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Search Results to Patricia Ernst

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One or more keywords matched the following items that are connected to Ernst, Patricia

Item TypeName
Concept Oncogene Proteins, Fusion
Concept Oncogenes
Concept Proto-Oncogenes
Concept Oncogene Proteins
Concept Proto-Oncogene Proteins
Concept Proto-Oncogene Proteins c-kit
Concept Proto-Oncogene Proteins c-bcl-6
Academic Article Two decades of leukemia oncoprotein epistasis: the MLL1 paradigm for epigenetic deregulation in leukemia.
Academic Article An MLL-dependent network sustains hematopoiesis.
Academic Article MLL-AF9-induced leukemogenesis requires coexpression of the wild-type Mll allele.
Academic Article Conditional MLL-CBP targets GMP and models therapy-related myeloproliferative disease.
Academic Article An Mll-dependent Hox program drives hematopoietic progenitor expansion.
Academic Article Definitive hematopoiesis requires the mixed-lineage leukemia gene.
Academic Article Proteolytic cleavage of MLL generates a complex of N- and C-terminal fragments that confers protein stability and subnuclear localization.
Academic Article The role of MLL in hematopoiesis and leukemia.
Academic Article Distinct pathways regulated by menin and by MLL1 in hematopoietic stem cells and developing B cells.
Academic Article Acat1 gene ablation in mice increases hematopoietic progenitor cell proliferation in bone marrow and causes leukocytosis.
Academic Article Cell context in the control of self-renewal and proliferation regulated by MLL1.
Academic Article MLL1 and DOT1L cooperate with meningioma-1 to induce acute myeloid leukemia.
Academic Article Context, Context, Context: New Gene Programs Linked to Bad Behavior in MLL-AF9-Initiated Leukemia.
Academic Article Kmt2a cooperates with menin to suppress tumorigenesis in mouse pancreatic islets.
Academic Article NUP98 Fusion Proteins Interact with the NSL and MLL1 Complexes to Drive Leukemogenesis.
Grant MII Regulation of Hematopoiesis
Grant Molecular Pathways Regulated by the MLL Proto-Oncogene During Lymphopoiesis
Academic Article Distinct pathways affected by menin versus MLL1/MLL2 in MLL-rearranged acute myeloid leukemia.
Academic Article Hematopoietic transformation in the absence of MLL1/KMT2A: distinctions in target gene reactivation.
Academic Article Rationale for targeting BCL6 in MLL-rearranged acute lymphoblastic leukemia.
Grant Enhancing hematopoiesis through modulation of a histone methyltransferase: evaluating a new MLL1 gain-of-function animal model
Grant Identification of an embryonic cell-intrinsic cancer checkpoint: studying differential transcriptional effects of the proto-oncogene MLL1 versus MLL-ENL in an embryonic system
Academic Article Menin is necessary for long term maintenance of meningioma-1 driven leukemia.
Academic Article Discovery of first-in-class inhibitors of ASH1L histone methyltransferase with anti-leukemic activity.

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  • Oncogenes

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