Colorado PROFILES, The Colorado Clinical and Translational Sciences Institute (CCTSI)
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Last Name
Institution

Anthony Wei Peng

TitleAssociate Professor
InstitutionUniversity of Colorado Denver - Anschutz Medical Campus
DepartmentSOM-PHYS General Operations

    Collapse Research 
    Collapse research activities and funding
    R01AG073997     (RENNIE, KATHERINE JANET)Sep 5, 2021 - May 31, 2026
    NIH
    Aging and Dysfunction in the Peripheral Vestibular System
    Role: Co-Principal Investigator
    R01DC016868     (PENG, ANTHONY WEI)Jun 7, 2018 - Nov 30, 2028
    NIH
    Molecular mechanisms of cochlear hair bundle mechanics
    Role: Principal Investigator
    R00DC013299     (PENG, ANTHONY WEI)Aug 1, 2015 - Jul 31, 2018
    NIH
    Molecular roles in active and passive mechanics in cochlear hair bundles
    Role: Principal Investigator
    K99DC013299     (PENG, ANTHONY WEI)Jul 1, 2013 - Jul 31, 2015
    NIH
    Molecular roles in active and passive mechanics in cochlear hair bundles
    Role: Principal Investigator
    F32DC010975     (PENG, ANTHONY WEI)May 1, 2010 - Apr 30, 2013
    NIH
    Second messenger regulation of hair cell mechanotransduction
    Role: Principal Investigator
    F31DC009168     (PENG, ANTHONY WEI)Sep 1, 2007 - Aug 31, 2008
    NIH
    Inner Ear Hair Bundle Proteomics
    Role: Principal Investigator

    Collapse Bibliographic 
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    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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    1. Mecca AA, Caprara GA, Peng AW. cAMP and voltage modulate rat auditory mechanotransduction by decreasing the stiffness of gating springs. Proc Natl Acad Sci U S A. 2022 07 26; 119(30):e2107567119. PMID: 35858439.
      View in: PubMed
    2. Caprara GA, Peng AW. Mechanotransduction in mammalian sensory hair cells. Mol Cell Neurosci. 2022 05; 120:103706. PMID: 35218890.
      View in: PubMed
    3. Peng AW, Scharr AL, Caprara GA, Nettles D, Steele CR, Ricci AJ. Fluid Jet Stimulation of Auditory Hair Bundles Reveal Spatial Non-uniformities and Two Viscoelastic-Like Mechanisms. Front Cell Dev Biol. 2021; 9:725101. PMID: 34513845.
      View in: PubMed
    4. Caprara GA, Mecca AA, Peng AW. Decades-old model of slow adaptation in sensory hair cells is not supported in mammals. Sci Adv. 2020 08; 6(33):eabb4922. PMID: 32851178.
      View in: PubMed
    5. Li S, Mecca A, Kim J, Caprara GA, Wagner EL, Du TT, Petrov L, Xu W, Cui R, Rebustini IT, Kachar B, Peng AW, Shin JB. Myosin-VIIa is expressed in multiple isoforms and essential for tensioning the hair cell mechanotransduction complex. Nat Commun. 2020 04 29; 11(1):2066. PMID: 32350269.
      View in: PubMed
    6. Caprara GA, Mecca AA, Wang Y, Ricci AJ, Peng AW. Hair Bundle Stimulation Mode Modifies Manifestations of Mechanotransduction Adaptation. J Neurosci. 2019 11 13; 39(46):9098-9106. PMID: 31578232.
      View in: PubMed
    7. Effertz T, Becker L, Peng AW, Ricci AJ. Phosphoinositol-4,5-Bisphosphate Regulates Auditory Hair-Cell Mechanotransduction-Channel Pore Properties and Fast Adaptation. J Neurosci. 2017 11 29; 37(48):11632-11646. PMID: 29066559.
      View in: PubMed
    8. Kazmierczak M, Kazmierczak P, Peng AW, Harris SL, Shah P, Puel JL, Lenoir M, Franco SJ, Schwander M. Pejvakin, a Candidate Stereociliary Rootlet Protein, Regulates Hair Cell Function in a Cell-Autonomous Manner. J Neurosci. 2017 03 29; 37(13):3447-3464. PMID: 28209736.
      View in: PubMed
    9. Peng AW, Gnanasambandam R, Sachs F, Ricci AJ. Adaptation Independent Modulation of Auditory Hair Cell Mechanotransduction Channel Open Probability Implicates a Role for the Lipid Bilayer. J Neurosci. 2016 Mar 09; 36(10):2945-56. PMID: 26961949.
      View in: PubMed
    10. Peng AW, Ricci AJ. Glass Probe Stimulation of Hair Cell Stereocilia. Methods Mol Biol. 2016; 1427:487-500. PMID: 27259944.
      View in: PubMed
    11. Nam JH, Peng AW, Ricci AJ. Underestimated sensitivity of mammalian cochlear hair cells due to splay between stereociliary columns. Biophys J. 2015 Jun 02; 108(11):2633-47. PMID: 26039165.
      View in: PubMed
    12. Peng AW, Effertz T, Ricci AJ. Adaptation of mammalian auditory hair cell mechanotransduction is independent of calcium entry. Neuron. 2013 Nov 20; 80(4):960-72. PMID: 24267652.
      View in: PubMed
    13. Doll JC, Peng AW, Ricci AJ, Pruitt BL. Faster than the speed of hearing: nanomechanical force probes enable the electromechanical observation of cochlear hair cells. Nano Lett. 2012 Dec 12; 12(12):6107-11. PMID: 23181721.
      View in: PubMed
    14. Castellano-Mu?oz M, Peng AW, Salles FT, Ricci AJ. Swept field laser confocal microscopy for enhanced spatial and temporal resolution in live-cell imaging. Microsc Microanal. 2012 Aug; 18(4):753-60. PMID: 22831554.
      View in: PubMed
    15. Peng AW, Salles FT, Pan B, Ricci AJ. Integrating the biophysical and molecular mechanisms of auditory hair cell mechanotransduction. Nat Commun. 2011 Nov 01; 2:523. PMID: 22045002.
      View in: PubMed
    16. Oshima K, Shin K, Diensthuber M, Peng AW, Ricci AJ, Heller S. Mechanosensitive hair cell-like cells from embryonic and induced pluripotent stem cells. Cell. 2010 May 14; 141(4):704-16. PMID: 20478259.
      View in: PubMed
    17. Peng AW, Ricci AJ. Somatic motility and hair bundle mechanics, are both necessary for cochlear amplification? Hear Res. 2011 Mar; 273(1-2):109-22. PMID: 20430075.
      View in: PubMed
    18. Peng AW, Belyantseva IA, Hsu PD, Friedman TB, Heller S. Twinfilin 2 regulates actin filament lengths in cochlear stereocilia. J Neurosci. 2009 Dec 02; 29(48):15083-8. PMID: 19955359.
      View in: PubMed
    19. Xu Z, Peng AW, Oshima K, Heller S. MAGI-1, a candidate stereociliary scaffolding protein, associates with the tip-link component cadherin 23. J Neurosci. 2008 Oct 29; 28(44):11269-76. PMID: 18971469.
      View in: PubMed
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