima K, Shin K, Diensthuber M, Peng AW, Ricci AJ, Heller S. Mechanosensitive hair cell-like cells from embryonic and induced pluripotent stem cells. Cell. 2010 May 14; 141(4):704-16. PMID: 20478259.
      View in: PubMed
    26. Peng AW, Ricci AJ. Somatic motility and hair bundle mechanics, are both necessary for cochlear amplification? Hear Res. 2011 Mar; 273(1-2):109-22. PMID: 20430075.
      View in: PubMed
    27. Peng AW, Belyantseva IA, Hsu PD, Friedman TB, Heller S. Twinfilin 2 regulates actin filament lengths in cochlear stereocilia. J Neurosci. 2009 Dec 02; 29(48):15083-8. PMID: 19955359.
      View in: PubMed
    28. Xu Z, Peng AW, Oshima K, Heller S. MAGI-1, a candidate stereociliary scaffolding protein, associates with the tip-link component cadherin 23. J Neurosci. 2008 Oct 29; 28(44):11269-76. PMID: 18971469.
      View in: PubMed
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