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Brianne M Bettcher

TitleAsst Professor
InstitutionUniversity of Colorado Denver - Anschutz Medical Campus

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    K23AG042492     (BETTCHER, BRIANNE MAGOUIRK)Aug 15, 2012 - Jul 31, 2017
    Cognitive and Neural Correlates of Inflammation in Healthy Older Adults
    Role: Principal Investigator

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    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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    1. Casaletto KB, Staffaroni AM, Elahi F, Fox E, Crittenden PA, You M, Neuhaus J, Glymour M, Bettcher BM, Yaffe K, Kramer JH. Perceived Stress is Associated with Accelerated Monocyte/Macrophage Aging Trajectories in Clinically Normal Adults. Am J Geriatr Psychiatry. 2018 Sep; 26(9):952-963. PMID: 30017239.
      View in: PubMed
    2. Bettcher BM, Johnson SC, Fitch R, Casaletto KB, Heffernan KS, Asthana S, Zetterberg H, Blennow K, Carlsson CM, Neuhaus J, Bendlin BB, Kramer JH. Cerebrospinal Fluid and Plasma Levels of Inflammation Differentially Relate to CNS Markers of Alzheimer's Disease Pathology and Neuronal Damage. J Alzheimers Dis. 2018; 62(1):385-397. PMID: 29439331.
      View in: PubMed
    3. Casaletto KB, Elahi FM, Bettcher BM, Neuhaus J, Bendlin BB, Asthana S, Johnson SC, Yaffe K, Carlsson C, Blennow K, Zetterberg H, Kramer JH. Neurogranin, a synaptic protein, is associated with memory independent of Alzheimer biomarkers. Neurology. 2017 Oct 24; 89(17):1782-1788. PMID: 28939668.
      View in: PubMed
    4. Hamlett ED, Ledreux A, Potter H, Chial HJ, Patterson D, Espinosa JM, Bettcher BM, Granholm AC. Exosomal biomarkers in Down syndrome and Alzheimer's disease. Free Radic Biol Med. 2018 01; 114:110-121. PMID: 28882786.
      View in: PubMed
    5. Parthasarathy V, Frazier DT, Bettcher BM, Jastrzab L, Chao L, Reed B, Mungas D, Weiner M, DeCarli C, Chui H, Kramer JH. Triglycerides are negatively correlated with cognitive function in nondemented aging adults. Neuropsychology. 2017 Sep; 31(6):682-688. PMID: 28604016.
      View in: PubMed
    6. Bott NT, Bettcher BM, Yokoyama JS, Frazier DT, Wynn M, Karydas A, Yaffe K, Kramer JH. Youthful Processing Speed in Older Adults: Genetic, Biological, and Behavioral Predictors of Cognitive Processing Speed Trajectories in Aging. Front Aging Neurosci. 2017; 9:55. PMID: 28344553.
      View in: PubMed
    7. Bettcher BM, Ard MC, Reed BR, Benitez A, Simmons A, Larson EB, Sonnen JA, Montine TJ, Li G, Keene CD, Crane PK, Mungas D. Association between Cholesterol Exposure and Neuropathological Findings: The ACT Study. J Alzheimers Dis. 2017; 59(4):1307-1315. PMID: 28731431.
      View in: PubMed
    8. Casaletto KB, Ward ME, Baker NS, Bettcher BM, Gelfand JM, Li Y, Chen R, Dutt S, Miller B, Kramer JH, Green AJ. Retinal thinning is uniquely associated with medial temporal lobe atrophy in neurologically normal older adults. Neurobiol Aging. 2017 03; 51:141-147. PMID: 28068565.
      View in: PubMed
    9. Bertoux M, Sarazin M, Pasquier F, Bottlaender M, de Souza LC, Mioshi E, Hornberger M, Ranasinghe KG, Rankin KP, Lobach IV, Kramer JH, Sturm VE, Bettcher BM, Possin K, You SC, Lamarre AK, Shany-Ur T, Stephens ML, Perry DC, Lee SE, Miller ZA, Gorno-Tempini ML, Rosen HJ, Boxer A, Seeley WW, Rabinovici GD, Vossel KA, Miller BL. Cognition and neuropsychiatry in behavioral variant frontotemporal dementia by disease stage. Neurology. 2016 10 04; 87(14):1523. PMID: 27698154.
      View in: PubMed
    10. Ranasinghe KG, Rankin KP, Pressman PS, Perry DC, Lobach IV, Seeley WW, Coppola G, Karydas AM, Grinberg LT, Shany-Ur T, Lee SE, Rabinovici GD, Rosen HJ, Gorno-Tempini ML, Boxer AL, Miller ZA, Chiong W, DeMay M, Kramer JH, Possin KL, Sturm VE, Bettcher BM, Neylan M, Zackey DD, Nguyen LA, Ketelle R, Block N, Wu TQ, Dallich A, Russek N, Caplan A, Geschwind DH, Vossel KA, Miller BL. Distinct Subtypes of Behavioral Variant Frontotemporal Dementia Based on Patterns of Network Degeneration. JAMA Neurol. 2016 Sep 01; 73(9):1078-88. PMID: 27429218.
      View in: PubMed
    11. Bettcher BM, Fitch R, Wynn MJ, Lalli MA, Elofson J, Jastrzab L, Mitic L, Miller ZA, Rabinovici GD, Miller BL, Kao AW, Kosik KS, Kramer JH. MCP-1 and eotaxin-1 selectively and negatively associate with memory in MCI and Alzheimer's disease dementia phenotypes. Alzheimers Dement (Amst). 2016; 3:91-7. PMID: 27453930.
      View in: PubMed
    12. Bettcher BM, Mungas D, Patel N, Elofson J, Dutt S, Wynn M, Watson CL, Stephens M, Walsh CM, Kramer JH. Neuroanatomical substrates of executive functions: Beyond prefrontal structures. Neuropsychologia. 2016 05; 85:100-9. PMID: 26948072; PMCID: PMC4853308 [Available on 05/01/17].
    13. Ranasinghe KG, Rankin KP, Lobach IV, Kramer JH, Sturm VE, Bettcher BM, Possin K, Christine You S, Lamarre AK, Shany-Ur T, Stephens ML, Perry DC, Lee SE, Miller ZA, Gorno-Tempini ML, Rosen HJ, Boxer A, Seeley WW, Rabinovici GD, Vossel KA, Miller BL. Cognition and neuropsychiatry in behavioral variant frontotemporal dementia by disease stage. Neurology. 2016 Feb 16; 86(7):600-10. PMID: 26802093.
      View in: PubMed
    14. Lalli MA, Bettcher BM, Arcila ML, Garcia G, Guzman C, Madrigal L, Ramirez L, Acosta-Uribe J, Baena A, Wojta KJ, Coppola G, Fitch R, de Both MD, Huentelman MJ, Reiman EM, Brunkow ME, Glusman G, Roach JC, Kao AW, Lopera F, Kosik KS. Whole-genome sequencing suggests a chemokine gene cluster that modifies age at onset in familial Alzheimer's disease. Mol Psychiatry. 2015 Nov; 20(11):1294-300. PMID: 26324103.
      View in: PubMed
    15. Frazier DT, Bettcher BM, Dutt S, Patel N, Mungas D, Miller J, Green R, Kramer JH. Relationship between Insulin-Resistance Processing Speed and Specific Executive Function Profiles in Neurologically Intact Older Adults. J Int Neuropsychol Soc. 2015 Sep; 21(8):622-8. PMID: 26272269; PMCID: PMC4764989.
    16. Forner SA, Takada LT, Bettcher BM, Lobach IV, Tartaglia MC, Torres-Chae C, Haman A, Thai J, Vitali P, Neuhaus J, Bostrom A, Miller BL, Rosen HJ, Geschwind MD. Comparing CSF biomarkers and brain MRI in the diagnosis of sporadic Creutzfeldt-Jakob disease. Neurol Clin Pract. 2015 Apr; 5(2):116-125. PMID: 26137420.
      View in: PubMed
    17. Ossenkoppele R, Schonhaut DR, Baker SL, O'Neil JP, Janabi M, Ghosh PM, Santos M, Miller ZA, Bettcher BM, Gorno-Tempini ML, Miller BL, Jagust WJ, Rabinovici GD. Tau, amyloid, and hypometabolism in a patient with posterior cortical atrophy. Ann Neurol. 2015 Feb; 77(2):338-42. PMID: 25448043; PMCID: PMC4382124.
    18. Frazier DT, Seider T, Bettcher BM, Mack WJ, Jastrzab L, Chao L, Weiner MW, DeCarli C, Reed BR, Mungas D, Chui HC, Kramer JH. The role of carotid intima-media thickness in predicting longitudinal cognitive function in an older adult cohort. Cerebrovasc Dis. 2014; 38(6):441-7. PMID: 25502351; PMCID: PMC4303029.
    19. Bettcher BM, Yaffe K, Boudreau RM, Neuhaus J, Aizenstein H, Ding J, Kritchevsky SB, Launer LJ, Liu Y, Satterfield S, Rosano C. Declines in inflammation predict greater white matter microstructure in older adults. Neurobiol Aging. 2015 Feb; 36(2):948-54. PMID: 25554492.
      View in: PubMed
    20. Naasan G, Irani SR, Bettcher BM, Geschwind MD, Gelfand JM. Episodic bradycardia as neurocardiac prodrome to voltage-gated potassium channel complex/leucine-rich, glioma inactivated 1 antibody encephalitis. JAMA Neurol. 2014 Oct; 71(10):1300-4. PMID: 25133690; PMCID: PMC4474144.
    21. Bettcher BM, Watson CL, Walsh CM, Lobach IV, Neuhaus J, Miller JW, Green R, Patel N, Dutt S, Busovaca E, Rosen HJ, Yaffe K, Miller BL, Kramer JH. Interleukin-6, age, and corpus callosum integrity. PLoS One. 2014; 9(9):e106521. PMID: 25188448; PMCID: PMC4154691.
    22. Bettcher BM, Kramer JH. Longitudinal inflammation, cognitive decline, and Alzheimer's disease: a mini-review. Clin Pharmacol Ther. 2014 Oct; 96(4):464-9. PMID: 25009982; PMCID: PMC4224964.
    23. Bettcher BM, Gelfand JM, Irani SR, Neuhaus J, Forner S, Hess CP, Geschwind MD. More than memory impairment in voltage-gated potassium channel complex encephalopathy. Eur J Neurol. 2014 Oct; 21(10):1301-10. PMID: 24981998; PMCID: PMC4162838.
    24. Irani SR, Gelfand JM, Bettcher BM, Singhal NS, Geschwind MD. Effect of rituximab in patients with leucine-rich, glioma-inactivated 1 antibody-associated encephalopathy. JAMA Neurol. 2014 Jul 01; 71(7):896-900. PMID: 24842754; PMCID: PMC4477824.
    25. Caso F, Mandelli ML, Henry M, Gesierich B, Bettcher BM, Ogar J, Filippi M, Comi G, Magnani G, Sidhu M, Trojanowski JQ, Huang EJ, Grinberg LT, Miller BL, Dronkers N, Seeley WW, Gorno-Tempini ML. In vivo signatures of nonfluent/agrammatic primary progressive aphasia caused by FTLD pathology. Neurology. 2014 Jan 21; 82(3):239-47. PMID: 24353332; PMCID: PMC3902758.
    26. Kim MO, Cali I, Oehler A, Fong JC, Wong K, See T, Katz JS, Gambetti P, Bettcher BM, Dearmond SJ, Geschwind MD. Genetic CJD with a novel E200G mutation in the prion protein gene and comparison with E200K mutation cases. Acta Neuropathol Commun. 2013 Dec 12; 1:80. PMID: 24330864; PMCID: PMC3880091.
    27. Walsh CM, Wilkins S, Bettcher BM, Butler CR, Miller BL, Kramer JH. Memory consolidation in aging and MCI after 1 week. Neuropsychology. 2014 Mar; 28(2):273-80. PMID: 24219610; PMCID: PMC4211844.
    28. Bettcher BM, Walsh CM, Watson C, Miller JW, Green R, Patel N, Miller BL, Neuhaus J, Yaffe K, Kramer JH. Body mass and white matter integrity: the influence of vascular and inflammatory markers. PLoS One. 2013; 8(10):e77741. PMID: 24147070; PMCID: PMC3797689.
    29. Miller ZA, Mandelli ML, Rankin KP, Henry ML, Babiak MC, Frazier DT, Lobach IV, Bettcher BM, Wu TQ, Rabinovici GD, Graff-Radford NR, Miller BL, Gorno-Tempini ML. Handedness and language learning disability differentially distribute in progressive aphasia variants. Brain. 2013 Nov; 136(Pt 11):3461-73. PMID: 24056533; PMCID: PMC3808687.
    30. Giovannetti T, Britnell P, Brennan L, Siderowf A, Grossman M, Libon DJ, Bettcher BM, Rouzard F, Eppig J, Seidel GA. Everyday action impairment in Parkinson's disease dementia. J Int Neuropsychol Soc. 2012 Sep; 18(5):787-98. PMID: 22621995; PMCID: PMC3648638.
    31. Bettcher BM, Kramer JH. Inflammation and clinical presentation in neurodegenerative disease: a volatile relationship. Neurocase. 2013 Apr; 19(2):182-200. PMID: 22515699; PMCID: PMC3733377.
    32. Bettcher BM, Giovannetti T, Libon DJ, Eppig J, Wambach D, Klobusicky E. Improving everyday error detection, one picture at a time: a performance-based study of everyday task training. Neuropsychology. 2011 Nov; 25(6):771-83. PMID: 21639639.
      View in: PubMed
    33. Eppig J, Wambach D, Nieves C, Price CC, Lamar M, Delano-Wood L, Giovannetti T, Bettcher BM, Penney DL, Swenson R, Lippa C, Kabasakalian A, Bondi MW, Libon DJ. Dysexecutive functioning in mild cognitive impairment: derailment in temporal gradients. J Int Neuropsychol Soc. 2012 Jan; 18(1):20-8. PMID: 22014116; PMCID: PMC3315354.
    34. Bettcher BM, Wilheim R, Rigby T, Green R, Miller JW, Racine CA, Yaffe K, Miller BL, Kramer JH. C-reactive protein is related to memory and medial temporal brain volume in older adults. Brain Behav Immun. 2012 Jan; 26(1):103-8. PMID: 21843630; PMCID: PMC3221922.
    35. Bettcher BM, Giovannetti T, Klobusicky E, Wambach D, Eppig J, Libon DJ. To err is human, to monitor divine: environmental adaptations reduce everyday errors but do not improve monitoring. J Clin Exp Neuropsychol. 2011 Dec; 33(10):1049-58. PMID: 22133138.
      View in: PubMed
    36. Giovannetti T, Bettcher BM, Brennan L, Libon DJ, Wambach D, Seter C. Target-related distractors disrupt object selection in everyday action: evidence from participants with dementia. J Int Neuropsychol Soc. 2010 May; 16(3):484-94. PMID: 20298638.
      View in: PubMed
    37. Libon DJ, Xie SX, Eppig J, Wicas G, Lamar M, Lippa C, Bettcher BM, Price CC, Giovannetti T, Swenson R, Wambach DM. The heterogeneity of mild cognitive impairment: a neuropsychological analysis. J Int Neuropsychol Soc. 2010 Jan; 16(1):84-93. PMID: 19887015.
      View in: PubMed
    38. Brennan L, Giovannetti T, Libon DJ, Bettcher BM, Duey K. The impact of goal cues on everyday action performance in dementia. Neuropsychol Rehabil. 2009 Aug; 19(4):562-82. PMID: 18923960.
      View in: PubMed
    39. Price CC, Garrett KD, Jefferson AL, Cosentino S, Tanner JJ, Penney DL, Swenson R, Giovannetti T, Bettcher BM, Libon DJ. Leukoaraiosis severity and list-learning in dementia. Clin Neuropsychol. 2009 Aug; 23(6):944-61. PMID: 19370451; PMCID: PMC2866111.
    40. Bettcher BM, Giovannetti T. From cognitive neuroscience to geriatric neuropsychology: what do current conceptualizations of the action error handling process mean for older adults? Neuropsychol Rev. 2009 Mar; 19(1):64-84. PMID: 19172399.
      View in: PubMed
    41. Giovannetti T, Hopkins MW, Crawford J, Bettcher BM, Schmidt KS, Libon DJ. Syntactic comprehension deficits are associated with MRI white matter alterations in dementia. J Int Neuropsychol Soc. 2008 Jul; 14(4):542-51. PMID: 18577283.
      View in: PubMed
    42. Giovannetti T, Bettcher BM, Brennan L, Libon DJ, Burke M, Duey K, Nieves C, Wambach D. Characterization of everyday functioning in mild cognitive impairment: a direct assessment approach. Dement Geriatr Cogn Disord. 2008; 25(4):359-65. PMID: 18340108.
      View in: PubMed
    43. Giovannetti T, Bettcher BM, Brennan L, Libron DJ, Kessler RK, Duey K. Coffee with jelly or unbuttered toast: commissions and omissions are dissociable aspects of everyday action impairment in Alzheimer's disease. Neuropsychology. 2008 Mar; 22(2):235-45. PMID: 18331166.
      View in: PubMed
    44. Bettcher BM, Giovannetti T, Macmullen L, Libon DJ. Error detection and correction patterns in dementia: a breakdown of error monitoring processes and their neuropsychological correlates. J Int Neuropsychol Soc. 2008 Mar; 14(2):199-208. PMID: 18282318.
      View in: PubMed
    45. Libon DJ, Price CC, Giovannetti T, Swenson R, Bettcher BM, Heilman KM, Pennisi A. Linking MRI hyperintensities with patterns of neuropsychological impairment: evidence for a threshold effect. Stroke. 2008 Mar; 39(3):806-13. PMID: 18258842.
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    46. Giovannetti T, Bettcher BM, Libon DJ, Brennan L, Sestito N, Kessler RK. Environmental adaptations improve everyday action performance in Alzheimer's disease: empirical support from performance-based assessment. Neuropsychology. 2007 Jul; 21(4):448-57. PMID: 17605578.
      View in: PubMed
    47. Byerly MJ, Nakonezny PA, Bettcher BM, Carmody T, Fisher R, Rush AJ. Sexual dysfunction associated with second-generation antipsychotics in outpatients with schizophrenia or schizoaffective disorder: an empirical evaluation of olanzapine, risperidone, and quetiapine. Schizophr Res. 2006 Sep; 86(1-3):244-50. PMID: 16730951.
      View in: PubMed
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